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Items: 41

1.
2.

Characterization of the Preclinical Pharmacology of the New 2-Aminomethylphenol, JPC-3210, for Malaria Treatment and Prevention.

Birrell GW, Heffernan GD, Schiehser GA, Anderson J, Ager AL, Morales P, MacKenzie D, van Breda K, Chavchich M, Jacobus LR, Shanks GD, Jacobus DP, Edstein MD.

Antimicrob Agents Chemother. 2018 Mar 27;62(4). pii: e01335-17. doi: 10.1128/AAC.01335-17. Print 2018 Apr.

3.

Shoulder proprioception: How is it measured and is it reliable? A systematic review.

Ager AL, Roy JS, Roos M, Belley AF, Cools A, Hébert LJ.

J Hand Ther. 2017 Apr - Jun;30(2):221-231. doi: 10.1016/j.jht.2017.05.003. Review.

PMID:
28641738
4.

Electromyographic analysis of rotator cuff muscles in patients with rotator cuff tendinopathy: A systematic review.

de Oliveira FCL, Bouyer LJ, Ager AL, Roy JS.

J Electromyogr Kinesiol. 2017 Aug;35:100-114. doi: 10.1016/j.jelekin.2017.06.002. Epub 2017 Jun 10. Review.

PMID:
28641171
5.

Lead Selection of a New Aminomethylphenol, JPC-3210, for Malaria Treatment and Prevention.

Chavchich M, Birrell GW, Ager AL, MacKenzie DO, Heffernan GD, Schiehser GA, Jacobus LR, Shanks GD, Jacobus DP, Edstein MD.

Antimicrob Agents Chemother. 2016 Apr 22;60(5):3115-8. doi: 10.1128/AAC.03066-15. Print 2016 May.

6.

JPC-2997, a new aminomethylphenol with high in vitro and in vivo antimalarial activities against blood stages of Plasmodium.

Birrell GW, Chavchich M, Ager AL, Shieh HM, Heffernan GD, Zhao W, Krasucki PE, Saionz KW, Terpinski J, Schiehser GA, Jacobus LR, Shanks GD, Jacobus DP, Edstein MD.

Antimicrob Agents Chemother. 2015 Jan;59(1):170-7. doi: 10.1128/AAC.03762-14. Epub 2014 Oct 20.

7.

A targeted and adjuvanted nanocarrier lowers the effective dose of liposomal amphotericin B and enhances adaptive immunity in murine cutaneous leishmaniasis.

Daftarian PM, Stone GW, Kovalski L, Kumar M, Vosoughi A, Urbieta M, Blackwelder P, Dikici E, Serafini P, Duffort S, Boodoo R, Rodríguez-Cortés A, Lemmon V, Deo S, Alberola J, Perez VL, Daunert S, Ager AL.

J Infect Dis. 2013 Dec 1;208(11):1914-22. doi: 10.1093/infdis/jit378. Epub 2013 Jul 29.

8.

Novel diaryl ureas with efficacy in a mouse model of malaria.

Anderson JW, Sarantakis D, Terpinski J, Kumar TR, Tsai HC, Kuo M, Ager AL, Jacobs WR Jr, Schiehser GA, Ekins S, Sacchettini JC, Jacobus DP, Fidock DA, Freundlich JS.

Bioorg Med Chem Lett. 2013 Feb 15;23(4):1022-5. doi: 10.1016/j.bmcl.2012.12.022. Epub 2012 Dec 20.

9.

Antiparasitic activities and toxicities of individual enantiomers of the 8-aminoquinoline 8-[(4-amino-1-methylbutyl)amino]-6-methoxy-4-methyl-5-[3,4-dichlorophenoxy]quinoline succinate.

Nanayakkara NP, Ager AL Jr, Bartlett MS, Yardley V, Croft SL, Khan IA, McChesney JD, Walker LA.

Antimicrob Agents Chemother. 2008 Jun;52(6):2130-7. doi: 10.1128/AAC.00645-07. Epub 2008 Mar 31.

10.

Antimalarial pharmacodynamics and pharmacokinetics of a third-generation antifolate--JPC2056--in cynomolgus monkeys using an in vivo in vitro model.

Edstein MD, Kotecka BM, Ager AL, Smith KS, DiTusa CA, Diaz DS, Kyle DE, Schiehser GA, Jacobus DP, Rieckmann KH, O'Neil MT.

J Antimicrob Chemother. 2007 Oct;60(4):811-8. Epub 2007 Jul 23.

PMID:
17646199
11.

Intestinal parasites among young children in the interior of Guyana.

Lindo JF, Validum L, Ager AL, Campa A, Cuadrado RR, Cummings R, Palmer CJ.

West Indian Med J. 2002 Mar;51(1):25-7.

PMID:
12089870
12.

Phenoxypropoxybiguanides, prodrugs of DHFR-inhibiting diaminotriazine antimalarials.

Jensen NP, Ager AL, Bliss RA, Canfield CJ, Kotecka BM, Rieckmann KH, Terpinski J, Jacobus DP.

J Med Chem. 2001 Nov 8;44(23):3925-31.

PMID:
11689078
13.

Assessment of the antimalarial potential of tetraoxane WR 148999.

Vennerstrom JL, Ager AL Jr, Andersen SL, Grace JM, Wongpanich V, Angerhofer CK, Hu JK, Wesche DL.

Am J Trop Med Hyg. 2000 May;62(5):573-8.

PMID:
11289666
14.

Synthesis and antimalarial activity of sixteen dispiro-1,2,4, 5-tetraoxanes: alkyl-substituted 7,8,15,16-tetraoxadispiro[5.2.5. 2]hexadecanes.

Vennerstrom JL, Dong Y, Andersen SL, Ager AL Jr, Fu H, Miller RE, Wesche DL, Kyle DE, Gerena L, Walters SM, Wood JK, Edwards G, Holme AD, McLean WG, Milhous WK.

J Med Chem. 2000 Jul 13;43(14):2753-8.

PMID:
10893313
15.

Dengue in Guyana.

Palmer CJ, Validum L, Vorndam VA, Clark GG, Validum C, Cummings R, Lindo JF, Ager AL, Cuadrado RR.

Lancet. 1999 Jul 24;354(9175):304.

PMID:
10440312
16.
17.

Bisquinolines. 2. Antimalarial N,N-bis(7-chloroquinolin-4-yl)heteroalkanediamines.

Vennerstrom JL, Ager AL Jr, Dorn A, Andersen SL, Gerena L, Ridley RG, Milhous WK.

J Med Chem. 1998 Oct 22;41(22):4360-4.

PMID:
9784111
18.

Increased prevalence of Plasmodium falciparum malaria in Honduras, Central America.

Palmer CJ, Makler M, Klaskala WI, Lindo JF, Baum MK, Ager AL.

Rev Panam Salud Publica. 1998 Jul;4(1):40-2.

PMID:
9734227
19.

A review of practical techniques for the diagnosis of malaria.

Makler MT, Palmer CJ, Ager AL.

Ann Trop Med Parasitol. 1998 Jun;92(4):419-33. Review.

PMID:
9683894
20.

Intestinal parasitic infections in human immunodeficiency virus (HIV)-positive and HIV-negative individuals in San Pedro Sula, Honduras.

Lindo JF, Dubon JM, Ager AL, de Gourville EM, Solo-Gabriele H, Klaskala WI, Baum MK, Palmer CJ.

Am J Trop Med Hyg. 1998 Apr;58(4):431-5.

PMID:
9574787
21.

Evaluation of the OptiMAL test for rapid diagnosis of Plasmodium vivax and Plasmodium falciparum malaria.

Palmer CJ, Lindo JF, Klaskala WI, Quesada JA, Kaminsky R, Baum MK, Ager AL.

J Clin Microbiol. 1998 Jan;36(1):203-6.

22.

Emergence of multiple drug-resistant Vibrio cholerae O1 in San Pedro Sula, Honduras.

Dubon JM, Palmer CJ, Ager AL, Shor-Posner G, Baum MK.

Lancet. 1997 Mar 29;349(9056):924. No abstract available.

PMID:
9093259
23.

Vitamin E and selenium: contrasting and interacting nutritional determinants of host resistance to parasitic and viral infections.

Levander OA, Ager AL Jr, Beck MA.

Proc Nutr Soc. 1995 Jul;54(2):475-87. Review. No abstract available.

PMID:
8524894
24.

Protection against murine cerebral malaria by dietary-induced oxidative stress.

Levander OA, Fontela R, Morris VC, Ager AL Jr.

J Parasitol. 1995 Feb;81(1):99-103.

PMID:
7876987
25.

Efficacy of azithromycin as a causal prophylactic agent against murine malaria.

Andersen SL, Ager AL, McGreevy P, Schuster BG, Ellis W, Berman J.

Antimicrob Agents Chemother. 1994 Aug;38(8):1862-3.

26.

Antimalarial activity of dihydroartemisinin derivatives by transdermal application.

Lin AJ, Ager AL Jr, Klayman DL.

Am J Trop Med Hyg. 1994 Jun;50(6):777-83.

PMID:
8024074
27.

New, antimalarial, tricyclic 1,2,4-trioxanes: evaluations in mice and monkeys.

Posner GH, Oh CH, Webster HK, Ager AL Jr, Rossan RN.

Am J Trop Med Hyg. 1994 Apr;50(4):522-6.

PMID:
8166360
28.

PS-15: a potent, orally active antimalarial from a new class of folic acid antagonists.

Canfield CJ, Milhous WK, Ager AL, Rossan RN, Sweeney TR, Lewis NJ, Jacobus DP.

Am J Trop Med Hyg. 1993 Jul;49(1):121-6.

PMID:
8352384
29.

Comparison of beta-artemether and beta-arteether against malaria parasites in vitro and in vivo.

Shmuklarsky MJ, Klayman DL, Milhous WK, Kyle DE, Rossan RN, Ager AL Jr, Tang DB, Heiffer MH, Canfield CJ, Schuster BG.

Am J Trop Med Hyg. 1993 Mar;48(3):377-84.

PMID:
8470775
30.

Malarial parasites and antioxidant nutrients.

Levander OA, Ager AL Jr.

Parasitology. 1993;107 Suppl:S95-106. Review.

PMID:
8115190
31.

Dispiro-1,2,4,5-tetraoxanes: a new class of antimalarial peroxides.

Vennerstrom JL, Fu HN, Ellis WY, Ager AL Jr, Wood JK, Andersen SL, Gerena L, Milhous WK.

J Med Chem. 1992 Aug 7;35(16):3023-7.

PMID:
1501229
32.

Bisquinolines. 1. N,N-bis(7-chloroquinolin-4-yl)alkanediamines with potential against chloroquine-resistant malaria.

Vennerstrom JL, Ellis WY, Ager AL Jr, Andersen SL, Gerena L, Milhous WK.

J Med Chem. 1992 May 29;35(11):2129-34.

PMID:
1597862
33.

Transdermal artelinic acid: an effective treatment for Plasmodium berghei-infected mice.

Klayman DL, Ager AL Jr, Fleckenstein L, Lin AJ.

Am J Trop Med Hyg. 1991 Nov;45(5):602-7.

PMID:
1951870
34.

Evaluation of Army field sanitation during Blazing Trails '87.

Laubach HE, Barkin JS, Ager AL, Gilcrease WC, Ratkey BP, Silverman MA.

Mil Med. 1990 Dec;155(12):604-6; discussion 623.

PMID:
2125342
35.
36.

Cationic antiprotozoal drugs. Trypanocidal activity of 2-(4'-formylphenyl)imidazo[1,2-a]pyridinium guanylhydrazones and related derivatives of quaternary heteroaromatic compounds.

Sundberg RJ, Dahlhausen DJ, Manikumar G, Mavunkel B, Biswas A, Srinivasan V, Musallam HA, Reid WA Jr, Ager AL.

J Med Chem. 1990 Jan;33(1):298-307.

PMID:
2296025
37.

Menhaden-fish oil in a vitamin E-deficient diet: protection against chloroquine-resistant malaria in mice.

Levander OA, Ager AL Jr, Morris VC, May RG.

Am J Clin Nutr. 1989 Dec;50(6):1237-9.

PMID:
2688393
38.
39.

New tissue schizontocidal antimalarial drugs.

Davidson DE Jr, Ager AL, Brown JL, Chapple FE, Whitmire RE, Rossan RN.

Bull World Health Organ. 1981;59(3):463-79.

40.
41.

Plasmodium berghei: combining folic acid antagonists for potentiation against malaria infections in mice.

Kinnamon KE, Ager AL, Orchard RW.

Exp Parasitol. 1976 Aug;40(1):95-102. No abstract available.

PMID:
780121

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