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Items: 1 to 50 of 237

1.

PAI-1, A New Target for Controlling Lung-Cell Senescence and Fibrosis?

Adnot S, Breau M, Houssaini A.

Am J Respir Cell Mol Biol. 2019 Oct 17. doi: 10.1165/rcmb.2019-0341ED. [Epub ahead of print] No abstract available.

PMID:
31622556
2.

[Nursing care and personalised care and prevention of a vulnerable public].

Hyzard S, Adnot S, Neveu J, Queyron G, Ringaud C.

Rev Infirm. 2019 Oct;68(254):39-41. doi: 10.1016/j.revinf.2019.08.006. Review. French.

PMID:
31587852
3.

The antioxidant N-acetylcysteine protects from lung emphysema but induces lung adenocarcinoma in mice.

Breau M, Houssaini A, Lipskaia L, Abid S, Born E, Marcos E, Czibik G, Attwe A, Beaulieu D, Palazzo A, Flaman JM, Bourachot B, Collin G, Tran Van Nhieu J, Bernard D, Mechta-Grigoriou F, Adnot S.

JCI Insight. 2019 Oct 3;4(19). pii: 127647. doi: 10.1172/jci.insight.127647.

4.

CCR2/CCR5-mediated macrophage-smooth muscle cell crosstalk in pulmonary hypertension.

Abid S, Marcos E, Parpaleix A, Amsellem V, Breau M, Houssaini A, Vienney N, Lefevre M, Derumeaux G, Evans S, Hubeau C, Delcroix M, Quarck R, Adnot S, Lipskaia L.

Eur Respir J. 2019 Oct 10;54(4). pii: 1802308. doi: 10.1183/13993003.02308-2018. Print 2019 Oct.

PMID:
31320454
5.

The STATus of STAT3 in Lung Cell Senescence?

Adnot S, Lipskaia L, Bernard D.

Am J Respir Cell Mol Biol. 2019 Jul;61(1):5-6. doi: 10.1165/rcmb.2019-0013ED. No abstract available.

6.

Cardiac adenylyl cyclase overexpression precipitates and aggravates age-related myocardial dysfunction.

Mougenot N, Mika D, Czibik G, Marcos E, Abid S, Houssaini A, Vallin B, Guellich A, Mehel H, Sawaki D, Vandecasteele G, Fischmeister R, Hajjar RJ, Dubois-Randé JL, Limon I, Adnot S, Derumeaux G, Lipskaia L.

Cardiovasc Res. 2019 Oct 1;115(12):1778-1790. doi: 10.1093/cvr/cvy306.

PMID:
30605506
7.

Are Systemic Manifestations Ascribable to COPD in Smokers? A Structural Equation Modeling Approach.

Boyer L, Bastuji-Garin S, Chouaid C, Housset B, Le Corvoisier P, Derumeaux G, Boczkowski J, Maitre B, Adnot S, Audureau E.

Sci Rep. 2018 Jun 5;8(1):8569. doi: 10.1038/s41598-018-26766-x.

8.

Anthracycline cardiotoxicity: looking for new therapeutic approaches targeting cell senescence?

Abid S, Lipskaia L, Adnot S.

Cardiovasc Res. 2018 Aug 1;114(10):1304-1305. doi: 10.1093/cvr/cvy108. No abstract available.

PMID:
29718137
9.

Visceral Adipose Tissue Drives Cardiac Aging Through Modulation of Fibroblast Senescence by Osteopontin Production.

Sawaki D, Czibik G, Pini M, Ternacle J, Suffee N, Mercedes R, Marcelin G, Surenaud M, Marcos E, Gual P, Clément K, Hue S, Adnot S, Hatem SN, Tsuchimochi I, Yoshimitsu T, Hénégar C, Derumeaux G.

Circulation. 2018 Aug 21;138(8):809-822. doi: 10.1161/CIRCULATIONAHA.117.031358.

PMID:
29500246
10.

New Nitric Oxide Donor NCX 1443: Therapeutic Effects on Pulmonary Hypertension in the SAD Mouse Model of Sickle Cell Disease.

Abid S, Kebe K, Houssaïni A, Tomberli F, Marcos E, Bizard E, Breau M, Parpaleix A, Tissot CM, Maitre B, Lipskaia L, Derumeaux G, Bastia E, Mekontso-Dessap A, Adnot S.

J Cardiovasc Pharmacol. 2018 May;71(5):283-292. doi: 10.1097/FJC.0000000000000570.

PMID:
29438213
11.

mTOR pathway activation drives lung cell senescence and emphysema.

Houssaini A, Breau M, Kebe K, Abid S, Marcos E, Lipskaia L, Rideau D, Parpaleix A, Huang J, Amsellem V, Vienney N, Validire P, Maitre B, Attwe A, Lukas C, Vindrieux D, Boczkowski J, Derumeaux G, Pende M, Bernard D, Meiners S, Adnot S.

JCI Insight. 2018 Feb 8;3(3). pii: 93203. doi: 10.1172/jci.insight.93203. eCollection 2018 Feb 8.

12.

Beclin1 circulating levels and accelerated aging markers in COPD.

Schlemmer F, Boyer L, Soumagne T, Ridoux A, Chouaid C, Maitre B, Lanone S, Adnot S, Audureau E, Boczkowski J.

Cell Death Dis. 2018 Feb 5;9(2):156. doi: 10.1038/s41419-017-0178-1. No abstract available.

13.

mTOR: A Key to Both Pulmonary Vessel Remodeling and Right Ventricular Function in Pulmonary Arterial Hypertension?

Houssaini A, Adnot S.

Am J Respir Cell Mol Biol. 2017 Nov;57(5):509-511. doi: 10.1165/rcmb.2017-0245ED. No abstract available.

PMID:
29090958
14.

Impaired humoral and cellular immune responses to influenza vaccination in chronic obstructive pulmonary disease patients.

Parpaleix A, Boyer L, Wiedemann A, Lacabaratz C, Margarit L, Enouf V, Le Corvoisier P, Lino A, Covali-Noroc A, Housset B, Chouaid C, Maitre B, Lévy Y, Lelièvre JD, Adnot S.

J Allergy Clin Immunol. 2017 Dec;140(6):1754-1757.e6. doi: 10.1016/j.jaci.2017.07.038. Epub 2017 Sep 7. No abstract available.

PMID:
28889955
15.

Smoking, telomere length and lung function decline: a longitudinal population-based study.

Andujar P, Courbon D, Bizard E, Marcos E, Adnot S, Boyer L, Demoly P, Jarvis D, Neukirch C, Pin I, Thabut G, Boczkowski J, Leynaert B.

Thorax. 2018 Mar;73(3):283-285. doi: 10.1136/thoraxjnl-2017-210294. Epub 2017 Jul 19.

16.

Middle age exacerbates acute respiratory distress syndrome in a double hit murine model.

Voiriot G, Contou D, Tran Van Nhieu J, Amsellem V, Marcos E, Latiri M, Adnot S, Maitre B, Mekontso Dessap A.

Exp Gerontol. 2017 Oct 1;96:146-154. doi: 10.1016/j.exger.2017.06.022. Epub 2017 Jul 1.

PMID:
28676373
17.

Interleukin-6 displays lung anti-inflammatory properties and exerts protective hemodynamic effects in a double-hit murine acute lung injury.

Voiriot G, Razazi K, Amsellem V, Tran Van Nhieu J, Abid S, Adnot S, Mekontso Dessap A, Maitre B.

Respir Res. 2017 Apr 19;18(1):64. doi: 10.1186/s12931-017-0553-6.

18.

Investigating hyperventilation syndrome in patients suffering from empty nose syndrome.

Mangin D, Bequignon E, Zerah-Lancner F, Isabey D, Louis B, Adnot S, Papon JF, Coste A, Boyer L, Devars du Mayne M.

Laryngoscope. 2017 Sep;127(9):1983-1988. doi: 10.1002/lary.26599. Epub 2017 Apr 13.

PMID:
28407251
19.

Telomere attrition in sickle cell anemia.

Mekontso Dessap A, Cecchini J, Chaar V, Marcos E, Habibi A, Bartolucci P, Ghaleh B, Galacteros F, Adnot S.

Am J Hematol. 2017 Jun;92(6):E112-E114. doi: 10.1002/ajh.24721. Epub 2017 Apr 18. No abstract available.

20.

Roles for the CX3CL1/CX3CR1 and CCL2/CCR2 Chemokine Systems in Hypoxic Pulmonary Hypertension.

Amsellem V, Abid S, Poupel L, Parpaleix A, Rodero M, Gary-Bobo G, Latiri M, Dubois-Rande JL, Lipskaia L, Combadiere C, Adnot S.

Am J Respir Cell Mol Biol. 2017 May;56(5):597-608. doi: 10.1165/rcmb.2016-0201OC.

PMID:
28125278
21.

Short-term high-fat diet compromises myocardial function: a radial strain rate imaging study.

Ternacle J, Wan F, Sawaki D, Surenaud M, Pini M, Mercedes R, Ernande L, Audureau E, Dubois-Rande JL, Adnot S, Hue S, Czibik G, Derumeaux G.

Eur Heart J Cardiovasc Imaging. 2017 Nov 1;18(11):1283-1291. doi: 10.1093/ehjci/jew316.

PMID:
28062567
22.

Lack of information received by a French female cohort regarding prevention against exposure to reprotoxic agents during pregnancy.

Chabert MC, Perrin J, Berbis J, Bretelle F, Adnot S, Courbiere B.

Eur J Obstet Gynecol Reprod Biol. 2016 Oct;205:15-20. doi: 10.1016/j.ejogrb.2016.07.504. Epub 2016 Aug 3. Review.

PMID:
27552174
23.

A pilot study about infertile men's awareness of their reprotoxic exposures and the intervention of occupational medicine to assess them.

Christiaens A, Sari-Minodier I, Tardieu S, Ianos O, Adnot S, Courbiere B, Perrin J.

Basic Clin Androl. 2016 Aug 10;26:9. doi: 10.1186/s12610-016-0036-5. eCollection 2016.

24.

Osteopontin, a Key Mediator Expressed by Senescent Pulmonary Vascular Cells in Pulmonary Hypertension.

Saker M, Lipskaia L, Marcos E, Abid S, Parpaleix A, Houssaini A, Validire P, Girard P, Noureddine H, Boyer L, Vienney N, Amsellem V, Marguerit L, Maitre B, Derumeaux G, Dubois-Rande JL, Jourdan-Lesaux C, Delcroix M, Quarck R, Adnot S.

Arterioscler Thromb Vasc Biol. 2016 Sep;36(9):1879-90. doi: 10.1161/ATVBAHA.116.307839. Epub 2016 Jul 21.

PMID:
27444202
25.

Role of interleukin-1 receptor 1/MyD88 signalling in the development and progression of pulmonary hypertension.

Parpaleix A, Amsellem V, Houssaini A, Abid S, Breau M, Marcos E, Sawaki D, Delcroix M, Quarck R, Maillard A, Couillin I, Ryffel B, Adnot S.

Eur Respir J. 2016 Aug;48(2):470-83. doi: 10.1183/13993003.01448-2015. Epub 2016 Jul 13.

26.

Telomere Shortening in Middle-Aged Men with Sleep-disordered Breathing.

Boyer L, Audureau E, Margarit L, Marcos E, Bizard E, Le Corvoisier P, Macquin-Mavier I, Derumeaux G, Damy T, Drouot X, Covali-Noroc A, Boczkowski J, Bastuji-Garin S, Adnot S.

Ann Am Thorac Soc. 2016 Jul;13(7):1136-43. doi: 10.1513/AnnalsATS.201510-718OC.

PMID:
27163410
27.

Prevalence, Severity, and Prognostic Value of Sleep Apnea Syndromes in Cardiac Amyloidosis.

Bodez D, Guellich A, Kharoubi M, Covali-Noroc A, Tissot CM, Guendouz S, Hittinger L, Dubois-Randé JL, Lefaucheur JP, Planté-Bordeneuve V, Adnot S, Boyer L, Damy T.

Sleep. 2016 Jul 1;39(7):1333-41. doi: 10.5665/sleep.5958.

28.

Selective Tuberous Sclerosis Complex 1 Gene Deletion in Smooth Muscle Activates Mammalian Target of Rapamycin Signaling and Induces Pulmonary Hypertension.

Houssaini A, Abid S, Derumeaux G, Wan F, Parpaleix A, Rideau D, Marcos E, Kebe K, Czibik G, Sawaki D, Treins C, Dubois-Randé JL, Li Z, Amsellem V, Lipskaia L, Pende M, Adnot S.

Am J Respir Cell Mol Biol. 2016 Sep;55(3):352-67. doi: 10.1165/rcmb.2015-0339OC.

PMID:
26991739
29.

Extracellular Calpain/Calpastatin Balance Is Involved in the Progression of Pulmonary Hypertension.

Wan F, Letavernier E, Abid S, Houssaini A, Czibik G, Marcos E, Rideau D, Parpaleix A, Lipskaia L, Amsellem V, Gellen B, Sawaki D, Derumeaux G, Dubois-Randé JL, Delcroix M, Quarck R, Baud L, Adnot S.

Am J Respir Cell Mol Biol. 2016 Sep;55(3):337-51. doi: 10.1165/rcmb.2015-0257OC.

PMID:
26974350
30.

Axial stretch-dependent cation entry in dystrophic cardiomyopathy: Involvement of several TRPs channels.

Aguettaz E, Lopez JJ, Krzesiak A, Lipskaia L, Adnot S, Hajjar RJ, Cognard C, Constantin B, Sebille S.

Cell Calcium. 2016 Apr;59(4):145-155. doi: 10.1016/j.ceca.2016.01.001. Epub 2016 Jan 6.

31.

Apnea-hypopnea and desaturations in heart failure with reduced ejection fraction: Are we aiming at the right target?

Gellen B, Canouï-Poitrine F, Boyer L, Drouot X, Le Thuaut A, Bodez D, Covali-Noroc A, D'ortho MP, Guendouz S, Rappeneau S, Kharoubi M, Dubois-Rande JL, Hittinger L, Adnot S, Bastuji-Garin S, Damy T.

Int J Cardiol. 2016 Jan 15;203:1022-8. doi: 10.1016/j.ijcard.2015.11.108. Epub 2015 Nov 18.

PMID:
26630630
32.

Haematological determinants of cardiac involvement in adults with sickle cell disease.

Damy T, Bodez D, Habibi A, Guellich A, Rappeneau S, Inamo J, Guendouz S, Gellen-Dautremer J, Pissard S, Loric S, Wagner-Ballon O, Godeau B, Adnot S, Dubois-Randé JL, Hittinger L, Galactéros F, Bartolucci P.

Eur Heart J. 2016 Apr 7;37(14):1158-1167. doi: 10.1093/eurheartj/ehv555. Epub 2015 Oct 29.

PMID:
26516176
33.

Calpastatin overexpression impairs postinfarct scar healing in mice by compromising reparative immune cell recruitment and activation.

Wan F, Letavernier E, Le Saux CJ, Houssaini A, Abid S, Czibik G, Sawaki D, Marcos E, Dubois-Rande JL, Baud L, Adnot S, Derumeaux G, Gellen B.

Am J Physiol Heart Circ Physiol. 2015 Dec 1;309(11):H1883-93. doi: 10.1152/ajpheart.00594.2015. Epub 2015 Oct 9.

34.

Sleep-disordered breathing in chronic heart failure: development and validation of a clinical screening score.

Parisot J, Damy T, Gellen B, Covali-Noroc A, Bodez D, Rappeneau S, Guellich A, Adnot S, Bastuji-Garin S, Hittinger L, d'Ortho MP, Boyer L, Canouï-Poitrine F.

Sleep Med. 2015 Sep;16(9):1094-101. doi: 10.1016/j.sleep.2014.11.022. Epub 2015 Mar 30.

PMID:
26298785
35.

Dominant negative Ras attenuates pathological ventricular remodeling in pressure overload cardiac hypertrophy.

Ramos-Kuri M, Rapti K, Mehel H, Zhang S, Dhandapany PS, Liang L, García-Carrancá A, Bobe R, Fischmeister R, Adnot S, Lebeche D, Hajjar RJ, Lipskaia L, Chemaly ER.

Biochim Biophys Acta. 2015 Nov;1853(11 Pt A):2870-84. doi: 10.1016/j.bbamcr.2015.08.006. Epub 2015 Aug 8. Erratum in: Biochim Biophys Acta. 2016 Apr;1863(4):785.

36.

Telomere Dysfunction and Cell Senescence in Chronic Lung Diseases: Therapeutic Potential.

Adnot S, Amsellem V, Boyer L, Marcos E, Saker M, Houssaini A, Kebe K, Dagouassat M, Lipskaia L, Boczkowski J.

Pharmacol Ther. 2015 Sep;153:125-34. doi: 10.1016/j.pharmthera.2015.06.007. Epub 2015 Jun 18. Review.

PMID:
26096607
37.

Regulation of immunoproteasome function in the lung.

Keller IE, Vosyka O, Takenaka S, Kloß A, Dahlmann B, Willems LI, Verdoes M, Overkleeft HS, Marcos E, Adnot S, Hauck SM, Ruppert C, Günther A, Herold S, Ohno S, Adler H, Eickelberg O, Meiners S.

Sci Rep. 2015 May 19;5:10230. doi: 10.1038/srep10230.

38.

Aging-related systemic manifestations in COPD patients and cigarette smokers.

Boyer L, Chouaïd C, Bastuji-Garin S, Marcos E, Margarit L, Le Corvoisier P, Vervoitte L, Hamidou L, Frih L, Audureau E, Covali-Noroc A, Andujar P, Saakashvili Z, Lino A, Ghaleh B, Hue S, Derumeaux G, Housset B, Dubois-Randé JL, Boczkowski J, Maitre B, Adnot S.

PLoS One. 2015 Mar 18;10(3):e0121539. doi: 10.1371/journal.pone.0121539. eCollection 2015.

39.

Endothelial-to-mesenchymal transition in pulmonary hypertension.

Ranchoux B, Antigny F, Rucker-Martin C, Hautefort A, Péchoux C, Bogaard HJ, Dorfmüller P, Remy S, Lecerf F, Planté S, Chat S, Fadel E, Houssaini A, Anegon I, Adnot S, Simonneau G, Humbert M, Cohen-Kaminsky S, Perros F.

Circulation. 2015 Mar 17;131(11):1006-18. doi: 10.1161/CIRCULATIONAHA.114.008750. Epub 2015 Jan 15.

PMID:
25593290
40.

Senescent Cells Contribute to the Physiological Remodeling of Aged Lungs.

Calhoun C, Shivshankar P, Saker M, Sloane LB, Livi CB, Sharp ZD, Orihuela CJ, Adnot S, White ES, Richardson A, Le Saux CJ.

J Gerontol A Biol Sci Med Sci. 2016 Feb;71(2):153-60. doi: 10.1093/gerona/glu241. Epub 2015 Jan 7.

41.

Role for telomerase in pulmonary hypertension.

Mouraret N, Houssaïni A, Abid S, Quarck R, Marcos E, Parpaleix A, Gary-Bobo G, Dubois-Randé JL, Derumeaux G, Boczkowski J, Delcroix M, Blasco MA, Lipskaia L, Amsellem V, Adnot S.

Circulation. 2015 Feb 24;131(8):742-755. doi: 10.1161/CIRCULATIONAHA.114.013258. Epub 2014 Dec 30.

42.

[Cellular senescence and pulmonary disease: COPD as an example].

Boyer L, Savale L, Boczkowski J, Adnot S.

Rev Mal Respir. 2014 Dec;31(10):893-902. doi: 10.1016/j.rmr.2014.07.015. Epub 2014 Nov 8. Review. French.

PMID:
25496787
43.

Expression of sarco (endo) plasmic reticulum calcium ATPase (SERCA) system in normal mouse cardiovascular tissues, heart failure and atherosclerosis.

Lipskaia L, Keuylian Z, Blirando K, Mougenot N, Jacquet A, Rouxel C, Sghairi H, Elaib Z, Blaise R, Adnot S, Hajjar RJ, Chemaly ER, Limon I, Bobe R.

Biochim Biophys Acta. 2014 Nov;1843(11):2705-18. doi: 10.1016/j.bbamcr.2014.08.002. Epub 2014 Aug 7.

44.

CCR5 as a treatment target in pulmonary arterial hypertension.

Amsellem V, Lipskaia L, Abid S, Poupel L, Houssaini A, Quarck R, Marcos E, Mouraret N, Parpaleix A, Bobe R, Gary-Bobo G, Saker M, Dubois-Randé JL, Gladwin MT, Norris KA, Delcroix M, Combadière C, Adnot S.

Circulation. 2014 Sep 9;130(11):880-891. doi: 10.1161/CIRCULATIONAHA.114.010757. Epub 2014 Jul 3.

45.

Pulmonary hypertension and emphysema: cure targeting a common cause?

Adnot S, Kawut SM.

Am J Respir Crit Care Med. 2014 Jun 1;189(11):1291-2. doi: 10.1164/rccm.201404-0784ED. No abstract available.

PMID:
24881931
46.

[Cell senescence and pathophysiology of chronic lung diseases: role in chronic obstructive pulmonary disease].

Adnot S.

Bull Acad Natl Med. 2014 Apr-May;198(4-5):659-71. Review. French.

PMID:
26753399
47.

P21-dependent protective effects of a carbon monoxide-releasing molecule-3 in pulmonary hypertension.

Abid S, Houssaïni A, Mouraret N, Marcos E, Amsellem V, Wan F, Dubois-Randé JL, Derumeaux G, Boczkowski J, Motterlini R, Adnot S.

Arterioscler Thromb Vasc Biol. 2014 Feb;34(2):304-12. doi: 10.1161/ATVBAHA.113.302302. Epub 2013 Dec 12.

PMID:
24334871
48.

Serotonin transporter and serotonin receptors.

Adnot S, Houssaini A, Abid S, Marcos E, Amsellem V.

Handb Exp Pharmacol. 2013;218:365-80. doi: 10.1007/978-3-642-38664-0_15. Review.

PMID:
24092348
49.

Lung imaging during acute chest syndrome in sickle cell disease: computed tomography patterns and diagnostic accuracy of bedside chest radiograph.

Mekontso Dessap A, Deux JF, Habibi A, Abidi N, Godeau B, Adnot S, Brun-Buisson C, Rahmouni A, Galacteros F, Maitre B.

Thorax. 2014 Feb;69(2):144-51. doi: 10.1136/thoraxjnl-2013-203775. Epub 2013 Aug 7.

50.

Activation of lung p53 by Nutlin-3a prevents and reverses experimental pulmonary hypertension.

Mouraret N, Marcos E, Abid S, Gary-Bobo G, Saker M, Houssaini A, Dubois-Rande JL, Boyer L, Boczkowski J, Derumeaux G, Amsellem V, Adnot S.

Circulation. 2013 Apr 23;127(16):1664-76. doi: 10.1161/CIRCULATIONAHA.113.002434. Epub 2013 Mar 19.

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