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Items: 1 to 50 of 132

1.

Phase 1 Clinical Trial of a Conditionally Replication-Defective Human Cytomegalovirus (CMV) Vaccine in CMV-Seronegative Subjects.

Adler SP, Lewis N, Conlon A, Christiansen MP, Al-Ibrahim M, Rupp R, Fu TM, Bautista O, Tang H, Wang D, Fisher A, Culp T, Das R, Beck K, Tamms G, Musey L; V160-001 Study Group.

J Infect Dis. 2019 Jul 2;220(3):411-419. doi: 10.1093/infdis/jiz141.

PMID:
31535143
2.

A Replication Defective Human Cytomegalovirus Vaccine Elicits Humoral Immune Responses Analogous to Those with Natural Infection.

Liu Y, Freed DC, Li L, Tang A, Li F, Murray EM, Adler SP, McVoy MA, Rupp RE, Barrett D, Ye X, Zhang N, Beck K, Culp T, Das R, Song L, Vora K, Zhu H, Wang D, Espeseth AS, An Z, Musey L, Fu TM.

J Virol. 2019 Sep 11. pii: JVI.00747-19. doi: 10.1128/JVI.00747-19. [Epub ahead of print]

PMID:
31511385
3.

Immunization of Rabbits with Recombinant Human Cytomegalovirus Trimeric versus Monomeric gH/gL Protein Elicits Markedly Higher Titers of Antibody and Neutralization Activity.

Cui X, Cao Z, Wang S, Flora M, Adler SP, McVoy MA, Snapper CM.

Int J Mol Sci. 2019 Jun 28;20(13). pii: E3158. doi: 10.3390/ijms20133158.

4.

Pediatric roots of cytomegalovirus recurrence and memory inflation in the elderly.

Adler SP, Reddehase MJ.

Med Microbiol Immunol. 2019 Aug;208(3-4):323-328. doi: 10.1007/s00430-019-00609-6. Epub 2019 May 6. Review.

PMID:
31062089
5.

Role of pentamer complex-specific and IgG subclass 3 antibodies in HCMV hyperimmunoglobulin and standard intravenous IgG preparations.

Schampera MS, Arellano-Galindo J, Kagan KO, Adler SP, Jahn G, Hamprecht K.

Med Microbiol Immunol. 2019 Feb;208(1):69-80. doi: 10.1007/s00430-018-0558-x. Epub 2018 Sep 10.

PMID:
30203132
6.

Novel trimeric human cytomegalovirus glycoprotein B elicits a high-titer neutralizing antibody response.

Cui X, Cao Z, Wang S, Lee RB, Wang X, Murata H, Adler SP, McVoy MA, Snapper CM.

Vaccine. 2018 Sep 5;36(37):5580-5590. doi: 10.1016/j.vaccine.2018.07.056. Epub 2018 Aug 3.

7.

Prevention of maternal-fetal transmission of cytomegalovirus after primary maternal infection in the first trimester by biweekly hyperimmunoglobulin administration.

Kagan KO, Enders M, Schampera MS, Baeumel E, Hoopmann M, Geipel A, Berg C, Goelz R, De Catte L, Wallwiener D, Brucker S, Adler SP, Jahn G, Hamprecht K.

Ultrasound Obstet Gynecol. 2019 Mar;53(3):383-389. doi: 10.1002/uog.19164. Epub 2019 Feb 8.

PMID:
29947159
8.

Complement enhances in vitro neutralizing potency of antibodies to human cytomegalovirus glycoprotein B (gB) and immune sera induced by gB/MF59 vaccination.

Li F, Freed DC, Tang A, Rustandi RR, Troutman MC, Espeseth AS, Zhang N, An Z, McVoy M, Zhu H, Ha S, Wang D, Adler SP, Fu TM.

NPJ Vaccines. 2017 Dec 14;2:36. doi: 10.1038/s41541-017-0038-0. eCollection 2017.

9.

Fibroblast-adapted human CMV vaccines elicit predominantly conventional CD8 T cell responses in humans.

Murray SE, Nesterenko PA, Vanarsdall AL, Munks MW, Smart SM, Veziroglu EM, Sagario LC, Lee R, Claas FHJ, Doxiadis IIN, McVoy MA, Adler SP, Hill AB.

J Exp Med. 2017 Jul 3;214(7):1889-1899. doi: 10.1084/jem.20161988. Epub 2017 May 31.

10.

Cytomegalovirus Virions Shed in Urine Have a Reversible Block to Epithelial Cell Entry and Are Highly Resistant to Antibody Neutralization.

Cui X, Adler SP, Schleiss MR, Arav-Boger R, Demmler Harrison GJ, McVoy MA.

Clin Vaccine Immunol. 2017 Jun 5;24(6). pii: e00024-17. doi: 10.1128/CVI.00024-17. Print 2017 Jun.

11.

Genomic analysis of chimeric human cytomegalovirus vaccine candidates derived from strains Towne and Toledo.

Suárez NM, Lau B, Kemble GM, Lee R, Mocarski ES, Wilkinson GWG, Adler SP, McVoy MA, Davison AJ.

Virus Genes. 2017 Aug;53(4):650-655. doi: 10.1007/s11262-017-1452-0. Epub 2017 Apr 8.

12.

Neutralization of Diverse Human Cytomegalovirus Strains Conferred by Antibodies Targeting Viral gH/gL/pUL128-131 Pentameric Complex.

Ha S, Li F, Troutman MC, Freed DC, Tang A, Loughney JW, Wang D, Wang IM, Vlasak J, Nickle DC, Rustandi RR, Hamm M, DePhillips PA, Zhang N, McLellan JS, Zhu H, Adler SP, McVoy MA, An Z, Fu TM.

J Virol. 2017 Mar 13;91(7). pii: e02033-16. doi: 10.1128/JVI.02033-16. Print 2017 Apr 1.

13.

A Phase 1 Study of 4 Live, Recombinant Human Cytomegalovirus Towne/Toledo Chimera Vaccines in Cytomegalovirus-Seronegative Men.

Adler SP, Manganello AM, Lee R, McVoy MA, Nixon DE, Plotkin S, Mocarski E, Cox JH, Fast PE, Nesterenko PA, Murray SE, Hill AB, Kemble G.

J Infect Dis. 2016 Nov 1;214(9):1341-1348. Epub 2016 Aug 11.

14.

A cytomegalovirus DNA vaccine induces antibodies that block viral entry into fibroblasts and epithelial cells.

McVoy MA, Lee R, Saccoccio FM, Hartikka J, Smith LR, Mahajan R, Wang JB, Cui X, Adler SP.

Vaccine. 2015 Dec 16;33(51):7328-7336. doi: 10.1016/j.vaccine.2015.10.078. Epub 2015 Oct 24.

15.

Prevention of Maternal-Fetal Transmission of Cytomegalovirus.

Adler SP.

EBioMedicine. 2015 Aug 5;2(9):1027-8. doi: 10.1016/j.ebiom.2015.08.004. eCollection 2015 Sep. No abstract available.

16.

A high-affinity native human antibody neutralizes human cytomegalovirus infection of diverse cell types.

Kauvar LM, Liu K, Park M, DeChene N, Stephenson R, Tenorio E, Ellsworth SL, Tabata T, Petitt M, Tsuge M, Fang-Hoover J, Adler SP, Cui X, McVoy MA, Pereira L.

Antimicrob Agents Chemother. 2015 Mar;59(3):1558-68. doi: 10.1128/AAC.04295-14. Epub 2014 Dec 22.

17.

Prevalence of CMV infection among sexually active adolescents: a matched case-control study.

Foxworth MK 2nd, Wilms IR, Brookman RR, Crewe S, Adler SP.

Adolesc Health Med Ther. 2014 Apr 29;5:73-8. doi: 10.2147/AHMT.S60103. eCollection 2014.

18.

Primary maternal cytomegalovirus infections during pregnancy: association of CMV hyperimmune globulin with gestational age at birth and birth weight.

Nigro G, Capretti I, Manganello AM, Best AM, Adler SP.

J Matern Fetal Neonatal Med. 2015 Jan;28(2):168-71. doi: 10.3109/14767058.2014.907265. Epub 2014 Apr 25.

PMID:
24660895
19.

Herpesvirus-associated acute urticaria: an age matched case-control study.

Mareri A, Adler SP, Nigro G.

PLoS One. 2013 Dec 27;8(12):e85378. doi: 10.1371/journal.pone.0085378. eCollection 2013.

20.

Hyperimmunoglobulin for prevention of congenital cytomegalovirus disease.

Nigro G, Adler SP.

Clin Infect Dis. 2013 Dec;57 Suppl 4:S193-5. doi: 10.1093/cid/cit586.

PMID:
24257426
21.

Prevention of maternal-fetal transmission of cytomegalovirus.

Adler SP, Nigro G.

Clin Infect Dis. 2013 Dec;57 Suppl 4:S189-92. doi: 10.1093/cid/cit585.

PMID:
24257425
22.

Immunization to prevent congenital cytomegalovirus infection.

Adler SP.

Br Med Bull. 2013;107:57-68. doi: 10.1093/bmb/ldt023. Epub 2013 Aug 16. Review.

PMID:
23954939
23.

Antibody inhibition of human cytomegalovirus spread in epithelial cell cultures.

Cui X, Lee R, Adler SP, McVoy MA.

J Virol Methods. 2013 Sep;192(1-2):44-50. doi: 10.1016/j.jviromet.2013.04.015. Epub 2013 May 10.

24.

Editorial commentary: Primary maternal cytomegalovirus infection during pregnancy: do we have a treatment option?

Adler SP.

Clin Infect Dis. 2012 Aug;55(4):504-6. doi: 10.1093/cid/cis425. Epub 2012 Apr 26. No abstract available.

PMID:
22539663
25.

Fetal hyperechogenic bowel may indicate congenital cytomegalovirus disease responsive to immunoglobulin therapy.

Nigro G, Adler SP, Gatta E, Mascaretti G, Megaloikonomou A, La Torre R, Necozione S.

J Matern Fetal Neonatal Med. 2012 Nov;25(11):2202-5. doi: 10.3109/14767058.2012.684111. Epub 2012 May 18.

PMID:
22506668
26.

Neutralizing activity of immunoglobulin preparations.

Adler SP.

Transplantation. 2012 Feb 27;93(4):e14; author reply e14. doi: 10.1097/TP.0b013e3182416160. No abstract available.

PMID:
22314308
27.

Bacterial artificial chromosome clones of viruses comprising the towne cytomegalovirus vaccine.

Cui X, Adler SP, Davison AJ, Smith L, Habib el-SE, McVoy MA.

J Biomed Biotechnol. 2012;2012:428498. doi: 10.1155/2012/428498. Epub 2011 Nov 30.

28.

Immunoglobulin therapy of fetal cytomegalovirus infection occurring in the first half of pregnancy--a case-control study of the outcome in children.

Nigro G, Adler SP, Parruti G, Anceschi MM, Coclite E, Pezone I, Di Renzo GC.

J Infect Dis. 2012 Jan 15;205(2):215-27. doi: 10.1093/infdis/jir718. Epub 2011 Dec 2.

PMID:
22140265
29.

Infection with cytomegalovirus is not associated with premature mortality.

Adler SP, Best AM, Marshall B, Vetrovec GW.

Infect Dis Rep. 2011 Dec 5;3(2):e17. doi: 10.4081/idr.2011.e17. eCollection 2011 Sep 7. Review.

30.

Screening for cytomegalovirus during pregnancy.

Adler SP.

Infect Dis Obstet Gynecol. 2011;2011:1-9. doi: 10.1155/2011/942937. Epub 2011 Aug 9. Review.

31.

Neutralizing activity of saliva against cytomegalovirus.

Saccoccio FM, Gallagher MK, Adler SP, McVoy MA.

Clin Vaccine Immunol. 2011 Sep;18(9):1536-42. doi: 10.1128/CVI.05128-11. Epub 2011 Jul 27.

32.

Peptides from cytomegalovirus UL130 and UL131 proteins induce high titer antibodies that block viral entry into mucosal epithelial cells.

Saccoccio FM, Sauer AL, Cui X, Armstrong AE, Habib el-SE, Johnson DC, Ryckman BJ, Klingelhutz AJ, Adler SP, McVoy MA.

Vaccine. 2011 Mar 24;29(15):2705-11. doi: 10.1016/j.vaccine.2011.01.079. Epub 2011 Feb 22.

33.

Cytomegalovirus infections during pregnancy.

Nigro G, Adler SP.

Curr Opin Obstet Gynecol. 2011 Apr;23(2):123-8. doi: 10.1097/GCO.0b013e328342f1f6. Review.

PMID:
21157339
34.

Antibody treatment promotes compensation for human cytomegalovirus-induced pathogenesis and a hypoxia-like condition in placentas with congenital infection.

Maidji E, Nigro G, Tabata T, McDonagh S, Nozawa N, Shiboski S, Muci S, Anceschi MM, Aziz N, Adler SP, Pereira L.

Am J Pathol. 2010 Sep;177(3):1298-310. doi: 10.2353/ajpath.2010.091210. Epub 2010 Jul 22.

35.

Screening for cytomegalovirus during pregnancy.

Adler SP, Nigro G, Pereira L.

Am J Obstet Gynecol. 2010 Jul;203(1):e15; author reply e15-6. doi: 10.1016/j.ajog.2010.01.030. Epub 2010 Mar 15. No abstract available.

PMID:
20227052
37.

Findings and conclusions from CMV hyperimmune globulin treatment trials.

Adler SP, Nigro G.

J Clin Virol. 2009 Dec;46 Suppl 4:S54-7. doi: 10.1016/j.jcv.2009.08.017. Epub 2009 Sep 24. Review.

PMID:
19781985
38.

A CMV DNA vaccine primes for memory immune responses to live-attenuated CMV (Towne strain).

Jacobson MA, Adler SP, Sinclair E, Black D, Smith A, Chu A, Moss RB, Wloch MK.

Vaccine. 2009 Mar 4;27(10):1540-8. doi: 10.1016/j.vaccine.2009.01.006. Epub 2009 Jan 23.

PMID:
19168107
39.
40.

The frequency of pregnancy and exposure to cytomegalovirus infections among women with a young child in day care.

Marshall BC, Adler SP.

Am J Obstet Gynecol. 2009 Feb;200(2):163.e1-5. doi: 10.1016/j.ajog.2008.08.037. Epub 2008 Oct 9.

41.

Cytomegalovirus vaccines fail to induce epithelial entry neutralizing antibodies comparable to natural infection.

Cui X, Meza BP, Adler SP, McVoy MA.

Vaccine. 2008 Oct 23;26(45):5760-6. doi: 10.1016/j.vaccine.2008.07.092. Epub 2008 Aug 19.

42.

Cytomegalovirus infections among African-Americans.

Wilms IR, Best AM, Adler SP.

BMC Infect Dis. 2008 Aug 1;8:107. doi: 10.1186/1471-2334-8-107.

43.

Polymorphisms within human cytomegalovirus chemokine (UL146/UL147) and cytokine receptor genes (UL144) are not predictive of sequelae in congenitally infected children.

Heo J, Petheram S, Demmler G, Murph JR, Adler SP, Bale J, Sparer TE.

Virology. 2008 Aug 15;378(1):86-96. doi: 10.1016/j.virol.2008.05.002. Epub 2008 Jun 16. Erratum in: Virology. 2009 Jan 5;383(1):168-71.

44.

Regression of fetal cerebral abnormalities by primary cytomegalovirus infection following hyperimmunoglobulin therapy.

Nigro G, La Torre R, Pentimalli H, Taverna P, Lituania M, de Tejada BM, Adler SP.

Prenat Diagn. 2008 Jun;28(6):512-7. doi: 10.1002/pd.2013.

PMID:
18509871
45.

Human CMV vaccine trials: what if CMV caused a rash?

Adler SP.

J Clin Virol. 2008 Mar;41(3):231-6. Epub 2007 Dec 21. Review.

PMID:
18096431
46.

Humoral immunity targeting site I of antigenic domain 2 of glycoprotein B upon immunization with different cytomegalovirus candidate vaccines.

Axelsson F, Adler SP, Lamarre A, Ohlin M.

Vaccine. 2007 Dec 21;26(1):41-6. Epub 2007 Nov 9.

PMID:
18063447
47.

Knowledge and awareness of congenital cytomegalovirus among women.

Jeon J, Victor M, Adler SP, Arwady A, Demmler G, Fowler K, Goldfarb J, Keyserling H, Massoudi M, Richards K, Staras SA, Cannon MJ.

Infect Dis Obstet Gynecol. 2006;2006:80383.

48.

Cytomegalovirus infections.

Adler SP, Marshall B.

Pediatr Rev. 2007 Mar;28(3):92-100. Review. No abstract available.

PMID:
17332168
49.

Recent advances in the prevention and treatment of congenital cytomegalovirus infections.

Adler SP, Nigro G, Pereira L.

Semin Perinatol. 2007 Feb;31(1):10-8. Review.

PMID:
17317422
50.

Placental enlargement in women with primary maternal cytomegalovirus infection is associated with fetal and neonatal disease.

La Torre R, Nigro G, Mazzocco M, Best AM, Adler SP.

Clin Infect Dis. 2006 Oct 15;43(8):994-1000. Epub 2006 Sep 6.

PMID:
16983610

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