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Items: 37


Molecular epidemiology, genetic variability and evolution of HTLV-1 with special emphasis on African genotypes.

Afonso PV, Cassar O, Gessain A.

Retrovirology. 2019 Dec 16;16(1):39. doi: 10.1186/s12977-019-0504-z. Review.


Absence of accessory genes in a divergent simian T-lymphotropic virus type 1 isolated from a bonnet macaque (Macaca radiata).

Afonso PV, Fagrouch Z, Deijs M, Niphuis H, Bogers W, Gessain A, van der Hoek L, Verschoor EJ.

PLoS Negl Trop Dis. 2019 Jul 8;13(7):e0007521. doi: 10.1371/journal.pntd.0007521. eCollection 2019 Jul.


Proteomic analysis of plasma extracellular vesicles reveals mitochondrial stress upon HTLV-1 infection.

Jeannin P, Chaze T, Giai Gianetto Q, Matondo M, Gout O, Gessain A, Afonso PV.

Sci Rep. 2018 Mar 26;8(1):5170. doi: 10.1038/s41598-018-23505-0.


Original Chemical Series of Pyrimidine Biosynthesis Inhibitors That Boost the Antiviral Interferon Response.

Lucas-Hourani M, Dauzonne D, Munier-Lehmann H, Khiar S, Nisole S, Dairou J, Helynck O, Afonso PV, Tangy F, Vidalain PO.

Antimicrob Agents Chemother. 2017 Sep 22;61(10). pii: e00383-17. doi: 10.1128/AAC.00383-17. Print 2017 Oct.


HTLV-1-induced leukotriene B4 secretion by T cells promotes T cell recruitment and virus propagation.

Percher F, Curis C, Pérès E, Artesi M, Rosewick N, Jeannin P, Gessain A, Gout O, Mahieux R, Ceccaldi PE, Van den Broeke A, Duc Dodon M, Afonso PV.

Nat Commun. 2017 Jun 22;8:15890. doi: 10.1038/ncomms15890.


HTLV-1 and host barriers interactions.

Percher F, Vidy A, Gessain A, Ceccaldi PE, Afonso PV.

Virologie (Montrouge). 2017 Feb 1;21(1):11-18. doi: 10.1684/vir.2016.0675.


Human T-Lymphotropic Virus Type 1-Induced Overexpression of Activated Leukocyte Cell Adhesion Molecule (ALCAM) Facilitates Trafficking of Infected Lymphocytes through the Blood-Brain Barrier.

Curis C, Percher F, Jeannin P, Montange T, Chevalier SA, Seilhean D, Cartier L, Couraud PO, Gout O, Gessain A, Ceccaldi PE, Afonso PV.

J Virol. 2016 Jul 27;90(16):7303-7312. doi: 10.1128/JVI.00539-16. Print 2016 Aug 15.


Mother-to-Child Transmission of HTLV-1 Epidemiological Aspects, Mechanisms and Determinants of Mother-to-Child Transmission.

Percher F, Jeannin P, Martin-Latil S, Gessain A, Afonso PV, Vidy-Roche A, Ceccaldi PE.

Viruses. 2016 Feb 3;8(2). pii: E40. doi: 10.3390/v8020040. Review.


Cocirculation of Two env Molecular Variants, of Possible Recombinant Origin, in Gorilla and Chimpanzee Simian Foamy Virus Strains from Central Africa.

Richard L, Rua R, Betsem E, Mouinga-Ondémé A, Kazanji M, Leroy E, Njouom R, Buseyne F, Afonso PV, Gessain A.

J Virol. 2015 Dec;89(24):12480-91. doi: 10.1128/JVI.01798-15. Epub 2015 Oct 7.


Northern African strains of human T-lymphotropic virus type 1 arose from a recombination event.

Desrames A, Cassar O, Gout O, Hermine O, Taylor GP, Afonso PV, Gessain A.

J Virol. 2014 Sep 1;88(17):9782-8. doi: 10.1128/JVI.01591-14. Epub 2014 Jun 18.


Human T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein.

Jaworski E, Narayanan A, Van Duyne R, Shabbeer-Meyering S, Iordanskiy S, Saifuddin M, Das R, Afonso PV, Sampey GC, Chung M, Popratiloff A, Shrestha B, Sehgal M, Jain P, Vertes A, Mahieux R, Kashanchi F.

J Biol Chem. 2014 Aug 8;289(32):22284-305. doi: 10.1074/jbc.M114.549659. Epub 2014 Jun 17.


Epidemiology and genetic variability of HHV-8/KSHV in Pygmy and Bantu populations in Cameroon.

Betsem E, Cassar O, Afonso PV, Fontanet A, Froment A, Gessain A.

PLoS Negl Trop Dis. 2014 May 15;8(5):e2851. doi: 10.1371/journal.pntd.0002851. eCollection 2014 May.


Gem-induced cytoskeleton remodeling increases cellular migration of HTLV-1-infected cells, formation of infected-to-target T-cell conjugates and viral transmission.

Chevalier SA, Turpin J, Cachat A, Afonso PV, Gessain A, Brady JN, Pise-Masison CA, Mahieux R.

PLoS Pathog. 2014 Feb 27;10(2):e1003917. doi: 10.1371/journal.ppat.1003917. eCollection 2014 Feb.


Molecular epidemiology of merkel cell polyomavirus: evidence for geographically related variant genotypes.

Martel-Jantin C, Filippone C, Tortevoye P, Afonso PV, Betsem E, Descorps-Declere S, Nicol JT, Touzé A, Coursaget P, Crouzat M, Berthet N, Cassar O, Gessain A.

J Clin Microbiol. 2014 May;52(5):1687-90. doi: 10.1128/JCM.02348-13. Epub 2014 Feb 12.


[Leukotriene B(4): a lipid at the heart of inflammation].

Afonso PV, Parent CA.

Med Sci (Paris). 2013 Dec;29(12):1083-5. doi: 10.1051/medsci/20132912007. Epub 2013 Dec 20. French. No abstract available.


Human T-cell lymphotropic virus type 1 subtype C molecular variants among indigenous australians: new insights into the molecular epidemiology of HTLV-1 in Australo-Melanesia.

Cassar O, Einsiedel L, Afonso PV, Gessain A.

PLoS Negl Trop Dis. 2013 Sep 26;7(9):e2418. doi: 10.1371/journal.pntd.0002418. eCollection 2013.


Neutrophil swarms require LTB4 and integrins at sites of cell death in vivo.

Lämmermann T, Afonso PV, Angermann BR, Wang JM, Kastenmüller W, Parent CA, Germain RN.

Nature. 2013 Jun 20;498(7454):371-5. doi: 10.1038/nature12175. Epub 2013 May 26.


Discoidin domain receptor 2 regulates neutrophil chemotaxis in 3D collagen matrices.

Afonso PV, McCann CP, Kapnick SM, Parent CA.

Blood. 2013 Feb 28;121(9):1644-50. doi: 10.1182/blood-2012-08-451575. Epub 2012 Dec 11.


LTB4 is a signal-relay molecule during neutrophil chemotaxis.

Afonso PV, Janka-Junttila M, Lee YJ, McCann CP, Oliver CM, Aamer KA, Losert W, Cicerone MT, Parent CA.

Dev Cell. 2012 May 15;22(5):1079-91. doi: 10.1016/j.devcel.2012.02.003. Epub 2012 Apr 26.


Blood-brain barrier and retroviral infections.

Miller F, Afonso PV, Gessain A, Ceccaldi PE.

Virulence. 2012 Mar-Apr;3(2):222-9. doi: 10.4161/viru.19697. Epub 2012 Mar 1. Review.


Neutrophils under tension.

Afonso PV, Parent CA.

Dev Cell. 2012 Feb 14;22(2):236-8. doi: 10.1016/j.devcel.2012.01.017.


PI3K and chemotaxis: a priming issue?

Afonso PV, Parent CA.

Sci Signal. 2011 Apr 26;4(170):pe22. doi: 10.1126/scisignal.2002019. Review.


HTLV-2B strains, similar to those found in several Amerindian tribes, are endemic in central African Bakola Pygmies.

Mauclère P, Afonso PV, Meertens L, Plancoulaine S, Calattini S, Froment A, Van Beveren M, de Thé G, Quintana-Murci L, Mahieux R, Gessain A.

J Infect Dis. 2011 May 1;203(9):1316-23. doi: 10.1093/infdis/jir031.


Highly active antiretroviral treatment against STLV-1 infection combining reverse transcriptase and HDAC inhibitors.

Afonso PV, Mekaouche M, Mortreux F, Toulza F, Moriceau A, Wattel E, Gessain A, Bangham CR, Dubreuil G, Plumelle Y, Hermine O, Estaquier J, Mahieux R.

Blood. 2010 Nov 11;116(19):3802-8. doi: 10.1182/blood-2010-02-270751. Epub 2010 Jun 29.


NRP/Optineurin Cooperates with TAX1BP1 to potentiate the activation of NF-kappaB by human T-lymphotropic virus type 1 tax protein.

Journo C, Filipe J, About F, Chevalier SA, Afonso PV, Brady JN, Flynn D, Tangy F, Israël A, Vidalain PO, Mahieux R, Weil R.

PLoS Pathog. 2009 Jul;5(7):e1000521. doi: 10.1371/journal.ppat.1000521. Epub 2009 Jul 17.


The receptor complex associated with human T-cell lymphotropic virus type 3 (HTLV-3) Env-mediated binding and entry is distinct from, but overlaps with, the receptor complexes of HTLV-1 and HTLV-2.

Jones KS, Huang YK, Chevalier SA, Afonso PV, Petrow-Sadowski C, Bertolette DC, Gessain A, Ruscetti FW, Mahieux R.

J Virol. 2009 May;83(10):5244-55. doi: 10.1128/JVI.02285-08. Epub 2009 Mar 11.


Alteration of blood-brain barrier integrity by retroviral infection.

Afonso PV, Ozden S, Cumont MC, Seilhean D, Cartier L, Rezaie P, Mason S, Lambert S, Huerre M, Gessain A, Couraud PO, Pique C, Ceccaldi PE, Romero IA.

PLoS Pathog. 2008 Nov;4(11):e1000205. doi: 10.1371/journal.ppat.1000205. Epub 2008 Nov 14.


Primary cardiac angiosarcoma. Extended resection of the right atrial wall. Case report.

Afonso PV, Antunes MJ.

Rev Port Cardiol. 2007 Nov;26(11):1189-94. English, Portuguese.


Human herpesvirus-8 (HHV-8)-associated primary effusion lymphoma in two renal transplant recipients receiving rapamycin.

Boulanger E, Afonso PV, Yahiaoui Y, Adle-Biassette H, Gabarre J, Agbalika F.

Am J Transplant. 2008 Mar;8(3):707-10. doi: 10.1111/j.1600-6143.2007.02110.x. Epub 2008 Feb 5.


Right atrial aneurysm: case report.

Afonso PV, Antrunes MJ.

Rev Port Cardiol. 2007 Oct;26(10):1049-52. English, Portuguese.


Novel human herpesvirus 8 subtype D strains in Vanuatu, Melanesia.

Cassar O, Afonso PV, Bassot S, Plancoulaine S, Duprez R, Capuano C, Abel M, Martin PM, Gessain A.

Emerg Infect Dis. 2007 Nov;13(11):1745-8. doi: 10.3201/eid1311.070636.


Extracavitary tumor after primary effusion lymphoma: relapse or second distinct lymphoma?

Boulanger E, Meignin V, Afonso PV, Duprez R, Oksenhendler E, Agbalika F, Gessain A.

Haematologica. 2007 Sep;92(9):1275-6.


Human blood-brain barrier disruption by retroviral-infected lymphocytes: role of myosin light chain kinase in endothelial tight-junction disorganization.

Afonso PV, Ozden S, Prevost MC, Schmitt C, Seilhean D, Weksler B, Couraud PO, Gessain A, Romero IA, Ceccaldi PE.

J Immunol. 2007 Aug 15;179(4):2576-83.


Human T lymphotropic virus type 1 subtype C melanesian genetic variants of the Vanuatu Archipelago and Solomon Islands share a common ancestor.

Cassar O, Capuano C, Bassot S, Charavay F, Duprez R, Afonso PV, Abel M, Walter H, Mera W, Martin PM, Chungue E, Gessain A.

J Infect Dis. 2007 Aug 15;196(4):510-21. Epub 2007 Jun 28.


Characterization of reemerging chikungunya virus.

Sourisseau M, Schilte C, Casartelli N, Trouillet C, Guivel-Benhassine F, Rudnicka D, Sol-Foulon N, Le Roux K, Prevost MC, Fsihi H, Frenkiel MP, Blanchet F, Afonso PV, Ceccaldi PE, Ozden S, Gessain A, Schuffenecker I, Verhasselt B, Zamborlini A, Saïb A, Rey FA, Arenzana-Seisdedos F, Desprès P, Michault A, Albert ML, Schwartz O.

PLoS Pathog. 2007 Jun;3(6):e89.


Human muscle satellite cells as targets of Chikungunya virus infection.

Ozden S, Huerre M, Riviere JP, Coffey LL, Afonso PV, Mouly V, de Monredon J, Roger JC, El Amrani M, Yvin JL, Jaffar MC, Frenkiel MP, Sourisseau M, Schwartz O, Butler-Browne G, Desprès P, Gessain A, Ceccaldi PE.

PLoS One. 2007 Jun 13;2(6):e527.


Centrosome and retroviruses: the dangerous liaisons.

Afonso PV, Zamborlini A, Saïb A, Mahieux R.

Retrovirology. 2007 Apr 14;4:27. Review.

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