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Items: 1 to 50 of 60

1.

Multivariate analysis and visualization of splicing correlations in single-gene transcriptomes.

Emerick MC, Parmigiani G, Agnew WS.

BMC Bioinformatics. 2007 Jan 18;8:16.

2.
3.

A profile of alternative RNA splicing and transcript variation of CACNA1H, a human T-channel gene candidate for idiopathic generalized epilepsies.

Zhong X, Liu JR, Kyle JW, Hanck DA, Agnew WS.

Hum Mol Genet. 2006 May 1;15(9):1497-512. Epub 2006 Mar 24.

PMID:
16565161
5.

Systematic identification of splice variants in human P/Q-type channel alpha1(2.1) subunits: implications for current density and Ca2+-dependent inactivation.

Soong TW, DeMaria CD, Alvania RS, Zweifel LS, Liang MC, Mittman S, Agnew WS, Yue DT.

J Neurosci. 2002 Dec 1;22(23):10142-52.

6.

Full-length single-gene cDNA libraries: applications in splice variant analysis.

Regan MR, Emerick MC, Agnew WS.

Anal Biochem. 2000 Nov 15;286(2):265-76.

PMID:
11067749
7.
8.

Structure and alternative splicing of the gene encoding alpha1I, a human brain T calcium channel alpha1 subunit.

Mittman S, Guo J, Emerick MC, Agnew WS.

Neurosci Lett. 1999 Jul 16;269(3):121-4.

PMID:
10454147
9.

Mechanism of modulation of the voltage-gated skeletal and cardiac muscle sodium channels by fatty acids.

Bendahhou S, Cummins TR, Agnew WS.

Am J Physiol. 1997 Feb;272(2 Pt 1):C592-600.

PMID:
9124303
10.

The type 1 inositol 1,4,5-trisphosphate receptor gene is altered in the opisthotonos mouse.

Street VA, Bosma MM, Demas VP, Regan MR, Lin DD, Robinson LC, Agnew WS, Tempel BL.

J Neurosci. 1997 Jan 15;17(2):635-45.

11.
12.

Serine-1321-independent regulation of the mu 1 adult skeletal muscle Na+ channel by protein kinase C.

Bendahhou S, Cummins TR, Potts JF, Tong J, Agnew WS.

Proc Natl Acad Sci U S A. 1995 Dec 19;92(26):12003-7.

13.

A simplified method for single-cell RT-PCR that can detect and distinguish genomic DNA and mRNA transcripts.

Tong J, Bendahhou S, Chen H, Agnew WS.

Nucleic Acids Res. 1994 Aug 11;22(15):3253-4. No abstract available.

15.

A glial-specific voltage-sensitive Na channel gene maps close to clustered genes for neuronal isoforms on mouse chromosome 2.

Potts JF, Regan MR, Rochelle JM, Seldin MF, Agnew WS.

Biochem Biophys Res Commun. 1993 Nov 30;197(1):100-4.

PMID:
8250913
16.

A single B1 subunit mapped to mouse chromosome 7 may be a common component of Na channel isoforms from brain, skeletal muscle and heart.

Tong J, Potts JF, Rochelle JM, Seldin MF, Agnew WS.

Biochem Biophys Res Commun. 1993 Sep 15;195(2):679-85.

PMID:
7690558
18.

Functional consequences of a Na+ channel mutation causing hyperkalemic periodic paralysis.

Cummins TR, Zhou J, Sigworth FJ, Ukomadu C, Stephan M, Ptácek LJ, Agnew WS.

Neuron. 1993 Apr;10(4):667-78.

PMID:
8386527
19.

muI Na+ channels expressed transiently in human embryonic kidney cells: biochemical and biophysical properties.

Ukomadu C, Zhou J, Sigworth FJ, Agnew WS.

Neuron. 1992 Apr;8(4):663-76.

PMID:
1314619
20.

Assay and purification of neuronal receptors for inositol 1,4,5-trisphosphate.

Hingorani SR, Agnew WS.

Methods Enzymol. 1992;207:573-91. No abstract available.

PMID:
1326703
21.

Multiple gating modes and the effect of modulating factors on the microI sodium channel.

Zhou JY, Potts JF, Trimmer JS, Agnew WS, Sigworth FJ.

Neuron. 1991 Nov;7(5):775-85.

PMID:
1660285
22.

Paramyotonia congenita and hyperkalemic periodic paralysis map to the same sodium-channel gene locus.

Ptacek LJ, Trimmer JS, Agnew WS, Roberts JW, Petajan JH, Leppert M.

Am J Hum Genet. 1991 Oct;49(4):851-4.

23.

Voltage-sensitive Na+ channels: motifs, modes and modulation.

Stephan M, Agnew WS.

Curr Opin Cell Biol. 1991 Aug;3(4):676-84. Review.

PMID:
1722983
24.

Analysis in a large hyperkalemic periodic paralysis pedigree supports tight linkage to a sodium channel locus.

Ptacek LJ, Tyler F, Trimmer JS, Agnew WS, Leppert M.

Am J Hum Genet. 1991 Aug;49(2):378-82.

25.

A rapid ion-exchange assay for detergent-solubilized inositol 1,4,5-trisphosphate receptors.

Hingorani SR, Agnew WS.

Anal Biochem. 1991 Apr;194(1):204-13.

PMID:
1651064
26.

Voltage-sensitive sodium channels: agents that perturb inactivation gating.

Agnew WS, Cooper EC, Shenkel S, Correa AM, James WM, Ukomadu C, Tomiko SA.

Ann N Y Acad Sci. 1991;625:200-23. Review.

PMID:
1647724
27.

Regulation of muscle sodium channel transcripts during development and in response to denervation.

Trimmer JS, Cooperman SS, Agnew WS, Mandel G.

Dev Biol. 1990 Dec;142(2):360-7.

PMID:
2175278
28.

Voltage activation of purified eel sodium channels reconstituted into artificial liposomes.

Correa AM, Bezanilla F, Agnew WS.

Biochemistry. 1990 Jul 3;29(26):6230-40.

PMID:
2169867
29.

Purified, modified eel sodium channels are active in planar bilayers in the absence of activating neurotoxins.

Shenkel S, Cooper EC, James W, Agnew WS, Sigworth FJ.

Proc Natl Acad Sci U S A. 1989 Dec;86(23):9592-6.

32.

Alpha-(2----8)-polysialic acid immunoreactivity in voltage-sensitive sodium channel of eel electric organ.

James WM, Agnew WS.

Proc R Soc Lond B Biol Sci. 1989 Jul 22;237(1287):233-45.

PMID:
2475874
33.
34.

Excitation-contraction coupling. Cloning of the SR foot.

Agnew WS.

Nature. 1989 Jun 8;339(6224):422-3. No abstract available.

PMID:
2542799
35.

Molecular diversity of voltage-sensitive Na channels.

Trimmer JS, Agnew WS.

Annu Rev Physiol. 1989;51:401-18. Review. No abstract available.

PMID:
2540698
36.
37.

Excitation-contraction coupling. Proteins that bridge the gap.

Agnew WS.

Nature. 1988 Jul 28;334(6180):299-300. No abstract available.

PMID:
2455870
38.

A Rosetta stone for K channels.

Agnew WS.

Nature. 1988 Jan 14;331(6152):114-5. No abstract available.

PMID:
2448634
39.
40.
41.

Dual roles for DHP receptors in excitation--contraction coupling?

Agnew WS.

Nature. 1987 Jul 23-29;328(6128):297. No abstract available.

PMID:
3037386
42.

Hydrodynamic properties of the chromaffin granule hydrogen ion pumping adenosinetriphosphatase.

Dean GE, Nelson PJ, Agnew WS, Rudnick G.

Biochemistry. 1987 Apr 21;26(8):2301-5.

PMID:
2887199
43.

Neurochemistry. Lessons from large molecules.

Agnew WS.

Nature. 1986 Aug 28-Sep 3;322(6082):770-1. No abstract available.

PMID:
2427954
44.
45.

The structure and function of the voltage-sensitive Na channel.

Agnew WS, Tomiko SA, Rosenberg RL, Emerick MC, Cooper EC.

Ann N Y Acad Sci. 1986;479:238-56. No abstract available.

PMID:
2433994
46.

Squalene synthetase.

Agnew WS.

Methods Enzymol. 1985;110:359-73. No abstract available.

PMID:
3894879
47.
49.

Voltage-regulated sodium channel molecules.

Agnew WS.

Annu Rev Physiol. 1984;46:517-30. Review.

PMID:
6324661

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