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Items: 1 to 20 of 27

1.

Chiral Plasmonic Fields Probe Structural Order of Biointerfaces.

Kelly C, Tullius R, Lapthorn AJ, Gadegaard N, Cooke G, Barron LD, Karimullah AS, Rotello VM, Kadodwala M.

J Am Chem Soc. 2018 Jul 11;140(27):8509-8517. doi: 10.1021/jacs.8b03634. Epub 2018 Jun 29.

2.

Superchiral Plasmonic Phase Sensitivity for Fingerprinting of Protein Interface Structure.

Tullius R, Platt GW, Khosravi Khorashad L, Gadegaard N, Lapthorn AJ, Rotello VM, Cooke G, Barron LD, Govorov AO, Karimullah AS, Kadodwala M.

ACS Nano. 2017 Dec 26;11(12):12049-12056. doi: 10.1021/acsnano.7b04698. Epub 2017 Dec 15.

PMID:
29220155
3.

Spectrum of Slow and Super-Slow (Picosecond to Nanosecond) Water Dynamics around Organic and Biological Solutes.

Ramakrishnan G, González-Jiménez M, Lapthorn AJ, Wynne K.

J Phys Chem Lett. 2017 Jul 6;8(13):2964-2970. doi: 10.1021/acs.jpclett.7b01127. Epub 2017 Jun 15.

4.

The molecular relationship between antigenic domains and epitopes on hCG.

Berger P, Lapthorn AJ.

Mol Immunol. 2016 Aug;76:134-45. doi: 10.1016/j.molimm.2016.06.015. Epub 2016 Jul 21. Review.

PMID:
27450517
5.

Observation of coherent delocalized phonon-like modes in DNA under physiological conditions.

González-Jiménez M, Ramakrishnan G, Harwood T, Lapthorn AJ, Kelly SM, Ellis EM, Wynne K.

Nat Commun. 2016 Jun 1;7:11799. doi: 10.1038/ncomms11799.

6.

Standardization of Epitopes for Human Chorionic Gonadotropin (hCG) Immunoassays.

Berger P, Lapthorn AJ.

Curr Med Chem. 2016;23(30):3481-3494. Review.

PMID:
27237818
7.

Spatial control of chemical processes on nanostructures through nano-localized water heating.

Jack C, Karimullah AS, Tullius R, Khorashad LK, Rodier M, Fitzpatrick B, Barron LD, Gadegaard N, Lapthorn AJ, Rotello VM, Cooke G, Govorov AO, Kadodwala M.

Nat Commun. 2016 Mar 10;7:10946. doi: 10.1038/ncomms10946.

8.

Terahertz underdamped vibrational motion governs protein-ligand binding in solution.

Turton DA, Senn HM, Harwood T, Lapthorn AJ, Ellis EM, Wynne K.

Nat Commun. 2014 Jun 3;5:3999. doi: 10.1038/ncomms4999.

PMID:
24893252
9.

The diversity of microbial aldo/keto reductases from Escherichia coli K12.

Lapthorn AJ, Zhu X, Ellis EM.

Chem Biol Interact. 2013 Feb 25;202(1-3):168-77. doi: 10.1016/j.cbi.2012.10.008. Epub 2012 Oct 24.

PMID:
23103600
10.

Tetrahydrobenzothiophene derivatives: conformationally restricted inhibitors of type II dehydroquinase.

Paz S, Tizón L, Otero JM, Llamas-Saiz AL, Fox GC, van Raaij MJ, Lamb H, Hawkins AR, Lapthorn AJ, Castedo L, González-Bello C.

ChemMedChem. 2011 Feb 7;6(2):266-72. doi: 10.1002/cmdc.201000343. Epub 2010 Nov 10. No abstract available.

PMID:
21275050
11.

Synthesis and evaluation of potent ene-yne inhibitors of type II dehydroquinases as tuberculosis drug leads.

Tran AT, Cergol KM, West NP, Randall EJ, Britton WJ, Bokhari SA, Ibrahim M, Lapthorn AJ, Payne RJ.

ChemMedChem. 2011 Feb 7;6(2):262-5. doi: 10.1002/cmdc.201000399. Epub 2010 Nov 4. No abstract available.

PMID:
21275049
12.

Design, synthesis, and structural studies on potent biaryl inhibitors of type II dehydroquinases.

Payne RJ, Riboldi-Tunnicliffe A, Kerbarh O, Abell AD, Lapthorn AJ, Abell C.

ChemMedChem. 2007 Jul;2(7):1010-3. No abstract available.

PMID:
17487901
13.

Nanomolar competitive inhibitors of Mycobacterium tuberculosis and Streptomyces coelicolor type II dehydroquinase.

Prazeres VF, Sánchez-Sixto C, Castedo L, Lamb H, Hawkins AR, Riboldi-Tunnicliffe A, Coggins JR, Lapthorn AJ, González-Bello C.

ChemMedChem. 2007 Feb;2(2):194-207.

PMID:
17245805
14.

Application of a new vector system for efficient protein purification in the crystallization of PA5104/ORF from Pseudomonas aeruginosa.

Lohkamp B, Paterson NG, Lapthorn AJ.

J Struct Biol. 2006 Jul;155(1):111-3. Epub 2006 Apr 25.

PMID:
16713297
15.

Crystal structures of Helicobacter pylori type II dehydroquinase inhibitor complexes: new directions for inhibitor design.

Robinson DA, Stewart KA, Price NC, Chalk PA, Coggins JR, Lapthorn AJ.

J Med Chem. 2006 Feb 23;49(4):1282-90.

PMID:
16480265
16.

Crystal structure of mouse succinic semialdehyde reductase AKR7A5: structural basis for substrate specificity.

Zhu X, Lapthorn AJ, Ellis EM.

Biochemistry. 2006 Feb 14;45(6):1562-70.

PMID:
16460003
17.

Rational design of new bifunctional inhibitors of type II dehydroquinase.

Toscano MD, Stewart KA, Coggins JR, Lapthorn AJ, Abell C.

Org Biomol Chem. 2005 Sep 7;3(17):3102-4. Epub 2005 Aug 1.

PMID:
16106291
18.

(1R,4S,5R)-3-Fluoro-1,4,5-trihydroxy-2-cyclohexene-1-carboxylic acid: the fluoro analogue of the enolate intermediate in the reaction catalyzed by type II dehydroquinases.

Frederickson M, Roszak AW, Coggins JR, Lapthorn AJ, Abell C.

Org Biomol Chem. 2004 Jun 7;2(11):1592-6. Epub 2004 May 6.

PMID:
15162210
19.

The structure of Escherichia coli ATP-phosphoribosyltransferase: identification of substrate binding sites and mode of AMP inhibition.

Lohkamp B, McDermott G, Campbell SA, Coggins JR, Lapthorn AJ.

J Mol Biol. 2004 Feb 6;336(1):131-44.

PMID:
14741209
20.

Effects of salts on the function and conformational stability of shikimate kinase.

Cerasoli E, Kelly SM, Coggins JR, Lapthorn AJ, Clarke DT, Price NC.

Biochim Biophys Acta. 2003 May 30;1648(1-2):43-54.

PMID:
12758146

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