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Items: 1 to 50 of 191

1.

An Ancient Lineage of Highly Divergent Parvoviruses Infects both Vertebrate and Invertebrate Hosts.

Pénzes JJ, de Souza WM, Agbandje-McKenna M, Gifford RJ.

Viruses. 2019 Jun 6;11(6). pii: E525. doi: 10.3390/v11060525.

2.

Adeno-Associated Virus VP1u Exhibits Protease Activity.

Kurian JJ, Lakshmanan R, Chmely WM, Hull JA, Yu JC, Bennett A, McKenna R, Agbandje-McKenna M.

Viruses. 2019 Apr 29;11(5). pii: E399. doi: 10.3390/v11050399.

3.

Twenty-Five Years of Structural Parvovirology.

Mietzsch M, Pénzes JJ, Agbandje-McKenna M.

Viruses. 2019 Apr 20;11(4). pii: E362. doi: 10.3390/v11040362. Review.

4.

XVIIth International Parvovirus Workshop.

Agbandje-McKenna M, Srivastava A.

Hum Gene Ther. 2019 Mar;30(3):252-256. doi: 10.1089/hum.2019.29084.mam. Epub 2019 Feb 26. No abstract available.

PMID:
30807259
5.

Protease-Activatable Adeno-Associated Virus Vector for Gene Delivery to Damaged Heart Tissue.

Guenther CM, Brun MJ, Bennett AD, Ho ML, Chen W, Zhu B, Lam M, Yamagami M, Kwon S, Bhattacharya N, Sousa D, Evans AC, Voss J, Sevick-Muraca EM, Agbandje-McKenna M, Suh J.

Mol Ther. 2019 Mar 6;27(3):611-622. doi: 10.1016/j.ymthe.2019.01.015. Epub 2019 Jan 29.

PMID:
30772143
6.

ICTV Virus Taxonomy Profile: Parvoviridae.

Cotmore SF, Agbandje-McKenna M, Canuti M, Chiorini JA, Eis-Hubinger AM, Hughes J, Mietzsch M, Modha S, Ogliastro M, Pénzes JJ, Pintel DJ, Qiu J, Soderlund-Venermo M, Tattersall P, Tijssen P, Ictv Report Consortium.

J Gen Virol. 2019 Mar;100(3):367-368. doi: 10.1099/jgv.0.001212. Epub 2019 Jan 23.

7.

Endogenous amdoparvovirus-related elements reveal insights into the biology and evolution of vertebrate parvoviruses.

Pénzes JJ, Marsile-Medun S, Agbandje-McKenna M, Gifford RJ.

Virus Evol. 2018 Nov 12;4(2):vey026. doi: 10.1093/ve/vey026. eCollection 2018 Jul.

8.

High-Resolution Structural Characterization of a New Adeno-associated Virus Serotype 5 Antibody Epitope toward Engineering Antibody-Resistant Recombinant Gene Delivery Vectors.

Jose A, Mietzsch M, Smith JK, Kurian J, Chipman P, McKenna R, Chiorini J, Agbandje-McKenna M.

J Virol. 2018 Dec 10;93(1). pii: e01394-18. doi: 10.1128/JVI.01394-18. Print 2019 Jan 1.

9.

Assembly and disassembly intermediates of maize streak geminivirus.

Bennett A, Rodriguez D, Lister S, Boulton M, McKenna R, Agbandje-McKenna M.

Virology. 2018 Dec;525:224-236. doi: 10.1016/j.virol.2018.09.011. Epub 2018 Oct 6.

PMID:
30300759
10.

Sub-2 Å Ewald curvature corrected structure of an AAV2 capsid variant.

Tan YZ, Aiyer S, Mietzsch M, Hull JA, McKenna R, Grieger J, Samulski RJ, Baker TS, Agbandje-McKenna M, Lyumkis D.

Nat Commun. 2018 Sep 7;9(1):3628. doi: 10.1038/s41467-018-06076-6.

11.

A novel adeno-associated virus capsid with enhanced neurotropism corrects a lysosomal transmembrane enzyme deficiency.

Tordo J, O'Leary C, Antunes ASLM, Palomar N, Aldrin-Kirk P, Basche M, Bennett A, D'Souza Z, Gleitz H, Godwin A, Holley RJ, Parker H, Liao AY, Rouse P, Youshani AS, Dridi L, Martins C, Levade T, Stacey KB, Davis DM, Dyer A, Clément N, Björklund T, Ali RR, Agbandje-McKenna M, Rahim AA, Pshezhetsky A, Waddington SN, Linden RM, Bigger BW, Henckaerts E.

Brain. 2018 Jul 1;141(7):2014-2031. doi: 10.1093/brain/awy126.

12.

Atomic structure of a rationally engineered gene delivery vector, AAV2.5.

Burg M, Rosebrough C, Drouin LM, Bennett A, Mietzsch M, Chipman P, McKenna R, Sousa D, Potter M, Byrne B, Jude Samulski R, Agbandje-McKenna M.

J Struct Biol. 2018 Sep;203(3):236-241. doi: 10.1016/j.jsb.2018.05.004. Epub 2018 May 18.

PMID:
29775653
13.

A Rationally Engineered Capsid Variant of AAV9 for Systemic CNS-Directed and Peripheral Tissue-Detargeted Gene Delivery in Neonates.

Wang D, Li S, Gessler DJ, Xie J, Zhong L, Li J, Tran K, Van Vliet K, Ren L, Su Q, He R, Goetzmann JE, Flotte TR, Agbandje-McKenna M, Gao G.

Mol Ther Methods Clin Dev. 2018 Mar 16;9:234-246. doi: 10.1016/j.omtm.2018.03.004. eCollection 2018 Jun 15.

14.

Creating an arsenal of Adeno-associated virus (AAV) gene delivery stealth vehicles.

Smith JK, Agbandje-McKenna M.

PLoS Pathog. 2018 May 3;14(5):e1006929. doi: 10.1371/journal.ppat.1006929. eCollection 2018 May.

15.

AAV6 K531 serves a dual function in selective receptor and antibody ADK6 recognition.

Bennett AD, Wong K, Lewis J, Tseng YS, Smith JK, Chipman P, McKenna R, Samulski RJ, Kleinschmidt J, Agbandje-McKenna M.

Virology. 2018 May;518:369-376. doi: 10.1016/j.virol.2018.03.007. Epub 2018 Mar 30.

16.

Optimizing the Targeting of Mouse Parvovirus 1 to Murine Melanoma Selects for Recombinant Genomes and Novel Mutations in the Viral Capsid Gene.

Marr M, D'Abramo A, Pittman N, Agbandje-McKenna M, Cotmore SF, Tattersall P.

Viruses. 2018 Jan 30;10(2). pii: E54. doi: 10.3390/v10020054.

17.

Atomic Resolution Structures of Human Bufaviruses Determined by Cryo-Electron Microscopy.

Ilyas M, Mietzsch M, Kailasan S, Väisänen E, Luo M, Chipman P, Smith JK, Kurian J, Sousa D, McKenna R, Söderlund-Venermo M, Agbandje-McKenna M.

Viruses. 2018 Jan 4;10(1). pii: E22. doi: 10.3390/v10010022.

18.

Atomic Resolution Structure of the Oncolytic Parvovirus LuIII by Electron Microscopy and 3D Image Reconstruction.

Pittman N, Misseldine A, Geilen L, Halder S, Smith JK, Kurian J, Chipman P, Janssen M, Mckenna R, Baker TS, D'Abramo A Jr, Cotmore S, Tattersall P, Agbandje-McKenna M.

Viruses. 2017 Oct 30;9(11). pii: E321. doi: 10.3390/v9110321.

19.

The Good That Viruses Do.

Mietzsch M, Agbandje-McKenna M.

Annu Rev Virol. 2017 Sep 29;4(1):iii-v. doi: 10.1146/annurev-vi-04-071217-100011. Review. No abstract available.

PMID:
28961414
20.

Rationally Engineered AAV Capsids Improve Transduction and Volumetric Spread in the CNS.

Kanaan NM, Sellnow RC, Boye SL, Coberly B, Bennett A, Agbandje-McKenna M, Sortwell CE, Hauswirth WW, Boye SE, Manfredsson FP.

Mol Ther Nucleic Acids. 2017 Sep 15;8:184-197. doi: 10.1016/j.omtn.2017.06.011. Epub 2017 Jun 21.

21.

Direct Head-to-Head Evaluation of Recombinant Adeno-associated Viral Vectors Manufactured in Human versus Insect Cells.

Kondratov O, Marsic D, Crosson SM, Mendez-Gomez HR, Moskalenko O, Mietzsch M, Heilbronn R, Allison JR, Green KB, Agbandje-McKenna M, Zolotukhin S.

Mol Ther. 2017 Dec 6;25(12):2661-2675. doi: 10.1016/j.ymthe.2017.08.003. Epub 2017 Aug 10.

22.

Thermal Stability as a Determinant of AAV Serotype Identity.

Bennett A, Patel S, Mietzsch M, Jose A, Lins-Austin B, Yu JC, Bothner B, McKenna R, Agbandje-McKenna M.

Mol Ther Methods Clin Dev. 2017 Jul 24;6:171-182. doi: 10.1016/j.omtm.2017.07.003. eCollection 2017 Sep 15.

23.

Structure-guided evolution of antigenically distinct adeno-associated virus variants for immune evasion.

Tse LV, Klinc KA, Madigan VJ, Castellanos Rivera RM, Wells LF, Havlik LP, Smith JK, Agbandje-McKenna M, Asokan A.

Proc Natl Acad Sci U S A. 2017 Jun 13;114(24):E4812-E4821. doi: 10.1073/pnas.1704766114. Epub 2017 May 30.

24.

Structural Insights into Human Bocaparvoviruses.

Mietzsch M, Kailasan S, Garrison J, Ilyas M, Chipman P, Kantola K, Janssen ME, Spear J, Sousa D, McKenna R, Brown K, Söderlund-Venermo M, Baker T, Agbandje-McKenna M.

J Virol. 2017 May 12;91(11). pii: e00261-17. doi: 10.1128/JVI.00261-17. Print 2017 Jun 1.

25.

OneBac 2.0: Sf9 Cell Lines for Production of AAV1, AAV2, and AAV8 Vectors with Minimal Encapsidation of Foreign DNA.

Mietzsch M, Hering H, Hammer EM, Agbandje-McKenna M, Zolotukhin S, Heilbronn R.

Hum Gene Ther Methods. 2017 Feb;28(1):15-22. doi: 10.1089/hgtb.2016.164.

26.

Parvovirus Capsid Structures Required for Infection: Mutations Controlling Receptor Recognition and Protease Cleavages.

Callaway HM, Feng KH, Lee DW, Allison AB, Pinard M, McKenna R, Agbandje-McKenna M, Hafenstein S, Parrish CR.

J Virol. 2017 Jan 3;91(2). pii: e01871-16. doi: 10.1128/JVI.01871-16. Print 2017 Jan 15.

27.

Cryo-electron Microscopy Reconstruction and Stability Studies of the Wild Type and the R432A Variant of Adeno-associated Virus Type 2 Reveal that Capsid Structural Stability Is a Major Factor in Genome Packaging.

Drouin LM, Lins B, Janssen M, Bennett A, Chipman P, McKenna R, Chen W, Muzyczka N, Cardone G, Baker TS, Agbandje-McKenna M.

J Virol. 2016 Sep 12;90(19):8542-51. doi: 10.1128/JVI.00575-16. Print 2016 Oct 1.

28.

The Structure of Carbonic Anhydrase IX Is Adapted for Low-pH Catalysis.

Mahon BP, Bhatt A, Socorro L, Driscoll JM, Okoh C, Lomelino CL, Mboge MY, Kurian JJ, Tu C, Agbandje-McKenna M, Frost SC, McKenna R.

Biochemistry. 2016 Aug 23;55(33):4642-53. doi: 10.1021/acs.biochem.6b00243. Epub 2016 Aug 5.

29.

Generation and characterization of anti-Adeno-associated virus serotype 8 (AAV8) and anti-AAV9 monoclonal antibodies.

Tseng YS, Vliet KV, Rao L, McKenna R, Byrne BJ, Asokan A, Agbandje-McKenna M.

J Virol Methods. 2016 Oct;236:105-110. doi: 10.1016/j.jviromet.2016.07.009. Epub 2016 Jul 14.

30.

Cryoannealing-induced space-group transition of crystals of the carbonic anhydrase psCA3.

Pinard MA, Kurian JJ, Aggarwal M, Agbandje-McKenna M, McKenna R.

Acta Crystallogr F Struct Biol Commun. 2016 Jul;72(Pt 7):573-7. doi: 10.1107/S2053230X16009286. Epub 2016 Jun 28.

31.

Germline viral "fossils" guide in silico reconstruction of a mid-Cenozoic era marsupial adeno-associated virus.

Smith RH, Hallwirth CV, Westerman M, Hetherington NA, Tseng YS, Cecchini S, Virag T, Ziegler ML, Rogozin IB, Koonin EV, Agbandje-McKenna M, Kotin RM, Alexander IE.

Sci Rep. 2016 Jul 5;6:28965. doi: 10.1038/srep28965.

32.

Mutants at the 2-Fold Interface of Adeno-associated Virus Type 2 (AAV2) Structural Proteins Suggest a Role in Viral Transcription for AAV Capsids.

Aydemir F, Salganik M, Resztak J, Singh J, Bennett A, Agbandje-McKenna M, Muzyczka N.

J Virol. 2016 Jul 27;90(16):7196-7204. doi: 10.1128/JVI.00493-16. Print 2016 Aug 15.

33.

Characterization of the Adeno-Associated Virus 1 and 6 Sialic Acid Binding Site.

Huang LY, Patel A, Ng R, Miller EB, Halder S, McKenna R, Asokan A, Agbandje-McKenna M.

J Virol. 2016 May 12;90(11):5219-5230. doi: 10.1128/JVI.00161-16. Print 2016 Jun 1.

34.

Parvovirus Family Conundrum: What Makes a Killer?

Kailasan S, Agbandje-McKenna M, Parrish CR.

Annu Rev Virol. 2015 Nov;2(1):425-50. doi: 10.1146/annurev-virology-100114-055150. Epub 2015 Aug 26. Review.

PMID:
26958923
35.

Mapping Antigenic Epitopes on the Human Bocavirus Capsid.

Kailasan S, Garrison J, Ilyas M, Chipman P, McKenna R, Kantola K, Söderlund-Venermo M, Kučinskaitė-Kodzė I, Žvirblienė A, Agbandje-McKenna M.

J Virol. 2016 Apr 14;90(9):4670-4680. doi: 10.1128/JVI.02998-15. Print 2016 May.

36.

Impact of Heparan Sulfate Binding on Transduction of Retina by Recombinant Adeno-Associated Virus Vectors.

Boye SL, Bennett A, Scalabrino ML, McCullough KT, Van Vliet K, Choudhury S, Ruan Q, Peterson J, Agbandje-McKenna M, Boye SE.

J Virol. 2016 Mar 28;90(8):4215-4231. doi: 10.1128/JVI.00200-16. Print 2016 Apr.

37.

Site-Directed Mutagenesis of Surface-Exposed Lysine Residues Leads to Improved Transduction by AAV2, But Not AAV8, Vectors in Murine Hepatocytes In Vivo.

Li B, Ma W, Ling C, Van Vliet K, Huang LY, Agbandje-McKenna M, Srivastava A, Aslanidi GV.

Hum Gene Ther Methods. 2015 Dec;26(6):211-20. doi: 10.1089/hgtb.2015.115. Epub 2015 Oct 27.

38.

Structure of neurotropic adeno-associated virus AAVrh.8.

Halder S, Van Vliet K, Smith JK, Duong TT, McKenna R, Wilson JM, Agbandje-McKenna M.

J Struct Biol. 2015 Oct;192(1):21-36. doi: 10.1016/j.jsb.2015.08.017. Epub 2015 Aug 31.

39.

Structural and biophysical characterization of the α-carbonic anhydrase from the gammaproteobacterium Thiomicrospira crunogena XCL-2: insights into engineering thermostable enzymes for CO2 sequestration.

Díaz-Torres NA, Mahon BP, Boone CD, Pinard MA, Tu C, Ng R, Agbandje-McKenna M, Silverman D, Scott K, McKenna R.

Acta Crystallogr D Biol Crystallogr. 2015 Aug;71(Pt 8):1745-56. doi: 10.1107/S1399004715012183. Epub 2015 Jul 31.

40.

Development of Patient-specific AAV Vectors After Neutralizing Antibody Selection for Enhanced Muscle Gene Transfer.

Li C, Wu S, Albright B, Hirsch M, Li W, Tseng YS, Agbandje-McKenna M, McPhee S, Asokan A, Samulski RJ.

Mol Ther. 2016 Feb;24(1):53-65. doi: 10.1038/mt.2015.134. Epub 2015 Jul 29.

41.

Structure of an enteric pathogen, bovine parvovirus.

Kailasan S, Halder S, Gurda B, Bladek H, Chipman PR, McKenna R, Brown K, Agbandje-McKenna M.

J Virol. 2015 Mar;89(5):2603-14. doi: 10.1128/JVI.03157-14. Epub 2014 Dec 17.

42.

Adeno-associated virus serotype 1 (AAV1)- and AAV5-antibody complex structures reveal evolutionary commonalities in parvovirus antigenic reactivity.

Tseng YS, Gurda BL, Chipman P, McKenna R, Afione S, Chiorini JA, Muzyczka N, Olson NH, Baker TS, Kleinschmidt J, Agbandje-McKenna M.

J Virol. 2015 Feb;89(3):1794-808. doi: 10.1128/JVI.02710-14. Epub 2014 Nov 19.

43.

Identification and mutagenesis of the adeno-associated virus 5 sialic acid binding region.

Afione S, DiMattia MA, Halder S, Di Pasquale G, Agbandje-McKenna M, Chiorini JA.

J Virol. 2015 Feb;89(3):1660-72. doi: 10.1128/JVI.02503-14. Epub 2014 Nov 19.

44.

The ins and outs of viral infection: keystone meeting review.

Bird SW, Kirkegaard K, Agbandje-McKenna M, Freed EO.

Viruses. 2014 Sep 25;6(9):3652-62. doi: 10.3390/v6093652.

45.

Vector design Tour de Force: integrating combinatorial and rational approaches to derive novel adeno-associated virus variants.

Marsic D, Govindasamy L, Currlin S, Markusic DM, Tseng YS, Herzog RW, Agbandje-McKenna M, Zolotukhin S.

Mol Ther. 2014 Nov;22(11):1900-9. doi: 10.1038/mt.2014.139. Epub 2014 Jul 22.

46.

Parvovirus glycan interactions.

Huang LY, Halder S, Agbandje-McKenna M.

Curr Opin Virol. 2014 Aug;7:108-18. doi: 10.1016/j.coviro.2014.05.007. Epub 2014 Jul 19. Review.

47.

Gene transfer properties and structural modeling of human stem cell-derived AAV.

Smith LJ, Ul-Hasan T, Carvaines SK, Van Vliet K, Yang E, Wong KK Jr, Agbandje-McKenna M, Chatterjee S.

Mol Ther. 2014 Sep;22(9):1625-34. doi: 10.1038/mt.2014.107. Epub 2014 Jun 13.

48.

Tunable protease-activatable virus nanonodes.

Judd J, Ho ML, Tiwari A, Gomez EJ, Dempsey C, Van Vliet K, Igoshin OA, Silberg JJ, Agbandje-McKenna M, Suh J.

ACS Nano. 2014 May 27;8(5):4740-6. doi: 10.1021/nn500550q. Epub 2014 May 5.

49.

Defining the stoichiometry and cargo load of viral and bacterial nanoparticles by Orbitrap mass spectrometry.

Snijder J, van de Waterbeemd M, Damoc E, Denisov E, Grinfeld D, Bennett A, Agbandje-McKenna M, Makarov A, Heck AJ.

J Am Chem Soc. 2014 May 21;136(20):7295-9. doi: 10.1021/ja502616y. Epub 2014 May 7.

50.

The structure of AAVrh32.33, a novel gene delivery vector.

Mikals K, Nam HJ, Van Vliet K, Vandenberghe LH, Mays LE, McKenna R, Wilson JM, Agbandje-McKenna M.

J Struct Biol. 2014 May;186(2):308-17. doi: 10.1016/j.jsb.2014.03.020. Epub 2014 Apr 2.

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