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Items: 1 to 50 of 584

1.

Adenosine A2A-dopamine D2 receptor-receptor interaction in neurons and astrocytes: Evidence and perspectives.

Guidolin D, Marcoli M, Tortorella C, Maura G, Agnati LF.

Prog Mol Biol Transl Sci. 2020;169:247-277. doi: 10.1016/bs.pmbts.2019.11.004. Epub 2019 Dec 5.

PMID:
31952688
2.

Exosomes From Astrocyte Processes: Signaling to Neurons.

Venturini A, Passalacqua M, Pelassa S, Pastorino F, Tedesco M, Cortese K, Gagliani MC, Leo G, Maura G, Guidolin D, Agnati LF, Marcoli M, Cervetto C.

Front Pharmacol. 2019 Dec 2;10:1452. doi: 10.3389/fphar.2019.01452. eCollection 2019.

3.

A New Integrative Theory of Brain-Body-Ecosystem Medicine: From the Hippocratic Holistic View of Medicine to Our Modern Society.

Guidolin D, Anderlini D, Marcoli M, Cortelli P, Calandra-Buonaura G, Woods AS, Agnati LF.

Int J Environ Res Public Health. 2019 Aug 28;16(17). pii: E3136. doi: 10.3390/ijerph16173136.

4.

From the hierarchical organization of the central nervous system to the hierarchical aspects of biocodes.

Guidolin D, Marcoli M, Tortorella C, Maura G, Agnati LF.

Biosystems. 2019 Sep;183:103975. doi: 10.1016/j.biosystems.2019.103975. Epub 2019 May 22. Review.

PMID:
31128147
5.

A2A-D2 Heteromers on Striatal Astrocytes: Biochemical and Biophysical Evidence.

Pelassa S, Guidolin D, Venturini A, Averna M, Frumento G, Campanini L, Bernardi R, Cortelli P, Buonaura GC, Maura G, Agnati LF, Cervetto C, Marcoli M.

Int J Mol Sci. 2019 May 17;20(10). pii: E2457. doi: 10.3390/ijms20102457.

6.

Receptor-Receptor Interactions as a Widespread Phenomenon: Novel Targets for Drug Development?

Guidolin D, Marcoli M, Tortorella C, Maura G, Agnati LF.

Front Endocrinol (Lausanne). 2019 Feb 18;10:53. doi: 10.3389/fendo.2019.00053. eCollection 2019. Review.

7.

Homocysteine and A2A-D2 Receptor-Receptor Interaction at Striatal Astrocyte Processes.

Cervetto C, Venturini A, Guidolin D, Maura G, Passalacqua M, Tacchetti C, Cortelli P, Genedani S, Candiani S, Ramoino P, Pelassa S, Marcoli M, Agnati LF.

J Mol Neurosci. 2018 Aug;65(4):456-466. doi: 10.1007/s12031-018-1120-4. Epub 2018 Jul 20.

PMID:
30030763
8.

Near-infrared laser photons induce glutamate release from cerebrocortical nerve terminals.

Amaroli A, Marcoli M, Venturini A, Passalacqua M, Agnati LF, Signore A, Raffetto M, Maura G, Benedicenti S, Cervetto C.

J Biophotonics. 2018 Nov;11(11):e201800102. doi: 10.1002/jbio.201800102. Epub 2018 Aug 30.

PMID:
29931754
9.

G protein-coupled receptor-receptor interactions give integrative dynamics to intercellular communication.

Guidolin D, Marcoli M, Tortorella C, Maura G, Agnati LF.

Rev Neurosci. 2018 Sep 25;29(7):703-726. doi: 10.1515/revneuro-2017-0087. Review.

PMID:
29466243
10.

The brain as a "hyper-network": the key role of neural networks as main producers of the integrated brain actions especially via the "broadcasted" neuroconnectomics.

Agnati LF, Marcoli M, Maura G, Woods A, Guidolin D.

J Neural Transm (Vienna). 2018 Jun;125(6):883-897. doi: 10.1007/s00702-018-1855-7. Epub 2018 Feb 9. Review.

PMID:
29427068
11.

Functional roles of three cues that provide nonsynaptic modes of communication in the brain: electromagnetic field, oxygen, and carbon dioxide.

Agnati LF, Guidolin D, Maura G, Marcoli M.

J Neurophysiol. 2018 Jan 1;119(1):356-368. doi: 10.1152/jn.00413.2017. Epub 2017 Oct 25. Review.

12.

Homeostasis and the concept of 'interstitial fluids hierarchy': Relevance of cerebrospinal fluid sodium concentrations and brain temperature control (Review).

Agnati LF, Marcoli M, Leo G, Maura G, Guidolin D.

Int J Mol Med. 2017 Mar;39(3):487-497. doi: 10.3892/ijmm.2017.2874. Epub 2017 Feb 3. Review.

13.

New dimensions of connectomics and network plasticity in the central nervous system.

Guidolin D, Marcoli M, Maura G, Agnati LF.

Rev Neurosci. 2017 Feb 1;28(2):113-132. doi: 10.1515/revneuro-2016-0051. Review.

PMID:
28030363
14.

A2A-D2 receptor-receptor interaction modulates gliotransmitter release from striatal astrocyte processes.

Cervetto C, Venturini A, Passalacqua M, Guidolin D, Genedani S, Fuxe K, Borroto-Esquela DO, Cortelli P, Woods A, Maura G, Marcoli M, Agnati LF.

J Neurochem. 2017 Jan;140(2):268-279. doi: 10.1111/jnc.13885. Epub 2016 Nov 29.

15.

Understanding the Functional Plasticity in Neural Networks of the Basal Ganglia in Cocaine Use Disorder: A Role for Allosteric Receptor-Receptor Interactions in A2A-D2 Heteroreceptor Complexes.

Borroto-Escuela DO, Wydra K, Pintsuk J, Narvaez M, Corrales F, Zaniewska M, Agnati LF, Franco R, Tanganelli S, Ferraro L, Filip M, Fuxe K.

Neural Plast. 2016;2016:4827268. Epub 2016 Oct 30. Review.

16.

Neuroglobin, a Factor Playing for Nerve Cell Survival.

Guidolin D, Tortorella C, Marcoli M, Maura G, Agnati LF.

Int J Mol Sci. 2016 Oct 31;17(11). pii: E1817. Review.

17.

The multi-facet aspects of cell sentience and their relevance for the integrative brain actions: role of membrane protein energy landscape.

Agnati LF, Marcoli M, Maura G, Fuxe K, Guidolin D.

Rev Neurosci. 2016 Jun 1;27(4):347-63. doi: 10.1515/revneuro-2015-0049. Review.

PMID:
26751866
18.

Role of iso-receptors in receptor-receptor interactions with a focus on dopamine iso-receptor complexes.

Agnati LF, Guidolin D, Cervetto C, Borroto-Escuela DO, Fuxe K.

Rev Neurosci. 2016 Jan;27(1):1-25. doi: 10.1515/revneuro-2015-0024. Review.

PMID:
26418645
19.

Calcium-permeable AMPA receptors trigger vesicular glutamate release from Bergmann gliosomes.

Cervetto C, Frattaroli D, Venturini A, Passalacqua M, Nobile M, Alloisio S, Tacchetti C, Maura G, Agnati LF, Marcoli M.

Neuropharmacology. 2015 Dec;99:396-407. doi: 10.1016/j.neuropharm.2015.08.011. Epub 2015 Aug 7.

PMID:
26260232
20.

On the role of the extracellular space on the holistic behavior of the brain.

Marcoli M, Agnati LF, Benedetti F, Genedani S, Guidolin D, Ferraro L, Maura G, Fuxe K.

Rev Neurosci. 2015;26(5):489-506. doi: 10.1515/revneuro-2015-0007. Review.

PMID:
26103627
21.

The role of transmitter diffusion and flow versus extracellular vesicles in volume transmission in the brain neural-glial networks.

Borroto-Escuela DO, Agnati LF, Bechter K, Jansson A, Tarakanov AO, Fuxe K.

Philos Trans R Soc Lond B Biol Sci. 2015 Jul 5;370(1672). pii: 20140183. doi: 10.1098/rstb.2014.0183. Review.

22.

Enhancement of the FGFR1 signaling in the FGFR1-5-HT1A heteroreceptor complex in midbrain raphe 5-HT neuron systems. Relevance for neuroplasticity and depression.

Borroto-Escuela DO, Pérez-Alea M, Narvaez M, Tarakanov AO, Mudó G, Jiménez-Beristain A, Agnati LF, Ciruela F, Belluardo N, Fuxe K.

Biochem Biophys Res Commun. 2015 Jul 31;463(3):180-6. doi: 10.1016/j.bbrc.2015.04.133. Epub 2015 May 6.

PMID:
25957476
23.

Volume Transmission in Central Dopamine and Noradrenaline Neurons and Its Astroglial Targets.

Fuxe K, Agnati LF, Marcoli M, Borroto-Escuela DO.

Neurochem Res. 2015 Dec;40(12):2600-14. doi: 10.1007/s11064-015-1574-5. Epub 2015 Apr 17. Review.

PMID:
25894681
24.

Acute isoproterenol induces anxiety-like behavior in rats and increases plasma content of extracellular vesicles.

Leo G, Guescini M, Genedani S, Stocchi V, Carone C, Filaferro M, Sisti D, Marcoli M, Maura G, Cortelli P, Guidolin D, Fuxe K, Agnati LF.

Physiol Behav. 2015 Apr 1;142:79-84. doi: 10.1016/j.physbeh.2015.02.002. Epub 2015 Feb 2. Erratum in: Physiol Behav. 2015 May 1;143:169.

PMID:
25654993
25.

Dopamine heteroreceptor complexes as therapeutic targets in Parkinson's disease.

Fuxe K, Guidolin D, Agnati LF, Borroto-Escuela DO.

Expert Opin Ther Targets. 2015 Mar;19(3):377-98. doi: 10.1517/14728222.2014.981529. Epub 2014 Dec 8. Review.

PMID:
25486101
26.

Evidence for the existence of FGFR1-5-HT1A heteroreceptor complexes in the midbrain raphe 5-HT system.

Borroto-Escuela DO, Narvaez M, Pérez-Alea M, Tarakanov AO, Jiménez-Beristain A, Mudó G, Agnati LF, Ciruela F, Belluardo N, Fuxe K.

Biochem Biophys Res Commun. 2015 Jan 2;456(1):489-93. doi: 10.1016/j.bbrc.2014.11.112. Epub 2014 Dec 6.

PMID:
25485703
27.

G-protein-coupled receptor type A heteromers as an emerging therapeutic target.

Guidolin D, Agnati LF, Marcoli M, Borroto-Escuela DO, Fuxe K.

Expert Opin Ther Targets. 2015 Feb;19(2):265-83. doi: 10.1517/14728222.2014.981155. Epub 2014 Nov 10. Review.

PMID:
25381716
28.

Dopamine D1 and D2 receptor immunoreactivities in the arcuate-median eminence complex and their link to the tubero-infundibular dopamine neurons.

Romero-Fernandez W, Borroto-Escuela DO, Vargas-Barroso V, Narváez M, Di Palma M, Agnati LF, Larriva Sahd J, Fuxe K.

Eur J Histochem. 2014 Jul 18;58(3):2400. doi: 10.4081/ejh.2014.2400.

29.

Understanding the role of heteroreceptor complexes in the central nervous system.

Fuxe K, Borroto-Escuela D, Fisone G, Agnati LF, Tanganelli S.

Curr Protein Pept Sci. 2014;15(7):647.

PMID:
25256022
30.

Adenosine A2A-D2 receptor-receptor interactions in putative heteromers in the regulation of the striato-pallidal gaba pathway: possible relevance for parkinson's disease and its treatment.

Beggiato S, Antonelli T, Tomasini MC, Borelli AC, Agnati LF, Tanganelli S, Fuxe K, Ferraro L.

Curr Protein Pept Sci. 2014;15(7):673-80. Review.

PMID:
25175458
31.

Neurotensin NTS1-dopamine D2 receptor-receptor interactions in putative receptor heteromers: relevance for Parkinson's disease and schizophrenia.

Ferraro L, Beggiato S, Borroto-Escuela DO, Ravani L, O'Connor WT, Tomasini MC, Borelli AC, Agnati LF, Antonelli T, Tanganelli S, Fuxe K.

Curr Protein Pept Sci. 2014;15(7):681-90. Review.

PMID:
25175457
32.

"Neuro-semeiotics" and "free-energy minimization" suggest a unified perspective for integrative brain actions: focus on receptor heteromers and Roamer type of volume transmission.

Agnati LF, Guidolin D, Marcoli M, Genedani S, Borroto-Escuela D, Maura G, Fuxe K.

Curr Protein Pept Sci. 2014;15(7):703-18.

PMID:
25175453
33.

Preferential activation by galanin 1-15 fragment of the GalR1 protomer of a GalR1-GalR2 heteroreceptor complex.

Borroto-Escuela DO, Narvaez M, Di Palma M, Calvo F, Rodriguez D, Millon C, Carlsson J, Agnati LF, Garriga P, Díaz-Cabiale Z, Fuxe K.

Biochem Biophys Res Commun. 2014 Sep 26;452(3):347-53. doi: 10.1016/j.bbrc.2014.08.061. Epub 2014 Aug 22.

PMID:
25152404
34.

Extracellular-vesicle type of volume transmission and tunnelling-nanotube type of wiring transmission add a new dimension to brain neuro-glial networks.

Agnati LF, Fuxe K.

Philos Trans R Soc Lond B Biol Sci. 2014 Sep 26;369(1652). pii: 20130505. doi: 10.1098/rstb.2013.0505. Review.

35.

In vitro effects of cocaine on tunneling nanotube formation and extracellular vesicle release in glioblastoma cell cultures.

Carone C, Genedani S, Leo G, Filaferro M, Fuxe K, Agnati LF.

J Mol Neurosci. 2015 Jan;55(1):42-50. doi: 10.1007/s12031-014-0365-9. Epub 2014 Jul 5.

PMID:
24996625
36.

Dopamine D2 heteroreceptor complexes and their receptor-receptor interactions in ventral striatum: novel targets for antipsychotic drugs.

Fuxe K, Borroto-Escuela DO, Tarakanov AO, Romero-Fernandez W, Ferraro L, Tanganelli S, Perez-Alea M, Di Palma M, Agnati LF.

Prog Brain Res. 2014;211:113-39. doi: 10.1016/B978-0-444-63425-2.00005-2. Review.

PMID:
24968778
37.

The impact of receptor-receptor interactions in heteroreceptor complexes on brain plasticity.

Fuxe K, Agnati LF, Borroto-Escuela DO.

Expert Rev Neurother. 2014 Jul;14(7):719-21. doi: 10.1586/14737175.2014.922878. Epub 2014 Jun 4.

PMID:
24894440
38.

Information handling by the brain: proposal of a new "paradigm" involving the roamer type of volume transmission and the tunneling nanotube type of wiring transmission.

Agnati LF, Guidolin D, Maura G, Marcoli M, Leo G, Carone C, De Caro R, Genedani S, Borroto-Escuela DO, Fuxe K.

J Neural Transm (Vienna). 2014 Dec;121(12):1431-49. doi: 10.1007/s00702-014-1240-0. Epub 2014 May 28. Review.

PMID:
24866694
39.

Diversity and Bias through Receptor-Receptor Interactions in GPCR Heteroreceptor Complexes. Focus on Examples from Dopamine D2 Receptor Heteromerization.

Fuxe K, Tarakanov A, Romero Fernandez W, Ferraro L, Tanganelli S, Filip M, Agnati LF, Garriga P, Diaz-Cabiale Z, Borroto-Escuela DO.

Front Endocrinol (Lausanne). 2014 May 13;5:71. doi: 10.3389/fendo.2014.00071. eCollection 2014. Review.

40.

The G protein-coupled receptor heterodimer network (GPCR-HetNet) and its hub components.

Borroto-Escuela DO, Brito I, Romero-Fernandez W, Di Palma M, Oflijan J, Skieterska K, Duchou J, Van Craenenbroeck K, Suárez-Boomgaard D, Rivera A, Guidolin D, Agnati LF, Fuxe K.

Int J Mol Sci. 2014 May 14;15(5):8570-90. doi: 10.3390/ijms15058570.

41.

Hallucinogenic 5-HT2AR agonists LSD and DOI enhance dopamine D2R protomer recognition and signaling of D2-5-HT2A heteroreceptor complexes.

Borroto-Escuela DO, Romero-Fernandez W, Narvaez M, Oflijan J, Agnati LF, Fuxe K.

Biochem Biophys Res Commun. 2014 Jan 3;443(1):278-84. doi: 10.1016/j.bbrc.2013.11.104. Epub 2013 Dec 2.

PMID:
24309097
42.

Neuroglobin as a regulator of mitochondrial-dependent apoptosis: a bioinformatics analysis.

Guidolin D, Agnati LF, Tortorella C, Marcoli M, Maura G, Albertin G, Fuxe K.

Int J Mol Med. 2014 Jan;33(1):111-6. doi: 10.3892/ijmm.2013.1564. Epub 2013 Nov 21.

PMID:
24270633
43.

Dynamic modulation of FGFR1-5-HT1A heteroreceptor complexes. Agonist treatment enhances participation of FGFR1 and 5-HT1A homodimers and recruitment of β-arrestin2.

Borroto-Escuela DO, Corrales F, Narvaez M, Oflijan J, Agnati LF, Palkovits M, Fuxe K.

Biochem Biophys Res Commun. 2013 Nov 15;441(2):387-92. doi: 10.1016/j.bbrc.2013.10.067. Epub 2013 Oct 21.

PMID:
24157794
44.

Bioluminescence resonance energy transfer methods to study G protein-coupled receptor-receptor tyrosine kinase heteroreceptor complexes.

Borroto-Escuela DO, Flajolet M, Agnati LF, Greengard P, Fuxe K.

Methods Cell Biol. 2013;117:141-64. doi: 10.1016/B978-0-12-408143-7.00008-6.

45.

Moonlighting proteins and protein-protein interactions as neurotherapeutic targets in the G protein-coupled receptor field.

Fuxe K, Borroto-Escuela DO, Romero-Fernandez W, Palkovits M, Tarakanov AO, Ciruela F, Agnati LF.

Neuropsychopharmacology. 2014 Jan;39(1):131-55. doi: 10.1038/npp.2013.242. Epub 2013 Sep 6. Review.

46.

On the g-protein-coupled receptor heteromers and their allosteric receptor-receptor interactions in the central nervous system: focus on their role in pain modulation.

Borroto-Escuela DO, Romero-Fernandez W, Rivera A, Van Craenenbroeck K, Tarakanov AO, Agnati LF, Fuxe K.

Evid Based Complement Alternat Med. 2013;2013:563716. doi: 10.1155/2013/563716. Epub 2013 Jul 17.

47.

The neurobiology of imagination: possible role of interaction-dominant dynamics and default mode network.

Agnati LF, Guidolin D, Battistin L, Pagnoni G, Fuxe K.

Front Psychol. 2013 May 24;4:296. doi: 10.3389/fpsyg.2013.00296. eCollection 2013.

48.

Volume transmission and its different forms in the central nervous system.

Fuxe K, Borroto-Escuela DO, Romero-Fernandez W, Zhang WB, Agnati LF.

Chin J Integr Med. 2013 May;19(5):323-9. doi: 10.1007/s11655-013-1455-1. Epub 2013 May 15. Review.

PMID:
23674109
49.

Dopamine D2 receptor signaling dynamics of dopamine D2-neurotensin 1 receptor heteromers.

Borroto-Escuela DO, Ravani A, Tarakanov AO, Brito I, Narvaez M, Romero-Fernandez W, Corrales F, Agnati LF, Tanganelli S, Ferraro L, Fuxe K.

Biochem Biophys Res Commun. 2013 May 24;435(1):140-6. doi: 10.1016/j.bbrc.2013.04.058. Epub 2013 Apr 25.

PMID:
23624386
50.

A new interpretative paradigm for Conformational Protein Diseases.

Agnati LF, Guidolin D, Woods AS, Ciruela F, Carone C, Vallelunga A, Escuela DO, Genedani S, Fuxe K.

Curr Protein Pept Sci. 2013 Mar;14(2):141-60. Review.

PMID:
23441893

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