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Items: 19

1.

Epithelial RNase H2 Maintains Genome Integrity and Prevents Intestinal Tumorigenesis in Mice.

Aden K, Bartsch K, Dahl J, Reijns MAM, Esser D, Sheibani-Tezerji R, Sinha A, Wottawa F, Ito G, Mishra N, Knittler K, Burkholder A, Welz L, van Es J, Tran F, Lipinski S, Kakavand N, Boeger C, Lucius R, von Schoenfels W, Schafmayer C, Lenk L, Chalaris A, Clevers H, Röcken C, Kaleta C, Rose-John S, Schreiber S, Kunkel T, Rabe B, Rosenstiel P.

Gastroenterology. 2018 Sep 28. pii: S0016-5085(18)35077-7. doi: 10.1053/j.gastro.2018.09.047. [Epub ahead of print]

2.

ATG16L1 orchestrates interleukin-22 signaling in the intestinal epithelium via cGAS-STING.

Aden K, Tran F, Ito G, Sheibani-Tezerji R, Lipinski S, Kuiper JW, Tschurtschenthaler M, Saveljeva S, Bhattacharyya J, Häsler R, Bartsch K, Luzius A, Jentzsch M, Falk-Paulsen M, Stengel ST, Welz L, Schwarzer R, Rabe B, Barchet W, Krautwald S, Hartmann G, Pasparakis M, Blumberg RS, Schreiber S, Kaser A, Rosenstiel P.

J Exp Med. 2018 Nov 5;215(11):2868-2886. doi: 10.1084/jem.20171029. Epub 2018 Sep 25.

3.

Vedolizumab is associated with changes in innate rather than adaptive immunity in patients with inflammatory bowel disease.

Zeissig S, Rosati E, Dowds CM, Aden K, Bethge J, Schulte B, Pan WH, Mishra N, Zuhayra M, Marx M, Paulsen M, Strigli A, Conrad C, Schuldt D, Sinha A, Ebsen H, Kornell SC, Nikolaus S, Arlt A, Kabelitz D, Ellrichmann M, Lützen U, Rosenstiel PC, Franke A, Schreiber S.

Gut. 2018 May 5. pii: gutjnl-2018-316023. doi: 10.1136/gutjnl-2018-316023. [Epub ahead of print]

PMID:
29730603
4.

Absence of RNase H2 triggers generation of immunogenic micronuclei removed by autophagy.

Bartsch K, Knittler K, Borowski C, Rudnik S, Damme M, Aden K, Spehlmann ME, Frey N, Saftig P, Chalaris A, Rabe B.

Hum Mol Genet. 2017 Oct 15;26(20):3960-3972. doi: 10.1093/hmg/ddx283.

PMID:
29016854
5.

Increased Tryptophan Metabolism Is Associated With Activity of Inflammatory Bowel Diseases.

Nikolaus S, Schulte B, Al-Massad N, Thieme F, Schulte DM, Bethge J, Rehman A, Tran F, Aden K, Häsler R, Moll N, Schütze G, Schwarz MJ, Waetzig GH, Rosenstiel P, Krawczak M, Szymczak S, Schreiber S.

Gastroenterology. 2017 Dec;153(6):1504-1516.e2. doi: 10.1053/j.gastro.2017.08.028. Epub 2017 Aug 19.

6.

Microbiomarkers in inflammatory bowel diseases: caveats come with caviar.

Sommer F, Rühlemann MC, Bang C, Höppner M, Rehman A, Kaleta C, Schmitt-Kopplin P, Dempfle A, Weidinger S, Ellinghaus E, Krauss-Etschmann S, Schmidt-Arras D, Aden K, Schulte D, Ellinghaus D, Schreiber S, Tholey A, Rupp J, Laudes M, Baines JF, Rosenstiel P, Franke A.

Gut. 2017 Oct;66(10):1734-1738. doi: 10.1136/gutjnl-2016-313678. Epub 2017 Jul 21. No abstract available.

7.

Incidence of Tumour Progression and Pseudoprogression in High-Grade Gliomas: a Systematic Review and Meta-Analysis.

Abbasi AW, Westerlaan HE, Holtman GA, Aden KM, van Laar PJ, van der Hoorn A.

Clin Neuroradiol. 2018 Sep;28(3):401-411. doi: 10.1007/s00062-017-0584-x. Epub 2017 May 2.

8.

The Dark Age(ing) of the Inflammasome.

Aden K, Rosenstiel P.

Immunity. 2017 Feb 21;46(2):173-175. doi: 10.1016/j.immuni.2017.02.009.

9.

Classic IL-6R signalling is dispensable for intestinal epithelial proliferation and repair.

Aden K, Breuer A, Rehman A, Geese H, Tran F, Sommer J, Waetzig GH, Reinheimer TM, Schreiber S, Rose-John S, Scheller J, Rosenstiel P.

Oncogenesis. 2016 Nov 21;5(11):e270. doi: 10.1038/oncsis.2016.71.

10.

Uncoupling of mucosal gene regulation, mRNA splicing and adherent microbiota signatures in inflammatory bowel disease.

Häsler R, Sheibani-Tezerji R, Sinha A, Barann M, Rehman A, Esser D, Aden K, Knecht C, Brandt B, Nikolaus S, Schäuble S, Kaleta C, Franke A, Fretter C, Müller W, Hütt MT, Krawczak M, Schreiber S, Rosenstiel P.

Gut. 2017 Dec;66(12):2087-2097. doi: 10.1136/gutjnl-2016-311651. Epub 2016 Sep 30.

11.

Epithelial IL-23R Signaling Licenses Protective IL-22 Responses in Intestinal Inflammation.

Aden K, Rehman A, Falk-Paulsen M, Secher T, Kuiper J, Tran F, Pfeuffer S, Sheibani-Tezerji R, Breuer A, Luzius A, Jentzsch M, Häsler R, Billmann-Born S, Will O, Lipinski S, Bharti R, Adolph T, Iovanna JL, Kempster SL, Blumberg RS, Schreiber S, Becher B, Chamaillard M, Kaser A, Rosenstiel P.

Cell Rep. 2016 Aug 23;16(8):2208-2218. doi: 10.1016/j.celrep.2016.07.054. Epub 2016 Aug 11.

12.

Modulation of nuclear factor E2-related factor-2 (Nrf2) activation by the stress response gene immediate early response-3 (IER3) in colonic epithelial cells: a novel mechanism of cellular adaption to inflammatory stress.

Stachel I, Geismann C, Aden K, Deisinger F, Rosenstiel P, Schreiber S, Sebens S, Arlt A, Schäfer H.

J Biol Chem. 2014 Jan 24;289(4):1917-29. doi: 10.1074/jbc.M113.490920. Epub 2013 Dec 5.

13.

RNAi screening identifies mediators of NOD2 signaling: implications for spatial specificity of MDP recognition.

Lipinski S, Grabe N, Jacobs G, Billmann-Born S, Till A, Häsler R, Aden K, Paulsen M, Arlt A, Kraemer L, Hagemann N, Erdmann KS, Schreiber S, Rosenstiel P.

Proc Natl Acad Sci U S A. 2012 Dec 26;109(52):21426-31. doi: 10.1073/pnas.1209673109. Epub 2012 Dec 3.

14.

Extracellular cathepsin K exerts antimicrobial activity and is protective against chronic intestinal inflammation in mice.

Sina C, Lipinski S, Gavrilova O, Aden K, Rehman A, Till A, Rittger A, Podschun R, Meyer-Hoffert U, Haesler R, Midtling E, Pütsep K, McGuckin MA, Schreiber S, Saftig P, Rosenstiel P.

Gut. 2013 Apr;62(4):520-30. doi: 10.1136/gutjnl-2011-300076. Epub 2012 Mar 22.

PMID:
22442160
15.

Toll-like receptor-7 ligand Imiquimod induces type I interferon and antimicrobial peptides to ameliorate dextran sodium sulfate-induced acute colitis.

Sainathan SK, Bishnupuri KS, Aden K, Luo Q, Houchen CW, Anant S, Dieckgraefe BK.

Inflamm Bowel Dis. 2012 May;18(5):955-67. doi: 10.1002/ibd.21867. Epub 2011 Sep 26.

16.

Reg IV regulates normal intestinal and colorectal cancer cell susceptibility to radiation-induced apoptosis.

Bishnupuri KS, Luo Q, Sainathan SK, Kikuchi K, Sureban SM, Sabarinathan M, Gross JH, Aden K, May R, Houchen CW, Anant S, Dieckgraefe BK.

Gastroenterology. 2010 Feb;138(2):616-26, 626.e1-2. doi: 10.1053/j.gastro.2009.10.050. Epub 2009 Nov 10.

17.

The evaluation of pharmacologic agents on composite graft survival.

Aden KK, Biel MA.

Arch Otolaryngol Head Neck Surg. 1992 Feb;118(2):175-8.

PMID:
1540349
18.

Ludwig's angina.

Aden K, Nissen RL, Spaur C, Yonkers AJ.

Ear Nose Throat J. 1985 Apr;64(4):168-72. No abstract available.

PMID:
3996263
19.

Ludwig's angina.

Aden KK, Nissen RL, Spaur C, Yonkers AJ.

Nebr Med J. 1984 Dec;69(12):395-8. No abstract available.

PMID:
6521779

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