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Items: 1 to 50 of 153

1.

Origin and phylogenetic status of the local Ashanti Dwarf pig (ADP) of Ghana based on genetic analysis.

Osei-Amponsah R, Skinner BM, Adjei DO, Bauer J, Larson G, Affara NA, Sargent CA.

BMC Genomics. 2017 Feb 20;18(1):193. doi: 10.1186/s12864-017-3536-6.

2.

The pig X and Y Chromosomes: structure, sequence, and evolution.

Skinner BM, Sargent CA, Churcher C, Hunt T, Herrero J, Loveland JE, Dunn M, Louzada S, Fu B, Chow W, Gilbert J, Austin-Guest S, Beal K, Carvalho-Silva D, Cheng W, Gordon D, Grafham D, Hardy M, Harley J, Hauser H, Howden P, Howe K, Lachani K, Ellis PJ, Kelly D, Kerry G, Kerwin J, Ng BL, Threadgold G, Wileman T, Wood JM, Yang F, Harrow J, Affara NA, Tyler-Smith C.

Genome Res. 2016 Jan;26(1):130-9. doi: 10.1101/gr.188839.114. Epub 2015 Nov 11.

3.

Expansion of the HSFY gene family in pig lineages : HSFY expansion in suids.

Skinner BM, Lachani K, Sargent CA, Yang F, Ellis P, Hunt T, Fu B, Louzada S, Churcher C, Tyler-Smith C, Affara NA.

BMC Genomics. 2015 Jun 9;16:442. doi: 10.1186/s12864-015-1650-x.

4.

Impact on offspring methylation patterns of maternal gestational diabetes mellitus and intrauterine growth restraint suggest common genes and pathways linked to subsequent type 2 diabetes risk.

Quilter CR, Cooper WN, Cliffe KM, Skinner BM, Prentice PM, Nelson L, Bauer J, Ong KK, Constância M, Lowe WL, Affara NA, Dunger DB.

FASEB J. 2014 Nov;28(11):4868-79. doi: 10.1096/fj.14-255240. Epub 2014 Aug 21.

PMID:
25145626
5.

Thrifty metabolic programming in rats is induced by both maternal undernutrition and postnatal leptin treatment, but masked in the presence of both: implications for models of developmental programming.

Ellis PJ, Morris TJ, Skinner BM, Sargent CA, Vickers MH, Gluckman PD, Gilmour S, Affara NA.

BMC Genomics. 2014 Jan 21;15:49. doi: 10.1186/1471-2164-15-49.

6.

Genome wide analysis reveals single nucleotide polymorphisms associated with fatness and putative novel copy number variants in three pig breeds.

Fowler KE, Pong-Wong R, Bauer J, Clemente EJ, Reitter CP, Affara NA, Waite S, Walling GA, Griffin DK.

BMC Genomics. 2013 Nov 13;14:784. doi: 10.1186/1471-2164-14-784.

7.

Regions of XY homology in the pig X chromosome and the boundary of the pseudoautosomal region.

Skinner BM, Lachani K, Sargent CA, Affara NA.

BMC Genet. 2013 Jan 15;14:3. doi: 10.1186/1471-2156-14-3.

8.

A genetic basis for a postmeiotic X versus Y chromosome intragenomic conflict in the mouse.

Cocquet J, Ellis PJ, Mahadevaiah SK, Affara NA, Vaiman D, Burgoyne PS.

PLoS Genet. 2012 Sep;8(9):e1002900. doi: 10.1371/journal.pgen.1002900. Epub 2012 Sep 13.

9.

An association and haplotype analysis of porcine maternal infanticide: a model for human puerperal psychosis?

Quilter CR, Sargent CA, Bauer J, Bagga MR, Reiter CP, Hutchinson EL, Southwood OI, Evans G, Mileham A, Griffin DK, Affara NA.

Am J Med Genet B Neuropsychiatr Genet. 2012 Dec;159B(8):908-27. doi: 10.1002/ajmg.b.32097. Epub 2012 Sep 13.

PMID:
22976950
10.

The polymorphism analysis of CD169 and CD163 related with the risk of porcine reproductive and respiratory syndrome virus (PRRSV) infection.

Ren YW, Zhang YY, Affara NA, Sargent CA, Yang LG, Zhao JL, Fang LR, Wu JJ, Fang R, Tong Q, Xiao J, Li JL, Jiang YB, Chen HC, Zhang SJ.

Mol Biol Rep. 2012 Nov;39(11):9903-9. Epub 2012 Jun 28.

PMID:
22740140
11.

Association of multi-pathogenic infections with BAT2, CXCL12, Mx1 and EHMT2 variations in pigs.

Wang SJ, Liu WJ, Yang LG, Liu HB, Sargent CA, Affara NA, Zhang SJ.

Mol Biol Rep. 2012 Aug;39(8):8169-76. doi: 10.1007/s11033-012-1664-2. Epub 2012 Apr 25.

PMID:
22531939
12.

Periconceptional maternal micronutrient supplementation is associated with widespread gender related changes in the epigenome: a study of a unique resource in the Gambia.

Khulan B, Cooper WN, Skinner BM, Bauer J, Owens S, Prentice AM, Belteki G, Constancia M, Dunger D, Affara NA.

Hum Mol Genet. 2012 May 1;21(9):2086-101. doi: 10.1093/hmg/dds026. Epub 2012 Feb 3.

PMID:
22307237
13.

DNA methylation profiling at imprinted loci after periconceptional micronutrient supplementation in humans: results of a pilot randomized controlled trial.

Cooper WN, Khulan B, Owens S, Elks CE, Seidel V, Prentice AM, Belteki G, Ong KK, Affara NA, Constância M, Dunger DB.

FASEB J. 2012 May;26(5):1782-90. doi: 10.1096/fj.11-192708. Epub 2012 Jan 20.

PMID:
22267336
14.

Effects of FUT1 gene mutation on resistance to infectious disease.

Wang SJ, Liu WJ, Yang LG, Sargent CA, Liu HB, Wang C, Liu XD, Zhao SH, Affara NA, Liang AX, Zhang SJ.

Mol Biol Rep. 2012 Mar;39(3):2805-10. doi: 10.1007/s11033-011-1039-0. Epub 2011 Jun 22.

PMID:
21695432
15.

Effects of the polymorphisms of Mx1, BAT2 and CXCL12 genes on immunological traits in pigs.

Wang SJ, Liu WJ, Sargent CA, Zhao SH, Liu HB, Liu XD, Wang C, Hua GH, Yang LG, Affara NA, Zhang SJ.

Mol Biol Rep. 2012 Mar;39(3):2417-27. doi: 10.1007/s11033-011-0992-y. Epub 2011 Jun 12.

PMID:
21667240
16.

Association of Sly with sex-linked gene amplification during mouse evolution: a side effect of genomic conflict in spermatids?

Ellis PJ, Bacon J, Affara NA.

Hum Mol Genet. 2011 Aug 1;20(15):3010-21. doi: 10.1093/hmg/ddr204. Epub 2011 May 6.

PMID:
21551453
17.

An algorithm for determining the origin of trisomy and the positions of chiasmata from SNP genotype data.

Gabriel AS, Hassold TJ, Thornhill AR, Affara NA, Handyside AH, Griffin DK.

Chromosome Res. 2011 Feb;19(2):155-63. doi: 10.1007/s10577-010-9181-4. Epub 2011 Jan 12.

PMID:
21225334
18.

Deficiency in the multicopy Sycp3-like X-linked genes Slx and Slxl1 causes major defects in spermatid differentiation.

Cocquet J, Ellis PJ, Yamauchi Y, Riel JM, Karacs TP, Rattigan A, Ojarikre OA, Affara NA, Ward MA, Burgoyne PS.

Mol Biol Cell. 2010 Oct 15;21(20):3497-505. doi: 10.1091/mbc.E10-07-0601. Epub 2010 Aug 25.

19.

Analysis of X chromosome genomic DNA sequence copy number variation associated with premature ovarian failure (POF).

Quilter CR, Karcanias AC, Bagga MR, Duncan S, Murray A, Conway GS, Sargent CA, Affara NA.

Hum Reprod. 2010 Aug;25(8):2139-50. doi: 10.1093/humrep/deq158. Epub 2010 Jun 22.

20.

The human RPS4 paralogue on Yq11.223 encodes a structurally conserved ribosomal protein and is preferentially expressed during spermatogenesis.

Lopes AM, Miguel RN, Sargent CA, Ellis PJ, Amorim A, Affara NA.

BMC Mol Biol. 2010 May 7;11:33. doi: 10.1186/1471-2199-11-33.

21.
22.

Transcriptional changes in response to X chromosome dosage in the mouse: implications for X inactivation and the molecular basis of Turner Syndrome.

Lopes AM, Burgoyne PS, Ojarikre A, Bauer J, Sargent CA, Amorim A, Affara NA.

BMC Genomics. 2010 Feb 1;11:82. doi: 10.1186/1471-2164-11-82.

23.

Global transcriptional response of pig brain and lung to natural infection by Pseudorabies virus.

Yuan JF, Zhang SJ, Jafer O, Furlong RA, Chausiaux OE, Sargent CA, Zhang GH, Affara NA.

BMC Microbiol. 2009 Dec 1;9:246. doi: 10.1186/1471-2180-9-246.

24.

The multicopy gene Sly represses the sex chromosomes in the male mouse germline after meiosis.

Cocquet J, Ellis PJ, Yamauchi Y, Mahadevaiah SK, Affara NA, Ward MA, Burgoyne PS.

PLoS Biol. 2009 Nov;7(11):e1000244. doi: 10.1371/journal.pbio.1000244. Epub 2009 Nov 17.

25.

Association analysis between pseudorabies antibody and five single-nucleotide polymorphisms in pigs.

Zhang SJ, Jafer O, Yuan JF, Chen HC, Sargent CA, Wu B, Zhou R, Yang LG, Liu H, Wu JJ, Liu HB, Tong Q, Yu Y, Affara NA.

Animal. 2009 Oct;3(10):1363-7. doi: 10.1017/S1751731109004856.

PMID:
22444930
26.

Design of a high density SNP genotyping assay in the pig using SNPs identified and characterized by next generation sequencing technology.

Ramos AM, Crooijmans RP, Affara NA, Amaral AJ, Archibald AL, Beever JE, Bendixen C, Churcher C, Clark R, Dehais P, Hansen MS, Hedegaard J, Hu ZL, Kerstens HH, Law AS, Megens HJ, Milan D, Nonneman DJ, Rohrer GA, Rothschild MF, Smith TP, Schnabel RD, Van Tassell CP, Taylor JF, Wiedmann RT, Schook LB, Groenen MA.

PLoS One. 2009 Aug 5;4(8):e6524. doi: 10.1371/journal.pone.0006524.

27.

Mapping of 12 porcine fatness candidate genes in known fatness QTL based on human syntenies.

Yusuf M, Musilova P, Kubickova S, Rubes J, Zhang SJ, Affara NA, Sargent CA, Griffin DK.

Anim Genet. 2009 Aug;40(4):579-80. doi: 10.1111/j.1365-2052.2009.01878.x. Epub 2009 Apr 20. No abstract available.

PMID:
19397513
28.

Two novel mouse genes mapped to chromosome Yp are expressed specifically in spermatids.

Ferguson L, Ellis PJ, Affara NA.

Mamm Genome. 2009 Apr;20(4):193-206. doi: 10.1007/s00335-009-9175-8. Epub 2009 Mar 24.

PMID:
19308643
29.

Sex ratio bias in early-dead embryos of chickens collected during the first week of incubation.

Li WM, Feng YP, Zhao RX, Fan YZ, Affara NA, Wu JJ, Fang J, Tong Q, Wang C, Zhang SJ.

Poult Sci. 2008 Nov;87(11):2231-3. doi: 10.3382/ps.2008-00139.

PMID:
18931172
30.

Gene expression profiling in porcine maternal infanticide: a model for puerperal psychosis.

Quilter CR, Gilbert CL, Oliver GL, Jafer O, Furlong RA, Blott SC, Wilson AE, Sargent CA, Mileham A, Affara NA.

Am J Med Genet B Neuropsychiatr Genet. 2008 Oct 5;147B(7):1126-37. doi: 10.1002/ajmg.b.30734.

PMID:
18361432
31.

Association of four new single-nucleotide polymorphisms in follicle-stimulating hormone receptor and zona pellucida glycoprotein with reproductive traits in pigs.

Yuan JF, Jafer O, Affara NA, Gong YZ, Yang LG, Liu J, Moaeen-Ud-Din M, Li WM, Zhang SJ.

Animal. 2007 Oct;1(9):1249-53. doi: 10.1017/S1751731107000651.

PMID:
22444880
32.

Bidirectional transcription of a novel chimeric gene mapping to mouse chromosome Yq.

Ellis PJ, Ferguson L, Clemente EJ, Affara NA.

BMC Evol Biol. 2007 Sep 24;7:171.

33.

Hypogonadal mouse, a model to study the effects of the endogenous lack of gonadotropins on apoptosis.

Chausiaux OE, Abel MH, Baxter FO, Khaled WT, Ellis PJ, Charlton HM, Affara NA.

Biol Reprod. 2008 Jan;78(1):77-90. Epub 2007 Aug 1.

PMID:
17671269
34.

Identification of mutations of zona pellucida glycoprotein (ZP3) and its association with pig reproductive traits.

Yuan JF, Moaeen-ud-Din M, Gong YZ, Peng XL, Yang LG, Feng YP, Liu J, Hu B, Affara NA, Jafer O, Zhang SJ.

J Anim Breed Genet. 2007 Jun;124(3):144-9.

PMID:
17550356
35.

Porcine maternal infanticide as a model for puerperal psychosis.

Quilter CR, Blott SC, Wilson AE, Bagga MR, Sargent CA, Oliver GL, Southwood OI, Gilbert CL, Mileham A, Affara NA.

Am J Med Genet B Neuropsychiatr Genet. 2007 Oct 5;144B(7):862-8.

PMID:
17503476
36.

Coordinated transcriptional regulation patterns associated with infertility phenotypes in men.

Ellis PJ, Furlong RA, Conner SJ, Kirkman-Brown J, Afnan M, Barratt C, Griffin DK, Affara NA.

J Med Genet. 2007 Aug;44(8):498-508. Epub 2007 May 11.

37.

Analysis of sex chromosome abnormalities using X and Y chromosome DNA tiling path arrays.

Karcanias AC, Ichimura K, Mitchell MJ, Sargent CA, Affara NA.

J Med Genet. 2007 Jul;44(7):429-36. Epub 2007 Feb 27.

38.

Transcript profiles of some developmentally important genes detected in bovine oocytes and in vitro-produced blastocysts using RNA amplification and cDNA microarrays.

Mamo S, Sargent CA, Affara NA, Tesfaye D, El-Halawany N, Wimmers K, Gilles M, Schellander K, Ponsuksili S.

Reprod Domest Anim. 2006 Dec;41(6):527-34.

PMID:
17107512
39.

Gene expression study in the juvenile mouse testis: identification of stage-specific molecular pathways during spermatogenesis.

Clemente EJ, Furlong RA, Loveland KL, Affara NA.

Mamm Genome. 2006 Sep;17(9):956-75. Epub 2006 Sep 8.

PMID:
16964443
40.

Spermatogenesis and sex chromosome gene content: an evolutionary perspective.

Ellis PJ, Affara NA.

Hum Fertil (Camb). 2006 Mar;9(1):1-7.

PMID:
16581716
41.

Identification of novel Y chromosome encoded transcripts by testis transcriptome analysis of mice with deletions of the Y chromosome long arm.

Touré A, Clemente EJ, Ellis P, Mahadevaiah SK, Ojarikre OA, Ball PA, Reynard L, Loveland KL, Burgoyne PS, Affara NA.

Genome Biol. 2005;6(12):R102. Epub 2005 Dec 2.

42.

Deletions on mouse Yq lead to upregulation of multiple X- and Y-linked transcripts in spermatids.

Ellis PJ, Clemente EJ, Ball P, Touré A, Ferguson L, Turner JM, Loveland KL, Affara NA, Burgoyne PS.

Hum Mol Genet. 2005 Sep 15;14(18):2705-15. Epub 2005 Aug 8.

PMID:
16087683
43.

Resource and hardware options for microarray-based experimentation.

Affara NA.

Brief Funct Genomic Proteomic. 2003 Apr;2(1):7-20. Review.

PMID:
15239939
44.

A comparative analysis of the pig, mouse, and human PCDHX genes.

Blanco-Arias P, Sargent CA, Affara NA.

Mamm Genome. 2004 Apr;15(4):296-306.

PMID:
15112107
45.

Modulation of the mouse testis transcriptome during postnatal development and in selected models of male infertility.

Ellis PJ, Furlong RA, Wilson A, Morris S, Carter D, Oliver G, Print C, Burgoyne PS, Loveland KL, Affara NA.

Mol Hum Reprod. 2004 Apr;10(4):271-81. Epub 2004 Mar 2.

PMID:
14996999
46.

The role of the Y chromosome in male infertility.

Affara NA.

Expert Rev Mol Med. 2001 Jan 3;2001:1-16. No abstract available.

PMID:
14987368
47.

Sperm-induced modification of the oviductal gene expression profile after natural insemination in mice.

Fazeli A, Affara NA, Hubank M, Holt WV.

Biol Reprod. 2004 Jul;71(1):60-5. Epub 2004 Feb 18.

PMID:
14973272
48.
49.
50.

A mapping and evolutionary study of porcine sex chromosome genes.

Quilter CR, Blott SC, Mileham AJ, Affara NA, Sargent CA, Griffin DK.

Mamm Genome. 2002 Oct;13(10):588-94.

PMID:
12420137

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