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Items: 6


NKTR-214, an Engineered Cytokine with Biased IL2 Receptor Binding, Increased Tumor Exposure, and Marked Efficacy in Mouse Tumor Models.

Charych DH, Hoch U, Langowski JL, Lee SR, Addepalli MK, Kirk PB, Sheng D, Liu X, Sims PW, VanderVeen LA, Ali CF, Chang TK, Konakova M, Pena RL, Kanhere RS, Kirksey YM, Ji C, Wang Y, Huang J, Sweeney TD, Kantak SS, Doberstein SK.

Clin Cancer Res. 2016 Feb 1;22(3):680-90. doi: 10.1158/1078-0432.CCR-15-1631.


VEGF-C differentially regulates VEGF-A expression in ocular and cancer cells; promotes angiogenesis via RhoA mediated pathway.

Kumar B, Chile SA, Ray KB, Reddy GE, Addepalli MK, Kumar AS, Ramana V, Rajagopal V.

Angiogenesis. 2011 Sep;14(3):371-80. doi: 10.1007/s10456-011-9221-5. Epub 2011 Jun 23.


RNAi-mediated knockdown of AURKB and EGFR shows enhanced therapeutic efficacy in prostate tumor regression.

Addepalli MK, Ray KB, Kumar B, Ramnath RL, Chile S, Rao H.

Gene Ther. 2010 Mar;17(3):352-9. doi: 10.1038/gt.2009.155. Epub 2009 Dec 3.


Suppressors of zyg-1 define regulators of centrosome duplication and nuclear association in Caenorhabditis elegans.

Kemp CA, Song MH, Addepalli MK, Hunter G, O'Connell K.

Genetics. 2007 May;176(1):95-113. Epub 2007 Apr 19.


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