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Items: 1 to 50 of 71

1.

SMAC mimetics promote NIK-dependent inhibition of CD4+ TH17 cell differentiation.

Rizk J, Kaplinsky J, Agerholm R, Kadekar D, Ivars F, Agace WW, Wong WW, Szucs MJ, Myers SA, Carr SA, Waisman A, Bekiaris V.

Sci Signal. 2019 Aug 27;12(596). pii: eaaw3469. doi: 10.1126/scisignal.aaw3469.

PMID:
31455723
2.

Retinoic Acid Signaling in Thymic Epithelial Cells Regulates Thymopoiesis.

Wendland K, Niss K, Kotarsky K, Wu NYH, White AJ, Jendholm J, Rivollier A, Izarzugaza JMG, Brunak S, Holländer GA, Anderson G, Sitnik KM, Agace WW.

J Immunol. 2018 Jul 15;201(2):524-532. doi: 10.4049/jimmunol.1800418. Epub 2018 May 30.

3.

CD103+CD11b+ mucosal classical dendritic cells initiate long-term switched antibody responses to flagellin.

Flores-Langarica A, Müller Luda K, Persson EK, Cook CN, Bobat S, Marshall JL, Dahlgren MW, Hägerbrand K, Toellner KM, Goodall MD, Withers DR, Henderson IR, Johansson Lindbom B, Cunningham AF, Agace WW.

Mucosal Immunol. 2018 May;11(3):681-692. doi: 10.1038/mi.2017.105. Epub 2017 Dec 20.

4.

Distinct DC subsets regulate adaptive Th1 and 2 responses during Trichuris muris infection.

Demiri M, Müller-Luda K, Agace WW, Svensson-Frej M.

Parasite Immunol. 2017 Oct;39(10). doi: 10.1111/pim.12458. Epub 2017 Sep 5.

5.

Irf4-dependent CD103+CD11b+ dendritic cells and the intestinal microbiome regulate monocyte and macrophage activation and intestinal peristalsis in postoperative ileus.

Pohl JM, Gutweiler S, Thiebes S, Volke JK, Klein-Hitpass L, Zwanziger D, Gunzer M, Jung S, Agace WW, Kurts C, Engel DR.

Gut. 2017 Dec;66(12):2110-2120. doi: 10.1136/gutjnl-2017-313856. Epub 2017 Jun 14. Erratum in: Gut. 2018 Feb;67(2):379.

6.

Different populations of CD11b+ dendritic cells drive Th2 responses in the small intestine and colon.

Mayer JU, Demiri M, Agace WW, MacDonald AS, Svensson-Frej M, Milling SW.

Nat Commun. 2017 Jun 9;8:15820. doi: 10.1038/ncomms15820.

7.

Regionalized Development and Maintenance of the Intestinal Adaptive Immune Landscape.

Agace WW, McCoy KD.

Immunity. 2017 Apr 18;46(4):532-548. doi: 10.1016/j.immuni.2017.04.004. Review.

8.

Diversity and functions of intestinal mononuclear phagocytes.

Joeris T, Müller-Luda K, Agace WW, Mowat AM.

Mucosal Immunol. 2017 Jul;10(4):845-864. doi: 10.1038/mi.2017.22. Epub 2017 Apr 5. Review.

PMID:
28378807
9.

Eosinophils are key regulators of perivascular adipose tissue and vascular functionality.

Withers SB, Forman R, Meza-Perez S, Sorobetea D, Sitnik K, Hopwood T, Lawrence CB, Agace WW, Else KJ, Heagerty AM, Svensson-Frej M, Cruickshank SM.

Sci Rep. 2017 Mar 17;7:44571. doi: 10.1038/srep44571.

10.

IRF8 Transcription Factor Controls Survival and Function of Terminally Differentiated Conventional and Plasmacytoid Dendritic Cells, Respectively.

Sichien D, Scott CL, Martens L, Vanderkerken M, Van Gassen S, Plantinga M, Joeris T, De Prijck S, Vanhoutte L, Vanheerswynghels M, Van Isterdael G, Toussaint W, Madeira FB, Vergote K, Agace WW, Clausen BE, Hammad H, Dalod M, Saeys Y, Lambrecht BN, Guilliams M.

Immunity. 2016 Sep 20;45(3):626-640. doi: 10.1016/j.immuni.2016.08.013. Epub 2016 Sep 13.

11.

Long-term persistence of human donor alveolar macrophages in lung transplant recipients.

Eguíluz-Gracia I, Schultz HH, Sikkeland LI, Danilova E, Holm AM, Pronk CJ, Agace WW, Iversen M, Andersen C, Jahnsen FL, Baekkevold ES.

Thorax. 2016 Nov;71(11):1006-1011. doi: 10.1136/thoraxjnl-2016-208292. Epub 2016 Jun 21.

PMID:
27329043
12.

IRF8 Transcription-Factor-Dependent Classical Dendritic Cells Are Essential for Intestinal T Cell Homeostasis.

Luda KM, Joeris T, Persson EK, Rivollier A, Demiri M, Sitnik KM, Pool L, Holm JB, Melo-Gonzalez F, Richter L, Lambrecht BN, Kristiansen K, Travis MA, Svensson-Frej M, Kotarsky K, Agace WW.

Immunity. 2016 Apr 19;44(4):860-74. doi: 10.1016/j.immuni.2016.02.008. Epub 2016 Apr 5.

13.

IL-18Rα-deficient CD4(+) T cells induce intestinal inflammation in the CD45RB(hi) transfer model of colitis despite impaired innate responsiveness.

Holmkvist P, Pool L, Hägerbrand K, Agace WW, Rivollier A.

Eur J Immunol. 2016 Jun;46(6):1371-82. doi: 10.1002/eji.201545957. Epub 2016 May 6.

14.

Context-Dependent Development of Lymphoid Stroma from Adult CD34(+) Adventitial Progenitors.

Sitnik KM, Wendland K, Weishaupt H, Uronen-Hansson H, White AJ, Anderson G, Kotarsky K, Agace WW.

Cell Rep. 2016 Mar 15;14(10):2375-88. doi: 10.1016/j.celrep.2016.02.033. Epub 2016 Mar 3.

15.

Macrophage and dendritic cell subsets in IBD: ALDH+ cells are reduced in colon tissue of patients with ulcerative colitis regardless of inflammation.

Magnusson MK, Brynjólfsson SF, Dige A, Uronen-Hansson H, Börjesson LG, Bengtsson JL, Gudjonsson S, Öhman L, Agnholt J, Sjövall H, Agace WW, Wick MJ.

Mucosal Immunol. 2016 Jan;9(1):171-82. doi: 10.1038/mi.2015.48. Epub 2015 Jun 17.

16.

CCRL1/ACKR4 is expressed in key thymic microenvironments but is dispensable for T lymphopoiesis at steady state in adult mice.

Lucas B, White AJ, Ulvmar MH, Nibbs RJ, Sitnik KM, Agace WW, Jenkinson WE, Anderson G, Rot A.

Eur J Immunol. 2015 Feb;45(2):574-83. doi: 10.1002/eji.201445015. Epub 2015 Jan 16.

17.

A major population of mucosal memory CD4+ T cells, coexpressing IL-18Rα and DR3, display innate lymphocyte functionality.

Holmkvist P, Roepstorff K, Uronen-Hansson H, Sandén C, Gudjonsson S, Patschan O, Grip O, Marsal J, Schmidtchen A, Hornum L, Erjefält JS, Håkansson K, Agace WW.

Mucosal Immunol. 2015 May;8(3):545-58. doi: 10.1038/mi.2014.87. Epub 2014 Oct 1.

18.

Regional specialization within the intestinal immune system.

Mowat AM, Agace WW.

Nat Rev Immunol. 2014 Oct;14(10):667-85. doi: 10.1038/nri3738. Epub 2014 Sep 19. Review.

PMID:
25234148
19.

CCR2(+)CD103(-) intestinal dendritic cells develop from DC-committed precursors and induce interleukin-17 production by T cells.

Scott CL, Bain CC, Wright PB, Sichien D, Kotarsky K, Persson EK, Luda K, Guilliams M, Lambrecht BN, Agace WW, Milling SW, Mowat AM.

Mucosal Immunol. 2015 Mar;8(2):327-39. doi: 10.1038/mi.2014.70. Epub 2014 Aug 20.

20.

Involvement of neurons and retinoic acid in lymphatic development: new insights in increased nuchal translucency.

Burger NB, Stuurman KE, Kok E, Konijn T, Schooneman D, Niederreither K, Coles M, Agace WW, Christoffels VM, Mebius RE, van de Pavert SA, Bekker MN.

Prenat Diagn. 2014 Dec;34(13):1312-9. doi: 10.1002/pd.4473. Epub 2014 Aug 22.

PMID:
25088217
21.

Intestinal dendritic cells in the regulation of mucosal immunity.

Bekiaris V, Persson EK, Agace WW.

Immunol Rev. 2014 Jul;260(1):86-101. doi: 10.1111/imr.12194. Review.

PMID:
24942684
22.

Lymph-borne CD8α+ dendritic cells are uniquely able to cross-prime CD8+ T cells with antigen acquired from intestinal epithelial cells.

Cerovic V, Houston SA, Westlund J, Utriainen L, Davison ES, Scott CL, Bain CC, Joeris T, Agace WW, Kroczek RA, Mowat AM, Yrlid U, Milling SW.

Mucosal Immunol. 2015 Jan;8(1):38-48. doi: 10.1038/mi.2014.40. Epub 2014 May 21.

23.

Dendritic cell subsets in the intestinal lamina propria: ontogeny and function.

Persson EK, Scott CL, Mowat AM, Agace WW.

Eur J Immunol. 2013 Dec;43(12):3098-107. doi: 10.1002/eji.201343740. Epub 2013 Aug 21. Review.

24.

IRF4 transcription-factor-dependent CD103(+)CD11b(+) dendritic cells drive mucosal T helper 17 cell differentiation.

Persson EK, Uronen-Hansson H, Semmrich M, Rivollier A, Hägerbrand K, Marsal J, Gudjonsson S, Håkansson U, Reizis B, Kotarsky K, Agace WW.

Immunity. 2013 May 23;38(5):958-69. doi: 10.1016/j.immuni.2013.03.009. Epub 2013 May 9.

25.

Resident and pro-inflammatory macrophages in the colon represent alternative context-dependent fates of the same Ly6Chi monocyte precursors.

Bain CC, Scott CL, Uronen-Hansson H, Gudjonsson S, Jansson O, Grip O, Guilliams M, Malissen B, Agace WW, Mowat AM.

Mucosal Immunol. 2013 May;6(3):498-510. doi: 10.1038/mi.2012.89. Epub 2012 Sep 19.

26.

Targeting T-cell migration in inflammatory bowel disease.

Marsal J, Agace WW.

J Intern Med. 2012 Nov;272(5):411-29. doi: 10.1111/j.1365-2796.2012.02588.x. Epub 2012 Oct 15. Review.

27.

Mesenchymal cells regulate retinoic acid receptor-dependent cortical thymic epithelial cell homeostasis.

Sitnik KM, Kotarsky K, White AJ, Jenkinson WE, Anderson G, Agace WW.

J Immunol. 2012 May 15;188(10):4801-9. doi: 10.4049/jimmunol.1200358. Epub 2012 Apr 13.

28.

DNGR-1 is a specific and universal marker of mouse and human Batf3-dependent dendritic cells in lymphoid and nonlymphoid tissues.

Poulin LF, Reyal Y, Uronen-Hansson H, Schraml BU, Sancho D, Murphy KM, Håkansson UK, Moita LF, Agace WW, Bonnet D, Reis e Sousa C.

Blood. 2012 Jun 21;119(25):6052-62. doi: 10.1182/blood-2012-01-406967. Epub 2012 Mar 22.

PMID:
22442345
29.

Directed antigen targeting in vivo identifies a role for CD103+ dendritic cells in both tolerogenic and immunogenic T-cell responses.

Semmrich M, Plantinga M, Svensson-Frej M, Uronen-Hansson H, Gustafsson T, Mowat AM, Yrlid U, Lambrecht BN, Agace WW.

Mucosal Immunol. 2012 Mar;5(2):150-60. doi: 10.1038/mi.2011.61. Epub 2011 Dec 14.

30.

How vitamin A metabolizing dendritic cells are generated in the gut mucosa.

Agace WW, Persson EK.

Trends Immunol. 2012 Jan;33(1):42-8. doi: 10.1016/j.it.2011.10.001. Epub 2011 Nov 11. Review.

PMID:
22079120
31.

Bile retinoids imprint intestinal CD103+ dendritic cells with the ability to generate gut-tropic T cells.

Jaensson-Gyllenbäck E, Kotarsky K, Zapata F, Persson EK, Gundersen TE, Blomhoff R, Agace WW.

Mucosal Immunol. 2011 Jul;4(4):438-47. doi: 10.1038/mi.2010.91. Epub 2011 Feb 2.

32.

The sensing of environmental stimuli by follicular dendritic cells promotes immunoglobulin A generation in the gut.

Suzuki K, Maruya M, Kawamoto S, Sitnik K, Kitamura H, Agace WW, Fagarasan S.

Immunity. 2010 Jul 23;33(1):71-83. doi: 10.1016/j.immuni.2010.07.003.

33.

The diverse ontogeny and function of murine small intestinal dendritic cell/macrophage subsets.

Persson EK, Jaensson E, Agace WW.

Immunobiology. 2010 Sep-Oct;215(9-10):692-7. doi: 10.1016/j.imbio.2010.05.013. Epub 2010 Jun 4. Review.

PMID:
20580119
34.

Intestinal CD103+, but not CX3CR1+, antigen sampling cells migrate in lymph and serve classical dendritic cell functions.

Schulz O, Jaensson E, Persson EK, Liu X, Worbs T, Agace WW, Pabst O.

J Exp Med. 2009 Dec 21;206(13):3101-14. doi: 10.1084/jem.20091925. Epub 2009 Dec 14.

35.

A novel role for constitutively expressed epithelial-derived chemokines as antibacterial peptides in the intestinal mucosa.

Kotarsky K, Sitnik KM, Stenstad H, Kotarsky H, Schmidtchen A, Koslowski M, Wehkamp J, Agace WW.

Mucosal Immunol. 2010 Jan;3(1):40-8. doi: 10.1038/mi.2009.115. Epub 2009 Oct 7.

PMID:
19812544
36.

The survival of memory CD4+ T cells within the gut lamina propria requires OX40 and CD30 signals.

Withers DR, Jaensson E, Gaspal F, McConnell FM, Eksteen B, Anderson G, Agace WW, Lane PJL.

J Immunol. 2009 Oct 15;183(8):5079-84. doi: 10.4049/jimmunol.0901514. Epub 2009 Sep 28.

37.

Chemokine CXCL13 is essential for lymph node initiation and is induced by retinoic acid and neuronal stimulation.

van de Pavert SA, Olivier BJ, Goverse G, Vondenhoff MF, Greuter M, Beke P, Kusser K, Höpken UE, Lipp M, Niederreither K, Blomhoff R, Sitnik K, Agace WW, Randall TD, de Jonge WJ, Mebius RE.

Nat Immunol. 2009 Nov;10(11):1193-9. doi: 10.1038/ni.1789. Epub 2009 Sep 27.

38.

Retinoic acid receptor signaling levels and antigen dose regulate gut homing receptor expression on CD8+ T cells.

Svensson M, Johansson-Lindbom B, Zapata F, Jaensson E, Austenaa LM, Blomhoff R, Agace WW.

Mucosal Immunol. 2008 Jan;1(1):38-48. doi: 10.1038/mi.2007.4.

39.

T-cell recruitment to the intestinal mucosa.

Agace WW.

Trends Immunol. 2008 Nov;29(11):514-22. doi: 10.1016/j.it.2008.08.003. Review.

PMID:
18838302
40.

Small intestinal CD103+ dendritic cells display unique functional properties that are conserved between mice and humans.

Jaensson E, Uronen-Hansson H, Pabst O, Eksteen B, Tian J, Coombes JL, Berg PL, Davidsson T, Powrie F, Johansson-Lindbom B, Agace WW.

J Exp Med. 2008 Sep 1;205(9):2139-49. doi: 10.1084/jem.20080414. Epub 2008 Aug 18.

41.

IL-10-dependent partial refractoriness to Toll-like receptor stimulation modulates gut mucosal dendritic cell function.

Monteleone I, Platt AM, Jaensson E, Agace WW, Mowat AM.

Eur J Immunol. 2008 Jun;38(6):1533-47. doi: 10.1002/eji.200737909.

42.

Involvement of CCR9 at multiple stages of adult T lymphopoiesis.

Svensson M, Marsal J, Uronen-Hansson H, Cheng M, Jenkinson W, Cilio C, Jacobsen SE, Sitnicka E, Anderson G, Agace WW.

J Leukoc Biol. 2008 Jan;83(1):156-64. Epub 2007 Oct 2.

PMID:
17911179
43.

Chemokine receptor expression defines heterogeneity in the earliest thymic migrants.

Jenkinson WE, Rossi SW, Parnell SM, Agace WW, Takahama Y, Jenkinson EJ, Anderson G.

Eur J Immunol. 2007 Aug;37(8):2090-6.

44.

Differential homing mechanisms regulate regionalized effector CD8alphabeta+ T cell accumulation within the small intestine.

Stenstad H, Svensson M, Cucak H, Kotarsky K, Agace WW.

Proc Natl Acad Sci U S A. 2007 Jun 12;104(24):10122-7. Epub 2007 Jun 5.

45.

Critical role of FLT3 ligand in IL-7 receptor independent T lymphopoiesis and regulation of lymphoid-primed multipotent progenitors.

Sitnicka E, Buza-Vidas N, Ahlenius H, Cilio CM, Gekas C, Nygren JM, Månsson R, Cheng M, Jensen CT, Svensson M, Leandersson K, Agace WW, Sigvardsson M, Jacobsen SE.

Blood. 2007 Oct 15;110(8):2955-64. Epub 2007 May 31.

PMID:
17540845
46.

Generation of gut-homing T cells and their localization to the small intestinal mucosa.

Johansson-Lindbom B, Agace WW.

Immunol Rev. 2007 Feb;215:226-42. Review.

PMID:
17291292
47.

Role of CCL25/CCR9 in immune homeostasis and disease.

Svensson M, Agace WW.

Expert Rev Clin Immunol. 2006 Sep;2(5):759-73. doi: 10.1586/1744666X.2.5.759.

PMID:
20477631
48.

Tissue-tropic effector T cells: generation and targeting opportunities.

Agace WW.

Nat Rev Immunol. 2006 Sep;6(9):682-92. Review.

PMID:
16932753
49.

Gut-associated lymphoid tissue-primed CD4+ T cells display CCR9-dependent and -independent homing to the small intestine.

Stenstad H, Ericsson A, Johansson-Lindbom B, Svensson M, Marsal J, Mack M, Picarella D, Soler D, Marquez G, Briskin M, Agace WW.

Blood. 2006 May 1;107(9):3447-54. Epub 2006 Jan 3.

PMID:
16391017
50.

Functional specialization of gut CD103+ dendritic cells in the regulation of tissue-selective T cell homing.

Johansson-Lindbom B, Svensson M, Pabst O, Palmqvist C, Marquez G, Förster R, Agace WW.

J Exp Med. 2005 Oct 17;202(8):1063-73. Epub 2005 Oct 10.

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