Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 205


Investigation of the molecular biology underlying the pronounced high gene targeting frequency at the Myh9 gene locus in mouse embryonic stem cells.

Tan L, Hu Y, Li Y, Yang L, Cai X, Liu W, He J, Wu Y, Liu T, Wang N, Yang Y, Adelstein RS, Wang A.

PLoS One. 2020 Mar 30;15(3):e0230126. doi: 10.1371/journal.pone.0230126. eCollection 2020.


The role of nonmuscle myosin 2A and 2B in the regulation of mesenchymal cell contact guidance.

Zhovmer AS, Tabdanov ED, Miao H, Wen H, Chen J, Luo X, Ma X, Provenzano PP, Adelstein RS.

Mol Biol Cell. 2019 Jul 22;30(16):1961-1973. doi: 10.1091/mbc.E19-01-0071. Epub 2019 Jul 18.


Mesenchymal actomyosin contractility is required for androgen-driven urethral masculinization in mice.

Acebedo AR, Suzuki K, Hino S, Alcantara MC, Sato Y, Haga H, Matsumoto KI, Nakao M, Shimamura K, Takeo T, Nakagata N, Miyagawa S, Nishinakamura R, Adelstein RS, Yamada G.

Commun Biol. 2019 Mar 8;2:95. doi: 10.1038/s42003-019-0336-3. eCollection 2019.


Myh10 deficiency leads to defective extracellular matrix remodeling and pulmonary disease.

Kim HT, Yin W, Jin YJ, Panza P, Gunawan F, Grohmann B, Buettner C, Sokol AM, Preussner J, Guenther S, Kostin S, Ruppert C, Bhagwat AM, Ma X, Graumann J, Looso M, Guenther A, Adelstein RS, Offermanns S, Stainier DYR.

Nat Commun. 2018 Nov 2;9(1):4600. doi: 10.1038/s41467-018-06833-7.


Replacing nonmuscle myosin 2A with myosin 2C1 permits gastrulation but not placenta vascular development in mice.

Zhang Y, Liu C, Adelstein RS, Ma X.

Mol Biol Cell. 2018 Sep 15;29(19):2326-2335. doi: 10.1091/mbc.E17-12-0713. Epub 2018 Jul 25.


MYH9: Structure, functions and role of non-muscle myosin IIA in human disease.

Pecci A, Ma X, Savoia A, Adelstein RS.

Gene. 2018 Jul 20;664:152-167. doi: 10.1016/j.gene.2018.04.048. Epub 2018 Apr 19. Review.


Parallel assembly of actin and tropomyosin, but not myosin II, during de novo actin filament formation in live mice.

Masedunskas A, Appaduray MA, Lucas CA, Lastra Cagigas M, Heydecker M, Holliday M, Meiring JCM, Hook J, Kee A, White M, Thomas P, Zhang Y, Adelstein RS, Meckel T, Böcking T, Weigert R, Bryce NS, Gunning PW, Hardeman EC.

J Cell Sci. 2018 Mar 19;131(6). pii: jcs212654. doi: 10.1242/jcs.212654.


Identification and characterization of MYH9 locus for high efficient gene knock-in and stable expression in mouse embryonic stem cells.

Liu T, Hu Y, Guo S, Tan L, Zhan Y, Yang L, Liu W, Wang N, Li Y, Zhang Y, Liu C, Yang Y, Adelstein RS, Wang A.

PLoS One. 2018 Feb 13;13(2):e0192641. doi: 10.1371/journal.pone.0192641. eCollection 2018.


Stress Granules Contain Rbfox2 with Cell Cycle-related mRNAs.

Park C, Choi S, Kim YE, Lee S, Park SH, Adelstein RS, Kawamoto S, Kim KK.

Sci Rep. 2017 Sep 11;7(1):11211. doi: 10.1038/s41598-017-11651-w.


Nonmuscle myosin IIB regulates epicardial integrity and epicardium-derived mesenchymal cell maturation.

Ma X, Sung DC, Yang Y, Wakabayashi Y, Adelstein RS.

J Cell Sci. 2017 Aug 15;130(16):2696-2706. doi: 10.1242/jcs.202564. Epub 2017 Jul 7.


Concerted actions of distinct nonmuscle myosin II isoforms drive intracellular membrane remodeling in live animals.

Milberg O, Shitara A, Ebrahim S, Masedunskas A, Tora M, Tran DT, Chen Y, Conti MA, Adelstein RS, Ten Hagen KG, Weigert R.

J Cell Biol. 2017 Jul 3;216(7):1925-1936. doi: 10.1083/jcb.201612126. Epub 2017 Jun 9.


Non-muscle myosin II deletion in the developing kidney causes ureter-bladder misconnection and apical extrusion of the nephric duct lineage epithelia.

Haque F, Kaku Y, Fujimura S, Ohmori T, Adelstein RS, Nishinakamura R.

Dev Biol. 2017 Jul 1;427(1):121-130. doi: 10.1016/j.ydbio.2017.04.020. Epub 2017 May 3.


Actin dynamics and competition for myosin monomer govern the sequential amplification of myosin filaments.

Beach JR, Bruun KS, Shao L, Li D, Swider Z, Remmert K, Zhang Y, Conti MA, Adelstein RS, Rusan NM, Betzig E, Hammer JA.

Nat Cell Biol. 2017 Feb;19(2):85-93. doi: 10.1038/ncb3463. Epub 2017 Jan 23.


Local pulsatile contractions are an intrinsic property of the myosin 2A motor in the cortical cytoskeleton of adherent cells.

Baird MA, Billington N, Wang A, Adelstein RS, Sellers JR, Fischer RS, Waterman CM.

Mol Biol Cell. 2017 Jan 15;28(2):240-251. doi: 10.1091/mbc.E16-05-0335. Epub 2016 Nov 23.


Nonmuscle Myosin IIA Regulates Intestinal Epithelial Barrier in vivo and Plays a Protective Role During Experimental Colitis.

Naydenov NG, Feygin A, Wang D, Kuemmerle JF, Harris G, Conti MA, Adelstein RS, Ivanov AI.

Sci Rep. 2016 Apr 11;6:24161. doi: 10.1038/srep24161.


Limb body wall complex, amniotic band sequence, or new syndrome caused by mutation in IQ Motif containing K (IQCK)?

Kruszka P, Uwineza A, Mutesa L, Martinez AF, Abe Y, Zackai EH, Ganetzky R, Chung B, Stevenson RE, Adelstein RS, Ma X, Mullikin JC, Hong SK, Muenke M.

Mol Genet Genomic Med. 2015 Sep;3(5):424-32. doi: 10.1002/mgg3.153. Epub 2015 May 6.


Conditional deletion of nonmuscle myosin II-A in mouse tongue epithelium results in squamous cell carcinoma.

Conti MA, Saleh AD, Brinster LR, Cheng H, Chen Z, Cornelius S, Liu C, Ma X, Van Waes C, Adelstein RS.

Sci Rep. 2015 Sep 15;5:14068. doi: 10.1038/srep14068.


Corrigendum: Cell migration and antigen capture are antagonistic processes coupled by myosin II in dendritic cells.

Chabaud M, Heuzé ML, Bretou M, Vargas P, Maiuri P, Solanes P, Maurin M, Terriac E, Le Berre M, Lankar D, Piolot T, Adelstein RS, Zhang Y, Sixt M, Jacobelli J, Bénichou O, Voituriez R, Piel M, Lennon-Duménil AM.

Nat Commun. 2015 Aug 14;6:8122. doi: 10.1038/ncomms9122. No abstract available.


PKC412 normalizes mutation-related keratin filament disruption and hepatic injury in mice by promoting keratin-myosin binding.

Kwan R, Chen L, Looi K, Tao GZ, Weerasinghe SV, Snider NT, Conti MA, Adelstein RS, Xie Q, Omary MB.

Hepatology. 2015 Dec;62(6):1858-69. doi: 10.1002/hep.27965. Epub 2015 Aug 25.


Cell migration and antigen capture are antagonistic processes coupled by myosin II in dendritic cells.

Chabaud M, Heuzé ML, Bretou M, Vargas P, Maiuri P, Solanes P, Maurin M, Terriac E, Le Berre M, Lankar D, Piolot T, Adelstein RS, Zhang Y, Sixt M, Jacobelli J, Bénichou O, Voituriez R, Piel M, Lennon-Duménil AM.

Nat Commun. 2015 Jun 25;6:7526. doi: 10.1038/ncomms8526. Erratum in: Nat Commun. 2015;6:8122.


Convergence and extrusion are required for normal fusion of the mammalian secondary palate.

Kim S, Lewis AE, Singh V, Ma X, Adelstein R, Bush JO.

PLoS Biol. 2015 Apr 7;13(4):e1002122. doi: 10.1371/journal.pbio.1002122. eCollection 2015 Apr.


Myosin II controls cellular branching morphogenesis and migration in three dimensions by minimizing cell-surface curvature.

Elliott H, Fischer RS, Myers KA, Desai RA, Gao L, Chen CS, Adelstein RS, Waterman CM, Danuser G.

Nat Cell Biol. 2015 Feb;17(2):137-47. doi: 10.1038/ncb3092. Epub 2015 Jan 26.


Rbfox3 controls the biogenesis of a subset of microRNAs.

Kim KK, Yang Y, Zhu J, Adelstein RS, Kawamoto S.

Nat Struct Mol Biol. 2014 Oct;21(10):901-10. doi: 10.1038/nsmb.2892. Epub 2014 Sep 21.


Nonmuscle Myosin II Regulates the Morphogenesis of Metanephric Mesenchyme-Derived Immature Nephrons.

Recuenco MC, Ohmori T, Tanigawa S, Taguchi A, Fujimura S, Conti MA, Wei Q, Kiyonari H, Abe T, Adelstein RS, Nishinakamura R.

J Am Soc Nephrol. 2015 May;26(5):1081-91. doi: 10.1681/ASN.2014030281. Epub 2014 Aug 28.


The role of vertebrate nonmuscle Myosin II in development and human disease.

Ma X, Adelstein RS.

Bioarchitecture. 2014;4(3):88-102. doi: 10.4161/bioa.29766. Epub 2014 Aug 6. Review.


Isoform-specific proteasomal degradation of Rbfox3 during chicken embryonic development.

Kim KK, Adelstein RS, Kawamoto S.

Biochem Biophys Res Commun. 2014 Aug 8;450(4):1662-7. doi: 10.1016/j.bbrc.2014.07.057. Epub 2014 Jul 17.


Folliculin (Flcn) inactivation leads to murine cardiac hypertrophy through mTORC1 deregulation.

Hasumi Y, Baba M, Hasumi H, Huang Y, Lang M, Reindorf R, Oh HB, Sciarretta S, Nagashima K, Haines DC, Schneider MD, Adelstein RS, Schmidt LS, Sadoshima J, Marston Linehan W.

Hum Mol Genet. 2014 Nov 1;23(21):5706-19. doi: 10.1093/hmg/ddu286. Epub 2014 Jun 6.


A point mutation in Myh10 causes major defects in heart development and body wall closure.

Ma X, Adelstein RS.

Circ Cardiovasc Genet. 2014 Jun;7(3):257-65. doi: 10.1161/CIRCGENETICS.113.000455. Epub 2014 May 13. Erratum in: Circ Cardiovasc Genet. 2014 Aug;7(4):570.


Nonmuscle myosin II is a critical regulator of clathrin-mediated endocytosis.

Chandrasekar I, Goeckeler ZM, Turney SG, Wang P, Wysolmerski RB, Adelstein RS, Bridgman PC.

Traffic. 2014 Apr;15(4):418-32. doi: 10.1111/tra.12152. Epub 2014 Feb 12.


N-cadherin sustains motility and polarity of future cortical interneurons during tangential migration.

Luccardini C, Hennekinne L, Viou L, Yanagida M, Murakami F, Kessaris N, Ma X, Adelstein RS, Mège RM, Métin C.

J Neurosci. 2013 Nov 13;33(46):18149-60. doi: 10.1523/JNEUROSCI.0593-13.2013.


Characterization of three full-length human nonmuscle myosin II paralogs.

Billington N, Wang A, Mao J, Adelstein RS, Sellers JR.

J Biol Chem. 2013 Nov 15;288(46):33398-410. doi: 10.1074/jbc.M113.499848. Epub 2013 Sep 26.


Keratin 5-Cre-driven excision of nonmuscle myosin IIA in early embryo trophectoderm leads to placenta defects and embryonic lethality.

Crish J, Conti MA, Sakai T, Adelstein RS, Egelhoff TT.

Dev Biol. 2013 Oct 1;382(1):136-48. doi: 10.1016/j.ydbio.2013.07.017. Epub 2013 Jul 30.


NMII forms a contractile transcellular sarcomeric network to regulate apical cell junctions and tissue geometry.

Ebrahim S, Fujita T, Millis BA, Kozin E, Ma X, Kawamoto S, Baird MA, Davidson M, Yonemura S, Hisa Y, Conti MA, Adelstein RS, Sakaguchi H, Kachar B.

Curr Biol. 2013 Apr 22;23(8):731-6. doi: 10.1016/j.cub.2013.03.039. Epub 2013 Apr 4.


Nonmuscle myosin IIB links cytoskeleton to IRE1α signaling during ER stress.

He Y, Beatty A, Han X, Ji Y, Ma X, Adelstein RS, Yates JR 3rd, Kemphues K, Qi L.

Dev Cell. 2012 Dec 11;23(6):1141-52. doi: 10.1016/j.devcel.2012.11.006.


Non-muscle myosin IIB is essential for cytokinesis during male meiotic cell divisions.

Yang F, Wei Q, Adelstein RS, Wang PJ.

Dev Biol. 2012 Sep 15;369(2):356-61. doi: 10.1016/j.ydbio.2012.07.011. Epub 2012 Jul 20.


Nonmuscle myosin II is required for internalization of the epidermal growth factor receptor and modulation of downstream signaling.

Kim JH, Wang A, Conti MA, Adelstein RS.

J Biol Chem. 2012 Aug 10;287(33):27345-58. doi: 10.1074/jbc.M111.304824. Epub 2012 Jun 20.


Nonmuscle myosin II exerts tension but does not translocate actin in vertebrate cytokinesis.

Ma X, Kovács M, Conti MA, Wang A, Zhang Y, Sellers JR, Adelstein RS.

Proc Natl Acad Sci U S A. 2012 Mar 20;109(12):4509-14. doi: 10.1073/pnas.1116268109. Epub 2012 Mar 5.


Micro-environmental control of cell migration--myosin IIA is required for efficient migration in fibrillar environments through control of cell adhesion dynamics.

Doyle AD, Kutys ML, Conti MA, Matsumoto K, Adelstein RS, Yamada KM.

J Cell Sci. 2012 May 1;125(Pt 9):2244-56. doi: 10.1242/jcs.098806. Epub 2012 Feb 10.


In vivo studies on nonmuscle myosin II expression and function in heart development.

Ma X, Adelstein RS.

Front Biosci (Landmark Ed). 2012 Jan 1;17:545-55. Review.


Distinct and redundant roles of the non-muscle myosin II isoforms and functional domains.

Wang A, Ma X, Conti MA, Adelstein RS.

Biochem Soc Trans. 2011 Oct;39(5):1131-5. doi: 10.1042/BST0391131. Review.


Mouse models of MYH9-related disease: mutations in nonmuscle myosin II-A.

Zhang Y, Conti MA, Malide D, Dong F, Wang A, Shmist YA, Liu C, Zerfas P, Daniels MP, Chan CC, Kozin E, Kachar B, Kelley MJ, Kopp JB, Adelstein RS.

Blood. 2012 Jan 5;119(1):238-50. doi: 10.1182/blood-2011-06-358853. Epub 2011 Sep 8.


Actin and myosin contribute to mammalian mitochondrial DNA maintenance.

Reyes A, He J, Mao CC, Bailey LJ, Di Re M, Sembongi H, Kazak L, Dzionek K, Holmes JB, Cluett TJ, Harbour ME, Fearnley IM, Crouch RJ, Conti MA, Adelstein RS, Walker JE, Holt IJ.

Nucleic Acids Res. 2011 Jul;39(12):5098-108. doi: 10.1093/nar/gkr052. Epub 2011 Mar 11.


LPA(1) -induced migration requires nonmuscle myosin II light chain phosphorylation in breast cancer cells.

Kim JH, Adelstein RS.

J Cell Physiol. 2011 Nov;226(11):2881-93. doi: 10.1002/jcp.22631.


Fox-3 and PSF interact to activate neural cell-specific alternative splicing.

Kim KK, Kim YC, Adelstein RS, Kawamoto S.

Nucleic Acids Res. 2011 Apr;39(8):3064-78. doi: 10.1093/nar/gkq1221. Epub 2010 Dec 21.


Ablation of nonmuscle myosin II-B and II-C reveals a role for nonmuscle myosin II in cardiac myocyte karyokinesis.

Ma X, Jana SS, Conti MA, Kawamoto S, Claycomb WC, Adelstein RS.

Mol Biol Cell. 2010 Nov 15;21(22):3952-62. doi: 10.1091/mbc.E10-04-0293. Epub 2010 Sep 22.


Non-muscle myosin II regulates survival threshold of pluripotent stem cells.

Walker A, Su H, Conti MA, Harb N, Adelstein RS, Sato N.

Nat Commun. 2010 Sep 7;1:71. doi: 10.1038/ncomms1074.


Confinement-optimized three-dimensional T cell amoeboid motility is modulated via myosin IIA-regulated adhesions.

Jacobelli J, Friedman RS, Conti MA, Lennon-Dumenil AM, Piel M, Sorensen CM, Adelstein RS, Krummel MF.

Nat Immunol. 2010 Oct;11(10):953-61. doi: 10.1038/ni.1936. Epub 2010 Sep 12.


Nonmuscle myosin II isoform and domain specificity during early mouse development.

Wang A, Ma X, Conti MA, Liu C, Kawamoto S, Adelstein RS.

Proc Natl Acad Sci U S A. 2010 Aug 17;107(33):14645-50. doi: 10.1073/pnas.1004023107. Epub 2010 Aug 2.


Myosin II isoforms identify distinct functional modules that support integrity of the epithelial zonula adherens.

Smutny M, Cox HL, Leerberg JM, Kovacs EM, Conti MA, Ferguson C, Hamilton NA, Parton RG, Adelstein RS, Yap AS.

Nat Cell Biol. 2010 Jul;12(7):696-702. doi: 10.1038/ncb2072. Epub 2010 Jun 13.


Non-muscle myosin II takes centre stage in cell adhesion and migration.

Vicente-Manzanares M, Ma X, Adelstein RS, Horwitz AR.

Nat Rev Mol Cell Biol. 2009 Nov;10(11):778-90. doi: 10.1038/nrm2786. Review.

Supplemental Content

Loading ...
Support Center