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A comparative epigenome analysis of gammaherpesviruses suggests cis-acting sequence features as critical mediators of rapid polycomb recruitment.

Günther T, Fröhlich J, Herrde C, Ohno S, Burkhardt L, Adler H, Grundhoff A.

PLoS Pathog. 2019 Oct 31;15(10):e1007838. doi: 10.1371/journal.ppat.1007838. [Epub ahead of print]


Common vole (Microtus arvalis) and bank vole (Myodes glareolus) derived permanent cell lines differ in their susceptibility and replication kinetics of animal and zoonotic viruses.

Binder F, Lenk M, Weber S, Stoek F, Dill V, Reiche S, Riebe R, Wernike K, Hoffmann D, Ziegler U, Adler H, Essbauer S, Ulrich RG.

J Virol Methods. 2019 Dec;274:113729. doi: 10.1016/j.jviromet.2019.113729. Epub 2019 Sep 9.


Intracerebral tuberculomas: A rare cause of seizure in an immunocompetent young male.

Vu K, Adler H, Gibbons E, Pearson J, Betz W.

IDCases. 2019 Aug 7;18:e00599. doi: 10.1016/j.idcr.2019.e00599. eCollection 2019.


Scientists with Hearing Loss Changing Perspectives in STEMM.

Adler HJ, Ratnanather JT, Steyger PS, Buran BN.

Acoust Today. 2019 Spring;15(1):66-70. No abstract available.


Pneumococcal Colonization in Healthy Adult Research Participants in the Conjugate Vaccine Era, United Kingdom, 2010-2017.

Adler H, Nikolaou E, Gould K, Hinds J, Collins AM, Connor V, Hales C, Hill H, Hyder-Wright AD, Zaidi SR, German EL, Gritzfeld JF, Mitsi E, Pojar S, Gordon SB, Roberts AP, Rylance J, Ferreira DM.

J Infect Dis. 2019 May 24;219(12):1989-1993. doi: 10.1093/infdis/jiz034.


"Novel" Triggers of Herpesvirus Reactivation and Their Potential Health Relevance.

Stoeger T, Adler H.

Front Microbiol. 2019 Jan 7;9:3207. doi: 10.3389/fmicb.2018.03207. eCollection 2018. No abstract available.


B cells latently infected with murine gammaherpesvirus 68 (MHV-68) are present in the mouse thymus-A step toward immune evasion?

Yamano T, Steinert M, Steer B, Klein L, Hammerschmidt W, Adler H.

Eur J Immunol. 2019 Feb;49(2):351-352. doi: 10.1002/eji.201847886. Epub 2018 Dec 10.


Endosomal Toll-Like Receptors 7 and 9 Cooperate in Detection of Murine Gammaherpesvirus 68 Infection.

Bussey KA, Murthy S, Reimer E, Chan B, Hatesuer B, Schughart K, Glaunsinger B, Adler H, Brinkmann MM.

J Virol. 2019 Jan 17;93(3). pii: e01173-18. doi: 10.1128/JVI.01173-18. Print 2019 Feb 1.


Inflammation induced by influenza virus impairs human innate immune control of pneumococcus.

Jochems SP, Marcon F, Carniel BF, Holloway M, Mitsi E, Smith E, Gritzfeld JF, Solórzano C, Reiné J, Pojar S, Nikolaou E, German EL, Hyder-Wright A, Hill H, Hales C, de Steenhuijsen Piters WAA, Bogaert D, Adler H, Zaidi S, Connor V, Gordon SB, Rylance J, Nakaya HI, Ferreira DM.

Nat Immunol. 2018 Dec;19(12):1299-1308. doi: 10.1038/s41590-018-0231-y. Epub 2018 Oct 29.


Corrigendum: Interleukin-2-Inducible T-Cell Kinase Deficiency-New Patients, New Insight?

Ghosh S, Drexler I, Bhatia S, Adler H, Gennery AR, Borkhardt A.

Front Immunol. 2018 Oct 1;9:2197. doi: 10.3389/fimmu.2018.02197. eCollection 2018.


Hands are vehicles for transmission of Streptococcus pneumoniae in novel controlled human infection study.

Connor V, German E, Pojar S, Mitsi E, Hales C, Nikolaou E, Hyder-Wright A, Adler H, Zaidi S, Hill H, Jochems SP, Burhan H, French N, Tobery T, Rylance J, Ferreira DM.

Eur Respir J. 2018 Oct 10;52(4). pii: 1800599. doi: 10.1183/13993003.00599-2018. Print 2018 Oct. No abstract available.


S100a4 Is Secreted by Alternatively Activated Alveolar Macrophages and Promotes Activation of Lung Fibroblasts in Pulmonary Fibrosis.

Zhang W, Ohno S, Steer B, Klee S, Staab-Weijnitz CA, Wagner D, Lehmann M, Stoeger T, Königshoff M, Adler H.

Front Immunol. 2018 Jun 1;9:1216. doi: 10.3389/fimmu.2018.01216. eCollection 2018.


Interleukin-2-Inducible T-Cell Kinase Deficiency-New Patients, New Insight?

Ghosh S, Drexler I, Bhatia S, Adler H, Gennery AR, Borkhardt A.

Front Immunol. 2018 May 8;9:979. doi: 10.3389/fimmu.2018.00979. eCollection 2018. Review. Erratum in: Front Immunol. 2018 Oct 01;9:2197.


Malnutrition risk is associated with hypoglycemia among general population admitted to internal medicine units. Results from the MENU study.

Leibovitz E, Adler H, Giryes S, Ditch M, Burg NF, Boaz M.

Eur J Clin Nutr. 2018 Jun;72(6):888-893. doi: 10.1038/s41430-018-0143-9. Epub 2018 Mar 27.


Qualitative differences in cellular immunogenicity elicited by hepatitis C virus T-Cell vaccines employing prime-boost regimens.

Tan WG, Zubkova I, Kachko A, Wells F, Adler H, Sutter G, Major ME.

PLoS One. 2017 Jul 21;12(7):e0181578. doi: 10.1371/journal.pone.0181578. eCollection 2017.


Community network for deaf scientists.

Adler HJ, Anbuhl KL, Atcherson SR, Barlow N, Brennan MA, Brigande JV, Buran BN, Fraenzer JT, Gale JE, Gallun FJ, Gluck SD, Goldsworthy RL, Heng J, Hight AE, Huyck JJ, Jacobson BD, Karasawa T, Kovačić D, Lim SR, Malone AK, Nolan LS, Pisano DV, Rao VRM, Raphael RM, Ratnanather JT, Reiss LAJ, Ruffin CV, Schwalje AT, Sinan M, Stahn P, Steyger PS, Tang SJ, Tejani VD, Wong V.

Science. 2017 Apr 28;356(6336):386-387. doi: 10.1126/science.aan2330. Epub 2017 Apr 27. No abstract available.


Pneumococcal Capsular Polysaccharide Immunity in the Elderly.

Adler H, Ferreira DM, Gordon SB, Rylance J.

Clin Vaccine Immunol. 2017 Jun 5;24(6). pii: e00004-17. doi: 10.1128/CVI.00004-17. Print 2017 Jun. Review.


Tuberculosis in HIV-infected South African children with complicated severe acute malnutrition.

Adler H, Archary M, Mahabeer P, LaRussa P, Bobat RA.

Int J Tuberc Lung Dis. 2017 Apr 1;21(4):438-445. doi: 10.5588/ijtld.16.0753.


Motor neurons control blood vessel patterning in the developing spinal cord.

Himmels P, Paredes I, Adler H, Karakatsani A, Luck R, Marti HH, Ermakova O, Rempel E, Stoeckli ET, Ruiz de Almodóvar C.

Nat Commun. 2017 Mar 6;8:14583. doi: 10.1038/ncomms14583.


Novel Analysis of Immune Cells from Nasal Microbiopsy Demonstrates Reliable, Reproducible Data for Immune Populations, and Superior Cytokine Detection Compared to Nasal Wash.

Jochems SP, Piddock K, Rylance J, Adler H, Carniel BF, Collins A, Gritzfeld JF, Hancock C, Hill H, Reiné J, Seddon A, Solórzano C, Sunny S, Trimble A, Wright AD, Zaidi S, Gordon SB, Ferreira DM.

PLoS One. 2017 Jan 20;12(1):e0169805. doi: 10.1371/journal.pone.0169805. eCollection 2017.


Nanoparticle exposure reactivates latent herpesvirus and restores a signature of acute infection.

Sattler C, Moritz F, Chen S, Steer B, Kutschke D, Irmler M, Beckers J, Eickelberg O, Schmitt-Kopplin P, Adler H, Stoeger T.

Part Fibre Toxicol. 2017 Jan 10;14(1):2. doi: 10.1186/s12989-016-0181-1.


Herpesviruses and Their Host Cells: A Successful Liaison.

Adler B, Sattler C, Adler H.

Trends Microbiol. 2017 Mar;25(3):229-241. doi: 10.1016/j.tim.2016.11.009. Epub 2016 Dec 9. Review.


The small noncoding RNAs (sncRNAs) of murine gammaherpesvirus 68 (MHV-68) are involved in regulating the latent-to-lytic switch in vivo.

Steer B, Strehle M, Sattler C, Bund D, Flach B, Stoeger T, Haas JG, Adler H.

Sci Rep. 2016 Aug 26;6:32128. doi: 10.1038/srep32128.


Noise-induced hearing loss: Neuropathic pain via Ntrk1 signaling.

Manohar S, Dahar K, Adler HJ, Dalian D, Salvi R.

Mol Cell Neurosci. 2016 Sep;75:101-12. doi: 10.1016/j.mcn.2016.07.005. Epub 2016 Jul 26.


Bacterial infections in HIV-infected children admitted with severe acute malnutrition in Durban, South Africa.

Archary M, Adler H, La Russa P, Mahabeer P, Bobat RA.

Paediatr Int Child Health. 2017 Feb;37(1):6-13. doi: 10.1080/20469047.2016.1198561. Epub 2016 Jul 4.


pH- and Metal Ion- Sensitive Hydrogels based on N-[2-(dimethylaminoethyl)acrylamide].

Nebhani L, Choudhary V, Adler HP, Kuckling D.

Polymers (Basel). 2016 Jun 15;8(6). pii: E233. doi: 10.3390/polym8060233.


CEACAM1-Mediated Inhibition of Virus Production.

Vitenshtein A, Weisblum Y, Hauka S, Halenius A, Oiknine-Djian E, Tsukerman P, Bauman Y, Bar-On Y, Stern-Ginossar N, Enk J, Ortenberg R, Tai J, Markel G, Blumberg RS, Hengel H, Jonjic S, Wolf DG, Adler H, Kammerer R, Mandelboim O.

Cell Rep. 2016 Jun 14;15(11):2331-9. doi: 10.1016/j.celrep.2016.05.036. Epub 2016 Jun 2.


Lamivudine Monotherapy: Experience of Medium-term Outcomes in HIV-infected Children Unable to Adhere to Triple Therapy.

Linder V, Goldswain C, Adler H, Carty C, Harper K, Jackson V, Lambert JS, Boon G.

Pediatr Infect Dis J. 2016 Jul;35(7):e199-205. doi: 10.1097/INF.0000000000001156.


Multiple Lytic Origins of Replication Are Required for Optimal Gammaherpesvirus Fitness In Vitro and In Vivo.

Sattler C, Steer B, Adler H.

PLoS Pathog. 2016 Mar 23;12(3):e1005510. doi: 10.1371/journal.ppat.1005510. eCollection 2016 Mar.


Prevention of Tumor Formation by Latent Gammaherpesvirus Infection.

Raffegerst S, Steer B, Hohloch M, Adler H.

PLoS One. 2015 Dec 29;10(12):e0145678. doi: 10.1371/journal.pone.0145678. eCollection 2015.


A PIECE OF MY MIND. A Piece of My Mind--Actually.

Adler HM.

JAMA. 2015 Oct 27;314(16):1693-4. doi: 10.1001/jama.2015.8429. No abstract available.


Regulation of 26S Proteasome Activity in Pulmonary Fibrosis.

Semren N, Welk V, Korfei M, Keller IE, Fernandez IE, Adler H, Günther A, Eickelberg O, Meiners S.

Am J Respir Crit Care Med. 2015 Nov 1;192(9):1089-101. doi: 10.1164/rccm.201412-2270OC.


Enhancement of Radiative Plasmon Decay by Hot Electron Tunneling.

Wang X, Braun K, Zhang D, Peisert H, Adler H, Chassé T, Meixner AJ.

ACS Nano. 2015 Aug 25;9(8):8176-83. doi: 10.1021/acsnano.5b02361. Epub 2015 Jul 29.


Superluminescence from an optically pumped molecular tunneling junction by injection of plasmon induced hot electrons.

Braun K, Wang X, Kern AM, Adler H, Peisert H, Chassé T, Zhang D, Meixner AJ.

Beilstein J Nanotechnol. 2015 May 4;6:1100-6. doi: 10.3762/bjnano.6.111. eCollection 2015.


Impaired glucose metabolism in HIV-infected pregnant women: a retrospective analysis.

Moore R, Adler H, Jackson V, Lawless M, Byrne M, Eogan M, Lambert JS.

Int J STD AIDS. 2016 Jun;27(7):581-5. doi: 10.1177/0956462415587625. Epub 2015 May 20.


Regulation of immunoproteasome function in the lung.

Keller IE, Vosyka O, Takenaka S, Kloß A, Dahlmann B, Willems LI, Verdoes M, Overkleeft HS, Marcos E, Adnot S, Hauck SM, Ruppert C, Günther A, Herold S, Ohno S, Adler H, Eickelberg O, Meiners S.

Sci Rep. 2015 May 19;5:10230. doi: 10.1038/srep10230.


Electronic structure at transition metal phthalocyanine-transition metal oxide interfaces: Cobalt phthalocyanine on epitaxial MnO films.

Glaser M, Peisert H, Adler H, Aygül U, Ivanovic M, Nagel P, Merz M, Schuppler S, Chassé T.

J Chem Phys. 2015 Mar 14;142(10):101918. doi: 10.1063/1.4907899.


Non-redundant and redundant roles of cytomegalovirus gH/gL complexes in host organ entry and intra-tissue spread.

Lemmermann NA, Krmpotic A, Podlech J, Brizic I, Prager A, Adler H, Karbach A, Wu Y, Jonjic S, Reddehase MJ, Adler B.

PLoS Pathog. 2015 Feb 6;11(2):e1004640. doi: 10.1371/journal.ppat.1004640. eCollection 2015 Feb.


Evasion of innate cytosolic DNA sensing by a gammaherpesvirus facilitates establishment of latent infection.

Sun C, Schattgen SA, Pisitkun P, Jorgensen JP, Hilterbrand AT, Wang LJ, West JA, Hansen K, Horan KA, Jakobsen MR, O'Hare P, Adler H, Sun R, Ploegh HL, Damania B, Upton JW, Fitzgerald KA, Paludan SR.

J Immunol. 2015 Feb 15;194(4):1819-31. doi: 10.4049/jimmunol.1402495. Epub 2015 Jan 16.


Attachment insecurity and obsessive-compulsive personality disorder among inpatients with serious mental illness.

Wiltgen A, Adler H, Smith R, Rufino K, Frazier C, Shepard C, Booker K, Simmons D, Richardson L, Allen JG, Fowler JC.

J Affect Disord. 2015 Mar 15;174:411-5. doi: 10.1016/j.jad.2014.12.011. Epub 2014 Dec 13.


Pancreatic metastasectomy: experience of the Irish National Surgical Centre for Pancreatic Cancer.

Redmond CE, Adler H, Heneghan HM, Kelly R, Swan N, Cantwell CP, Maguire D, Traynor O, Hoti E, Geoghegan JG, Conlon KC.

Ir J Med Sci. 2014 Dec;183(4):677-80. doi: 10.1007/s11845-014-1175-3. Epub 2014 Jul 24.


To the editor: Murine gammaherpesvirus 68 (MHV-68) escapes from NK-cell-mediated immune surveillance by a CEACAM1-mediated immune evasion mechanism.

Adler H, Steer B, Juskewitz E, Kammerer R.

Eur J Immunol. 2014 Aug;44(8):2521-2. doi: 10.1002/eji.201444593. Epub 2014 Jun 30. No abstract available.


The gammaherpesviruses Kaposi's sarcoma-associated herpesvirus and murine gammaherpesvirus 68 modulate the Toll-like receptor-induced proinflammatory cytokine response.

Bussey KA, Reimer E, Todt H, Denker B, Gallo A, Konrad A, Ottinger M, Adler H, Stürzl M, Brune W, Brinkmann MM.

J Virol. 2014 Aug;88(16):9245-59. doi: 10.1128/JVI.00841-14. Epub 2014 Jun 4.


Daclatasvir for the treatment of hepatitis C virus infection.

Adler H, Lambert JS.

Expert Rev Gastroenterol Hepatol. 2014 Sep;8(7):725-38. doi: 10.1586/17474124.2014.925798. Epub 2014 May 31. Review.


XIAP restricts TNF- and RIP3-dependent cell death and inflammasome activation.

Yabal M, Müller N, Adler H, Knies N, Groß CJ, Damgaard RB, Kanegane H, Ringelhan M, Kaufmann T, Heikenwälder M, Strasser A, Groß O, Ruland J, Peschel C, Gyrd-Hansen M, Jost PJ.

Cell Rep. 2014 Jun 26;7(6):1796-808. doi: 10.1016/j.celrep.2014.05.008. Epub 2014 May 29.


Clinical focus: infections in pregnancy.

Adler H, Lambert JS.

Hosp Pract (1995). 2014 Apr;42(2):108-24. doi: 10.3810/hp.2014.04.1109. Review.


Study on dicarboxylic acids in aerosol samples with capillary electrophoresis.

Adler H, Sirén H.

J Anal Methods Chem. 2014;2014:498168. doi: 10.1155/2014/498168. Epub 2014 Mar 9.


Management of ganciclovir-resistant cytomegalovirus retinitis in HIV infection in the era of antiretroviral therapy.

Adler H, De Gascun CF, McSweeney F, Acheson RW, Brannigan ET, Duffy M, Keegan DJ, Lambert JS.

Int J STD AIDS. 2014 Oct;25(11):827-9. doi: 10.1177/0956462414522773. Epub 2014 Feb 10.


Pancreatectomy for metastatic disease: a systematic review.

Adler H, Redmond CE, Heneghan HM, Swan N, Maguire D, Traynor O, Hoti E, Geoghegan JG, Conlon KC.

Eur J Surg Oncol. 2014 Apr;40(4):379-86. doi: 10.1016/j.ejso.2013.12.022. Epub 2014 Jan 15. Review.


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