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Items: 5


Loss of MAP3K7 Sensitizes Prostate Cancer Cells to CDK1/2 Inhibition and DNA Damage by Disrupting Homologous Recombination.

Washino S, Rider LC, Romero L, Jillson LK, Affandi T, Ohm AM, Lam ET, Reyland ME, Costello JC, Cramer SD.

Mol Cancer Res. 2019 Oct;17(10):1985-1998. doi: 10.1158/1541-7786.MCR-18-1335. Epub 2019 Jul 12.


EGF receptor and PKCδ kinase activate DNA damage-induced pro-survival and pro-apoptotic signaling via biphasic activation of ERK and MSK1 kinases.

Ohm AM, Affandi T, Reyland ME.

J Biol Chem. 2019 Mar 22;294(12):4488-4497. doi: 10.1074/jbc.RA118.006944. Epub 2019 Jan 24.


Mechanism of metal ion-induced activation of a two-component sensor kinase.

Affandi T, McEvoy MM.

Biochem J. 2019 Jan 15;476(1):115-135. doi: 10.1042/BCJ20180577.


The Structure of the Periplasmic Sensor Domain of the Histidine Kinase CusS Shows Unusual Metal Ion Coordination at the Dimeric Interface.

Affandi T, Issaian AV, McEvoy MM.

Biochemistry. 2016 Sep 20;55(37):5296-306. doi: 10.1021/acs.biochem.6b00707. Epub 2016 Sep 12.


N-terminal region of CusB is sufficient for metal binding and metal transfer with the metallochaperone CusF.

Mealman TD, Zhou M, Affandi T, Chacón KN, Aranguren ME, Blackburn NJ, Wysocki VH, McEvoy MM.

Biochemistry. 2012 Aug 28;51(34):6767-75. Epub 2012 Aug 17.

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