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Items: 1 to 50 of 745

1.

Pathways to resilience: adapting to sea level rise in Los Angeles.

Aerts JCJH, Barnard PL, Botzen W, Grifman P, Hart JF, De Moel H, Mann AN, de Ruig LT, Sadrpour N.

Ann N Y Acad Sci. 2018 Sep;1427(1):1-90. doi: 10.1111/nyas.13917.

PMID:
30230554
2.

Renal impairment during pemetrexed maintenance in patients with advanced non-small-cell lung cancer: a cohort study.

Visser S, Huisbrink J, van 't Veer NE, van Toor JJ, van Boxem AJM, van Walree NC, Stricker BH, Aerts JGJV.

Eur Respir J. 2018 Aug 23. pii: 1800884. doi: 10.1183/13993003.00884-2018. [Epub ahead of print]

PMID:
30139775
3.

Excessive dietary lipid intake provokes an acquired form of lysosomal lipid storage disease in the kidney.

Rampanelli E, Ochodnicky P, Vissers JPC, Butter LM, Claessen N, Calcagni A, Kors L, Gethings LA, Bakker SJL, de Borst MH, Navis GJ, Liebisch G, Speijer D, van den Bergh Weerman MA, Jung B, Aten J, Steenbergen E, Schmitz G, Ballabio A, Florquin S, Aerts JMFG, Leemans JC.

J Pathol. 2018 Aug 2. doi: 10.1002/path.5150. [Epub ahead of print]

PMID:
30073645
4.

Chemical Proteomic Analysis of Serine Hydrolase Activity in Niemann-Pick Type C Mouse Brain.

van Rooden EJ, van Esbroeck ACM, Baggelaar MP, Deng H, Florea BI, Marques ARA, Ottenhoff R, Boot RG, Overkleeft HS, Aerts JMFG, van der Stelt M.

Front Neurosci. 2018 Jul 3;12:440. doi: 10.3389/fnins.2018.00440. eCollection 2018.

5.

Locoregional control and survival after lymph node SBRT in oligometastatic disease.

Loi M, Frelinghuysen M, Klass ND, Oomen-De Hoop E, Granton PV, Aerts J, Verhoef C, Nuyttens J.

Clin Exp Metastasis. 2018 Jul 11. doi: 10.1007/s10585-018-9922-x. [Epub ahead of print]

PMID:
29995254
6.

Disentangling the role of TRPM4 in hippocampus-dependent plasticity and learning: an electrophysiological, behavioral and FMRI approach.

Bovet-Carmona M, Menigoz A, Pinto S, Tambuyzer T, Krautwald K, Voets T, Aerts JM, Angenstein F, Vennekens R, Balschun D.

Brain Struct Funct. 2018 Jul 3. doi: 10.1007/s00429-018-1706-1. [Epub ahead of print]

PMID:
29971514
7.

Collagen Degradation and Formation Are Elevated in Exacerbated COPD Compared With Stable Disease.

Schumann DM, Leeming D, Papakonstantinou E, Blasi F, Kostikas K, Boersma W, Louis R, Milenkovic B, Aerts J, Sand JMB, Wouters EFM, Rohde G, Prat C, Torres A, Welte T, Tamm M, Karsdal M, Stolz D.

Chest. 2018 Jun 30. pii: S0012-3692(18)30980-2. doi: 10.1016/j.chest.2018.06.028. [Epub ahead of print]

PMID:
29966667
8.

High-throughput image-based monitoring of cell aggregation and microspheroid formation.

Deckers T, Lambrechts T, Viazzi S, Nilsson Hall G, Papantoniou I, Bloemen V, Aerts JM.

PLoS One. 2018 Jun 28;13(6):e0199092. doi: 10.1371/journal.pone.0199092. eCollection 2018.

9.

Immune checkpoint blockade therapy of mesothelioma: a clinical and radiological challenge.

Calabrò L, Morra A, Cornelissen R, Aerts J, Maio M.

Cancer Immunol Immunother. 2018 Aug;67(8):1317-1324. doi: 10.1007/s00262-018-2191-3. Epub 2018 Jun 26. Review.

PMID:
29943157
10.

Potential of memory T cells in bridging preoperative chemoradiation and immunotherapy in rectal cancer.

de Mey S, Jiang H, Wang H, Engels B, Gevaert T, Dufait I, Feron O, Aerts J, Verovski V, De Ridder M.

Radiother Oncol. 2018 Jun;127(3):361-369. doi: 10.1016/j.radonc.2018.04.003. Epub 2018 Jun 2. Review.

PMID:
29871814
11.

Potential Molecular Signatures Predictive of Lung Cancer Brain Metastasis.

Pedrosa RMSM, Mustafa DAM, Aerts JGJV, Kros JM.

Front Oncol. 2018 May 11;8:159. doi: 10.3389/fonc.2018.00159. eCollection 2018. Review.

12.

Modulation of Innate Immune-Related Genes and Glucocorticoid Synthesis in Gnotobiotic Full-Sibling European Sea Bass (Dicentrarchus labrax) Larvae Challenged With Vibrio anguillarum.

Reyes-López FE, Aerts J, Vallejos-Vidal E, Ampe B, Dierckens K, Tort L, Bossier P.

Front Immunol. 2018 May 8;9:914. doi: 10.3389/fimmu.2018.00914. eCollection 2018.

13.

Biomarkers in malignant mesothelioma-an unfulfilled need or a waste of resources?

Cornelissen R, Aerts JGJV.

J Thorac Dis. 2018 Apr;10(Suppl 9):S1084-S1087. doi: 10.21037/jtd.2018.03.128. No abstract available.

14.

Spiro-epoxyglycosides as Activity-Based Probes for Glycoside Hydrolase Family 99 Endomannosidase/Endomannanase.

Schröder SP, Kallemeijn WW, Debets MF, Hansen T, Sobala LF, Hakki Z, Williams SJ, Beenakker TJM, Aerts JMFG, van der Marel GA, Codée JDC, Davies GJ, Overkleeft HS.

Chemistry. 2018 Jul 11;24(39):9983-9992. doi: 10.1002/chem.201801902. Epub 2018 Jun 21.

15.

Publisher Correction: Using high-amplitude and focused transcranial alternating current stimulation to entrain physiological tremor.

Khatoun A, Breukers J, Op de Beeck S, Nica IG, Aerts JM, Seynaeve L, Haeck T, Asamoah B, Mc Laughlin M.

Sci Rep. 2018 May 23;8(1):8221. doi: 10.1038/s41598-018-26013-3.

16.
17.

Treatment Satisfaction of Patients With Advanced Non-Small-cell Lung Cancer Receiving Platinum-based Chemotherapy: Results From a Prospective Cohort Study (PERSONAL).

Visser S, de Mol M, Cheung K, van Toor JJ, van Walree NC, Stricker BH, Den Oudsten BL, Aerts JGJV.

Clin Lung Cancer. 2018 Jul;19(4):e503-e516. doi: 10.1016/j.cllc.2018.03.003. Epub 2018 Mar 17.

PMID:
29705017
18.

Association between single-nucleotide polymorphisms and adverse events in nivolumab-treated non-small cell lung cancer patients.

Bins S, Basak EA, El Bouazzaoui S, Koolen SLW, Oomen-de Hoop E, van der Leest CH, van der Veldt AAM, Sleijfer S, Debets R, van Schaik RHN, Aerts JGJV, Mathijssen RHJ.

Br J Cancer. 2018 May;118(10):1296-1301. doi: 10.1038/s41416-018-0074-1. Epub 2018 Apr 26.

PMID:
29695768
19.

Nicotiana benthamiana α-galactosidase A1.1 can functionally complement human α-galactosidase A deficiency associated with Fabry disease.

Kytidou K, Beekwilder J, Artola M, van Meel E, Wilbers RHP, Moolenaar GF, Goosen N, Ferraz MJ, Katzy R, Voskamp P, Florea BI, Hokke CH, Overkleeft HS, Schots A, Bosch D, Pannu N, Aerts JMFG.

J Biol Chem. 2018 Jun 29;293(26):10042-10058. doi: 10.1074/jbc.RA118.001774. Epub 2018 Apr 19.

PMID:
29674318
20.

Do wild-caught urban house sparrows show desensitized stress responses to a novel stressor?

Salleh Hudin N, Teyssier A, Aerts J, Fairhurst GD, Strubbe D, White J, De Neve L, Lens L.

Biol Open. 2018 Jun 15;7(6). pii: bio031849. doi: 10.1242/bio.031849.

21.

Escalating impacts of climate extremes on critical infrastructures in Europe.

Forzieri G, Bianchi A, Silva FBE, Marin Herrera MA, Leblois A, Lavalle C, Aerts JCJH, Feyen L.

Glob Environ Change. 2018 Jan;48:97-107. doi: 10.1016/j.gloenvcha.2017.11.007.

22.

Heterogeneity in Immune Cell Content in Malignant Pleural Mesothelioma.

Minnema-Luiting J, Vroman H, Aerts J, Cornelissen R.

Int J Mol Sci. 2018 Mar 30;19(4). pii: E1041. doi: 10.3390/ijms19041041. Review.

23.

Gluco-1 H-imidazole: A New Class of Azole-Type β-Glucosidase Inhibitor.

Schröder SP, Wu L, Artola M, Hansen T, Offen WA, Ferraz MJ, Li KY, Aerts JMFG, van der Marel GA, Codée JDC, Davies GJ, Overkleeft HS.

J Am Chem Soc. 2018 Apr 18;140(15):5045-5048. doi: 10.1021/jacs.8b02399. Epub 2018 Apr 4.

24.

Using high-amplitude and focused transcranial alternating current stimulation to entrain physiological tremor.

Khatoun A, Breukers J, Op de Beeck S, Nica IG, Aerts JM, Seynaeve L, Haeck T, Asamoah B, Mc Laughlin M.

Sci Rep. 2018 Mar 21;8(1):4927. doi: 10.1038/s41598-018-23290-w. Erratum in: Sci Rep. 2018 May 23;8(1):8221.

25.

IFNΛ3/4 locus polymorphisms and IFNΛ3 circulating levels are associated with COPD severity and outcomes.

Egli A, Mandal J, Schumann DM, Roth M, Thomas B, Lorne Tyrrell D, Blasi F, Kostikas K, Boersma W, Milenkovic B, Lacoma A, Rentsch K, Rohde GGU, Louis R, Aerts JG, Welte T, Torres A, Tamm M, Stolz D.

BMC Pulm Med. 2018 Mar 21;18(1):51. doi: 10.1186/s12890-018-0616-6.

26.

Erratum: Conceptualization and validation of an open-source closed-loop deep brain stimulation system in rat.

Wu H, Ghekiere H, Beeckmans D, Tambuyzer T, van Kuyck K, Aerts JM, Nuttin B.

Sci Rep. 2018 Mar 19;8:46954. doi: 10.1038/srep46954.

27.

Factors affecting local control of pulmonary oligometastases treated with stereotactic body radiotherapy.

Sharma A, Duijm M, Oomen-de Hoop E, Aerts JG, Verhoef C, Hoogeman M, Nuyttens JJ.

Acta Oncol. 2018 Aug;57(8):1031-1037. doi: 10.1080/0284186X.2018.1445285. Epub 2018 Feb 28.

PMID:
29488414
28.

Immune checkpoint blockade combined with IL-6 and TGF-β inhibition improves the therapeutic outcome of mRNA-based immunotherapy.

Bialkowski L, Van der Jeught K, Bevers S, Tjok Joe P, Renmans D, Heirman C, Aerts JL, Thielemans K.

Int J Cancer. 2018 Aug 1;143(3):686-698. doi: 10.1002/ijc.31331. Epub 2018 Mar 13.

PMID:
29464699
29.

HEPES activates a MiT/TFE-dependent lysosomal-autophagic gene network in cultured cells: A call for caution.

Tol MJ, van der Lienden MJC, Gabriel TL, Hagen JJ, Scheij S, Veenendaal T, Klumperman J, Donker-Koopman WE, Verhoeven AJ, Overkleeft H, Aerts JM, Argmann CA, van Eijk M.

Autophagy. 2018;14(3):437-449. doi: 10.1080/15548627.2017.1419118. Epub 2018 Feb 17.

30.

Immunotherapy: a new standard of care in thoracic malignancies? A summary of the European Respiratory Society research seminar of the Thoracic Oncology Assembly.

Costantini A, Grynovska M, Lucibello F, Moisés J, Pagès F, Tsao MS, Shepherd FA, Bouchaab H, Garassino M, Aerts JGJV, Mazières J, Mondini M, Berghmans T, Meert AP, Cadranel J.

Eur Respir J. 2018 Feb 14;51(2). pii: 1702072. doi: 10.1183/13993003.02072-2017. Print 2018 Feb.

PMID:
29444918
31.

Dendritic cell immunotherapy followed by cART interruption during HIV-1 infection induces plasma protein markers of cellular immunity and neutrophil recruitment.

van den Ham HJ, Cooper JD, Tomasik J, Bahn S, Aerts JL, Osterhaus ADME, Gruters RA, Andeweg AC; DC-TRN trial investigators.

PLoS One. 2018 Feb 1;13(2):e0192278. doi: 10.1371/journal.pone.0192278. eCollection 2018.

32.

Silver Nanoparticles Impair Retinoic Acid-Inducible Gene I-Mediated Mitochondrial Antiviral Immunity by Blocking the Autophagic Flux in Lung Epithelial Cells.

Villeret B, Dieu A, Straube M, Solhonne B, Miklavc P, Hamadi S, Le Borgne R, Mailleux A, Norel X, Aerts J, Diallo D, Rouzet F, Dietl P, Sallenave JM, Garcia-Verdugo I.

ACS Nano. 2018 Feb 27;12(2):1188-1202. doi: 10.1021/acsnano.7b06934. Epub 2018 Jan 30.

PMID:
29357226
33.

Automated Assessment of Endpoint and Kinematic Features of Skilled Reaching in Rats.

Nica I, Deprez M, Nuttin B, Aerts JM.

Front Behav Neurosci. 2018 Jan 4;11:255. doi: 10.3389/fnbeh.2017.00255. eCollection 2017.

34.

Treatment selection of early stage non-small cell lung cancer: the role of the patient in clinical decision making.

Mokhles S, Nuyttens JJME, de Mol M, Aerts JGJV, Maat APWM, Birim Ö, Bogers AJJC, Takkenberg JJM.

BMC Cancer. 2018 Jan 15;18(1):79. doi: 10.1186/s12885-018-3986-5.

35.

Activity-Based Probes for Glycosidases: Profiling and Other Applications.

Kuo CL, van Meel E, Kytidou K, Kallemeijn WW, Witte M, Overkleeft HS, Artola ME, Aerts JM.

Methods Enzymol. 2018;598:217-235. doi: 10.1016/bs.mie.2017.06.039. Epub 2017 Dec 8.

PMID:
29306436
36.

Ethnic differences in metabolite signatures and type 2 diabetes: a nested case-control analysis among people of South Asian, African and European origin.

van Valkengoed IGM, Argmann C, Ghauharali-van der Vlugt K, Aerts JMFG, Brewster LM, Peters RJG, Vaz FM, Houtkooper RH.

Nutr Diabetes. 2017 Dec 19;7(12):300. doi: 10.1038/s41387-017-0003-z.

37.

Oxygen saturation measurements in telemonitoring of patients with COPD: a systematic review.

Buekers J, De Boever P, Vaes AW, Aerts JM, Wouters EFM, Spruit MA, Theunis J.

Expert Rev Respir Med. 2018 Feb;12(2):113-123. doi: 10.1080/17476348.2018.1417842. Epub 2017 Dec 20.

PMID:
29241369
38.

Autologous Dendritic Cells Pulsed with Allogeneic Tumor Cell Lysate in Mesothelioma: From Mouse to Human.

Aerts JGJV, de Goeje PL, Cornelissen R, Kaijen-Lambers MEH, Bezemer K, van der Leest CH, Mahaweni NM, Kunert A, Eskens FALM, Waasdorp C, Braakman E, van der Holt B, Vulto AG, Hendriks RW, Hegmans JPJJ, Hoogsteden HC.

Clin Cancer Res. 2018 Feb 15;24(4):766-776. doi: 10.1158/1078-0432.CCR-17-2522. Epub 2017 Dec 12.

PMID:
29233904
39.

Thrombolytic therapy based on fucoidan-functionalized polymer nanoparticles targeting P-selectin.

Juenet M, Aid-Launais R, Li B, Berger A, Aerts J, Ollivier V, Nicoletti A, Letourneur D, Chauvierre C.

Biomaterials. 2018 Feb;156:204-216. doi: 10.1016/j.biomaterials.2017.11.047. Epub 2017 Nov 29.

PMID:
29216534
40.

Silicone Wristband Passive Samplers Yield Highly Individualized Pesticide Residue Exposure Profiles.

Aerts R, Joly L, Szternfeld P, Tsilikas K, De Cremer K, Castelain P, Aerts JM, Van Orshoven J, Somers B, Hendrickx M, Andjelkovic M, Van Nieuwenhuyse A.

Environ Sci Technol. 2018 Jan 2;52(1):298-307. doi: 10.1021/acs.est.7b05039. Epub 2017 Dec 13.

PMID:
29185731
41.

Insights into Flood-Coping Appraisals of Protection Motivation Theory: Empirical Evidence from Germany and France.

Bubeck P, Wouter Botzen WJ, Laudan J, Aerts JCJH, Thieken AH.

Risk Anal. 2018 Jun;38(6):1239-1257. doi: 10.1111/risa.12938. Epub 2017 Nov 17.

PMID:
29148082
42.

Measuring brain synaptic vesicle protein 2A with positron emission tomography and [18F]UCB-H.

Bahri MA, Plenevaux A, Aerts J, Bastin C, Becker G, Mercier J, Valade A, Buchanan T, Mestdagh N, Ledoux D, Seret A, Luxen A, Salmon E.

Alzheimers Dement (N Y). 2017 Aug 30;3(4):481-486. doi: 10.1016/j.trci.2017.08.004. eCollection 2017 Nov.

43.

Towards broad spectrum activity-based glycosidase probes: synthesis and evaluation of deoxygenated cyclophellitol aziridines.

Schröder SP, van de Sande JW, Kallemeijn WW, Kuo CL, Artola M, van Rooden EJ, Jiang J, Beenakker TJM, Florea BI, Offen WA, Davies GJ, Minnaard AJ, Aerts JMFG, Codée JDC, van der Marel GA, Overkleeft HS.

Chem Commun (Camb). 2017 Nov 21;53(93):12528-12531. doi: 10.1039/c7cc07730k.

PMID:
29116266
44.

Treatment with long acting muscarinic antagonists stimulates serum levels of irisin in patients with COPD.

Mandal J, Roth M, Papakonstantinou E, Sun Q, Costa L, Boeck L, Scherr A, Rakic J, Louis R, Milenkovic B, Boersma W, Kostikas K, Blasi F, Aerts J, Rohde G, Lacoma A, Torres A, Welte T, Tamm M, Stolz D.

Pulm Pharmacol Ther. 2018 Feb;48:111-116. doi: 10.1016/j.pupt.2017.10.011. Epub 2017 Oct 21.

PMID:
29066215
45.

In situ visualization of glucocerebrosidase in human skin tissue: zymography versus activity-based probe labeling.

van Smeden J, Dijkhoff IM, Helder RWJ, Al-Khakany H, Boer DEC, Schreuder A, Kallemeijn WW, Absalah S, Overkleeft HS, Aerts JMFG, Bouwstra JA.

J Lipid Res. 2017 Dec;58(12):2299-2309. doi: 10.1194/jlr.M079376. Epub 2017 Oct 12.

PMID:
29025868
46.

SCENIC: single-cell regulatory network inference and clustering.

Aibar S, González-Blas CB, Moerman T, Huynh-Thu VA, Imrichova H, Hulselmans G, Rambow F, Marine JC, Geurts P, Aerts J, van den Oord J, Atak ZK, Wouters J, Aerts S.

Nat Methods. 2017 Nov;14(11):1083-1086. doi: 10.1038/nmeth.4463. Epub 2017 Oct 9.

47.

High and individually variable enzymatic activity precludes accurate determination of pemetrexed, methotrexate and their polyglutamate metabolite concentrations in plasma.

Stoop MP, Visser S, van Dijk E, Aerts JGJV, Stricker BH, Luider TM.

J Pharm Biomed Anal. 2018 Jan 30;148:89-92. doi: 10.1016/j.jpba.2017.09.014. Epub 2017 Sep 14.

PMID:
28965049
48.

A Fluorescence Polarization Activity-Based Protein Profiling Assay in the Discovery of Potent, Selective Inhibitors for Human Nonlysosomal Glucosylceramidase.

Lahav D, Liu B, van den Berg RJBHN, van den Nieuwendijk AMCH, Wennekes T, Ghisaidoobe AT, Breen I, Ferraz MJ, Kuo CL, Wu L, Geurink PP, Ovaa H, van der Marel GA, van der Stelt M, Boot RG, Davies GJ, Aerts JMFG, Overkleeft HS.

J Am Chem Soc. 2017 Oct 11;139(40):14192-14197. doi: 10.1021/jacs.7b07352. Epub 2017 Sep 29.

49.

Uniform and blinded cause of death verification of the NELSON lung cancer screening participants.

Yousaf-Khan AU, van der Aalst CM, Aerts JGJV, den Bakker MA, de Koning HJ.

Lung Cancer. 2017 Sep;111:131-134. doi: 10.1016/j.lungcan.2017.07.018. Epub 2017 Jul 22.

PMID:
28838383
50.

1,6-Cyclophellitol Cyclosulfates: A New Class of Irreversible Glycosidase Inhibitor.

Artola M, Wu L, Ferraz MJ, Kuo CL, Raich L, Breen IZ, Offen WA, Codée JDC, van der Marel GA, Rovira C, Aerts JMFG, Davies GJ, Overkleeft HS.

ACS Cent Sci. 2017 Jul 26;3(7):784-793. doi: 10.1021/acscentsci.7b00214. Epub 2017 Jul 13.

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