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Items: 34


Microparticles as Potential Mediators of High Glucose-Induced Renal Cell Injury.

Ravindran S, Pasha M, Agouni A, Munusamy S.

Biomolecules. 2019 Aug 6;9(8). pii: E348. doi: 10.3390/biom9080348.


The Role of Protein Tyrosine Phosphatase (PTP)-1B in Cardiovascular Disease and Its Interplay with Insulin Resistance.

Abdelsalam SS, Korashy HM, Zeidan A, Agouni A.

Biomolecules. 2019 Jul 17;9(7). pii: E286. doi: 10.3390/biom9070286. Review.


Selenium and Health: An Update on the Situation in the Middle East and North Africa.

Ibrahim SAZ, Kerkadi A, Agouni A.

Nutrients. 2019 Jun 27;11(7). pii: E1457. doi: 10.3390/nu11071457.


Endoplasmic Reticulum Stress: A Critical Molecular Driver of Endothelial Dysfunction and Cardiovascular Disturbances Associated with Diabetes.

Maamoun H, Abdelsalam SS, Zeidan A, Korashy HM, Agouni A.

Int J Mol Sci. 2019 Apr 3;20(7). pii: E1658. doi: 10.3390/ijms20071658. Review.


There Is Selective Increase in Pro-thrombotic Circulating Extracellular Vesicles in Acute Ischemic Stroke and Transient Ischemic Attack: A Study of Patients From the Middle East and Southeast Asia.

Agouni A, Parray AS, Akhtar N, Mir FA, Bourke PJ, Joseph S, Morgan DM, Santos MD, Wadiwala MF, Kamran S, Sivaraman SK, Shuaib A.

Front Neurol. 2019 Mar 19;10:251. doi: 10.3389/fneur.2019.00251. eCollection 2019.


Molecular Mechanisms Underpinning Microparticle-Mediated Cellular Injury in Cardiovascular Complications Associated with Diabetes.

Benameur T, Osman A, Parray A, Ait Hssain A, Munusamy S, Agouni A.

Oxid Med Cell Longev. 2019 Feb 19;2019:6475187. doi: 10.1155/2019/6475187. eCollection 2019. Review.


Circulating microparticles as biomarkers of stroke: A focus on the value of endothelial- and platelet-derived microparticles.

El-Gamal H, Parray AS, Mir FA, Shuaib A, Agouni A.

J Cell Physiol. 2019 Aug;234(10):16739-16754. doi: 10.1002/jcp.28499. Epub 2019 Mar 25. Review.


Metformin Induces Different Responses in Clear Cell Renal Cell Carcinoma Caki Cell Lines.

Pasha M, Sivaraman SK, Frantz R, Agouni A, Munusamy S.

Biomolecules. 2019 Mar 22;9(3). pii: E113. doi: 10.3390/biom9030113.


Antioxidant Activity Mediates Pirfenidone Antifibrotic Effects in Human Pulmonary Vascular Smooth Muscle Cells Exposed to Sera of Idiopathic Pulmonary Fibrosis Patients.

Fois AG, Posadino AM, Giordo R, Cossu A, Agouni A, Rizk NM, Pirina P, Carru C, Zinellu A, Pintus G.

Oxid Med Cell Longev. 2018 Oct 21;2018:2639081. doi: 10.1155/2018/2639081. eCollection 2018.


Paradoxical Effect of Nonalcoholic Red Wine Polyphenol Extract, Provinols™, in the Regulation of Cyclooxygenases in Vessels from Zucker Fatty Rats (fa/fa).

Agouni A, Mostefai HA, Lagrue AH, Sladkova M, Rouet P, Desmoulin F, Pechanova O, Martínez MC, Andriantsitohaina R.

Oxid Med Cell Longev. 2017;2017:8536910. doi: 10.1155/2017/8536910. Epub 2017 Jun 4.


Comparison of the Protective Effects of Individual Components of Particulated trans-Sialidase (PTCTS), PTC and TS, against High Cholesterol Diet-Induced Atherosclerosis in Rabbits.

Garavelo SM, Higuchi ML, Pereira JJ, Reis MM, Kawakami JT, Ikegami RN, Palomino SA, Wadt NS, Agouni A.

Biomed Res Int. 2017;2017:7212985. doi: 10.1155/2017/7212985. Epub 2017 Feb 27.


Heme oxygenase (HO)-1 induction prevents Endoplasmic Reticulum stress-mediated endothelial cell death and impaired angiogenic capacity.

Maamoun H, Zachariah M, McVey JH, Green FR, Agouni A.

Biochem Pharmacol. 2017 Mar 1;127:46-59. doi: 10.1016/j.bcp.2016.12.009. Epub 2016 Dec 21.


Temporal Cross Talk Between Endoplasmic Reticulum and Mitochondria Regulates Oxidative Stress and Mediates Microparticle-Induced Endothelial Dysfunction.

Safiedeen Z, Rodríguez-Gómez I, Vergori L, Soleti R, Vaithilingam D, Douma I, Agouni A, Leiber D, Dubois S, Simard G, Zibara K, Andriantsitohaina R, Martínez MC.

Antioxid Redox Signal. 2017 Jan 1;26(1):15-27. doi: 10.1089/ars.2016.6771. Epub 2016 Aug 19.


Hepatic protein tyrosine phosphatase 1B (PTP1B) deficiency protects against obesity-induced endothelial dysfunction.

Agouni A, Tual-Chalot S, Chalopin M, Duluc L, Mody N, Martinez MC, Andriantsitohaina R, Delibegović M.

Biochem Pharmacol. 2014 Dec 15;92(4):607-17. doi: 10.1016/j.bcp.2014.10.008. Epub 2014 Oct 30.


Microparticles as biomarkers of vascular dysfunction in metabolic syndrome and its individual components.

Agouni A, Andriantsitohaina R, Martinez MC.

Curr Vasc Pharmacol. 2014 May;12(3):483-92. Review.


Myeloid-cell protein tyrosine phosphatase-1B deficiency in mice protects against high-fat diet and lipopolysaccharide-induced inflammation, hyperinsulinemia, and endotoxemia through an IL-10 STAT3-dependent mechanism.

Grant L, Shearer KD, Czopek A, Lees EK, Owen C, Agouni A, Workman J, Martin-Granados C, Forrester JV, Wilson HM, Mody N, Delibegovic M.

Diabetes. 2014 Feb;63(2):456-70. doi: 10.2337/db13-0885. Epub 2013 Nov 1.


Cellular apoptosis susceptibility (chromosome segregation 1-like, CSE1L) gene is a key regulator of apoptosis, migration and invasion in colorectal cancer.

Alnabulsi A, Agouni A, Mitra S, Garcia-Murillas I, Carpenter B, Bird S, Murray GI.

J Pathol. 2012 Dec;228(4):471-81. doi: 10.1002/path.4031. Epub 2012 Aug 20.


Adipocyte-specific protein tyrosine phosphatase 1B deletion increases lipogenesis, adipocyte cell size and is a minor regulator of glucose homeostasis.

Owen C, Czopek A, Agouni A, Grant L, Judson R, Lees EK, Mcilroy GD, Göransson O, Welch A, Bence KK, Kahn BB, Neel BG, Mody N, Delibegović M.

PLoS One. 2012;7(2):e32700. doi: 10.1371/journal.pone.0032700. Epub 2012 Feb 28.


Microparticles from patients with metabolic syndrome induce vascular hypo-reactivity via Fas/Fas-ligand pathway in mice.

Agouni A, Ducluzeau PH, Benameur T, Faure S, Sladkova M, Duluc L, Leftheriotis G, Pechanova O, Delibegovic M, Martinez MC, Andriantsitohaina R.

PLoS One. 2011;6(11):e27809. doi: 10.1371/journal.pone.0027809. Epub 2011 Nov 15.


Liver-specific deletion of protein tyrosine phosphatase (PTP) 1B improves obesity- and pharmacologically induced endoplasmic reticulum stress.

Agouni A, Mody N, Owen C, Czopek A, Zimmer D, Bentires-Alj M, Bence KK, Delibegović M.

Biochem J. 2011 Sep 1;438(2):369-78. doi: 10.1042/BJ20110373.


Role of G(i/o)-Src kinase-PI3K/Akt pathway and caveolin-1 in β₂-adrenoceptor coupling to endothelial NO synthase in mouse pulmonary artery.

Banquet S, Delannoy E, Agouni A, Dessy C, Lacomme S, Hubert F, Richard V, Muller B, Leblais V.

Cell Signal. 2011 Jul;23(7):1136-43. doi: 10.1016/j.cellsig.2011.02.008. Epub 2011 Mar 6.


Microparticles from apoptotic monocytes enhance nitrosative stress in human endothelial cells.

Mastronardi ML, Mostefai HA, Soleti R, Agouni A, Martínez MC, Andriantsitohaina R.

Fundam Clin Pharmacol. 2011 Dec;25(6):653-60. doi: 10.1111/j.1472-8206.2010.00898.x. Epub 2010 Nov 24.


In vivo differential effects of fasting, re-feeding, insulin and insulin stimulation time course on insulin signaling pathway components in peripheral tissues.

Agouni A, Owen C, Czopek A, Mody N, Delibegovic M.

Biochem Biophys Res Commun. 2010 Oct 8;401(1):104-11. doi: 10.1016/j.bbrc.2010.09.018. Epub 2010 Sep 15.


Endothelial dysfunction and circulating microparticles from patients with obstructive sleep apnea.

Priou P, Gagnadoux F, Tesse A, Mastronardi ML, Agouni A, Meslier N, Racineux JL, Martinez MC, Trzepizur W, Andriantsitohaina R.

Am J Pathol. 2010 Aug;177(2):974-83. doi: 10.2353/ajpath.2010.091252. Epub 2010 Jun 21.


Red wine polyphenols prevent metabolic and cardiovascular alterations associated with obesity in Zucker fatty rats (Fa/Fa).

Agouni A, Lagrue-Lak-Hal AH, Mostefai HA, Tesse A, Mulder P, Rouet P, Desmoulin F, Heymes C, Martínez MC, Andriantsitohaina R.

PLoS One. 2009;4(5):e5557. doi: 10.1371/journal.pone.0005557. Epub 2009 May 18.


Endothelial dysfunction caused by circulating microparticles from patients with metabolic syndrome.

Agouni A, Lagrue-Lak-Hal AH, Ducluzeau PH, Mostefai HA, Draunet-Busson C, Leftheriotis G, Heymes C, Martinez MC, Andriantsitohaina R.

Am J Pathol. 2008 Oct;173(4):1210-9. doi: 10.2353/ajpath.2008.080228. Epub 2008 Sep 4.


Circulating microparticles from patients with septic shock exert protective role in vascular function.

Mostefai HA, Meziani F, Mastronardi ML, Agouni A, Heymes C, Sargentini C, Asfar P, Martinez MC, Andriantsitohaina R.

Am J Respir Crit Care Med. 2008 Dec 1;178(11):1148-55. doi: 10.1164/rccm.200712-1835OC. Epub 2008 Aug 21.


Phosphatidylinositol 3-kinase and xanthine oxidase regulate nitric oxide and reactive oxygen species productions by apoptotic lymphocyte microparticles in endothelial cells.

Mostefai HA, Agouni A, Carusio N, Mastronardi ML, Heymes C, Henrion D, Andriantsitohaina R, Martinez MC.

J Immunol. 2008 Apr 1;180(7):5028-35.


Parathyroid hormone-related protein induces cell survival in human renal cell carcinoma through the PI3K Akt pathway: evidence for a critical role for integrin-linked kinase and nuclear factor kappa B.

Agouni A, Sourbier C, Danilin S, Rothhut S, Lindner V, Jacqmin D, Helwig JJ, Lang H, Massfelder T.

Carcinogenesis. 2007 Sep;28(9):1893-901. Epub 2007 Apr 29.


Sonic hedgehog carried by microparticles corrects endothelial injury through nitric oxide release.

Agouni A, Mostefai HA, Porro C, Carusio N, Favre J, Richard V, Henrion D, Martínez MC, Andriantsitohaina R.

FASEB J. 2007 Sep;21(11):2735-41. Epub 2007 Apr 11.


The phosphoinositide 3-kinase/Akt pathway: a new target in human renal cell carcinoma therapy.

Sourbier C, Lindner V, Lang H, Agouni A, Schordan E, Danilin S, Rothhut S, Jacqmin D, Helwig JJ, Massfelder T.

Cancer Res. 2006 May 15;66(10):5130-42.

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