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Items: 32


Mitochondrial Morphofunction in Mammalian Cells.

Bulthuis EP, Adjobo-Hermans MJW, Willems PHGM, Koopman WJH.

Antioxid Redox Signal. 2019 Jun 20;30(18):2066-2109. doi: 10.1089/ars.2018.7534. Epub 2018 Nov 29.


Red Blood Cell Homeostasis: Mechanisms and Effects of Microvesicle Generation in Health and Disease.

Leal JKF, Adjobo-Hermans MJW, Bosman GJCGM.

Front Physiol. 2018 Jun 8;9:703. doi: 10.3389/fphys.2018.00703. eCollection 2018. Review.


Correction: A FRET-based biosensor for measuring Gα13 activation in single cells.

Mastop M, Reinhard NR, Zuconelli CR, Terwey F, Gadella TWJ Jr, van Unen J, Adjobo-Hermans MJW, Goedhart J.

PLoS One. 2018 Apr 4;13(4):e0195649. doi: 10.1371/journal.pone.0195649. eCollection 2018.


A FRET-based biosensor for measuring Gα13 activation in single cells.

Mastop M, Reinhard NR, Zuconelli CR, Terwey F, Gadella TWJ Jr, van Unen J, Adjobo-Hermans MJW, Goedhart J.

PLoS One. 2018 Mar 5;13(3):e0193705. doi: 10.1371/journal.pone.0193705. eCollection 2018. Erratum in: PLoS One. 2018 Apr 4;13(4):e0195649.


Acetylcholinesterase provides new insights into red blood cell ageing in vivo and in vitro.

Freitas Leal JK, Adjobo-Hermans MJW, Brock R, Bosman GJCGM.

Blood Transfus. 2017 May;15(3):232-238. doi: 10.2450/2017.0370-16.


Tetraspanin microdomains control localized protein kinase C signaling in B cells.

Zuidscherwoude M, Dunlock VE, van den Bogaart G, van Deventer SJ, van der Schaaf A, van Oostrum J, Goedhart J, In 't Hout J, Hämmerling GJ, Tanaka S, Nadler A, Schultz C, Wright MD, Adjobo-Hermans MJW, van Spriel AB.

Sci Signal. 2017 May 9;10(478). pii: eaag2755. doi: 10.1126/scisignal.aag2755.


Linear Peptides in Intracellular Applications.

Zuconelli CR, Brock R, Adjobo-Hermans MJW.

Curr Med Chem. 2017;24(17):1862-1873. doi: 10.2174/0929867324666170508143523. Review.


Membrane permeation of arginine-rich cell-penetrating peptides independent of transmembrane potential as a function of lipid composition and membrane fluidity.

Wallbrecher R, Ackels T, Olea RA, Klein MJ, Caillon L, Schiller J, Bovée-Geurts PH, van Kuppevelt TH, Ulrich AS, Spehr M, Adjobo-Hermans MJW, Brock R.

J Control Release. 2017 Jun 28;256:68-78. doi: 10.1016/j.jconrel.2017.04.013. Epub 2017 Apr 12.


Effects of a human recombinant alkaline phosphatase during impaired mitochondrial function in human renal proximal tubule epithelial cells.

Peters E, Schirris T, van Asbeck AH, Gerretsen J, Eymael J, Ashikov A, Adjobo-Hermans MJ, Russel F, Pickkers P, Masereeuw R.

Eur J Pharmacol. 2017 Feb 5;796:149-157. doi: 10.1016/j.ejphar.2016.12.034. Epub 2016 Dec 22.


Identification of Short Hydrophobic Cell-Penetrating Peptides for Cytosolic Peptide Delivery by Rational Design.

Schmidt S, Adjobo-Hermans MJ, Kohze R, Enderle T, Brock R, Milletti F.

Bioconjug Chem. 2017 Feb 15;28(2):382-389. doi: 10.1021/acs.bioconjchem.6b00535. Epub 2016 Dec 14.


Red Blood Cell Homeostasis: Pharmacological Interventions to Explore Biochemical, Morphological and Mechanical Properties.

Cluitmans JC, Gevi F, Siciliano A, Matte A, Leal JK, De Franceschi L, Zolla L, Brock R, Adjobo-Hermans MJ, Bosman GJ.

Front Mol Biosci. 2016 Mar 29;3:10. doi: 10.3389/fmolb.2016.00010. eCollection 2016.


A microarray-based approach to evaluate the functional significance of protein-binding motifs.

Sinzinger MD, Chung YD, Adjobo-Hermans MJ, Brock R.

Anal Bioanal Chem. 2016 May;408(12):3177-84. doi: 10.1007/s00216-016-9382-6. Epub 2016 Feb 18.


Impaired primary mouse myotube formation on crosslinked type I collagen films is enhanced by laminin and entactin.

Grefte S, Adjobo-Hermans MJW, Versteeg EMM, Koopman WJH, Daamen WF.

Acta Biomater. 2016 Jan;30:265-276. doi: 10.1016/j.actbio.2015.11.009. Epub 2015 Nov 7.


Detecting Cytosolic Peptide Delivery with the GFP Complementation Assay in the Low Micromolar Range.

Schmidt S, Adjobo-Hermans MJ, Wallbrecher R, Verdurmen WP, Bovée-Geurts PH, van Oostrum J, Milletti F, Enderle T, Brock R.

Angew Chem Int Ed Engl. 2015 Dec 7;54(50):15105-8. doi: 10.1002/anie.201505913. Epub 2015 Oct 30.


Neuroacanthocytosis: Observations, Theories and Perspectives on the Origin and Significance of Acanthocytes.

Adjobo-Hermans MJ, Cluitmans JC, Bosman GJ.

Tremor Other Hyperkinet Mov (N Y). 2015 Aug 25;5:328. doi: 10.7916/D8VH5N2M. eCollection 2015. Review.


A Perspective on Studying G-Protein-Coupled Receptor Signaling with Resonance Energy Transfer Biosensors in Living Organisms.

van Unen J, Woolard J, Rinken A, Hoffmann C, Hill SJ, Goedhart J, Bruchas MR, Bouvier M, Adjobo-Hermans MJ.

Mol Pharmacol. 2015 Sep;88(3):589-95. doi: 10.1124/mol.115.098897. Epub 2015 May 13. Review.


A peptide-functionalized polymer as a minimal scaffold protein to enhance cluster formation in early T cell signal transduction.

Witsenburg JJ, Sinzinger MD, Stoevesandt O, Ruttekolk IR, Roth G, Adjobo-Hermans MJ, Brock R.

Chembiochem. 2015 Mar 2;16(4):602-10. doi: 10.1002/cbic.201402622. Epub 2015 Feb 6.


GqPCR-mediated signalling in the spotlight: from visualization towards dissection and quantification.

Jalink K, Adjobo-Hermans MJ.

Curr Pharm Biotechnol. 2014;15(10):893-915. Review.


Fast reversibility of dimeriser system enables quantification of signal molecule turnover.

Adjobo-Hermans MJ.

Chembiochem. 2014 Sep 22;15(14):2037-9. doi: 10.1002/cbic.201402294. Epub 2014 Aug 21.


Multivalent presentation of the cell-penetrating peptide nona-arginine on a linear scaffold strongly increases its membrane-perturbing capacity.

Chakrabarti A, Witsenburg JJ, Sinzinger MD, Richter M, Wallbrecher R, Cluitmans JC, Verdurmen WP, Tanis S, Adjobo-Hermans MJ, Rademann J, Brock R.

Biochim Biophys Acta. 2014 Dec;1838(12):3097-106. doi: 10.1016/j.bbamem.2014.08.001. Epub 2014 Aug 7.


A quantitative assessment of costimulation and phosphatase activity on microclusters in early T cell signaling.

Witsenburg JJ, Glauner H, Müller JP, Groenewoud JM, Roth G, Böhmer FD, Adjobo-Hermans MJ, Brock R.

PLoS One. 2013 Oct 30;8(10):e79277. doi: 10.1371/journal.pone.0079277. eCollection 2013.


Signaling efficiency of Gαq through its effectors p63RhoGEF and GEFT depends on their subcellular location.

Goedhart J, van Unen J, Adjobo-Hermans MJ, Gadella TW Jr.

Sci Rep. 2013;3:2284. doi: 10.1038/srep02284.


Peptide microarrays to probe for competition for binding sites in a protein interaction network.

Sinzinger MD, Ruttekolk IR, Gloerich J, Wessels H, Chung YD, Adjobo-Hermans MJ, Brock R.

J Proteomics. 2013 Aug 26;89:71-80. doi: 10.1016/j.jprot.2013.05.031. Epub 2013 Jun 5.


Quantitative analysis of self-association and mobility of annexin A4 at the plasma membrane.

Crosby KC, Postma M, Hink MA, Zeelenberg CH, Adjobo-Hermans MJ, Gadella TW.

Biophys J. 2013 May 7;104(9):1875-85. doi: 10.1016/j.bpj.2013.02.057.


PLCβ isoforms differ in their subcellular location and their CT-domain dependent interaction with Gαq.

Adjobo-Hermans MJ, Crosby KC, Putyrski M, Bhageloe A, van Weeren L, Schultz C, Goedhart J, Gadella TW Jr.

Cell Signal. 2013 Jan;25(1):255-63. doi: 10.1016/j.cellsig.2012.09.022. Epub 2012 Sep 21.


Analyzing the homeostasis of signaling proteins by a combination of Western blot and fluorescence correlation spectroscopy.

Chung YD, Sinzinger MD, Bovee-Geurts P, Krause M, Dinkla S, Joosten I, Koopman WJ, Adjobo-Hermans MJ, Brock R.

Biophys J. 2011 Dec 7;101(11):2807-15. doi: 10.1016/j.bpj.2011.09.058.


Quantitative co-expression of proteins at the single cell level--application to a multimeric FRET sensor.

Goedhart J, van Weeren L, Adjobo-Hermans MJ, Elzenaar I, Hink MA, Gadella TW Jr.

PLoS One. 2011;6(11):e27321. doi: 10.1371/journal.pone.0027321. Epub 2011 Nov 17.


Real-time visualization of heterotrimeric G protein Gq activation in living cells.

Adjobo-Hermans MJ, Goedhart J, van Weeren L, Nijmeijer S, Manders EM, Offermanns S, Gadella TW Jr.

BMC Biol. 2011 May 27;9:32. doi: 10.1186/1741-7007-9-32.


Regulation of PLCbeta1a membrane anchoring by its substrate phosphatidylinositol (4,5)-bisphosphate.

Adjobo-Hermans MJ, Goedhart J, Gadella TW Jr.

J Cell Sci. 2008 Nov 15;121(Pt 22):3770-7. doi: 10.1242/jcs.029785. Epub 2008 Oct 28.


Sensitive detection of p65 homodimers using red-shifted and fluorescent protein-based FRET couples.

Goedhart J, Vermeer JE, Adjobo-Hermans MJ, van Weeren L, Gadella TW Jr.

PLoS One. 2007 Oct 10;2(10):e1011.


Plant G protein heterotrimers require dual lipidation motifs of Galpha and Ggamma and do not dissociate upon activation.

Adjobo-Hermans MJ, Goedhart J, Gadella TW Jr.

J Cell Sci. 2006 Dec 15;119(Pt 24):5087-97.


Fluorescence resonance energy transfer (FRET) measurement by gradual acceptor photobleaching.

Van Munster EB, Kremers GJ, Adjobo-Hermans MJ, Gadella TW Jr.

J Microsc. 2005 Jun;218(Pt 3):253-62.

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