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Items: 1 to 50 of 64

1.

The role of various transporters in the placental uptake of ofloxacin in an in vitro model of human villous trophoblasts.

Polachek H, Debotton N, Feinshtein V, Rubin M, Ben-Zvi Z, Holcberg G, Agbaria R, Dahan A.

Drug Des Devel Ther. 2018 Dec 4;12:4129-4138. doi: 10.2147/DDDT.S181493. eCollection 2018.

2.

Medical ethics in Israel-bridging religious and secular values.

Jotkowitz AB, Agbaria R, Glick SM.

Lancet. 2017 Jun 24;389(10088):2584-2586. doi: 10.1016/S0140-6736(17)30700-6. Epub 2017 May 8. No abstract available.

PMID:
28495111
3.
4.

Anticancer activity of Nigella sativa (black seed) and its relationship with the thermal processing and quinone composition of the seed.

Agbaria R, Gabarin A, Dahan A, Ben-Shabat S.

Drug Des Devel Ther. 2015 Jun 18;9:3119-24. doi: 10.2147/DDDT.S82938. eCollection 2015.

5.

The use of captisol (SBE7-β-CD) in oral solubility-enabling formulations: Comparison to HPβCD and the solubility-permeability interplay.

Beig A, Agbaria R, Dahan A.

Eur J Pharm Sci. 2015 Sep 18;77:73-8. doi: 10.1016/j.ejps.2015.05.024. Epub 2015 May 22.

PMID:
26006306
6.

Head-To-Head Comparison of Different Solubility-Enabling Formulations of Etoposide and Their Consequent Solubility-Permeability Interplay.

Beig A, Miller JM, Lindley D, Carr RA, Zocharski P, Agbaria R, Dahan A.

J Pharm Sci. 2015 Sep;104(9):2941-7. doi: 10.1002/jps.24496. Epub 2015 May 18.

PMID:
25989509
7.

The biopharmaceutics of successful controlled release drug product: Segmental-dependent permeability of glipizide vs. metoprolol throughout the intestinal tract.

Zur M, Cohen N, Agbaria R, Dahan A.

Int J Pharm. 2015 Jul 15;489(1-2):304-10. doi: 10.1016/j.ijpharm.2015.05.002. Epub 2015 May 6.

PMID:
25957705
8.

Provisional in-silico biopharmaceutics classification (BCS) to guide oral drug product development.

Wolk O, Agbaria R, Dahan A.

Drug Des Devel Ther. 2014 Sep 24;8:1563-75. doi: 10.2147/DDDT.S68909. eCollection 2014.

9.

Oral delivery of lipophilic drugs: the tradeoff between solubility increase and permeability decrease when using cyclodextrin-based formulations.

Beig A, Agbaria R, Dahan A.

PLoS One. 2013 Jul 16;8(7):e68237. doi: 10.1371/journal.pone.0068237. Print 2013. Erratum in: PLoS One. 2013;8(10). doi:8(10): 10.1371/annotation/10ae05dc-90cb-46f1-aa2b-e63eb4a132e2.

10.

The twofold advantage of the amorphous form as an oral drug delivery practice for lipophilic compounds: increased apparent solubility and drug flux through the intestinal membrane.

Dahan A, Beig A, Ioffe-Dahan V, Agbaria R, Miller JM.

AAPS J. 2013 Apr;15(2):347-53. doi: 10.1208/s12248-012-9445-3. Epub 2012 Dec 15.

11.

Targeted prodrugs in oral drug delivery: the modern molecular biopharmaceutical approach.

Dahan A, Khamis M, Agbaria R, Karaman R.

Expert Opin Drug Deliv. 2012 Aug;9(8):1001-13. doi: 10.1517/17425247.2012.697055. Epub 2012 Jun 18. Review.

PMID:
22703376
12.

Inhibition of TNFα-induced iNOS expression in HSV-tk transduced 9L glioblastoma cell lines by Marasmius oreades substances through NF-κB- and MAPK-dependent mechanisms.

Ruimi N, Petrova RD, Agbaria R, Sussan S, Wasser SP, Reznick AZ, Mahajna J.

Mol Biol Rep. 2010 Dec;37(8):3801-12. doi: 10.1007/s11033-010-0035-0. Epub 2010 Mar 12.

PMID:
20224909
13.

Fluorescence of zirconium-naphthalene complexes: effect of ortho-naphthalene substitution.

Rodríguez-Cáceres MI, Agbaria RA, Luna UJ, White S, Warner IM.

Spectrochim Acta A Mol Biomol Spectrosc. 2008 Dec 1;71(3):907-14. doi: 10.1016/j.saa.2008.02.011. Epub 2008 Feb 13.

PMID:
18356097
14.

Tomato lycopene extract supplementation decreases insulin-like growth factor-I levels in colon cancer patients.

Walfisch S, Walfisch Y, Kirilov E, Linde N, Mnitentag H, Agbaria R, Sharoni Y, Levy J.

Eur J Cancer Prev. 2007 Aug;16(4):298-303.

PMID:
17554202
15.

Sculpting the bicyclo[3.1.0]hexane template of carbocyclic nucleosides to improve recognition by herpes thymidine kinase.

Comin MJ, Agbaria R, Ben-Kasus T, Huleihel M, Liao C, Sun G, Nicklaus MC, Deschamps JR, Parrish DA, Marquez VE.

J Am Chem Soc. 2007 May 16;129(19):6216-22. Epub 2007 Apr 24.

PMID:
17451242
16.

The involvement of nuclear factor-kappa B in cyclooxygenase-2 overexpression in murine colon cancer cells transduced with herpes simplex virus thymidine kinase gene.

Konson A, Mahajna JA, Danon A, Rimon G, Agbaria R.

Cancer Gene Ther. 2006 Dec;13(12):1093-104. Epub 2006 Jul 14.

PMID:
16841079
17.

The history of N-methanocarbathymidine: the investigation of a conformational concept leads to the discovery of a potent and selective nucleoside antiviral agent.

Marquez VE, Hughes SH, Sei S, Agbaria R.

Antiviral Res. 2006 Sep;71(2-3):268-75. Epub 2006 May 6. Review.

PMID:
16730077
18.

Entrapment of retroviral vector producer cells in three-dimensional alginate scaffolds for potential use in cancer gene therapy.

Dvir-Ginzberg M, Konson A, Cohen S, Agbaria R.

J Biomed Mater Res B Appl Biomater. 2007 Jan;80(1):59-66.

PMID:
16680730
19.

Zebularine: a unique molecule for an epigenetically based strategy in cancer chemotherapy.

Marquez VE, Kelley JA, Agbaria R, Ben-Kasus T, Cheng JC, Yoo CB, Jones PA.

Ann N Y Acad Sci. 2005 Nov;1058:246-54. Review.

PMID:
16394141
20.

Potent antiviral activity of north-methanocarbathymidine against Kaposi's sarcoma-associated herpesvirus.

Zhu W, Burnette A, Dorjsuren D, Roberts PE, Huleihel M, Shoemaker RH, Marquez VE, Agbaria R, Sei S.

Antimicrob Agents Chemother. 2005 Dec;49(12):4965-73.

21.

Understanding how the herpes thymidine kinase orchestrates optimal sugar and nucleobase conformations to accommodate its substrate at the active site: a chemical approach.

Marquez VE, Choi Y, Comin MJ, Russ P, George C, Huleihel M, Ben-Kasus T, Agbaria R.

J Am Chem Soc. 2005 Nov 2;127(43):15145-50.

PMID:
16248655
22.

Zebularine: a unique molecule for an epigenetically based strategy in cancer chemotherapy. The magic of its chemistry and biology.

Marquez VE, Barchi JJ Jr, Kelley JA, Rao KV, Agbaria R, Ben-Kasus T, Cheng JC, Yoo CB, Jones PA.

Nucleosides Nucleotides Nucleic Acids. 2005;24(5-7):305-18. Review.

PMID:
16247946
23.

Metabolic activation of zebularine, a novel DNA methylation inhibitor, in human bladder carcinoma cells.

Ben-Kasus T, Ben-Zvi Z, Marquez VE, Kelley JA, Agbaria R.

Biochem Pharmacol. 2005 Jul 1;70(1):121-33.

PMID:
15885659
24.

Fluorescence of metal-ligand complexes of mono- and di-substituted naphthalene derivatives.

Rodríguez-Cáceres MI, Agbaria RA, Warner IM.

J Fluoresc. 2005 Mar;15(2):185-90.

PMID:
15883774
25.

Dynamics of the antiviral activity of N-methanocarbathymidine against herpes simplex virus type 1 in cell culture.

Huleihel M, Talishanisky M, Ford H Jr, Marquez VE, Kelley JA, Johns DG, Agbaria R.

Int J Antimicrob Agents. 2005 May;25(5):427-32.

PMID:
15848299
26.

Investigation of the stability of polyelectrolyte multilayer coatings in open-tubular capillary electrochromatography using laser scanning confocal microscopy.

Kapnissi-Christodoulou CP, Lowry M, Agbaria RA, Geng L, Warner IM.

Electrophoresis. 2005 Feb;26(4-5):783-9.

PMID:
15714571
27.

Ultrastructural and functional investigations of adult hepatocyte spheroids during in vitro cultivation.

Dvir-Ginzberg M, Elkayam T, Aflalo ED, Agbaria R, Cohen S.

Tissue Eng. 2004 Nov-Dec;10(11-12):1806-17.

PMID:
15684689
30.

Herpes simplex virus thymidine kinase gene transduction enhances tumor growth rate and cyclooxygenase-2 expression in murine colon cancer cells.

Konson A, Ben-Kasus T, Mahajna JA, Danon A, Rimon G, Agbaria R.

Cancer Gene Ther. 2004 Dec;11(12):830-40.

PMID:
15359292
31.

Influence of the polydispersity of polymeric surfactants on the enantioselectivity of chiral compounds in micellar electrokinetic chromatography.

Tarus J, Agbaria RA, Morris K, Mwongela S, Numan A, Simuli L, Fletcher KA, Warner IM.

Langmuir. 2004 Aug 3;20(16):6887-95.

PMID:
15274600
32.
33.

Experimental and structural evidence that herpes 1 kinase and cellular DNA polymerase(s) discriminate on the basis of sugar pucker.

Marquez VE, Ben-Kasus T, Barchi JJ Jr, Green KM, Nicklaus MC, Agbaria R.

J Am Chem Soc. 2004 Jan 21;126(2):543-9.

PMID:
14719951
34.

Visual detection of cysteine and homocysteine.

Rusin O, St Luce NN, Agbaria RA, Escobedo JO, Jiang S, Warner IM, Dawan FB, Lian K, Strongin RM.

J Am Chem Soc. 2004 Jan 21;126(2):438-9.

35.

Copolymerized polymeric surfactants: characterization and application in micellar electrokinetic chromatography.

Akbay C, Gill NL, Agbaria RA, Warner IM.

Electrophoresis. 2003 Dec;24(24):4209-20.

PMID:
14679568
36.

Separation of achiral and chiral analytes using polymeric surfactants with ionic liquids as modifiers in micellar electrokinetic chromatography.

Mwongela SM, Numan A, Gill NL, Agbaria RA, Warner IM.

Anal Chem. 2003 Nov 15;75(22):6089-96.

PMID:
14615986
37.

Modulation of transcriptional activity by antioxidant carotenoids.

Sharoni Y, Agbaria R, Amir H, Ben-Dor A, Bobilev I, Doubi N, Giat Y, Hirsh K, Izumchenko G, Khanin M, Kirilov E, Krimer R, Nahum A, Steiner M, Walfisch Y, Walfisch S, Zango G, Danilenko M, Levy J.

Mol Aspects Med. 2003 Dec;24(6):371-84. Review.

PMID:
14585308
38.

Liver tissue engineering within alginate scaffolds: effects of cell-seeding density on hepatocyte viability, morphology, and function.

Dvir-Ginzberg M, Gamlieli-Bonshtein I, Agbaria R, Cohen S.

Tissue Eng. 2003 Aug;9(4):757-66.

PMID:
13678452
39.
40.

Enantioselectivity of alcohol-modified polymeric surfactants in micellar electrokinetic chromatography.

Tarus J, Agbaria RA, Morris K, Billiot FH, Williams AA, Chatman T, Warner IM.

Electrophoresis. 2003 Aug;24(15):2499-507.

PMID:
12900861
41.

Phosphorylation of 3'-azidothymidine in maternal and fetal peripheral blood mononuclear cells during gestation and at term.

Agbaria R, Manor E, Barak J, Balzarini J.

J Acquir Immune Defic Syndr. 2003 Apr 15;32(5):477-81.

PMID:
12679697
42.

High resolution three-dimensional visualization and characterization of coronary atherosclerosis in vitro by synchrotron radiation x-ray microtomography and highly localized x-ray diffraction.

Jin H, Ham K, Chan JY, Butler LG, Kurtz RL, Thiam S, Robinson JW, Agbaria RA, Warner IM, Tracy RE.

Phys Med Biol. 2002 Dec 21;47(24):4345-56.

PMID:
12539976
44.

Pharmacokinetics and organ distribution of N-methanocarbathymidine, a novel thymidine analog, in mice bearing tumors transduced with the herpes simplex thymidine kinase gene.

Noy R, Ben-Zvi Z, Elezra M, Candotti F, Ford H Jr, Morris JC, Marquez VE, Johns DG, Agbaria R.

Cancer Chemother Pharmacol. 2002 Nov;50(5):360-6. Epub 2002 Sep 20.

PMID:
12439593
45.

Molecular fluorescence, phosphorescence, and chemiluminescence spectrometry.

Agbaria RA, Oldham PB, McCarroll M, McGown LB, Warner IM.

Anal Chem. 2002 Aug 15;74(16):3952-62. Review. No abstract available.

PMID:
12199560
46.

Metabolic pathways of N-methanocarbathymidine, a novel antiviral agent, in native and herpes simplex virus type 1 infected Vero cells.

Zalah L, Huleihel M, Manor E, Konson A, Ford H Jr, Marquez VE, Johns DG, Agbaria R.

Antiviral Res. 2002 Jul;55(1):63-75.

PMID:
12076752
47.

Biosynthetic ganciclovir triphosphate: its isolation and characterization from ganciclovir-treated herpes simplex thymidine kinase-transduced murine cells.

Agbaria R, Candotti F, Kelley JA, Hao Z, Johns DG, Cooney DA, Blaese RM, Ford H Jr.

Biochem Biophys Res Commun. 2001 Nov 30;289(2):525-30.

PMID:
11716505
48.

Use of a herpes thymidine kinase/neomycin phosphotransferase chimeric gene for metabolic suicide gene transfer.

Candotti F, Agbaria R, Mullen CA, Touraine R, Balzarini J, Johns DG, Blaese RM.

Cancer Gene Ther. 2000 Apr;7(4):574-80.

49.

Hepatocyte behavior within three-dimensional porous alginate scaffolds.

Glicklis R, Shapiro L, Agbaria R, Merchuk JC, Cohen S.

Biotechnol Bioeng. 2000 Feb 5;67(3):344-53.

PMID:
10620265
50.

Amino acid order in polymeric dipeptide surfactants: effect on physical properties and enantioselectivity.

Billiot E, Agbaria RA, Thibodeaux S, Shamsi S, Warner IM.

Anal Chem. 1999 Apr 1;71(7):1252-6.

PMID:
10204030

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