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Items: 39


Efficacy of Active Immunization with Attenuated Alpha-Hemolysin and Panton-Valentine Leukocidin in a Rabbit Model of Staphylococcus aureus Necrotizing Pneumonia.

Tran VG, Venkatasubramaniam A, Adhikari RP, Krishnan S, Wang X, Le VTM, Le HN, Vu TTT, Schneider-Smith E, Aman MJ, Diep BA.

J Infect Dis. 2019 Aug 26. pii: jiz437. doi: 10.1093/infdis/jiz437. [Epub ahead of print]


Prevalence of Mental Disorders in Nepal: Findings from the Pilot Study.

Jha AK, Ojha SP, Dahal S, Sharma P, Pant SB, Labh S, Marahatta K, Shakya S, Adhikari RP, Joshi D, Luitel NP, Dhimal M.

J Nepal Health Res Counc. 2019 Aug 4;17(2):141-147. doi: 10.33314/jnhrc.v0i0.1960.


Rational Design of Toxoid Vaccine Candidates for Staphylococcus aureus Leukocidin AB (LukAB).

Kailasan S, Kort T, Mukherjee I, Liao GC, Kanipakala T, Williston N, Ganjbaksh N, Venkatasubramaniam A, Holtsberg FW, Karauzum H, Adhikari RP, Aman MJ.

Toxins (Basel). 2019 Jun 14;11(6). pii: E339. doi: 10.3390/toxins11060339.


Enhancing mental health research capacity: emerging voices from the National Institute of Mental Health (NIMH) global hubs.

da Silva ATC, Hanlon C, Susser E, Rojas G, Claro HG, Quayle J, Habtamu K, Burrone MS, Cavalcanti MT, Sharma M, Schneider M, Adhikari RP, van de Water T, Mohammed Y, Ordóñez AE, Seedat S.

Int J Ment Health Syst. 2019 Apr 3;13:21. doi: 10.1186/s13033-019-0276-9. eCollection 2019.


TBA225, a fusion toxoid vaccine for protection and broad neutralization of staphylococcal superantigens.

Venkatasubramaniam A, Adhikari RP, Kort T, Liao GC, Conley S, Abaandou L, Kailasan S, Onodera Y, Krishnan S, Djagbare DM, Holtsberg FW, Karauzum H, Aman MJ.

Sci Rep. 2019 Mar 1;9(1):3279. doi: 10.1038/s41598-019-39890-z.


Validation of a cross-cultural instrument for child behavior problems: the Disruptive Behavior International Scale - Nepal version.

Burkey MD, Adhikari RP, Ghimire L, Kohrt BA, Wissow LS, Luitel NP, Haroz EE, Jordans MJD.

BMC Psychol. 2018 Nov 3;6(1):51. doi: 10.1186/s40359-018-0262-z.


A Critical Role for HlgA in Staphylococcus aureus Pathogenesis Revealed by A Switch in the SaeRS Two-Component Regulatory System.

Venkatasubramaniam A, Kanipakala T, Ganjbaksh N, Mehr R, Mukherjee I, Krishnan S, Bae T, Aman MJ, Adhikari RP.

Toxins (Basel). 2018 Sep 18;10(9). pii: E377. doi: 10.3390/toxins10090377.


Prevalence of Methicillin Resistant Staphylococcus aureus and Antibiotic Susceptibility Pattern in a Tertiary Hospital in Nepal.

Khanal LK, Adhikari RP, Guragain A.

J Nepal Health Res Counc. 2018 Jul 3;16(2):172-174.


Feasibility study of a family- and school-based intervention for child behavior problems in Nepal.

Adhikari RP, Upadhaya N, Satinsky EN, Burkey MD, Kohrt BA, Jordans MJD.

Child Adolesc Psychiatry Ment Health. 2018 Mar 23;12:20. doi: 10.1186/s13034-018-0226-3. eCollection 2018.


Interpersonal violence and suicidality among former child soldiers and war-exposed civilian children in Nepal.

Bhardwaj A, Bourey C, Rai S, Adhikari RP, Worthman CM, Kohrt BA.

Glob Ment Health (Camb). 2018 Feb 22;5:e9. doi: 10.1017/gmh.2017.31. eCollection 2018.


Psychotropic drugs in Nepal: perceptions on use and supply chain management.

Upadhaya N, Jordans MJD, Gurung D, Pokhrel R, Adhikari RP, Komproe IH.

Global Health. 2018 Jan 24;14(1):10. doi: 10.1186/s12992-018-0322-4.


Inducible clindamycin and methicillin resistant Staphylococcus aureus in a tertiary care hospital, Kathmandu, Nepal.

Adhikari RP, Shrestha S, Barakoti A, Amatya R.

BMC Infect Dis. 2017 Jul 11;17(1):483. doi: 10.1186/s12879-017-2584-5.


Current situations and future directions for mental health system governance in Nepal: findings from a qualitative study.

Upadhaya N, Jordans MJD, Pokhrel R, Gurung D, Adhikari RP, Petersen I, Komproe IH.

Int J Ment Health Syst. 2017 Jun 8;11:37. doi: 10.1186/s13033-017-0145-3. eCollection 2017.


Psychosocial and Mental Health Problems of Older People in Postearthquake Nepal.

Adhikari RP, Upadhaya N, Paudel S, Pokhrel R, Bhandari N, Cole L, Koirala S.

J Aging Health. 2018 Jul;30(6):945-964. doi: 10.1177/0898264317702056. Epub 2017 Apr 3.


Development process of an assessment tool for disruptive behavior problems in cross-cultural settings: the Disruptive Behavior International Scale - Nepal version (DBIS-N).

Burkey MD, Ghimire L, Adhikari RP, Kohrt BA, Jordans MJ, Haroz E, Wissow L.

Int J Cult Ment Health. 2016;9(4):387-398. doi: 10.1080/17542863.2016.1226372. Epub 2016 Sep 14.


Protective efficacy of a novel alpha hemolysin subunit vaccine (AT62) against Staphylococcus aureus skin and soft tissue infections.

Adhikari RP, Thompson CD, Aman MJ, Lee JC.

Vaccine. 2016 Dec 7;34(50):6402-6407. doi: 10.1016/j.vaccine.2016.09.061. Epub 2016 Nov 12.


Safety and Immunogenicity of a Parenterally Administered, Structure-Based Rationally Modified Recombinant Staphylococcal Enterotoxin B Protein Vaccine, STEBVax.

Chen WH, Pasetti MF, Adhikari RP, Baughman H, Douglas R, El-Khorazaty J, Greenberg N, Holtsberg FW, Liao GC, Reymann MK, Wang X, Warfield KL, Aman MJ.

Clin Vaccine Immunol. 2016 Dec 5;23(12):918-925. Print 2016 Dec.


Psychological resilience and the gene regulatory impact of posttraumatic stress in Nepali child soldiers.

Kohrt BA, Worthman CM, Adhikari RP, Luitel NP, Arevalo JM, Ma J, McCreath H, Seeman TE, Crimmins EM, Cole SW.

Proc Natl Acad Sci U S A. 2016 Jul 19;113(29):8156-61. doi: 10.1073/pnas.1601301113. Epub 2016 Jul 11.


The ecocultural context and child behavior problems: A qualitative analysis in rural Nepal.

Burkey MD, Ghimire L, Adhikari RP, Wissow LS, Jordans MJ, Kohrt BA.

Soc Sci Med. 2016 Jun;159:73-82. doi: 10.1016/j.socscimed.2016.04.020. Epub 2016 May 3.


Development of a novel multiplex electrochemiluminescent-based immunoassay for quantification of human serum IgG against 10 Staphylococcus aureus toxins.

Adhikari RP, Haudenschild C, Sterba PM, Sahandi S, Enterlein S, Holtsberg FW, Aman MJ.

J Immunol Methods. 2016 Mar;430:33-42. doi: 10.1016/j.jim.2016.01.013. Epub 2016 Jan 27.


Correction: Antibodies to S. aureus LukS-PV Attenuated Subunit Vaccine Neutralize a Broad Spectrum of Canonical and Non-Canonical Bicomponent Leukotoxin Pairs.

Adhikari RP, Kort T, Shulenin S, Kanipakala T, Ganjbaksh N, Roghmann MC, Holtsberg FW, Aman MJ.

PLoS One. 2015 Nov 16;10(11):e0143493. doi: 10.1371/journal.pone.0143493. eCollection 2015. No abstract available.


Antibodies to S. aureus LukS-PV Attenuated Subunit Vaccine Neutralize a Broad Spectrum of Canonical and Non-Canonical Bicomponent Leukotoxin Pairs.

Adhikari RP, Kort T, Shulenin S, Kanipakala T, Ganjbaksh N, Roghmann MC, Holtsberg FW, Aman MJ.

PLoS One. 2015 Sep 14;10(9):e0137874. doi: 10.1371/journal.pone.0137874. eCollection 2015. Erratum in: PLoS One. 2015;10(11):e0143493.


Perceived behavioral problems of school aged children in rural Nepal: a qualitative study.

Adhikari RP, Upadhaya N, Gurung D, Luitel NP, Burkey MD, Kohrt BA, Jordans MJ.

Child Adolesc Psychiatry Ment Health. 2015 Jun 26;9:25. doi: 10.1186/s13034-015-0061-8. eCollection 2015.


Suicide in South Asia: a scoping review.

Jordans MJ, Kaufman A, Brenman NF, Adhikari RP, Luitel NP, Tol WA, Komproe I.

BMC Psychiatry. 2014 Dec 24;14:358. doi: 10.1186/s12888-014-0358-9. Review.


Staphylococcal bicomponent pore-forming toxins: targets for prophylaxis and immunotherapy.

Aman MJ, Adhikari RP.

Toxins (Basel). 2014 Mar 4;6(3):950-72. doi: 10.3390/toxins6030950. Review.


Structurally designed attenuated subunit vaccines for S. aureus LukS-PV and LukF-PV confer protection in a mouse bacteremia model.

Karauzum H, Adhikari RP, Sarwar J, Devi VS, Abaandou L, Haudenschild C, Mahmoudieh M, Boroun AR, Vu H, Nguyen T, Warfield KL, Shulenin S, Aman MJ.

PLoS One. 2013 Jun 7;8(6):e65384. doi: 10.1371/journal.pone.0065384. Print 2013.


Lower antibody levels to Staphylococcus aureus exotoxins are associated with sepsis in hospitalized adults with invasive S. aureus infections.

Adhikari RP, Ajao AO, Aman MJ, Karauzum H, Sarwar J, Lydecker AD, Johnson JK, Nguyen C, Chen WH, Roghmann MC.

J Infect Dis. 2012 Sep 15;206(6):915-23. doi: 10.1093/infdis/jis462. Epub 2012 Jul 17.


Novel structurally designed vaccine for S. aureus α-hemolysin: protection against bacteremia and pneumonia.

Adhikari RP, Karauzum H, Sarwar J, Abaandou L, Mahmoudieh M, Boroun AR, Vu H, Nguyen T, Devi VS, Shulenin S, Warfield KL, Aman MJ.

PLoS One. 2012;7(6):e38567. doi: 10.1371/journal.pone.0038567. Epub 2012 Jun 6.


Mutations in agr do not persist in natural populations of methicillin-resistant Staphylococcus aureus.

Shopsin B, Eaton C, Wasserman GA, Mathema B, Adhikari RP, Agolory S, Altman DR, Holzman RS, Kreiswirth BN, Novick RP.

J Infect Dis. 2010 Nov 15;202(10):1593-9. doi: 10.1086/656915. Epub 2010 Oct 13.


Prevalence of agr dysfunction among colonizing Staphylococcus aureus strains.

Shopsin B, Drlica-Wagner A, Mathema B, Adhikari RP, Kreiswirth BN, Novick RP.

J Infect Dis. 2008 Oct 15;198(8):1171-4. doi: 10.1086/592051.


Regulatory organization of the staphylococcal sae locus.

Adhikari RP, Novick RP.

Microbiology. 2008 Mar;154(Pt 3):949-59. doi: 10.1099/mic.0.2007/012245-0.


Sequence analysis reveals genetic exchanges and intraspecific spread of SaPI2, a pathogenicity island involved in menstrual toxic shock.

Subedi A, Ubeda C, Adhikari RP, Penadés JR, Novick RP.

Microbiology. 2007 Oct;153(Pt 10):3235-45.


Inhibition of rot translation by RNAIII, a key feature of agr function.

Geisinger E, Adhikari RP, Jin R, Ross HF, Novick RP.

Mol Microbiol. 2006 Aug;61(4):1038-48.


Vancomycin-induced deletion of the methicillin resistance gene mecA in Staphylococcus aureus.

Adhikari RP, Scales GC, Kobayashi K, Smith JM, Berger-Bächi B, Cook GM.

J Antimicrob Chemother. 2004 Aug;54(2):360-3. Epub 2004 Jul 8.


Phenotypic and molecular characterization of community occurring, Western Samoan phage pattern methicillin-resistant Staphylococcus aureus.

Adhikari RP, Cook GM, Lamont I, Lang S, Heffernan H, Smith JM.

J Antimicrob Chemother. 2002 Dec;50(6):825-31.


Antibiotic resistance conferred by conjugative plasmid in Escherichia coli isolated from community ponds of Kathmandu Valley.

Adhikari RP, Kalpana KC, Shears P, Sharma AP.

J Health Popul Nutr. 2000 Jun;18(1):57-9. No abstract available.


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