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Items: 1 to 50 of 128

1.

Influence of local epidemiology on the performance of common colistin drug susceptibility testing methods.

Asar L, Pfefferle S, Lütgehetmann M, Hoffmann A, Katchanov J, Aepfelbacher M, Rohde H, Maurer FP.

PLoS One. 2019 Jun 6;14(6):e0217468. doi: 10.1371/journal.pone.0217468. eCollection 2019.

2.

Activation of the macroautophagy pathway by Yersinia enterocolitica promotes intracellular multiplication and egress of yersiniae from epithelial cells.

Valencia Lopez MJ, Schimmeck H, Gropengießer J, Middendorf L, Quitmann M, Schneider C, Holstermann B, Wacker R, Heussler V, Reimer R, Aepfelbacher M, Ruckdeschel K.

Cell Microbiol. 2019 May 17:e13046. doi: 10.1111/cmi.13046. [Epub ahead of print]

PMID:
31099152
3.

Extended-spectrum β-lactamase-producing Enterobacteriaceae among geckos (Hemidactylus brookii) in a Ghanaian hospital.

Eibach D, Nagel M, Lorenzen S, Hogan B, Belmar Campos C, Aepfelbacher M, Sarpong N, May J.

Clin Microbiol Infect. 2019 Apr 12. pii: S1198-743X(19)30159-4. doi: 10.1016/j.cmi.2019.04.007. [Epub ahead of print] No abstract available.

PMID:
30986561
4.

Visualization of translocons in Yersinia type III protein secretion machines during host cell infection.

Nauth T, Huschka F, Schweizer M, Bosse JB, Diepold A, Failla AV, Steffen A, Stradal TEB, Wolters M, Aepfelbacher M.

PLoS Pathog. 2018 Dec 26;14(12):e1007527. doi: 10.1371/journal.ppat.1007527. eCollection 2018 Dec.

5.

Megahertz serial crystallography.

Wiedorn MO, Oberthür D, Bean R, Schubert R, Werner N, Abbey B, Aepfelbacher M, Adriano L, Allahgholi A, Al-Qudami N, Andreasson J, Aplin S, Awel S, Ayyer K, Bajt S, Barák I, Bari S, Bielecki J, Botha S, Boukhelef D, Brehm W, Brockhauser S, Cheviakov I, Coleman MA, Cruz-Mazo F, Danilevski C, Darmanin C, Doak RB, Domaracky M, Dörner K, Du Y, Fangohr H, Fleckenstein H, Frank M, Fromme P, Gañán-Calvo AM, Gevorkov Y, Giewekemeyer K, Ginn HM, Graafsma H, Graceffa R, Greiffenberg D, Gumprecht L, Göttlicher P, Hajdu J, Hauf S, Heymann M, Holmes S, Horke DA, Hunter MS, Imlau S, Kaukher A, Kim Y, Klyuev A, Knoška J, Kobe B, Kuhn M, Kupitz C, Küpper J, Lahey-Rudolph JM, Laurus T, Le Cong K, Letrun R, Xavier PL, Maia L, Maia FRNC, Mariani V, Messerschmidt M, Metz M, Mezza D, Michelat T, Mills G, Monteiro DCF, Morgan A, Mühlig K, Munke A, Münnich A, Nette J, Nugent KA, Nuguid T, Orville AM, Pandey S, Pena G, Villanueva-Perez P, Poehlsen J, Previtali G, Redecke L, Riekehr WM, Rohde H, Round A, Safenreiter T, Sarrou I, Sato T, Schmidt M, Schmitt B, Schönherr R, Schulz J, Sellberg JA, Seibert MM, Seuring C, Shelby ML, Shoeman RL, Sikorski M, Silenzi A, Stan CA, Shi X, Stern S, Sztuk-Dambietz J, Szuba J, Tolstikova A, Trebbin M, Trunk U, Vagovic P, Ve T, Weinhausen B, White TA, Wrona K, Xu C, Yefanov O, Zatsepin N, Zhang J, Perbandt M, Mancuso AP, Betzel C, Chapman H, Barty A.

Nat Commun. 2018 Oct 2;9(1):4025. doi: 10.1038/s41467-018-06156-7.

6.

Nrf2 Sequesters Keap1 Preventing Podosome Disassembly: A Quintessential Duet Moonlights in Endothelium.

Kloska D, Kopacz A, Cysewski D, Aepfelbacher M, Dulak J, Jozkowicz A, Grochot-Przeczek A.

Antioxid Redox Signal. 2019 May 10;30(14):1709-1730. doi: 10.1089/ars.2018.7505. Epub 2018 Oct 25.

PMID:
30198307
7.

Extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae in local and imported poultry meat in Ghana.

Eibach D, Dekker D, Gyau Boahen K, Wiafe Akenten C, Sarpong N, Belmar Campos C, Berneking L, Aepfelbacher M, Krumkamp R, Owusu-Dabo E, May J.

Vet Microbiol. 2018 Apr;217:7-12. doi: 10.1016/j.vetmic.2018.02.023. Epub 2018 Mar 22.

PMID:
29615260
8.

Two-tier approach combining molecular and culture-based techniques for optimized detection of vancomycin-resistant enterococci.

Both A, Franke GC, Mirwald N, Lütgehetmann M, Christner M, Klupp EM, Belmar Campos C, Büttner H, Aepfelbacher M, Rohde H.

Diagn Microbiol Infect Dis. 2017 Dec;89(4):253-257. doi: 10.1016/j.diagmicrobio.2017.08.009. Epub 2017 Aug 24.

PMID:
28974396
9.

p38MAPK/MK2-dependent phosphorylation controls cytotoxic RIPK1 signalling in inflammation and infection.

Menon MB, Gropengießer J, Fischer J, Novikova L, Deuretzbacher A, Lafera J, Schimmeck H, Czymmeck N, Ronkina N, Kotlyarov A, Aepfelbacher M, Gaestel M, Ruckdeschel K.

Nat Cell Biol. 2017 Oct;19(10):1248-1259. doi: 10.1038/ncb3614. Epub 2017 Sep 18.

PMID:
28920954
10.

Emergence of ceftazidime/avibactam non-susceptibility in an MDR Klebsiella pneumoniae isolate.

Both A, Büttner H, Huang J, Perbandt M, Belmar Campos C, Christner M, Maurer FP, Kluge S, König C, Aepfelbacher M, Wichmann D, Rohde H.

J Antimicrob Chemother. 2017 Sep 1;72(9):2483-2488. doi: 10.1093/jac/dkx179.

PMID:
28637339
11.

Molecular analysis of the ramRA locus in clinical Klebsiella pneumoniae isolates with reduced susceptibility to tigecycline.

Campos CB, Aepfelbacher M, Hentschke M.

New Microbiol. 2017 Apr;40(2):135-138. Epub 2017 Apr 3.

12.

First report of Escherichia coli co-producing NDM-1 and OXA-232.

Both A, Huang J, Kaase M, Hezel J, Wertheimer D, Fenner I, Günther T, Grundhoff A, Büttner H, Aepfelbacher M, Rohde H, Hentschke M.

Diagn Microbiol Infect Dis. 2016 Dec;86(4):437-438. doi: 10.1016/j.diagmicrobio.2016.09.005. Epub 2016 Sep 16.

PMID:
27681362
13.

Acting on Actin: Rac and Rho Played by Yersinia.

Aepfelbacher M, Wolters M.

Curr Top Microbiol Immunol. 2017;399:201-220. doi: 10.1007/82_2016_33. Review.

PMID:
27744508
14.

Tedizolid susceptibility in linezolid- and vancomycin-resistant Enterococcus faecium isolates.

Klupp EM, Both A, Belmar Campos C, Büttner H, König C, Christopeit M, Christner M, Aepfelbacher M, Rohde H.

Eur J Clin Microbiol Infect Dis. 2016 Dec;35(12):1957-1961. Epub 2016 Aug 15.

PMID:
27525679
15.

Staphylococcus aureus recruits Cdc42GAP through recycling endosomes and the exocyst to invade human endothelial cells.

Rauch L, Hennings K, Trasak C, Röder A, Schröder B, Koch-Nolte F, Rivera-Molina F, Toomre D, Aepfelbacher M.

J Cell Sci. 2016 Aug 1;129(15):2937-49. doi: 10.1242/jcs.186213. Epub 2016 Jun 16.

16.

Immunosuppressive Yersinia Effector YopM Binds DEAD Box Helicase DDX3 to Control Ribosomal S6 Kinase in the Nucleus of Host Cells.

Berneking L, Schnapp M, Rumm A, Trasak C, Ruckdeschel K, Alawi M, Grundhoff A, Kikhney AG, Koch-Nolte F, Buck F, Perbandt M, Betzel C, Svergun DI, Hentschke M, Aepfelbacher M.

PLoS Pathog. 2016 Jun 14;12(6):e1005660. doi: 10.1371/journal.ppat.1005660. eCollection 2016 Jun.

17.

Extended spectrum beta-lactamase producing Enterobacteriaceae causing bloodstream infections in rural Ghana, 2007-2012.

Eibach D, Belmar Campos C, Krumkamp R, Al-Emran HM, Dekker D, Boahen KG, Kreuels B, Adu-Sarkodie Y, Aepfelbacher M, Park SE, Panzner U, Marks F, May J.

Int J Med Microbiol. 2016 Jun;306(4):249-54. doi: 10.1016/j.ijmm.2016.05.006. Epub 2016 May 10.

PMID:
27222489
18.

Ex vivo perfusion of the isolated rat small intestine as a novel model of Salmonella enteritis.

Boyle EC, Dombrowsky H, Sarau J, Braun J, Aepfelbacher M, Lautenschläger I, Grassl GA.

Am J Physiol Gastrointest Liver Physiol. 2016 Jan 15;310(2):G55-63. doi: 10.1152/ajpgi.00444.2014. Epub 2015 Nov 12.

19.

Hepatitis E Virus.

Pauli G, Aepfelbacher M, Bauerfeind U, Blümel J, Burger R, Gärtner B, Gröner A, Gürtler L, Heiden M, Hildebrandt M, Jansen B, Offergeld R, Schlenkrich U, Schottstedt V, Seitz R, Strobel J, Willkommen H, Baylis SA; German Advisory Committee Blood (Arbeitskreis Blut), Subgroup ‘Assessment of Pathogens Transmissible by Blood’.

Transfus Med Hemother. 2015 Jul;42(4):247-65. doi: 10.1159/000431191. Epub 2015 Jun 1. No abstract available.

20.

Analysis of Yersinia enterocolitica Effector Translocation into Host Cells Using Beta-lactamase Effector Fusions.

Wolters M, Zobiak B, Nauth T, Aepfelbacher M.

J Vis Exp. 2015 Oct 13;(104). doi: 10.3791/53115.

21.

Tropheryma whipplei in children with diarrhoea in rural Ghana.

Vinnemeier CD, Klupp EM, Krumkamp R, Rolling T, Fischer N, Owusu-Dabo E, Addo MM, Adu-Sarkodie Y, Käsmaier J, Aepfelbacher M, Cramer JP, May J, Tannich E.

Clin Microbiol Infect. 2016 Jan;22(1):65.e1-65.e3. doi: 10.1016/j.cmi.2015.09.022. Epub 2015 Oct 8.

22.

Evaluation of Unbiased Next-Generation Sequencing of RNA (RNA-seq) as a Diagnostic Method in Influenza Virus-Positive Respiratory Samples.

Fischer N, Indenbirken D, Meyer T, Lütgehetmann M, Lellek H, Spohn M, Aepfelbacher M, Alawi M, Grundhoff A.

J Clin Microbiol. 2015 Jul;53(7):2238-50. doi: 10.1128/JCM.02495-14. Epub 2015 May 13.

23.

A role for exocyst in maturation and bactericidal function of staphylococci-containing endothelial cell phagosomes.

Rauch L, Hennings K, Aepfelbacher M.

Traffic. 2014 Oct;15(10):1083-98. doi: 10.1111/tra.12189. Epub 2014 Aug 11.

24.

Rapid MALDI-TOF mass spectrometry strain typing during a large outbreak of Shiga-Toxigenic Escherichia coli.

Christner M, Trusch M, Rohde H, Kwiatkowski M, Schlüter H, Wolters M, Aepfelbacher M, Hentschke M.

PLoS One. 2014 Jul 8;9(7):e101924. doi: 10.1371/journal.pone.0101924. eCollection 2014.

25.

[Surveillance reports on pathogens and their antibiotic resistance patterns - a recommendation for standardization].

Warnke P, Aepfelbacher M, Fickenscher H, Solbach W, Steinmetz I, Podbielski A.

Dtsch Med Wochenschr. 2014 Jun;139(25-26):1377-82. doi: 10.1055/s-0034-1370124. Epub 2014 Jun 10. Review. German.

PMID:
24914516
26.

Rapid metagenomic diagnostics for suspected outbreak of severe pneumonia.

Fischer N, Rohde H, Indenbirken D, Günther T, Reumann K, Lütgehetmann M, Meyer T, Kluge S, Aepfelbacher M, Alawi M, Grundhoff A.

Emerg Infect Dis. 2014 Jun;20(6):1072-5. doi: 10.3201/eid2006.131526. No abstract available.

27.

Prevalence and genotypes of extended spectrum beta-lactamases in Enterobacteriaceae isolated from human stool and chicken meat in Hamburg, Germany.

Belmar Campos C, Fenner I, Wiese N, Lensing C, Christner M, Rohde H, Aepfelbacher M, Fenner T, Hentschke M.

Int J Med Microbiol. 2014 Jul;304(5-6):678-84. doi: 10.1016/j.ijmm.2014.04.012. Epub 2014 May 6.

PMID:
24856867
28.

Improved detection of bacterial central nervous system infections by use of a broad-range PCR assay.

Meyer T, Franke G, Polywka SK, Lütgehetmann M, Gbadamosi J, Magnus T, Aepfelbacher M.

J Clin Microbiol. 2014 May;52(5):1751-3. doi: 10.1128/JCM.00469-14. Epub 2014 Mar 12.

29.

Cell death triggered by Yersinia enterocolitica identifies processing of the proinflammatory signal adapter MyD88 as a general event in the execution of apoptosis.

Novikova L, Czymmeck N, Deuretzbacher A, Buck F, Richter K, Weber AN, Aepfelbacher M, Ruckdeschel K.

J Immunol. 2014 Feb 1;192(3):1209-19. doi: 10.4049/jimmunol.1203464. Epub 2013 Dec 20.

30.

Cytotoxic necrotizing factor-Y boosts Yersinia effector translocation by activating Rac protein.

Wolters M, Boyle EC, Lardong K, Trülzsch K, Steffen A, Rottner K, Ruckdeschel K, Aepfelbacher M.

J Biol Chem. 2013 Aug 9;288(32):23543-53. doi: 10.1074/jbc.M112.448662. Epub 2013 Jun 26.

31.

A culture-independent sequence-based metagenomics approach to the investigation of an outbreak of Shiga-toxigenic Escherichia coli O104:H4.

Loman NJ, Constantinidou C, Christner M, Rohde H, Chan JZ, Quick J, Weir JC, Quince C, Smith GP, Betley JR, Aepfelbacher M, Pallen MJ.

JAMA. 2013 Apr 10;309(14):1502-10. doi: 10.1001/jama.2013.3231.

PMID:
23571589
32.

Duration of fecal shedding of Shiga toxin-producing Escherichia coli O104:H4 in patients infected during the 2011 outbreak in Germany: a multicenter study.

Vonberg RP, Höhle M, Aepfelbacher M, Bange FC, Belmar Campos C, Claussen K, Christner M, Cramer JP, Haller H, Hornef M, Fickenscher H, Fraedrich K, Knobloch JK, Kühbacher T, Manns MP, Nitschke M, Peters G, Pulz M, Rohde H, Roseland RT, Sayk F, Schaumburg F, Schöcklmann HO, Schubert S, Solbach W, Karch H, Suerbaum S.

Clin Infect Dis. 2013 Apr;56(8):1132-40. doi: 10.1093/cid/cis1218. Epub 2013 Jan 8.

PMID:
23300241
33.

Emergence of carbapenemases in Gram-negative bacteria in Hamburg, Germany.

Hentschke M, Goritzka V, Campos CB, Merkel P, Ilchmann C, Lellek H, Scherpe S, Aepfelbacher M, Rohde H.

Diagn Microbiol Infect Dis. 2011 Nov;71(3):312-5. doi: 10.1016/j.diagmicrobio.2011.07.011. Epub 2011 Sep 6.

PMID:
21899979
34.

Organelle segregation into Plasmodium liver stage merozoites.

Stanway RR, Mueller N, Zobiak B, Graewe S, Froehlke U, Zessin PJ, Aepfelbacher M, Heussler VT.

Cell Microbiol. 2011 Nov;13(11):1768-82. doi: 10.1111/j.1462-5822.2011.01657.x. Epub 2011 Aug 31.

PMID:
21801293
35.

Open-source genomic analysis of Shiga-toxin-producing E. coli O104:H4.

Rohde H, Qin J, Cui Y, Li D, Loman NJ, Hentschke M, Chen W, Pu F, Peng Y, Li J, Xi F, Li S, Li Y, Zhang Z, Yang X, Zhao M, Wang P, Guan Y, Cen Z, Zhao X, Christner M, Kobbe R, Loos S, Oh J, Yang L, Danchin A, Gao GF, Song Y, Li Y, Yang H, Wang J, Xu J, Pallen MJ, Wang J, Aepfelbacher M, Yang R; E. coli O104:H4 Genome Analysis Crowd-Sourcing Consortium.

N Engl J Med. 2011 Aug 25;365(8):718-24. doi: 10.1056/NEJMoa1107643. Epub 2011 Jul 27.

36.

Staphylococcus epidermidis uses distinct mechanisms of biofilm formation to interfere with phagocytosis and activation of mouse macrophage-like cells 774A.1.

Schommer NN, Christner M, Hentschke M, Ruckdeschel K, Aepfelbacher M, Rohde H.

Infect Immun. 2011 Jun;79(6):2267-76. doi: 10.1128/IAI.01142-10. Epub 2011 Mar 14.

37.

CMY-42, a novel plasmid-mediated CMY-2 variant AmpC beta-lactamase.

Hentschke M, Kotsakis SD, Wolters M, Heisig P, Miriagou V, Aepfelbacher M.

Microb Drug Resist. 2011 Jun;17(2):165-9. doi: 10.1089/mdr.2010.0137. Epub 2011 Mar 9.

PMID:
21388298
38.

Activity modulation of the bacterial Rho GAP YopE: an inspiration for the investigation of mammalian Rho GAPs.

Aepfelbacher M, Roppenser B, Hentschke M, Ruckdeschel K.

Eur J Cell Biol. 2011 Nov;90(11):951-4. doi: 10.1016/j.ejcb.2010.12.004. Epub 2011 Jan 20. Review.

PMID:
21255863
39.

Destabilization of YopE by the ubiquitin-proteasome pathway fine-tunes Yop delivery into host cells and facilitates systemic spread of Yersinia enterocolitica in host lymphoid tissue.

Gaus K, Hentschke M, Czymmeck N, Novikova L, Trülzsch K, Valentin-Weigand P, Aepfelbacher M, Ruckdeschel K.

Infect Immun. 2011 Mar;79(3):1166-75. doi: 10.1128/IAI.00694-10. Epub 2010 Dec 13.

40.

Yersinia virulence factor YopM induces sustained RSK activation by interfering with dephosphorylation.

Hentschke M, Berneking L, Belmar Campos C, Buck F, Ruckdeschel K, Aepfelbacher M.

PLoS One. 2010 Oct 5;5(10). pii: e13165. doi: 10.1371/journal.pone.0013165.

41.

MALDI-TOF MS fingerprinting allows for discrimination of major methicillin-resistant Staphylococcus aureus lineages.

Wolters M, Rohde H, Maier T, Belmar-Campos C, Franke G, Scherpe S, Aepfelbacher M, Christner M.

Int J Med Microbiol. 2011 Jan;301(1):64-8. doi: 10.1016/j.ijmm.2010.06.002. Epub 2010 Aug 21.

PMID:
20728405
42.

Diagnosis of Toxoplasma gondii infection after allogeneic stem cell transplant can be difficult and requires intensive scrutiny.

Cavattoni I, Ayuk F, Zander AR, Zabelina T, Bacher A, Cayroglu E, Knospe V, Illies T, Aepfelbacher M, Richard G, Kröger N, Bacher U.

Leuk Lymphoma. 2010 Aug;51(8):1530-5. doi: 10.3109/10428194.2010.494260.

PMID:
20578813
43.

Xenotropic murine leukemia virus-related gammaretrovirus in respiratory tract.

Fischer N, Schulz C, Stieler K, Hohn O, Lange C, Drosten C, Aepfelbacher M.

Emerg Infect Dis. 2010 Jun;16(6):1000-2. doi: 10.3201/eid1606.100066.

44.

ramR mutations in clinical isolates of Klebsiella pneumoniae with reduced susceptibility to tigecycline.

Hentschke M, Wolters M, Sobottka I, Rohde H, Aepfelbacher M.

Antimicrob Agents Chemother. 2010 Jun;54(6):2720-3. doi: 10.1128/AAC.00085-10. Epub 2010 Mar 29.

45.

Rapid identification of bacteria from positive blood culture bottles by use of matrix-assisted laser desorption-ionization time of flight mass spectrometry fingerprinting.

Christner M, Rohde H, Wolters M, Sobottka I, Wegscheider K, Aepfelbacher M.

J Clin Microbiol. 2010 May;48(5):1584-91. doi: 10.1128/JCM.01831-09. Epub 2010 Mar 17.

46.

Host range and cellular tropism of the human exogenous gammaretrovirus XMRV.

Stieler K, Schulz C, Lavanya M, Aepfelbacher M, Stocking C, Fischer N.

Virology. 2010 Mar 30;399(1):23-30. doi: 10.1016/j.virol.2009.12.028. Epub 2010 Jan 27.

47.

Combined ramR mutation and presence of a Tn1721-associated tet(A) variant in a clinical isolate of Salmonella enterica serovar Hadar resistant to tigecycline.

Hentschke M, Christner M, Sobottka I, Aepfelbacher M, Rohde H.

Antimicrob Agents Chemother. 2010 Mar;54(3):1319-22. doi: 10.1128/AAC.00993-09. Epub 2009 Dec 22.

48.

The giant extracellular matrix-binding protein of Staphylococcus epidermidis mediates biofilm accumulation and attachment to fibronectin.

Christner M, Franke GC, Schommer NN, Wendt U, Wegert K, Pehle P, Kroll G, Schulze C, Buck F, Mack D, Aepfelbacher M, Rohde H.

Mol Microbiol. 2010 Jan;75(1):187-207. doi: 10.1111/j.1365-2958.2009.06981.x. Epub 2009 Nov 25.

49.

Epidemiology, variable genetic organization and regulation of the EDIN-B toxin in Staphylococcus aureus from bacteraemic patients.

Franke GC, Böckenholt A, Sugai M, Rohde H, Aepfelbacher M.

Microbiology. 2010 Mar;156(Pt 3):860-72. doi: 10.1099/mic.0.030304-0. Epub 2009 Oct 29.

PMID:
19875439
50.

Beta1 integrin-dependent engulfment of Yersinia enterocolitica by macrophages is coupled to the activation of autophagy and suppressed by type III protein secretion.

Deuretzbacher A, Czymmeck N, Reimer R, Trülzsch K, Gaus K, Hohenberg H, Heesemann J, Aepfelbacher M, Ruckdeschel K.

J Immunol. 2009 Nov 1;183(9):5847-60. doi: 10.4049/jimmunol.0804242. Epub 2009 Oct 7.

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