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Items: 6

1.

Blocking CXCR4 alleviates desmoplasia, increases T-lymphocyte infiltration, and improves immunotherapy in metastatic breast cancer.

Chen IX, Chauhan VP, Posada J, Ng MR, Wu MW, Adstamongkonkul P, Huang P, Lindeman N, Langer R, Jain RK.

Proc Natl Acad Sci U S A. 2019 Jan 30. pii: 201815515. doi: 10.1073/pnas.1815515116. [Epub ahead of print]

PMID:
30700545
2.

TRPM7 senses oxidative stress to release Zn2+ from unique intracellular vesicles.

Abiria SA, Krapivinsky G, Sah R, Santa-Cruz AG, Chaudhuri D, Zhang J, Adstamongkonkul P, DeCaen PG, Clapham DE.

Proc Natl Acad Sci U S A. 2017 Jul 25;114(30):E6079-E6088. doi: 10.1073/pnas.1707380114. Epub 2017 Jul 10.

3.

Nanoparticles that do not adhere to mucus provide uniform and long-lasting drug delivery to airways following inhalation.

Schneider CS, Xu Q, Boylan NJ, Chisholm J, Tang BC, Schuster BS, Henning A, Ensign LM, Lee E, Adstamongkonkul P, Simons BW, Wang SS, Gong X, Yu T, Boyle MP, Suk JS, Hanes J.

Sci Adv. 2017 Apr 5;3(4):e1601556. doi: 10.1126/sciadv.1601556. eCollection 2017 Apr.

4.

Angiotensin inhibition enhances drug delivery and potentiates chemotherapy by decompressing tumour blood vessels.

Chauhan VP, Martin JD, Liu H, Lacorre DA, Jain SR, Kozin SV, Stylianopoulos T, Mousa AS, Han X, Adstamongkonkul P, Popović Z, Huang P, Bawendi MG, Boucher Y, Jain RK.

Nat Commun. 2013;4:2516. doi: 10.1038/ncomms3516.

5.

Use of single-site-functionalized PEG dendrons to prepare gene vectors that penetrate human mucus barriers.

Kim AJ, Boylan NJ, Suk JS, Hwangbo M, Yu T, Schuster BS, Cebotaru L, Lesniak WG, Oh JS, Adstamongkonkul P, Choi AY, Kannan RM, Hanes J.

Angew Chem Int Ed Engl. 2013 Apr 2;52(14):3985-8. doi: 10.1002/anie.201208556. Epub 2013 Mar 4. No abstract available.

6.

Enhancement of airway gene transfer by DNA nanoparticles using a pH-responsive block copolymer of polyethylene glycol and poly-L-lysine.

Boylan NJ, Kim AJ, Suk JS, Adstamongkonkul P, Simons BW, Lai SK, Cooper MJ, Hanes J.

Biomaterials. 2012 Mar;33(7):2361-71. doi: 10.1016/j.biomaterials.2011.11.080. Epub 2011 Dec 17.

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