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Items: 1 to 50 of 310

1.

Assembly Kinetics of Vimentin Tetramers to Unit-Length Filaments: A Stopped-Flow Study.

Mücke N, Kämmerer L, Winheim S, Kirmse R, Krieger J, Mildenberger M, Baßler J, Hurt E, Goldmann WH, Aebi U, Toth K, Langowski J, Herrmann H.

Biophys J. 2018 May 22;114(10):2408-2418. doi: 10.1016/j.bpj.2018.04.032. Epub 2018 May 10.

2.

Swiss National Research Programme "Opportunities and Risks of Nanomaterials" (NRP 64): key findings.

Aebi U, Gehr P.

J Nanobiotechnology. 2017 Jun 24;15(1):47. doi: 10.1186/s12951-017-0282-5. No abstract available.

3.

Intermediate Filaments: Structure and Assembly.

Herrmann H, Aebi U.

Cold Spring Harb Perspect Biol. 2016 Nov 1;8(11). pii: a018242. doi: 10.1101/cshperspect.a018242. Review.

4.

Contributions of the lower dimer to supramolecular actin patterning revealed by TIRF microscopy.

Silván U, Hyotyla J, Mannherz HG, Ringler P, Müller SA, Aebi U, Maier T, Schoenenberger CA.

J Struct Biol. 2016 Aug;195(2):159-166. doi: 10.1016/j.jsb.2016.05.008. Epub 2016 May 14.

PMID:
27189866
5.

Distinct actin oligomers modulate differently the activity of actin nucleators.

Qu Z, Silvan U, Jockusch BM, Aebi U, Schoenenberger CA, Mannherz HG.

FEBS J. 2015 Oct;282(19):3824-40. doi: 10.1111/febs.13381. Epub 2015 Aug 11.

6.

Intermediate filament mechanics in vitro and in the cell: from coiled coils to filaments, fibers and networks.

Köster S, Weitz DA, Goldman RD, Aebi U, Herrmann H.

Curr Opin Cell Biol. 2015 Feb;32:82-91. doi: 10.1016/j.ceb.2015.01.001. Epub 2015 Jan 23. Review.

7.

Intermediate filaments: a dynamic network that controls cell mechanics.

Gruenbaum Y, Aebi U.

F1000Prime Rep. 2014 Jul 8;6:54. doi: 10.12703/P6-54. eCollection 2014. Review.

8.

The biodistribution of self-assembling protein nanoparticles shows they are promising vaccine platforms.

Yang Y, Neef T, Mittelholzer C, Garcia Garayoa E, Bläuenstein P, Schibli R, Aebi U, Burkhard P.

J Nanobiotechnology. 2013 Nov 12;11:36. doi: 10.1186/1477-3155-11-36.

9.

A tumorigenic actin mutant alters fibroblast morphology and multicellular assembly properties.

Blache U, Silván U, Plodinec M, Suetterlin R, Jakob R, Klebba I, Bentires-Alj M, Aebi U, Schoenenberger CA.

Cytoskeleton (Hoboken). 2013 Oct;70(10):635-50. doi: 10.1002/cm.21120. Epub 2013 Jul 19.

PMID:
23804571
10.

The nanomechanical signature of breast cancer.

Plodinec M, Loparic M, Monnier CA, Obermann EC, Zanetti-Dallenbach R, Oertle P, Hyotyla JT, Aebi U, Bentires-Alj M, Lim RY, Schoenenberger CA.

Nat Nanotechnol. 2012 Nov;7(11):757-65. doi: 10.1038/nnano.2012.167. Epub 2012 Oct 21.

PMID:
23085644
11.

Atomic structure of the vimentin central α-helical domain and its implications for intermediate filament assembly.

Chernyatina AA, Nicolet S, Aebi U, Herrmann H, Strelkov SV.

Proc Natl Acad Sci U S A. 2012 Aug 21;109(34):13620-5. doi: 10.1073/pnas.1206836109. Epub 2012 Aug 6.

12.

Sliding motion modulates stiffness and friction coefficient at the surface of tissue engineered cartilage.

Grad S, Loparic M, Peter R, Stolz M, Aebi U, Alini M.

Osteoarthritis Cartilage. 2012 Apr;20(4):288-95. doi: 10.1016/j.joca.2011.12.010. Epub 2012 Jan 10.

13.

Complex formation and kinetics of filament assembly exhibited by the simple epithelial keratins K8 and K18.

Lichtenstern T, Mücke N, Aebi U, Mauermann M, Herrmann H.

J Struct Biol. 2012 Jan;177(1):54-62. doi: 10.1016/j.jsb.2011.11.003. Epub 2011 Nov 9.

PMID:
22085677
14.

Lamin A and lamin C form homodimers and coexist in higher complex forms both in the nucleoplasmic fraction and in the lamina of cultured human cells.

Kolb T, Maass K, Hergt M, Aebi U, Herrmann H.

Nucleus. 2011 Sep-Oct;2(5):425-33. doi: 10.4161/nucl.2.5.17765.

PMID:
22033280
15.

An antiparallel actin dimer is associated with the endocytic pathway in mammalian cells.

Silván U, Boiteux C, Sütterlin R, Schroeder U, Mannherz HG, Jockusch BM, Bernèche S, Aebi U, Schoenenberger CA.

J Struct Biol. 2012 Jan;177(1):70-80. doi: 10.1016/j.jsb.2011.09.010. Epub 2011 Sep 25.

PMID:
21970948
16.

The nanomechanical properties of rat fibroblasts are modulated by interfering with the vimentin intermediate filament system.

Plodinec M, Loparic M, Suetterlin R, Herrmann H, Aebi U, Schoenenberger CA.

J Struct Biol. 2011 Jun;174(3):476-84. doi: 10.1016/j.jsb.2011.03.011. Epub 2011 Mar 21.

PMID:
21426942
17.

Simultaneous formation of right- and left-handed anti-parallel coiled-coil interfaces by a coil2 fragment of human lamin A.

Kapinos LE, Burkhard P, Herrmann H, Aebi U, Strelkov SV.

J Mol Biol. 2011 Apr 22;408(1):135-46. doi: 10.1016/j.jmb.2011.02.037. Epub 2011 Feb 24.

PMID:
21354179
18.

Vimentin organization modulates the formation of lamellipodia.

Helfand BT, Mendez MG, Murthy SN, Shumaker DK, Grin B, Mahammad S, Aebi U, Wedig T, Wu YI, Hahn KM, Inagaki M, Herrmann H, Goldman RD.

Mol Biol Cell. 2011 Apr 15;22(8):1274-89. doi: 10.1091/mbc.E10-08-0699. Epub 2011 Feb 23.

19.

An RGD-restricted substrate interface is sufficient for the adhesion, growth and cartilage forming capacity of human chondrocytes.

Vonwil D, Schuler M, Barbero A, Ströbel S, Wendt D, Textor M, Aebi U, Martin I.

Eur Cell Mater. 2010 Nov 11;20:316-28.

20.

Atomic force microscopy for biological imaging and mechanical testing across length scales.

Plodinec M, Loparic M, Aebi U.

Cold Spring Harb Protoc. 2010 Oct 1;2010(10):pdb.top86. doi: 10.1101/pdb.top86.

PMID:
20889710
21.

Preparation of microsphere tips for atomic force microscopy (AFM).

Plodinec M, Loparic M, Aebi U.

Cold Spring Harb Protoc. 2010 Oct 1;2010(10):pdb.prot5502. doi: 10.1101/pdb.prot5502.

PMID:
20889699
22.

Imaging collagen II using atomic force microscopy (AFM).

Plodinec M, Loparic M, Aebi U.

Cold Spring Harb Protoc. 2010 Oct 1;2010(10):pdb.prot5501. doi: 10.1101/pdb.prot5501.

PMID:
20889698
23.

Imaging fibroblast cells using atomic force microscopy (AFM).

Plodinec M, Loparic M, Aebi U.

Cold Spring Harb Protoc. 2010 Oct 1;2010(10):pdb.prot5500. doi: 10.1101/pdb.prot5500.

PMID:
20889697
24.

Imaging articular cartilage tissue using atomic force microscopy (AFM).

Plodinec M, Loparic M, Aebi U.

Cold Spring Harb Protoc. 2010 Oct 1;2010(10):pdb.prot5499. doi: 10.1101/pdb.prot5499.

PMID:
20889696
25.

Actin filament bundling and different nucleating effects of mouse Diaphanous-related formin FH2 domains on actin/ADF and actin/cofilin complexes.

Machaidze G, Sokoll A, Shimada A, Lustig A, Mazur A, Wittinghofer A, Aebi U, Mannherz HG.

J Mol Biol. 2010 Nov 5;403(4):529-45. doi: 10.1016/j.jmb.2010.09.017. Epub 2010 Oct 1.

PMID:
20869367
26.

Amyloid structure and assembly: insights from scanning transmission electron microscopy.

Goldsbury C, Baxa U, Simon MN, Steven AC, Engel A, Wall JS, Aebi U, Müller SA.

J Struct Biol. 2011 Jan;173(1):1-13. doi: 10.1016/j.jsb.2010.09.018. Epub 2010 Sep 22. Review.

27.

Fast quantitative single-molecule detection at ultralow concentrations.

Haas P, Then P, Wild A, Grange W, Zorman S, Hegner M, Calame M, Aebi U, Flammer J, Hecht B.

Anal Chem. 2010 Jul 15;82(14):6299-302. doi: 10.1021/ac100779c.

PMID:
20568715
28.

Micro- and nanomechanical analysis of articular cartilage by indentation-type atomic force microscopy: validation with a gel-microfiber composite.

Loparic M, Wirz D, Daniels AU, Raiteri R, Vanlandingham MR, Guex G, Martin I, Aebi U, Stolz M.

Biophys J. 2010 Jun 2;98(11):2731-40. doi: 10.1016/j.bpj.2010.02.013.

29.

Towards monitoring transport of single cargos across individual nuclear pore complexes by time-lapse atomic force microscopy.

Huang NP, Stubenrauch M, Köser J, Taschner N, Aebi U, Stolz M.

J Struct Biol. 2010 Aug;171(2):154-62. doi: 10.1016/j.jsb.2010.04.004. Epub 2010 Apr 13.

PMID:
20394822
30.

Atomic structure of vimentin coil 2.

Nicolet S, Herrmann H, Aebi U, Strelkov SV.

J Struct Biol. 2010 May;170(2):369-76. doi: 10.1016/j.jsb.2010.02.012. Epub 2010 Feb 20.

PMID:
20176112
31.

Characterization of the head-to-tail overlap complexes formed by human lamin A, B1 and B2 "half-minilamin" dimers.

Kapinos LE, Schumacher J, Mücke N, Machaidze G, Burkhard P, Aebi U, Strelkov SV, Herrmann H.

J Mol Biol. 2010 Feb 26;396(3):719-31. doi: 10.1016/j.jmb.2009.12.001. Epub 2009 Dec 7.

PMID:
20004208
32.

A nonadjuvanted polypeptide nanoparticle vaccine confers long-lasting protection against rodent malaria.

Kaba SA, Brando C, Guo Q, Mittelholzer C, Raman S, Tropel D, Aebi U, Burkhard P, Lanar DE.

J Immunol. 2009 Dec 1;183(11):7268-77. doi: 10.4049/jimmunol.0901957. Epub 2009 Nov 13.

33.

Structural analysis of a metazoan nuclear pore complex reveals a fused concentric ring architecture.

Frenkiel-Krispin D, Maco B, Aebi U, Medalia O.

J Mol Biol. 2010 Jan 22;395(3):578-86. doi: 10.1016/j.jmb.2009.11.010. Epub 2009 Nov 11.

PMID:
19913035
34.

Intermediate filaments: primary determinants of cell architecture and plasticity.

Herrmann H, Strelkov SV, Burkhard P, Aebi U.

J Clin Invest. 2009 Jul;119(7):1772-83. doi: 10.1172/JCI38214. Epub 2009 Jul 1. Review.

35.

Interference of amino-terminal desmin fragments with desmin filament formation.

Bär H, Sharma S, Kleiner H, Mücke N, Zentgraf H, Katus HA, Aebi U, Herrmann H.

Cell Motil Cytoskeleton. 2009 Nov;66(11):986-99. doi: 10.1002/cm.20396.

PMID:
19530175
36.

Vimentin coil 1A-A molecular switch involved in the initiation of filament elongation.

Meier M, Padilla GP, Herrmann H, Wedig T, Hergt M, Patel TR, Stetefeld J, Aebi U, Burkhard P.

J Mol Biol. 2009 Jul 10;390(2):245-61. doi: 10.1016/j.jmb.2009.04.067. Epub 2009 May 5.

PMID:
19422834
37.

Isolation, characterisation and molecular imaging of a high-molecular-weight insect biliprotein, a member of the hexameric arylphorin protein family.

Kayser H, Mann K, Machaidze G, Nimtz M, Ringler P, Müller SA, Aebi U.

J Mol Biol. 2009 May 29;389(1):74-89. doi: 10.1016/j.jmb.2009.03.075. Epub 2009 Apr 8.

PMID:
19361516
38.

Early detection of aging cartilage and osteoarthritis in mice and patient samples using atomic force microscopy.

Stolz M, Gottardi R, Raiteri R, Miot S, Martin I, Imer R, Staufer U, Raducanu A, Düggelin M, Baschong W, Daniels AU, Friederich NF, Aszodi A, Aebi U.

Nat Nanotechnol. 2009 Mar;4(3):186-92. doi: 10.1038/nnano.2008.410. Epub 2009 Feb 1. Erratum in: Nat Nanotechnol. 2010 Nov;5(11):821.

PMID:
19265849
39.

Near-UV circular dichroism reveals structural transitions of vimentin subunits during intermediate filament assembly.

Georgakopoulou S, Möller D, Sachs N, Herrmann H, Aebi U.

J Mol Biol. 2009 Feb 20;386(2):544-53. doi: 10.1016/j.jmb.2008.12.053. Epub 2008 Dec 30.

PMID:
19136013
40.

The measurement of biomechanical properties of porcine articular cartilage using atomic force microscopy.

Imer R, Akiyama T, F de Rooij N, Stolz M, Aebi U, F Friederich N, Staufer U.

Arch Histol Cytol. 2009;72(4-5):251-9.

41.

The supramolecular organization of the C. elegans nuclear lamin filament.

Ben-Harush K, Wiesel N, Frenkiel-Krispin D, Moeller D, Soreq E, Aebi U, Herrmann H, Gruenbaum Y, Medalia O.

J Mol Biol. 2009 Mar 13;386(5):1392-402. doi: 10.1016/j.jmb.2008.12.024. Epub 2008 Dec 16.

PMID:
19109977
42.

Peptide nanoparticles serve as a powerful platform for the immunogenic display of poorly antigenic actin determinants.

Schroeder U, Graff A, Buchmeier S, Rigler P, Silvan U, Tropel D, Jockusch BM, Aebi U, Burkhard P, Schoenenberger CA.

J Mol Biol. 2009 Mar 13;386(5):1368-81. doi: 10.1016/j.jmb.2008.11.023. Epub 2008 Nov 25.

PMID:
19063898
43.

Electron microscopy of intermediate filaments: teaming up with atomic force and confocal laser scanning microscopy.

Kreplak L, Richter K, Aebi U, Herrmann H.

Methods Cell Biol. 2008;88:273-97. doi: 10.1016/S0091-679X(08)00415-9. Review.

PMID:
18617039
44.

What transmission electron microscopes can visualize now and in the future.

Müller SA, Aebi U, Engel A.

J Struct Biol. 2008 Sep;163(3):235-45. doi: 10.1016/j.jsb.2008.05.008. Epub 2008 Jun 18. Review.

PMID:
18614377
45.

The highly conserved nuclear lamin Ig-fold binds to PCNA: its role in DNA replication.

Shumaker DK, Solimando L, Sengupta K, Shimi T, Adam SA, Grunwald A, Strelkov SV, Aebi U, Cardoso MC, Goldman RD.

J Cell Biol. 2008 Apr 21;181(2):269-80. doi: 10.1083/jcb.200708155.

46.

Towards an integrated understanding of the structure and mechanics of the cell nucleus.

Rowat AC, Lammerding J, Herrmann H, Aebi U.

Bioessays. 2008 Mar;30(3):226-36. doi: 10.1002/bies.20720. Review.

PMID:
18293361
47.

Towards reconciling structure and function in the nuclear pore complex.

Lim RY, Aebi U, Fahrenkrog B.

Histochem Cell Biol. 2008 Feb;129(2):105-16. doi: 10.1007/s00418-007-0371-x. Epub 2008 Jan 29. Review.

48.

Tensile properties of single desmin intermediate filaments.

Kreplak L, Herrmann H, Aebi U.

Biophys J. 2008 Apr 1;94(7):2790-9. doi: 10.1529/biophysj.107.119826. Epub 2008 Jan 4.

49.

Laminopathic mutations interfere with the assembly, localization, and dynamics of nuclear lamins.

Wiesel N, Mattout A, Melcer S, Melamed-Book N, Herrmann H, Medalia O, Aebi U, Gruenbaum Y.

Proc Natl Acad Sci U S A. 2008 Jan 8;105(1):180-5. Epub 2007 Dec 27.

50.

Atomic force microscopy of Mammalian urothelial surface.

Kreplak L, Wang H, Aebi U, Kong XP.

J Mol Biol. 2007 Nov 23;374(2):365-73. Epub 2007 Sep 20.

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