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Items: 1 to 50 of 54

1.

N-(phosphonacetyl)-L-aspartate induces TAp73-dependent apoptosis by modulating multiple Bcl-2 proteins: potential for cancer therapy.

Ruhul Amin AR, Thakur VS, Gupta K, Agarwal MK, Wald DN, Shin DM, Agarwal ML.

Oncogene. 2013 Feb 14;32(7):920-9. doi: 10.1038/onc.2012.96. Epub 2012 Mar 19.

2.

Securinine, a myeloid differentiation agent with therapeutic potential for AML.

Gupta K, Chakrabarti A, Rana S, Ramdeo R, Roth BL, Agarwal ML, Tse W, Agarwal MK, Wald DN.

PLoS One. 2011;6(6):e21203. doi: 10.1371/journal.pone.0021203. Epub 2011 Jun 24.

3.

p53-Dependent p21-mediated growth arrest pre-empts and protects HCT116 cells from PUMA-mediated apoptosis induced by EGCG.

Thakur VS, Ruhul Amin AR, Paul RK, Gupta K, Hastak K, Agarwal MK, Jackson MW, Wald DN, Mukhtar H, Agarwal ML.

Cancer Lett. 2010 Oct 28;296(2):225-32. doi: 10.1016/j.canlet.2010.04.012. Epub 2010 May 4.

4.

Securinine induces p73-dependent apoptosis preferentially in p53-deficient colon cancer cells.

Rana S, Gupta K, Gomez J, Matsuyama S, Chakrabarti A, Agarwal ML, Agarwal A, Agarwal MK, Wald DN.

FASEB J. 2010 Jun;24(6):2126-34. doi: 10.1096/fj.09-148999. Epub 2010 Feb 4.

PMID:
20133503
5.

Restoration of p53 functions protects cells from concanavalin A-induced apoptosis.

Amin AR, Thakur VS, Gupta K, Jackson MW, Harada H, Agarwal MK, Shin DM, Wald DN, Agarwal ML.

Mol Cancer Ther. 2010 Feb;9(2):471-9. doi: 10.1158/1535-7163.MCT-09-0732. Epub 2010 Feb 2.

6.

Identification of 6-benzylthioinosine as a myeloid leukemia differentiation-inducing compound.

Wald DN, Vermaat HM, Zang S, Lavik A, Kang Z, Peleg G, Gerson SL, Bunting KD, Agarwal ML, Roth BL, Tse W.

Cancer Res. 2008 Jun 1;68(11):4369-76. doi: 10.1158/0008-5472.CAN-07-6559.

7.

DNA synthesis from unbalanced nucleotide pools causes limited DNA damage that triggers ATR-CHK1-dependent p53 activation.

Hastak K, Paul RK, Agarwal MK, Thakur VS, Amin AR, Agrawal S, Sramkoski RM, Jacobberger JW, Jackson MW, Stark GR, Agarwal ML.

Proc Natl Acad Sci U S A. 2008 Apr 29;105(17):6314-9. doi: 10.1073/pnas.0802080105. Epub 2008 Apr 23.

8.

A role for SHPS-1/SIRPalpha in Concanavalin A-dependent production of MMP-9.

Ruhul Amin AR, Uddin Biswas MH, Senga T, Feng GS, Kannagi R, Agarwal ML, Hamaguchi M.

Genes Cells. 2007 Sep;12(9):1023-33.

9.
10.

SHP-2 tyrosine phosphatase inhibits p73-dependent apoptosis and expression of a subset of p53 target genes induced by EGCG.

Amin AR, Thakur VS, Paul RK, Feng GS, Qu CK, Mukhtar H, Agarwal ML.

Proc Natl Acad Sci U S A. 2007 Mar 27;104(13):5419-24. Epub 2007 Mar 16.

11.

DNA replication licensing factor minichromosome maintenance deficient 5 rescues p53-mediated growth arrest.

Agarwal MK, Ruhul Amin AR, Agarwal ML.

Cancer Res. 2007 Jan 1;67(1):116-21.

12.

Macrophage inhibitory cytokine 1 mediates a p53-dependent protective arrest in S phase in response to starvation for DNA precursors.

Agarwal MK, Hastak K, Jackson MW, Breit SN, Stark GR, Agarwal ML.

Proc Natl Acad Sci U S A. 2006 Oct 31;103(44):16278-83. Epub 2006 Oct 18.

13.

p130/p107/p105Rb-dependent transcriptional repression during DNA-damage-induced cell-cycle exit at G2.

Jackson MW, Agarwal MK, Yang J, Bruss P, Uchiumi T, Agarwal ML, Stark GR, Taylor WR.

J Cell Sci. 2005 May 1;118(Pt 9):1821-32. Epub 2005 Apr 12.

14.

Ablation of either p21 or Bax prevents p53-dependent apoptosis induced by green tea polyphenol epigallocatechin-3-gallate.

Hastak K, Agarwal MK, Mukhtar H, Agarwal ML.

FASEB J. 2005 May;19(7):789-91. Epub 2005 Mar 11.

PMID:
15764647
15.

In vivo recombinant adenovirus-mediated p53 gene therapy in a syngeneic rat model for colorectal cancer.

Baek JH, Agarwal ML, Tubbs RR, Vladisavljevic A, Tomita H, Bukowski RM, Milsom JW, Kim JM, Kwak JY.

J Korean Med Sci. 2004 Dec;19(6):834-41.

16.

The Wilms tumor suppressor-1 target gene podocalyxin is transcriptionally repressed by p53.

Stanhope-Baker P, Kessler PM, Li W, Agarwal ML, Williams BR.

J Biol Chem. 2004 Aug 6;279(32):33575-85. Epub 2004 May 21.

17.

Limited role of N-terminal phosphoserine residues in the activation of transcription by p53.

Jackson MW, Agarwal MK, Agarwal ML, Agarwal A, Stanhope-Baker P, Williams BR, Stark GR.

Oncogene. 2004 May 27;23(25):4477-87.

PMID:
15064747
18.
19.

Role of p53 and NF-kappaB in epigallocatechin-3-gallate-induced apoptosis of LNCaP cells.

Hastak K, Gupta S, Ahmad N, Agarwal MK, Agarwal ML, Mukhtar H.

Oncogene. 2003 Jul 31;22(31):4851-9.

PMID:
12894226
20.

Stat1-dependent, p53-independent expression of p21(waf1) modulates oxysterol-induced apoptosis.

Agrawal S, Agarwal ML, Chatterjee-Kishore M, Stark GR, Chisolm GM.

Mol Cell Biol. 2002 Apr;22(7):1981-92.

21.

Regulation of p53 expression by the RAS-MAP kinase pathway.

Agarwal ML, Ramana CV, Hamilton M, Taylor WR, DePrimo SE, Bean LJ, Agarwal A, Agarwal MK, Wolfman A, Stark GR.

Oncogene. 2001 May 3;20(20):2527-36.

22.

Mechanisms of G2 arrest in response to overexpression of p53.

Taylor WR, DePrimo SE, Agarwal A, Agarwal ML, Schönthal AH, Katula KS, Stark GR.

Mol Biol Cell. 1999 Nov;10(11):3607-22.

23.

p53 inhibits entry into mitosis when DNA synthesis is blocked.

Taylor WR, Agarwal ML, Agarwal A, Stacey DW, Stark GR.

Oncogene. 1999 Jan 14;18(2):283-95.

24.

A p53-dependent S-phase checkpoint helps to protect cells from DNA damage in response to starvation for pyrimidine nucleotides.

Agarwal ML, Agarwal A, Taylor WR, Chernova O, Sharma Y, Stark GR.

Proc Natl Acad Sci U S A. 1998 Dec 8;95(25):14775-80.

26.

The p53 network.

Agarwal ML, Taylor WR, Chernov MV, Chernova OB, Stark GR.

J Biol Chem. 1998 Jan 2;273(1):1-4. Review. No abstract available.

27.

MYC abrogates p53-mediated cell cycle arrest in N-(phosphonacetyl)-L-aspartate-treated cells, permitting CAD gene amplification.

Chernova OB, Chernov MV, Ishizaka Y, Agarwal ML, Stark GR.

Mol Cell Biol. 1998 Jan;18(1):536-45.

28.

Defective induction but normal activation and function of p53 in mouse cells lacking poly-ADP-ribose polymerase.

Agarwal ML, Agarwal A, Taylor WR, Wang ZQ, Wagner EF, Stark GR.

Oncogene. 1997 Aug 28;15(9):1035-41.

29.

Multiple mechanisms of N-phosphonacetyl-L-aspartate resistance in human cell lines: carbamyl-P synthetase/aspartate transcarbamylase/dihydro-orotase gene amplification is frequent only when chromosome 2 is rearranged.

Smith KA, Chernova OB, Groves RP, Stark MB, Martínez JL, Davidson JN, Trent JM, Patterson TE, Agarwal A, Duncan P, Agarwal ML, Stark GR.

Proc Natl Acad Sci U S A. 1997 Mar 4;94(5):1816-21.

30.

The induction of partial resistance to photodynamic therapy by the protooncogene BCL-2.

He J, Agarwal ML, Larkin HE, Friedman LR, Xue LY, Oleinick NL.

Photochem Photobiol. 1996 Nov;64(5):845-52.

PMID:
8931384
31.

The role of p53 in regulating genomic stability when DNA and RNA synthesis are inhibited.

Chernova OB, Chernov MV, Agarwal ML, Taylor WR, Stark GR.

Trends Biochem Sci. 1995 Oct;20(10):431-4. Review.

PMID:
8533158
32.

p53 controls both the G2/M and the G1 cell cycle checkpoints and mediates reversible growth arrest in human fibroblasts.

Agarwal ML, Agarwal A, Taylor WR, Stark GR.

Proc Natl Acad Sci U S A. 1995 Aug 29;92(18):8493-7.

33.

Elevation of GRP-78 and loss of HSP-70 following photodynamic treatment of V79 cells: sensitization by nigericin.

Xue LY, Agarwal ML, Varnes ME.

Photochem Photobiol. 1995 Jul;62(1):135-43.

PMID:
7638257
34.

Regulation and mechanisms of gene amplification.

Smith KA, Agarwal ML, Chernov MV, Chernova OB, Deguchi Y, Ishizaka Y, Patterson TE, Poupon MF, Stark GR.

Philos Trans R Soc Lond B Biol Sci. 1995 Jan 30;347(1319):49-56. Review.

PMID:
7746853
35.

Phospholipase activation triggers apoptosis in photosensitized mouse lymphoma cells.

Agarwal ML, Larkin HE, Zaidi SI, Mukhtar H, Oleinick NL.

Cancer Res. 1993 Dec 15;53(24):5897-902.

PMID:
8261400
36.

The flax ribosomal RNA-encoding genes are arranged in tandem at a single locus interspersed by 'non-rDNA' sequences.

Agarwal ML, Aldrich J, Agarwal A, Cullis CA.

Gene. 1992 Oct 21;120(2):151-6.

PMID:
1398131
37.

Photodynamic therapy induces rapid cell death by apoptosis in L5178Y mouse lymphoma cells.

Agarwal ML, Clay ME, Harvey EJ, Evans HH, Antunez AR, Oleinick NL.

Cancer Res. 1991 Nov 1;51(21):5993-6.

38.

The ubiquitin-encoding multigene family of flax, Linum usitatissimum.

Agarwal ML, Cullis CA.

Gene. 1991 Mar 1;99(1):69-75.

PMID:
1850710
39.

Socio demographic variables in unipolar and bipolar illness.

Agarwal ML, Singh G.

Indian J Psychiatry. 1982 Apr;24(2):155-8. No abstract available.

40.

Unilateral cryptophthalmos.

Baijal GC, Agarwal ML, Chaurasia BD.

Indian J Ophthalmol. 1981 Apr;29(1):41-2. No abstract available.

41.

A family and genetic study of primary affective disorders.

Singh G, Agarwal ML.

Indian J Psychiatry. 1980 Jan;22(1):39-50. No abstract available.

42.

Leukaemic deposits in the orbit.

Baijal GC, Agarwal ML, Gawande C, Gupta DC.

Indian J Ophthalmol. 1979 Jan;26(4):53-5. No abstract available.

43.

Fibrinogen content and fibrinolytic activity of blood in diabetics, before and after antidiabetic drugs.

Bedi HK, Vyas BR, Bomb BS, Agarwal ML, Bedi T.

J Assoc Physicians India. 1977 Mar;25(3):181-5. No abstract available.

PMID:
914747
44.

Dacryocystography and lacrimal probing in cases of congenital obstruction of nasolacrimal duct.

Agarwal ML, Gupta BP.

Indian J Ophthalmol. 1976 Oct;24(3):30-2. No abstract available.

45.

Platelet adhesiveness in cases of diabetes mellitus before and after antidiabetic drugs.

Bedi HK, Vyas BR, Bomb BS, Agarwal ML, Bedi T.

J Assoc Physicians India. 1976 Oct;24(10):645-8. No abstract available.

PMID:
1025105
46.

Dacryocystography and surgery in pseudo sac.

Agarwal ML, Gupta VK, Gandotra VK, Baijal GC.

Indian J Ophthalmol. 1976 Jul;24(2):29-31. No abstract available.

47.

A comparative clinical study with ethacridine lactate and a combination of chloramphenicol-streptomycin in the treatment of diarrhoea.

Bhandari B, Agarwal ML, Punglia JL.

Indian Pediatr. 1973 Dec;10(12):725-7. No abstract available.

PMID:
4788853
48.

Postural hypotension: body fluid compartments and electrolytes.

Cox JR, Admani AK, Agarwal ML, Abel P.

Age Ageing. 1973 May;2(2):112-20. No abstract available.

PMID:
4778611
49.

Dacryocystorhinostomy with preparation of a horizontally oval bony ostium.

Agarwal ML.

J All India Ophthalmol Soc. 1970 Jun;18(2):69-74. No abstract available.

PMID:
5499248
50.

Cavernous sinus thrombophlebitis due to a boil on ala nasi.

Agarwal ML.

J All India Ophthalmol Soc. 1967 Oct;15(5):189-92. No abstract available.

PMID:
5601093

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