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Items: 1 to 50 of 70

1.

Integrated pan-cancer map of EBV-associated neoplasms reveals functional host-virus interactions.

Chakravorty S, Yan B, Wang C, Wang L, Quaid JT, Lin CF, Briggs SD, Majumder J, Canaria DA, Chauss D, Chopra G, Olson MR, Zhao B, Afzali B, Kazemian M.

Cancer Res. 2019 Sep 3. pii: canres.0615.2019. doi: 10.1158/0008-5472.CAN-19-0615. [Epub ahead of print]

PMID:
31481499
2.

Human retinoic acid-regulated CD161+ regulatory T cells support wound repair in intestinal mucosa.

Povoleri GAM, Nova-Lamperti E, Scottà C, Fanelli G, Chen YC, Becker PD, Boardman D, Costantini B, Romano M, Pavlidis P, McGregor R, Pantazi E, Chauss D, Sun HW, Shih HY, Cousins DJ, Cooper N, Powell N, Kemper C, Pirooznia M, Laurence A, Kordasti S, Kazemian M, Lombardi G, Afzali B.

Nat Immunol. 2018 Dec;19(12):1403-1414. doi: 10.1038/s41590-018-0230-z. Epub 2018 Nov 5.

3.

Complement receptor CD46 co-stimulates optimal human CD8+ T cell effector function via fatty acid metabolism.

Arbore G, West EE, Rahman J, Le Friec G, Niyonzima N, Pirooznia M, Tunc I, Pavlidis P, Powell N, Li Y, Liu P, Servais A, Couzi L, Fremeaux-Bacchi V, Placais L, Ferraro A, Walsh PR, Kavanagh D, Afzali B, Lavender P, Lachmann HJ, Kemper C.

Nat Commun. 2018 Oct 10;9(1):4186. doi: 10.1038/s41467-018-06706-z.

4.

Unexpected Roles for Intracellular Complement in the Regulation of Th1 Responses.

West EE, Afzali B, Kemper C.

Adv Immunol. 2018;138:35-70. doi: 10.1016/bs.ai.2018.02.001. Epub 2018 Mar 26. Review.

PMID:
29731006
5.

STAT5B: A Differential Regulator of the Life and Death of CD4+ Effector Memory T Cells.

Majri SS, Fritz JM, Villarino AV, Zheng L, Kanellopoulou C, Chaigne-Delalande B, Grönholm J, Niemela JE, Afzali B, Biancalana M, Pittaluga S, Sun A, Cohen JL, Holland SM, O'Shea JJ, Uzel G, Lenardo MJ.

J Immunol. 2018 Jan 1;200(1):110-118. doi: 10.4049/jimmunol.1701133. Epub 2017 Nov 29.

6.

BACH2 immunodeficiency illustrates an association between super-enhancers and haploinsufficiency.

Afzali B, Grönholm J, Vandrovcova J, O'Brien C, Sun HW, Vanderleyden I, Davis FP, Khoder A, Zhang Y, Hegazy AN, Villarino AV, Palmer IW, Kaufman J, Watts NR, Kazemian M, Kamenyeva O, Keith J, Sayed A, Kasperaviciute D, Mueller M, Hughes JD, Fuss IJ, Sadiyah MF, Montgomery-Recht K, McElwee J, Restifo NP, Strober W, Linterman MA, Wingfield PT, Uhlig HH, Roychoudhuri R, Aitman TJ, Kelleher P, Lenardo MJ, O'Shea JJ, Cooper N, Laurence ADJ.

Nat Immunol. 2017 Jul;18(7):813-823. doi: 10.1038/ni.3753. Epub 2017 May 22.

7.

Chronic Antibody-Mediated Rejection in Nonhuman Primate Renal Allografts: Validation of Human Histological and Molecular Phenotypes.

Adam BA, Smith RN, Rosales IA, Matsunami M, Afzali B, Oura T, Cosimi AB, Kawai T, Colvin RB, Mengel M.

Am J Transplant. 2017 Nov;17(11):2841-2850. doi: 10.1111/ajt.14327. Epub 2017 May 24.

8.

Anti-myeloperoxidase antibodies attenuate the monocyte response to LPS and shape macrophage development.

Popat RJ, Hakki S, Thakker A, Coughlan AM, Watson J, Little MA, Spickett CM, Lavender P, Afzali B, Kemper C, Robson MG.

JCI Insight. 2017 Jan 26;2(2):e87379. doi: 10.1172/jci.insight.87379.

9.

Molecular Assessment of Microcirculation Injury in Formalin-Fixed Human Cardiac Allograft Biopsies With Antibody-Mediated Rejection.

Afzali B, Chapman E, Racapé M, Adam B, Bruneval P, Gil F, Kim D, Hidalgo L, Campbell P, Sis B, Duong Van Huyen JP, Mengel M.

Am J Transplant. 2017 Feb;17(2):496-505. doi: 10.1111/ajt.13956. Epub 2016 Aug 2.

10.

T helper 1 immunity requires complement-driven NLRP3 inflammasome activity in CD4⁺ T cells.

Arbore G, West EE, Spolski R, Robertson AAB, Klos A, Rheinheimer C, Dutow P, Woodruff TM, Yu ZX, O'Neill LA, Coll RC, Sher A, Leonard WJ, Köhl J, Monk P, Cooper MA, Arno M, Afzali B, Lachmann HJ, Cope AP, Mayer-Barber KD, Kemper C.

Science. 2016 Jun 17;352(6292):aad1210. doi: 10.1126/science.aad1210.

11.

Signal transducer and activator of transcription 5 (STAT5) paralog dose governs T cell effector and regulatory functions.

Villarino A, Laurence A, Robinson GW, Bonelli M, Dema B, Afzali B, Shih HY, Sun HW, Brooks SR, Hennighausen L, Kanno Y, O'Shea JJ.

Elife. 2016 Mar 21;5. pii: e08384. doi: 10.7554/eLife.08384.

12.

Multiplexed color-coded probe-based gene expression assessment for clinical molecular diagnostics in formalin-fixed paraffin-embedded human renal allograft tissue.

Adam B, Afzali B, Dominy KM, Chapman E, Gill R, Hidalgo LG, Roufosse C, Sis B, Mengel M.

Clin Transplant. 2016 Mar;30(3):295-305. doi: 10.1111/ctr.12689. Epub 2016 Feb 3.

PMID:
26729350
13.

Impact of immunosuppressive drugs on the therapeutic efficacy of ex vivo expanded human regulatory T cells.

Scottà C, Fanelli G, Hoong SJ, Romano M, Lamperti EN, Sukthankar M, Guggino G, Fazekasova H, Ratnasothy K, Becker PD, Afzali B, Lechler RI, Lombardi G.

Haematologica. 2016 Jan;101(1):91-100. doi: 10.3324/haematol.2015.128934. Epub 2015 Oct 15.

14.

EZH2 is crucial for both differentiation of regulatory T cells and T effector cell expansion.

Yang XP, Jiang K, Hirahara K, Vahedi G, Afzali B, Sciume G, Bonelli M, Sun HW, Jankovic D, Kanno Y, Sartorelli V, O'Shea JJ, Laurence A.

Sci Rep. 2015 Jun 19;5:10643. doi: 10.1038/srep10643.

15.

Complement Regulates Nutrient Influx and Metabolic Reprogramming during Th1 Cell Responses.

Kolev M, Dimeloe S, Le Friec G, Navarini A, Arbore G, Povoleri GA, Fischer M, Belle R, Loeliger J, Develioglu L, Bantug GR, Watson J, Couzi L, Afzali B, Lavender P, Hess C, Kemper C.

Immunity. 2015 Jun 16;42(6):1033-47. doi: 10.1016/j.immuni.2015.05.024.

16.

Chemical Basis for Qualitative and Quantitative Differences Between ABO Blood Groups and Subgroups: Implications for Organ Transplantation.

Jeyakanthan M, Tao K, Zou L, Meloncelli PJ, Lowary TL, Suzuki K, Boland D, Larsen I, Burch M, Shaw N, Beddows K, Addonizio L, Zuckerman W, Afzali B, Kim DH, Mengel M, Shapiro AM, West LJ.

Am J Transplant. 2015 Oct;15(10):2602-15. doi: 10.1111/ajt.13328. Epub 2015 May 26.

17.

Developing in vitro expanded CD45RA+ regulatory T cells as an adoptive cell therapy for Crohn's disease.

Canavan JB, Scottà C, Vossenkämper A, Goldberg R, Elder MJ, Shoval I, Marks E, Stolarczyk E, Lo JW, Powell N, Fazekasova H, Irving PM, Sanderson JD, Howard JK, Yagel S, Afzali B, MacDonald TT, Hernandez-Fuentes MP, Shpigel NY, Lombardi G, Lord GM.

Gut. 2016 Apr;65(4):584-94. doi: 10.1136/gutjnl-2014-306919. Epub 2015 Feb 24.

18.

Regulatory T-cell therapy in the induction of transplant tolerance: the issue of subpopulations.

Edozie FC, Nova-Lamperti EA, Povoleri GA, Scottà C, John S, Lombardi G, Afzali B.

Transplantation. 2014 Aug 27;98(4):370-9. doi: 10.1097/TP.0000000000000243. Review.

PMID:
24933458
19.

Vitamin D in renal transplantation - from biological mechanisms to clinical benefits.

McGregor R, Li G, Penny H, Lombardi G, Afzali B, Goldsmith DJ.

Am J Transplant. 2014 Jun;14(6):1259-70. doi: 10.1111/ajt.12738. Epub 2014 May 19. Review.

20.

Intracellular complement activation sustains T cell homeostasis and mediates effector differentiation.

Liszewski MK, Kolev M, Le Friec G, Leung M, Bertram PG, Fara AF, Subias M, Pickering MC, Drouet C, Meri S, Arstila TP, Pekkarinen PT, Ma M, Cope A, Reinheckel T, Rodriguez de Cordoba S, Afzali B, Atkinson JP, Kemper C.

Immunity. 2013 Dec 12;39(6):1143-57. doi: 10.1016/j.immuni.2013.10.018. Epub 2013 Dec 5.

21.

Regulatory T cells in renal cell carcinoma: additional fuel to the bonfire of debate.

Afzali B, Lombardi G.

BJU Int. 2013 Sep;112(5):538-9. doi: 10.1111/bju.12190. No abstract available.

22.

Thymic versus induced regulatory T cells - who regulates the regulators?

Povoleri GA, Scottà C, Nova-Lamperti EA, John S, Lombardi G, Afzali B.

Front Immunol. 2013 Jun 27;4:169. doi: 10.3389/fimmu.2013.00169. Print 2013.

23.

CD161 expression characterizes a subpopulation of human regulatory T cells that produces IL-17 in a STAT3-dependent manner.

Afzali B, Mitchell PJ, Edozie FC, Povoleri GA, Dowson SE, Demandt L, Walter G, Canavan JB, Scotta C, Menon B, Chana PS, Khamri W, Kordasti SY, Heck S, Grimbacher B, Tree T, Cope AP, Taams LS, Lechler RI, John S, Lombardi G.

Eur J Immunol. 2013 Aug;43(8):2043-54. doi: 10.1002/eji.201243296. Epub 2013 Jul 3.

24.

Comparison of regulatory T cells in hemodialysis patients and healthy controls: implications for cell therapy in transplantation.

Afzali B, Edozie FC, Fazekasova H, Scottà C, Mitchell PJ, Canavan JB, Kordasti SY, Chana PS, Ellis R, Lord GM, John S, Hilton R, Lechler RI, Lombardi G.

Clin J Am Soc Nephrol. 2013 Aug;8(8):1396-405. doi: 10.2215/CJN.12931212. Epub 2013 Apr 11.

25.

Microtensile bond strength of self-etch adhesives in different surface conditionings.

Sohrabi A, Amini M, Afzali BM, Ghasemi A, Sohrabi A, Vahidpakdel SM.

Eur J Paediatr Dent. 2012 Dec;13(4):317-20.

PMID:
23270291
26.

Assessment of regulatory T-cell function in forthcoming clinical trials of cell therapy.

Canavan JB, Afzali B, Lord GM, Lombardi G.

Expert Rev Mol Diagn. 2013 Jan;13(1):5-7. doi: 10.1586/erm.12.133. No abstract available.

27.

Differential effects of rapamycin and retinoic acid on expansion, stability and suppressive qualities of human CD4(+)CD25(+)FOXP3(+) T regulatory cell subpopulations.

Scottà C, Esposito M, Fazekasova H, Fanelli G, Edozie FC, Ali N, Xiao F, Peakman M, Afzali B, Sagoo P, Lechler RI, Lombardi G.

Haematologica. 2013 Aug;98(8):1291-9. doi: 10.3324/haematol.2012.074088. Epub 2012 Dec 14.

28.

Helicobacter pylori induces in-vivo expansion of human regulatory T cells through stimulating interleukin-1β production by dendritic cells.

Mitchell PJ, Afzali B, Fazekasova H, Chen D, Ali N, Powell N, Lord GM, Lechler RI, Lombardi G.

Clin Exp Immunol. 2012 Dec;170(3):300-9. doi: 10.1111/j.1365-2249.2012.04659.x.

29.

A rapid diagnostic test for human regulatory T-cell function to enable regulatory T-cell therapy.

Canavan JB, Afzali B, Scottà C, Fazekasova H, Edozie FC, Macdonald TT, Hernandez-Fuentes MP, Lombardi G, Lord GM.

Blood. 2012 Feb 23;119(8):e57-66. doi: 10.1182/blood-2011-09-380048. Epub 2012 Jan 4.

30.

IL-2 regulates expression of C-MAF in human CD4 T cells.

Rani A, Afzali B, Kelly A, Tewolde-Berhan L, Hackett M, Kanhere AS, Pedroza-Pacheco I, Bowen H, Jurcevic S, Jenner RG, Cousins DJ, Ragheb JA, Lavender P, John S.

J Immunol. 2011 Oct 1;187(7):3721-9. doi: 10.4049/jimmunol.1002354. Epub 2011 Aug 29.

31.

Relative resistance of human CD4(+) memory T cells to suppression by CD4(+) CD25(+) regulatory T cells.

Afzali B, Mitchell PJ, Scottà C, Canavan J, Edozie FC, Fazekasova H, Lord GM, John S, Barber LD, Hernandez-Fuentes MP, Lechler RI, Lombardi G.

Am J Transplant. 2011 Aug;11(8):1734-42. doi: 10.1111/j.1600-6143.2011.03635.x. Epub 2011 Jul 12.

32.

Cell therapy to promote transplantation tolerance: a winning strategy?

Lombardi G, Sagoo P, Scotta C, Fazekasova H, Smyth L, Tsang J, Afzali B, Lechler R.

Immunotherapy. 2011 Apr;3(4 Suppl):28-31. doi: 10.2217/imt.11.42. Review.

PMID:
21524166
33.

T-cell alloimmunity and chronic allograft dysfunction.

Safinia N, Afzali B, Atalar K, Lombardi G, Lechler RI.

Kidney Int Suppl. 2010 Dec;(119):S2-12. doi: 10.1038/ki.2010.416. Review.

34.

Comparison of the efficacy of 5% topical spironolactone gel and placebo in the treatment of mild and moderate acne vulgaris: a randomized controlled trial.

Afzali BM, Yaghoobi E, Yaghoobi R, Bagherani N, Dabbagh MA.

J Dermatolog Treat. 2012 Feb;23(1):21-5. doi: 10.3109/09546634.2010.488260. Epub 2010 Oct 22.

PMID:
20964565
35.

Anti-TNFalpha therapy--killing two birds with one stone?

Arif S, Cox P, Afzali B, Lombardi G, Lechler RI, Peakman M, Mirenda V.

Lancet. 2010 Jun 26;375(9733):2278. doi: 10.1016/S0140-6736(10)60394-7. No abstract available.

PMID:
20609973
36.

Translational mini-review series on Th17 cells: induction of interleukin-17 production by regulatory T cells.

Afzali B, Mitchell P, Lechler RI, John S, Lombardi G.

Clin Exp Immunol. 2010 Feb;159(2):120-30. doi: 10.1111/j.1365-2249.2009.04038.x. Epub 2009 Nov 11. Review.

37.

Imbalance of effector and regulatory CD4 T cells is associated with graft-versus-host disease after hematopoietic stem cell transplantation using a reduced intensity conditioning regimen and alemtuzumab.

Matthews K, Lim Z, Afzali B, Pearce L, Abdallah A, Kordasti S, Pagliuca A, Lombardi G, Madrigal JA, Mufti GJ, Barber LD.

Haematologica. 2009 Jul;94(7):956-66. doi: 10.3324/haematol.2008.003103. Epub 2009 Jun 2.

38.

The T helper 17-regulatory T cell axis in transplant rejection and tolerance.

Mitchell P, Afzali B, Lombardi G, Lechler RI.

Curr Opin Organ Transplant. 2009 Aug;14(4):326-31. doi: 10.1097/MOT.0b013e32832ce88e. Review.

PMID:
19448538
39.

Relative roles of Th1 and Th17 effector cells in allograft rejection.

Atalar K, Afzali B, Lord G, Lombardi G.

Curr Opin Organ Transplant. 2009 Feb;14(1):23-9. doi: 10.1097/MOT.0b013e32831b70c2. Review.

PMID:
19337142
40.

IL-17-producing CD4(+) T cells, pro-inflammatory cytokines and apoptosis are increased in low risk myelodysplastic syndrome.

Kordasti SY, Afzali B, Lim Z, Ingram W, Hayden J, Barber L, Matthews K, Chelliah R, Guinn B, Lombardi G, Farzaneh F, Mufti GJ.

Br J Haematol. 2009 Apr;145(1):64-72. doi: 10.1111/j.1365-2141.2009.07593.x. Epub 2009 Feb 3.

PMID:
19210506
41.

Pathways of major histocompatibility complex allorecognition.

Afzali B, Lombardi G, Lechler RI.

Curr Opin Organ Transplant. 2008 Aug;13(4):438-44. doi: 10.1097/MOT.0b013e328309ee31. Review.

42.

Long-term risks of increased use of intravenous iron.

Afzali B, Goldsmith DJ.

Lancet. 2007 Aug 11;370(9586):482; author reply 482-3. No abstract available.

PMID:
17693171
43.

Falls, hypokalaemia, and a dry mouth.

Atalar K, Afzali B, Lams B, Tungekar MF, Goldsmith DJ.

Lancet. 2007 Jul 14;370(9582):192. doi: 10.1016/S0140-6736(07)61093-9. No abstract available.

PMID:
17630043
44.

The maintenance of human CD4+ CD25+ regulatory T cell function: IL-2, IL-4, IL-7 and IL-15 preserve optimal suppressive potency in vitro.

Yates J, Rovis F, Mitchell P, Afzali B, Tsang J, Garin M, Lechler RI, Lombardi G, Garden OA.

Int Immunol. 2007 Jun;19(6):785-99. Epub 2007 Jun 1.

PMID:
17545278
45.

Intercellular transfer of MHC and immunological molecules: molecular mechanisms and biological significance.

Smyth LA, Afzali B, Tsang J, Lombardi G, Lechler RI.

Am J Transplant. 2007 Jun;7(6):1442-9. Review.

46.

Allorecognition and the alloresponse: clinical implications.

Afzali B, Lechler RI, Hernandez-Fuentes MP.

Tissue Antigens. 2007 Jun;69(6):545-56. Review.

PMID:
17498264
47.

CD4+CD25high Foxp3+ regulatory T cells in myelodysplastic syndrome (MDS).

Kordasti SY, Ingram W, Hayden J, Darling D, Barber L, Afzali B, Lombardi G, Wlodarski MW, Maciejewski JP, Farzaneh F, Mufti GJ.

Blood. 2007 Aug 1;110(3):847-50. Epub 2007 Apr 5.

PMID:
17412885
48.

The role of T helper 17 (Th17) and regulatory T cells (Treg) in human organ transplantation and autoimmune disease.

Afzali B, Lombardi G, Lechler RI, Lord GM.

Clin Exp Immunol. 2007 Apr;148(1):32-46. Review.

49.

Diabetes, kidney disease and anaemia: time to tackle a troublesome triad?

Al-Khoury S, Afzali B, Shah N, Thomas S, Gusbeth-Tatomir P, Goldsmith D, Covic A.

Int J Clin Pract. 2007 Feb;61(2):281-9. Review.

PMID:
17263715
50.

Bleeding post coronary artery bypass surgery. Clopidogrel--cure or culprit?

Haydar AA, Abchee AB, El-Hajj II, Hujairi NM, Tfaili AS, Hatoum T, Quateen A, Bakri R, Afzali B, Goldsmith DJ.

J Med Liban. 2006 Jan-Mar;54(1):11-6.

PMID:
17044627

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