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Items: 1 to 50 of 766

1.

Induction of peripheral effector CD8 T cell proliferation by combination of paclitaxel, carboplatin and bevacizumab in non-small cell lung cancer patients.

de Goeje PL, Poncin M, Bezemer K, Kaijen-Lambers MEH, Groen HJ, Smit EF, Dingemans AC, Kunert A, Hendriks RW, Aerts JG.

Clin Cancer Res. 2019 Jan 14. pii: clincanres.2243.2018. doi: 10.1158/1078-0432.CCR-18-2243. [Epub ahead of print]

PMID:
30642911
2.

The clinical impact of pseudomonas aeruginosa eradication in bronchiectasis in a Dutch referral center.

Pieters A, Bakker M, Hoek RAS, Altenburg J, van Westreenen M, Aerts JGJV, van der Eerden MM.

Eur Respir J. 2019 Jan 11. pii: 1802081. doi: 10.1183/13993003.02081-2018. [Epub ahead of print] No abstract available.

PMID:
30635292
3.

In vivo inactivation of glycosidases by conduritol B epoxide and cyclophellitol as revealed by activity-based protein profiling.

Kuo CL, Kallemeijn WW, Lelieveld LT, Mirzaian M, Zoutendijk I, Vardi A, Futerman AH, Meijer AH, Spaink HP, Overkleeft HS, Aerts JMFG, Artola M.

FEBS J. 2019 Jan 1. doi: 10.1111/febs.14744. [Epub ahead of print]

PMID:
30600575
4.

Glycoprotein Non-Metastatic Protein B: An Emerging Biomarker for Lysosomal Dysfunction in Macrophages.

van der Lienden MJC, Gaspar P, Boot R, Aerts JMFG, van Eijk M.

Int J Mol Sci. 2018 Dec 24;20(1). pii: E66. doi: 10.3390/ijms20010066. Review.

5.

Combination Strategies to Optimize Efficacy of Dendritic Cell-Based Immunotherapy.

van Gulijk M, Dammeijer F, Aerts JGJV, Vroman H.

Front Immunol. 2018 Dec 5;9:2759. doi: 10.3389/fimmu.2018.02759. eCollection 2018. Review.

6.

Current State of Dendritic Cell-Based Immunotherapy: Opportunities for in vitro Antigen Loading of Different DC Subsets?

Huber A, Dammeijer F, Aerts JGJV, Vroman H.

Front Immunol. 2018 Dec 3;9:2804. doi: 10.3389/fimmu.2018.02804. eCollection 2018. Review.

7.

The American Society of Clinical Oncology-endorsed American Society for Radiation Oncology Evidence-Based Guideline of stereotactic body radiotherapy for early-stage non-small cell lung cancer: An expert opinion.

Guckenberger M, Aerts JG, Van Schil P, Weder W.

J Thorac Cardiovasc Surg. 2019 Jan;157(1):358-361. doi: 10.1016/j.jtcvs.2018.09.107. Epub 2018 Oct 12. No abstract available.

PMID:
30557952
8.

Low-dose cyclophosphamide depletes circulating naïve and activated regulatory T cells in malignant pleural mesothelioma patients synergistically treated with dendritic cell-based immunotherapy.

Noordam L, Kaijen MEH, Bezemer K, Cornelissen R, Maat LAPWM, Hoogsteden HC, Aerts JGJV, Hendriks RW, Hegmans JPJJ, Vroman H.

Oncoimmunology. 2018 Jul 30;7(12):e1474318. doi: 10.1080/2162402X.2018.1474318. eCollection 2018.

9.

The heat shock protein amplifier arimoclomol improves refolding, maturation and lysosomal activity of glucocerebrosidase.

Fog CK, Zago P, Malini E, Solanko LM, Peruzzo P, Bornaes C, Magnoni R, Mehmedbasic A, Petersen NHT, Bembi B, Aerts JFMG, Dardis A, Kirkegaard T.

EBioMedicine. 2018 Dec;38:142-153. doi: 10.1016/j.ebiom.2018.11.037. Epub 2018 Nov 27.

11.

GRNBoost2 and Arboreto: efficient and scalable inference of gene regulatory networks.

Moerman T, Aibar S, González-Blas CB, Simm J, Moreau Y, Aerts J, Aerts S.

Bioinformatics. 2018 Nov 15. doi: 10.1093/bioinformatics/bty916. [Epub ahead of print]

PMID:
30445495
12.

Circulating desmosine as a biomarker of azithromycin treatment response: a post hoc analysis of the COLUMBUS randomised controlled trial.

Chalmers JD, Djamin RS, Schouten M, Keir HR, Tan B, Aerts JGJV, Huang JT, van der Eerden M.

ERJ Open Res. 2018 Nov 12;4(4). pii: 00136-2018. doi: 10.1183/23120541.00136-2018. eCollection 2018 Oct.

13.

Financing agricultural drought risk through ex-ante cash transfers.

Guimarães Nobre G, Davenport F, Bischiniotis K, Veldkamp T, Jongman B, Funk CC, Husak G, Ward PJ, Aerts JCJH.

Sci Total Environ. 2018 Oct 31;653:523-535. doi: 10.1016/j.scitotenv.2018.10.406. [Epub ahead of print]

14.

Dissociation of globotriaosylceramide and impaired endothelial function in α-galactosidase-A deficient EA.hy926 cells.

Kaissarian N, Kang J, Shu L, Ferraz MJ, Aerts JM, Shayman JA.

Mol Genet Metab. 2018 Dec;125(4):338-344. doi: 10.1016/j.ymgme.2018.10.007. Epub 2018 Nov 2.

PMID:
30413389
15.

Quantification of a Glucocorticoid Profile in Non-pooled Samples Is Pivotal in Stress Research Across Vertebrates.

Aerts J.

Front Endocrinol (Lausanne). 2018 Oct 23;9:635. doi: 10.3389/fendo.2018.00635. eCollection 2018. Review.

16.

A chemical genetic screen reveals that iminosugar inhibitors of plant glucosylceramide synthase inhibit root growth in Arabidopsis and cereals.

Rugen MD, Vernet MMJL, Hantouti L, Soenens A, Andriotis VME, Rejzek M, Brett P, van den Berg RJBHN, Aerts JMFG, Overkleeft HS, Field RA.

Sci Rep. 2018 Nov 6;8(1):16421. doi: 10.1038/s41598-018-34749-1.

17.

New Irreversible α-l-Iduronidase Inhibitors and Activity-Based Probes.

Artola M, Kuo CL, McMahon SA, Oehler V, Hansen T, van der Lienden M, He X, van den Elst H, Florea BI, Kermode AR, van der Marel GA, Gloster TM, Codée JDC, Overkleeft HS, Aerts JMFG.

Chemistry. 2018 Dec 17;24(71):19081-19088. doi: 10.1002/chem.201804662. Epub 2018 Nov 26.

PMID:
30307091
18.

Survival and prognostic factors of pulmonary oligometastases treated with stereotactic body radiotherapy.

Sharma A, Duijm M, Oomen-de Hoop E, Aerts JG, Verhoef C, Hoogeman M, Nuyttens JJ.

Acta Oncol. 2018 Oct 3:1-7. doi: 10.1080/0284186X.2018.1521986. [Epub ahead of print]

PMID:
30280633
19.

Distinguishing the differences in β-glycosylceramidase folds, dynamics, and actions informs therapeutic uses.

Ben Bdira F, Artola M, Overkleeft HS, Ubbink M, Aerts JMFG.

J Lipid Res. 2018 Dec;59(12):2262-2276. doi: 10.1194/jlr.R086629. Epub 2018 Oct 2.

PMID:
30279220
20.

Correction: Do wild-caught urban house sparrows show desensitized stress responses to a novel stressor? (doi:10.1242/bio.031849).

Hudin NS, Teyssier A, Aerts J, Fairhurst GD, Strubbe D, White JL, De Neve L, Lens L.

Biol Open. 2018 Sep 28;7(9). pii: bio038513. doi: 10.1242/bio.038513. No abstract available.

21.

Autologous Dendritic Cell Therapy in Mesothelioma Patients Enhances Frequencies of Peripheral CD4 T Cells Expressing HLA-DR, PD-1, or ICOS.

de Goeje PL, Klaver Y, Kaijen-Lambers MEH, Langerak AW, Vroman H, Kunert A, Lamers CHJ, Aerts JGJV, Debets R, Hendriks RW.

Front Immunol. 2018 Sep 7;9:2034. doi: 10.3389/fimmu.2018.02034. eCollection 2018.

22.

Pathways to resilience: adapting to sea level rise in Los Angeles.

Aerts JCJH, Barnard PL, Botzen W, Grifman P, Hart JF, De Moel H, Mann AN, de Ruig LT, Sadrpour N.

Ann N Y Acad Sci. 2018 Sep;1427(1):1-90. doi: 10.1111/nyas.13917.

PMID:
30230554
23.

Renal impairment during pemetrexed maintenance in patients with advanced nonsmall cell lung cancer: a cohort study.

Visser S, Huisbrink J, van 't Veer NE, van Toor JJ, van Boxem AJM, van Walree NC, Stricker BH, Aerts JGJV.

Eur Respir J. 2018 Oct 25;52(4). pii: 1800884. doi: 10.1183/13993003.00884-2018. Print 2018 Oct.

PMID:
30139775
24.

Excessive dietary lipid intake provokes an acquired form of lysosomal lipid storage disease in the kidney.

Rampanelli E, Ochodnicky P, Vissers JP, Butter LM, Claessen N, Calcagni A, Kors L, Gethings LA, Bakker SJ, de Borst MH, Navis GJ, Liebisch G, Speijer D, van den Bergh Weerman MA, Jung B, Aten J, Steenbergen E, Schmitz G, Ballabio A, Florquin S, Aerts JM, Leemans JC.

J Pathol. 2018 Dec;246(4):470-484. doi: 10.1002/path.5150. Epub 2018 Nov 5.

PMID:
30073645
25.

Chemical Proteomic Analysis of Serine Hydrolase Activity in Niemann-Pick Type C Mouse Brain.

van Rooden EJ, van Esbroeck ACM, Baggelaar MP, Deng H, Florea BI, Marques ARA, Ottenhoff R, Boot RG, Overkleeft HS, Aerts JMFG, van der Stelt M.

Front Neurosci. 2018 Jul 3;12:440. doi: 10.3389/fnins.2018.00440. eCollection 2018.

26.

Locoregional control and survival after lymph node SBRT in oligometastatic disease.

Loi M, Frelinghuysen M, Klass ND, Oomen-De Hoop E, Granton PV, Aerts J, Verhoef C, Nuyttens J.

Clin Exp Metastasis. 2018 Oct;35(7):625-633. doi: 10.1007/s10585-018-9922-x. Epub 2018 Jul 11.

27.

Disentangling the role of TRPM4 in hippocampus-dependent plasticity and learning: an electrophysiological, behavioral and FMRI approach.

Bovet-Carmona M, Menigoz A, Pinto S, Tambuyzer T, Krautwald K, Voets T, Aerts JM, Angenstein F, Vennekens R, Balschun D.

Brain Struct Funct. 2018 Nov;223(8):3557-3576. doi: 10.1007/s00429-018-1706-1. Epub 2018 Jul 3.

PMID:
29971514
28.

Collagen Degradation and Formation Are Elevated in Exacerbated COPD Compared With Stable Disease.

Schumann DM, Leeming D, Papakonstantinou E, Blasi F, Kostikas K, Boersma W, Louis R, Milenkovic B, Aerts J, Sand JMB, Wouters EFM, Rohde G, Prat C, Torres A, Welte T, Tamm M, Karsdal M, Stolz D.

Chest. 2018 Oct;154(4):798-807. doi: 10.1016/j.chest.2018.06.028. Epub 2018 Jun 30.

PMID:
29966667
29.

High-throughput image-based monitoring of cell aggregation and microspheroid formation.

Deckers T, Lambrechts T, Viazzi S, Nilsson Hall G, Papantoniou I, Bloemen V, Aerts JM.

PLoS One. 2018 Jun 28;13(6):e0199092. doi: 10.1371/journal.pone.0199092. eCollection 2018.

30.

Immune checkpoint blockade therapy of mesothelioma: a clinical and radiological challenge.

Calabrò L, Morra A, Cornelissen R, Aerts J, Maio M.

Cancer Immunol Immunother. 2018 Aug;67(8):1317-1324. doi: 10.1007/s00262-018-2191-3. Epub 2018 Jun 26. Review.

PMID:
29943157
31.

Potential of memory T cells in bridging preoperative chemoradiation and immunotherapy in rectal cancer.

de Mey S, Jiang H, Wang H, Engels B, Gevaert T, Dufait I, Feron O, Aerts J, Verovski V, De Ridder M.

Radiother Oncol. 2018 Jun;127(3):361-369. doi: 10.1016/j.radonc.2018.04.003. Epub 2018 Jun 2. Review.

PMID:
29871814
32.

Potential Molecular Signatures Predictive of Lung Cancer Brain Metastasis.

Pedrosa RMSM, Mustafa DAM, Aerts JGJV, Kros JM.

Front Oncol. 2018 May 11;8:159. doi: 10.3389/fonc.2018.00159. eCollection 2018. Review.

33.

Modulation of Innate Immune-Related Genes and Glucocorticoid Synthesis in Gnotobiotic Full-Sibling European Sea Bass (Dicentrarchus labrax) Larvae Challenged With Vibrio anguillarum.

Reyes-López FE, Aerts J, Vallejos-Vidal E, Ampe B, Dierckens K, Tort L, Bossier P.

Front Immunol. 2018 May 8;9:914. doi: 10.3389/fimmu.2018.00914. eCollection 2018.

34.

Biomarkers in malignant mesothelioma-an unfulfilled need or a waste of resources?

Cornelissen R, Aerts JGJV.

J Thorac Dis. 2018 Apr;10(Suppl 9):S1084-S1087. doi: 10.21037/jtd.2018.03.128. No abstract available.

35.

Spiro-epoxyglycosides as Activity-Based Probes for Glycoside Hydrolase Family 99 Endomannosidase/Endomannanase.

Schröder SP, Kallemeijn WW, Debets MF, Hansen T, Sobala LF, Hakki Z, Williams SJ, Beenakker TJM, Aerts JMFG, van der Marel GA, Codée JDC, Davies GJ, Overkleeft HS.

Chemistry. 2018 Jul 11;24(39):9983-9992. doi: 10.1002/chem.201801902. Epub 2018 Jun 21.

36.

Publisher Correction: Using high-amplitude and focused transcranial alternating current stimulation to entrain physiological tremor.

Khatoun A, Breukers J, Op de Beeck S, Nica IG, Aerts JM, Seynaeve L, Haeck T, Asamoah B, Mc Laughlin M.

Sci Rep. 2018 May 23;8(1):8221. doi: 10.1038/s41598-018-26013-3.

37.
38.

Treatment Satisfaction of Patients With Advanced Non-Small-cell Lung Cancer Receiving Platinum-based Chemotherapy: Results From a Prospective Cohort Study (PERSONAL).

Visser S, de Mol M, Cheung K, van Toor JJ, van Walree NC, Stricker BH, Den Oudsten BL, Aerts JGJV.

Clin Lung Cancer. 2018 Jul;19(4):e503-e516. doi: 10.1016/j.cllc.2018.03.003. Epub 2018 Mar 17.

PMID:
29705017
39.

Association between single-nucleotide polymorphisms and adverse events in nivolumab-treated non-small cell lung cancer patients.

Bins S, Basak EA, El Bouazzaoui S, Koolen SLW, Oomen-de Hoop E, van der Leest CH, van der Veldt AAM, Sleijfer S, Debets R, van Schaik RHN, Aerts JGJV, Mathijssen RHJ.

Br J Cancer. 2018 May;118(10):1296-1301. doi: 10.1038/s41416-018-0074-1. Epub 2018 Apr 26.

PMID:
29695768
40.

Nicotiana benthamiana α-galactosidase A1.1 can functionally complement human α-galactosidase A deficiency associated with Fabry disease.

Kytidou K, Beekwilder J, Artola M, van Meel E, Wilbers RHP, Moolenaar GF, Goosen N, Ferraz MJ, Katzy R, Voskamp P, Florea BI, Hokke CH, Overkleeft HS, Schots A, Bosch D, Pannu N, Aerts JMFG.

J Biol Chem. 2018 Jun 29;293(26):10042-10058. doi: 10.1074/jbc.RA118.001774. Epub 2018 Apr 19.

PMID:
29674318
41.

Do wild-caught urban house sparrows show desensitized stress responses to a novel stressor?

Salleh Hudin N, Teyssier A, Aerts J, Fairhurst GD, Strubbe D, White J, De Neve L, Lens L.

Biol Open. 2018 Jun 15;7(6). pii: bio031849. doi: 10.1242/bio.031849. Erratum in: Biol Open. 2018 Sep 28;7(9):.

42.

Escalating impacts of climate extremes on critical infrastructures in Europe.

Forzieri G, Bianchi A, Silva FBE, Marin Herrera MA, Leblois A, Lavalle C, Aerts JCJH, Feyen L.

Glob Environ Change. 2018 Jan;48:97-107. doi: 10.1016/j.gloenvcha.2017.11.007.

43.

Heterogeneity in Immune Cell Content in Malignant Pleural Mesothelioma.

Minnema-Luiting J, Vroman H, Aerts J, Cornelissen R.

Int J Mol Sci. 2018 Mar 30;19(4). pii: E1041. doi: 10.3390/ijms19041041. Review.

44.

Gluco-1 H-imidazole: A New Class of Azole-Type β-Glucosidase Inhibitor.

Schröder SP, Wu L, Artola M, Hansen T, Offen WA, Ferraz MJ, Li KY, Aerts JMFG, van der Marel GA, Codée JDC, Davies GJ, Overkleeft HS.

J Am Chem Soc. 2018 Apr 18;140(15):5045-5048. doi: 10.1021/jacs.8b02399. Epub 2018 Apr 4.

45.

Using high-amplitude and focused transcranial alternating current stimulation to entrain physiological tremor.

Khatoun A, Breukers J, Op de Beeck S, Nica IG, Aerts JM, Seynaeve L, Haeck T, Asamoah B, Mc Laughlin M.

Sci Rep. 2018 Mar 21;8(1):4927. doi: 10.1038/s41598-018-23290-w. Erratum in: Sci Rep. 2018 May 23;8(1):8221.

46.

IFNΛ3/4 locus polymorphisms and IFNΛ3 circulating levels are associated with COPD severity and outcomes.

Egli A, Mandal J, Schumann DM, Roth M, Thomas B, Lorne Tyrrell D, Blasi F, Kostikas K, Boersma W, Milenkovic B, Lacoma A, Rentsch K, Rohde GGU, Louis R, Aerts JG, Welte T, Torres A, Tamm M, Stolz D.

BMC Pulm Med. 2018 Mar 21;18(1):51. doi: 10.1186/s12890-018-0616-6.

47.

Erratum: Conceptualization and validation of an open-source closed-loop deep brain stimulation system in rat.

Wu H, Ghekiere H, Beeckmans D, Tambuyzer T, van Kuyck K, Aerts JM, Nuttin B.

Sci Rep. 2018 Mar 19;8:46954. doi: 10.1038/srep46954.

48.

Factors affecting local control of pulmonary oligometastases treated with stereotactic body radiotherapy.

Sharma A, Duijm M, Oomen-de Hoop E, Aerts JG, Verhoef C, Hoogeman M, Nuyttens JJ.

Acta Oncol. 2018 Aug;57(8):1031-1037. doi: 10.1080/0284186X.2018.1445285. Epub 2018 Feb 28.

PMID:
29488414
49.

Immune checkpoint blockade combined with IL-6 and TGF-β inhibition improves the therapeutic outcome of mRNA-based immunotherapy.

Bialkowski L, Van der Jeught K, Bevers S, Tjok Joe P, Renmans D, Heirman C, Aerts JL, Thielemans K.

Int J Cancer. 2018 Aug 1;143(3):686-698. doi: 10.1002/ijc.31331. Epub 2018 Mar 13.

PMID:
29464699
50.

HEPES activates a MiT/TFE-dependent lysosomal-autophagic gene network in cultured cells: A call for caution.

Tol MJ, van der Lienden MJC, Gabriel TL, Hagen JJ, Scheij S, Veenendaal T, Klumperman J, Donker-Koopman WE, Verhoeven AJ, Overkleeft H, Aerts JM, Argmann CA, van Eijk M.

Autophagy. 2018;14(3):437-449. doi: 10.1080/15548627.2017.1419118. Epub 2018 Feb 17.

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