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Items: 1 to 50 of 812

1.

Diverse Chemical Scaffolds Enhance Oligodendrocyte Formation by Inhibiting CYP51, TM7SF2, or EBP.

Allimuthu D, Hubler Z, Najm FJ, Tang H, Bederman I, Seibel W, Tesar PJ, Adams DJ.

Cell Chem Biol. 2019 Jan 31. pii: S2451-9456(19)30026-1. doi: 10.1016/j.chembiol.2019.01.004. [Epub ahead of print]

PMID:
30773481
2.

Correction to "Supramolecular Nucleoside-Based Gel: Molecular Dynamics Simulation and Characterization of Its Nanoarchitecture and Self-Assembly Mechanism".

Angelerou MGF, Frederix PWJM, Wallace M, Yang B, Rodger A, Adams DJ, Marlow M, Zelzer M.

Langmuir. 2019 Feb 19;35(7):2885. doi: 10.1021/acs.langmuir.9b00009. Epub 2019 Feb 7. No abstract available.

PMID:
30730748
3.

Annealing multicomponent supramolecular gels.

Fuentes-Caparrós AM, de Paula Gómez-Franco F, Dietrich B, Wilson C, Brasnett C, Seddon A, Adams DJ.

Nanoscale. 2019 Feb 14;11(7):3275-3280. doi: 10.1039/c8nr09423c.

PMID:
30720823
4.

Probing the self-assembled structures and pKa of hydrogels using electrochemical methods.

Cross ER, Adams DJ.

Soft Matter. 2019 Feb 13;15(7):1522-1528. doi: 10.1039/c8sm02430h.

PMID:
30681698
5.

Does Drying Affect Gel Networks?

Adams DJ.

Gels. 2018 Apr 3;4(2). pii: E32. doi: 10.3390/gels4020032.

6.

Using Aggregation-Induced Emission to Understand Dipeptide Gels.

Castilla AM, Dietrich B, Adams DJ.

Gels. 2018 Feb 9;4(1). pii: E17. doi: 10.3390/gels4010017.

7.

Cross-species genomic landscape comparison of human mucosal melanoma with canine oral and equine melanoma.

Wong K, van der Weyden L, Schott CR, Foote A, Constantino-Casas F, Smith S, Dobson JM, Murchison EP, Wu H, Yeh I, Fullen DR, Joseph N, Bastian BC, Patel RM, Martincorena I, Robles-Espinoza CD, Iyer V, Kuijjer ML, Arends MJ, Brenn T, Harms PW, Wood GA, Adams DJ.

Nat Commun. 2019 Jan 21;10(1):353. doi: 10.1038/s41467-018-08081-1.

8.

A miRNA-Mediated Approach to Dissect the Complexity of Tumor-Initiating Cell Function and Identify miRNA-Targeting Drugs.

Belur Nagaraj A, Joseph P, Ponting E, Fedorov Y, Singh S, Cole A, Lee W, Yoon E, Baccarini A, Scacheri P, Buckanovich R, Adams DJ, Drapkin R, Brown BD, DiFeo A.

Stem Cell Reports. 2019 Jan 8;12(1):122-134. doi: 10.1016/j.stemcr.2018.12.002.

9.

Chemical control of structure and guest uptake by a conformationally mobile porous material.

Katsoulidis AP, Antypov D, Whitehead GFS, Carrington EJ, Adams DJ, Berry NG, Darling GR, Dyer MS, Rosseinsky MJ.

Nature. 2019 Jan;565(7738):213-217. doi: 10.1038/s41586-018-0820-9. Epub 2019 Jan 9.

PMID:
30626943
10.

ATM orchestrates the DNA-damage response to counter toxic non-homologous end-joining at broken replication forks.

Balmus G, Pilger D, Coates J, Demir M, Sczaniecka-Clift M, Barros AC, Woods M, Fu B, Yang F, Chen E, Ostermaier M, Stankovic T, Ponstingl H, Herzog M, Yusa K, Martinez FM, Durant ST, Galanty Y, Beli P, Adams DJ, Bradley A, Metzakopian E, Forment JV, Jackson SP.

Nat Commun. 2019 Jan 8;10(1):87. doi: 10.1038/s41467-018-07729-2.

11.

An atlas of genetic influences on osteoporosis in humans and mice.

Morris JA, Kemp JP, Youlten SE, Laurent L, Logan JG, Chai RC, Vulpescu NA, Forgetta V, Kleinman A, Mohanty ST, Sergio CM, Quinn J, Nguyen-Yamamoto L, Luco AL, Vijay J, Simon MM, Pramatarova A, Medina-Gomez C, Trajanoska K, Ghirardello EJ, Butterfield NC, Curry KF, Leitch VD, Sparkes PC, Adoum AT, Mannan NS, Komla-Ebri DSK, Pollard AS, Dewhurst HF, Hassall TAD, Beltejar MG; 23andMe Research Team, Adams DJ, Vaillancourt SM, Kaptoge S, Baldock P, Cooper C, Reeve J, Ntzani EE, Evangelou E, Ohlsson C, Karasik D, Rivadeneira F, Kiel DP, Tobias JH, Gregson CL, Harvey NC, Grundberg E, Goltzman D, Adams DJ, Lelliott CJ, Hinds DA, Ackert-Bicknell CL, Hsu YH, Maurano MT, Croucher PI, Williams GR, Bassett JHD, Evans DM, Richards JB.

Nat Genet. 2019 Feb;51(2):258-266. doi: 10.1038/s41588-018-0302-x. Epub 2018 Dec 31.

PMID:
30598549
12.

Association of the POT1 Germline Missense Variant p.I78T With Familial Melanoma.

Wong K, Robles-Espinoza CD, Rodriguez D, Rudat SS, Puig S, Potrony M, Wong CC, Hewinson J, Aguilera P, Puig-Butille JA, Bressac-de Paillerets B, Zattara H, van der Weyden L, Fletcher CDM, Brenn T, Arends MJ, Quesada V, Newton-Bishop JA, Lopez-Otin C, Bishop DT, Harms PW, Johnson TM, Durham AB, Lombard DB, Adams DJ.

JAMA Dermatol. 2018 Dec 26. doi: 10.1001/jamadermatol.2018.3662. [Epub ahead of print]

PMID:
30586141
13.

Visualising the Cardiovascular System of Embryos of Biomedical Model Organisms with High Resolution Episcopic Microscopy (HREM).

Weninger WJ, Maurer-Gesek B, Reissig LF, Prin F, Wilson R, Galli A, Adams DJ, White JK, Mohun TJ, Geyer SH.

J Cardiovasc Dev Dis. 2018 Dec 15;5(4). pii: E58. doi: 10.3390/jcdd5040058. Review.

14.

Maintaining homogeneity during a sol-gel transition by an autocatalytic enzyme reaction.

Panja S, Adams DJ.

Chem Commun (Camb). 2018 Dec 18;55(1):47-50. doi: 10.1039/c8cc08501c.

PMID:
30507994
15.

Comprehensive Study of the Clinical Phenotype of Germline BAP1 Variant-Carrying Families Worldwide.

Walpole S, Pritchard AL, Cebulla CM, Pilarski R, Stautberg M, Davidorf FH, de la Fouchardière A, Cabaret O, Golmard L, Stoppa-Lyonnet D, Garfield E, Njauw CN, Cheung M, Turunen JA, Repo P, Järvinen RS, van Doorn R, Jager MJ, Luyten GPM, Marinkovic M, Chau C, Potrony M, Höiom V, Helgadottir H, Pastorino L, Bruno W, Andreotti V, Dalmasso B, Ciccarese G, Queirolo P, Mastracci L, Wadt K, Kiilgaard JF, Speicher MR, van Poppelen N, Kilic E, Al-Jamal RT, Dianzani I, Betti M, Bergmann C, Santagata S, Dahiya S, Taibjee S, Burke J, Poplawski N, O'Shea SJ, Newton-Bishop J, Adlard J, Adams DJ, Lane AM, Kim I, Klebe S, Racher H, Harbour JW, Nickerson ML, Murali R, Palmer JM, Howlie M, Symmons J, Hamilton H, Warrier S, Glasson W, Johansson P, Robles-Espinoza CD, Ossio R, de Klein A, Puig S, Ghiorzo P, Nielsen M, Kivelä TT, Tsao H, Testa JR, Gerami P, Stern MH, Paillerets BB, Abdel-Rahman MH, Hayward NK.

J Natl Cancer Inst. 2018 Dec 1;110(12):1328-1341. doi: 10.1093/jnci/djy171.

PMID:
30517737
16.

Melanoma subtypes: genomic profiles, prognostic molecular markers and therapeutic possibilities.

Rabbie R, Ferguson P, Molina-Aguilar C, Adams DJ, Robles-Espinoza CD.

J Pathol. 2018 Dec 3. doi: 10.1002/path.5213. [Epub ahead of print] Review.

PMID:
30511391
17.

Non-invasive imaging reveals conditions that impact distribution and persistence of cells after in vivo administration.

Scarfe L, Taylor A, Sharkey J, Harwood R, Barrow M, Comenge J, Beeken L, Astley C, Santeramo I, Hutchinson C, Ressel L, Smythe J, Austin E, Levy R, Rosseinsky MJ, Adams DJ, Poptani H, Park BK, Murray P, Wilm B.

Stem Cell Res Ther. 2018 Nov 28;9(1):332. doi: 10.1186/s13287-018-1076-x.

18.

Investigating the breakdown of the nerve agent simulant methyl paraoxon and chemical warfare agents GB and VX using nitrogen containing bases.

Wilson C, Cooper NJ, Briggs ME, Cooper AI, Adams DJ.

Org Biomol Chem. 2018 Dec 5;16(47):9285-9291. doi: 10.1039/c8ob02475h.

PMID:
30480295
19.

POT1 germline mutations but not TERT promoter mutations are implicated in melanoma susceptibility in a large cohort of Spanish melanoma families.

Potrony M, Puig-Butille JA, Ribera-Sola M, Iyer V, Robles-Espinoza CD, Aguilera P, Carrera C, Malvehy J, Badenas C, Landi MT, Adams DJ, Puig S.

Br J Dermatol. 2018 Nov 19. doi: 10.1111/bjd.17443. [Epub ahead of print]

PMID:
30451293
20.

IFITM proteins drive type 2 T helper cell differentiation and exacerbate allergic airway inflammation.

Yánez DC, Sahni H, Ross S, Solanki A, Lau CI, Papaioannou E, Barbarulo A, Powell R, Lange UC, Adams DJ, Barenco M, Ono M, D'Acquisto F, Furmanski AL, Crompton T.

Eur J Immunol. 2019 Jan;49(1):66-78. doi: 10.1002/eji.201847692. Epub 2018 Nov 9.

PMID:
30365177
21.

NMR Structure of μ-Conotoxin GIIIC: Leucine 18 Induces Local Repacking of the N-Terminus Resulting in Reduced NaV Channel Potency.

Harvey PJ, Kurniawan ND, Finol-Urdaneta RK, McArthur JR, Van Lysebetten D, Dash TS, Hill JM, Adams DJ, Durek T, Craik DJ.

Molecules. 2018 Oct 22;23(10). pii: E2715. doi: 10.3390/molecules23102715.

22.

Targeting of N-Type Calcium Channels via GABAB-Receptor Activation by α-Conotoxin Vc1.1 Variants Displaying Improved Analgesic Activity.

Cai F, Xu N, Liu Z, Ding R, Yu S, Dong M, Wang S, Shen J, Tae HS, Adams DJ, Zhang X, Dai Q.

J Med Chem. 2018 Nov 21;61(22):10198-10205. doi: 10.1021/acs.jmedchem.8b01343. Epub 2018 Nov 6.

PMID:
30358401
23.

ALDH1 Bio-activates Nifuroxazide to Eradicate ALDHHigh Melanoma-Initiating Cells.

Sarvi S, Crispin R, Lu Y, Zeng L, Hurley TD, Houston DR, von Kriegsheim A, Chen CH, Mochly-Rosen D, Ranzani M, Mathers ME, Xu X, Xu W, Adams DJ, Carragher NO, Fujita M, Schuchter L, Unciti-Broceta A, Brunton VG, Patton EE.

Cell Chem Biol. 2018 Dec 20;25(12):1456-1469.e6. doi: 10.1016/j.chembiol.2018.09.005. Epub 2018 Oct 4.

24.

XenofilteR: computational deconvolution of mouse and human reads in tumor xenograft sequence data.

Kluin RJC, Kemper K, Kuilman T, de Ruiter JR, Iyer V, Forment JV, Cornelissen-Steijger P, de Rink I, Ter Brugge P, Song JY, Klarenbeek S, McDermott U, Jonkers J, Velds A, Adams DJ, Peeper DS, Krijgsman O.

BMC Bioinformatics. 2018 Oct 4;19(1):366. doi: 10.1186/s12859-018-2353-5.

25.

Sixteen diverse laboratory mouse reference genomes define strain-specific haplotypes and novel functional loci.

Lilue J, Doran AG, Fiddes IT, Abrudan M, Armstrong J, Bennett R, Chow W, Collins J, Collins S, Czechanski A, Danecek P, Diekhans M, Dolle DD, Dunn M, Durbin R, Earl D, Ferguson-Smith A, Flicek P, Flint J, Frankish A, Fu B, Gerstein M, Gilbert J, Goodstadt L, Harrow J, Howe K, Ibarra-Soria X, Kolmogorov M, Lelliott CJ, Logan DW, Loveland J, Mathews CE, Mott R, Muir P, Nachtweide S, Navarro FCP, Odom DT, Park N, Pelan S, Pham SK, Quail M, Reinholdt L, Romoth L, Shirley L, Sisu C, Sjoberg-Herrera M, Stanke M, Steward C, Thomas M, Threadgold G, Thybert D, Torrance J, Wong K, Wood J, Yalcin B, Yang F, Adams DJ, Paten B, Keane TM.

Nat Genet. 2018 Nov;50(11):1574-1583. doi: 10.1038/s41588-018-0223-8. Epub 2018 Oct 1.

PMID:
30275530
26.

A synthesis approach of mouse studies to identify genes and proteins in arterial thrombosis and bleeding.

Baaten CCFMJ, Meacham S, de Witt SM, Feijge MAH, Adams DJ, Akkerman JN, Cosemans JMEM, Grassi L, Jupe S, Kostadima M, Mattheij NJA, Prins MH, Ramirez-Solis R, Soehnlein O, Swieringa F, Weber C, White JK, Ouwehand WH, Heemskerk JWM.

Blood. 2018 Dec 13;132(24):e35-e46. doi: 10.1182/blood-2018-02-831982. Epub 2018 Oct 1.

PMID:
30275110
27.

A lentiviral vector-based insertional mutagenesis screen identifies mechanisms of resistance to MAPK inhibitors in melanoma.

Ranzani M, Alifrangis C, Thompson NA, Rust AG, Allahyar A, Iyer V, Price S, Ellis P, Turner G, de Ridder J, McDermott U, Adams DJ.

Pigment Cell Melanoma Res. 2019 Mar;32(2):332-335. doi: 10.1111/pcmr.12737. Epub 2018 Oct 19. No abstract available.

PMID:
30218636
28.

Aligning self-assembled perylene bisimides in a magnetic field.

Draper ER, Wallace M, Honecker D, Adams DJ.

Chem Commun (Camb). 2018 Sep 27;54(78):10977-10980. doi: 10.1039/c8cc05968c.

PMID:
30209449
29.

Case study: patient-derived clear cell adenocarcinoma xenograft model longitudinally predicts treatment response.

Vargas R, Gopal P, Kuzmishin GB, DeBernardo R, Koyfman SA, Jha BK, Mian OY, Scott J, Adams DJ, Peacock CD, Abazeed ME.

NPJ Precis Oncol. 2018 Jul 11;2:14. doi: 10.1038/s41698-018-0060-3. eCollection 2018.

30.

Novel analgesic ω-conotoxins from the vermivorous cone snail Conus moncuri provide new insights into the evolution of conopeptides.

Sousa SR, McArthur JR, Brust A, Bhola RF, Rosengren KJ, Ragnarsson L, Dutertre S, Alewood PF, Christie MJ, Adams DJ, Vetter I, Lewis RJ.

Sci Rep. 2018 Sep 7;8(1):13397. doi: 10.1038/s41598-018-31245-4.

31.

Phase I Study of the Combination of Bendamustine, Rituximab, and Pixantrone in Patients With Relapsed/Refractory B-cell Non-Hodgkin Lymphoma.

Heyman B, Rizzieri D, Adams DJ, De Castro C, Diehl L, Li Z, Moore J, Beaven A.

Clin Lymphoma Myeloma Leuk. 2018 Oct;18(10):679-686. doi: 10.1016/j.clml.2018.07.285. Epub 2018 Jul 29.

PMID:
30166257
32.

Chemical Screening Identifies Enhancers of Mutant Oligodendrocyte Survival and Unmasks a Distinct Pathological Phase in Pelizaeus-Merzbacher Disease.

Elitt MS, Shick HE, Madhavan M, Allan KC, Clayton BLL, Weng C, Miller TE, Factor DC, Barbar L, Nawash BS, Nevin ZS, Lager AM, Li Y, Jin F, Adams DJ, Tesar PJ.

Stem Cell Reports. 2018 Sep 11;11(3):711-726. doi: 10.1016/j.stemcr.2018.07.015. Epub 2018 Aug 23.

33.

Ingesting Self-Grown Produce and Seropositivity for Hepatitis E in the United States.

Diehl TM, Adams DJ, Nylund CM.

Gastroenterol Res Pract. 2018 Jul 15;2018:7980413. doi: 10.1155/2018/7980413. eCollection 2018.

34.
35.

Pulmonary metastatic colonisation and granulomas in NOX2-deficient mice.

van der Weyden L, Speak AO, Swiatkowska A, Clare S, Schejtman A, Santilli G, Arends MJ, Adams DJ.

J Pathol. 2018 Nov;246(3):300-310. doi: 10.1002/path.5140. Epub 2018 Sep 19.

36.

Accumulation of 8,9-unsaturated sterols drives oligodendrocyte formation and remyelination.

Hubler Z, Allimuthu D, Bederman I, Elitt MS, Madhavan M, Allan KC, Shick HE, Garrison E, T Karl M, Factor DC, Nevin ZS, Sax JL, Thompson MA, Fedorov Y, Jin J, Wilson WK, Giera M, Bracher F, Miller RH, Tesar PJ, Adams DJ.

Nature. 2018 Aug;560(7718):372-376. doi: 10.1038/s41586-018-0360-3. Epub 2018 Jul 25.

PMID:
30046109
37.

Surface-Mediated Supramolecular Self-Assembly of Protein, Peptide, and Nucleoside Derivatives: From Surface Design to the Underlying Mechanism and Tailored Functions.

Yang B, Adams DJ, Marlow M, Zelzer M.

Langmuir. 2018 Dec 18;34(50):15109-15125. doi: 10.1021/acs.langmuir.8b01165. Epub 2018 Aug 6.

PMID:
30032622
38.

Role of CysI-CysIII Disulfide Bond on the Structure and Activity of α-Conotoxins at Human Neuronal Nicotinic Acetylcholine Receptors.

Tabassum N, Tae HS, Jia X, Kaas Q, Jiang T, Adams DJ, Yu R.

ACS Omega. 2017 Aug 31;2(8):4621-4631. doi: 10.1021/acsomega.7b00639. Epub 2017 Aug 17.

39.

Stoichiometry dependent inhibition of rat α3β4 nicotinic acetylcholine receptor by the ribbon isomer of α-conotoxin AuIB.

Wu X, Tae HS, Huang YH, Adams DJ, Craik DJ, Kaas Q.

Biochem Pharmacol. 2018 Sep;155:288-297. doi: 10.1016/j.bcp.2018.07.007. Epub 2018 Jul 21.

PMID:
30009767
40.

A Requirement for Zic2 in the Regulation of Nodal Expression Underlies the Establishment of Left-Sided Identity.

Dykes IM, Szumska D, Kuncheria L, Puliyadi R, Chen CM, Papanayotou C, Lockstone H, Dubourg C, David V, Schneider JE, Keane TM, Adams DJ, Brown SDM, Mercier S, Odent S, Collignon J, Bhattacharya S.

Sci Rep. 2018 Jul 11;8(1):10439. doi: 10.1038/s41598-018-28714-1.

41.

No unexpected CRISPR-Cas9 off-target activity revealed by trio sequencing of gene-edited mice.

Iyer V, Boroviak K, Thomas M, Doe B, Riva L, Ryder E, Adams DJ.

PLoS Genet. 2018 Jul 9;14(7):e1007503. doi: 10.1371/journal.pgen.1007503. eCollection 2018 Jul.

42.

Mutational Analysis Identifies Therapeutic Biomarkers in Inflammatory Bowel Disease-Associated Colorectal Cancers.

Din S, Wong K, Mueller MF, Oniscu A, Hewinson J, Black CJ, Miller ML, Jiménez-Sánchez A, Rabbie R, Rashid M, Satsangi J, Adams DJ, Arends MJ.

Clin Cancer Res. 2018 Oct 15;24(20):5133-5142. doi: 10.1158/1078-0432.CCR-17-3713. Epub 2018 Jun 27.

PMID:
29950348
43.

Controlled Tuning of the Properties in Optoelectronic Self-Sorted Gels.

Cross ER, Sproules S, Schweins R, Draper ER, Adams DJ.

J Am Chem Soc. 2018 Jul 18;140(28):8667-8670. doi: 10.1021/jacs.8b05359. Epub 2018 Jul 3.

44.

Responses to spaceflight of mouse mandibular bone and teeth.

Dagdeviren D, Kalajzic Z, Adams DJ, Kalajzic I, Lurie A, Mednieks MI, Hand AR.

Arch Oral Biol. 2018 Jun 7;93:163-176. doi: 10.1016/j.archoralbio.2018.06.008. [Epub ahead of print]

PMID:
29929058
45.

Exploring Rubric-Related Multidimensionality in Polytomously Scored Test Items.

Bolt DM, Adams DJ.

Appl Psychol Meas. 2017 May;41(3):163-177. doi: 10.1177/0146621616677715. Epub 2016 Nov 24.

46.

Publisher Correction: Mutations in Vps15 perturb neuronal migration in mice and are associated with neurodevelopmental disease in humans.

Gstrein T, Edwards A, Přistoupilová A, Leca I, Breuss M, Pilat-Carotta S, Hansen AH, Tripathy R, Traunbauer AK, Hochstoeger T, Rosoklija G, Repic M, Landler L, Stránecký V, Dürnberger G, Keane TM, Zuber J, Adams DJ, Flint J, Honzik T, Gut M, Beltran S, Mechtler K, Sherr E, Kmoch S, Gut I, Keays DA.

Nat Neurosci. 2018 Aug;21(8):1139. doi: 10.1038/s41593-018-0170-9.

PMID:
29875394
47.

Detector for positronium temperature measurements by two-photon angular correlation.

Cecchini GG, Jones ACL, Fuentes-Garcia M, Adams DJ, Austin M, Membreno E, Mills AP Jr.

Rev Sci Instrum. 2018 May;89(5):053106. doi: 10.1063/1.5017724.

PMID:
29864868
48.

The murine hepatic sequelae of long-term ethanol consumption are sex-specific and exacerbated by Aldh1b1 loss.

Müller MF, Kendall TJ, Adams DJ, Zhou Y, Arends MJ.

Exp Mol Pathol. 2018 Aug;105(1):63-70. doi: 10.1016/j.yexmp.2018.05.008. Epub 2018 Jun 1.

PMID:
29859945
49.

Renal cell carcinoma in a cat with polycystic kidney disease undergoing renal transplantation.

Adams DJ, Demchur JA, Aronson LR.

JFMS Open Rep. 2018 May 4;4(1):2055116918766152. doi: 10.1177/2055116918766152. eCollection 2018 Jan-Jun.

50.

Supramolecular Nucleoside-Based Gel: Molecular Dynamics Simulation and Characterization of Its Nanoarchitecture and Self-Assembly Mechanism.

Angelerou MGF, Frederix PWJM, Wallace M, Yang B, Rodger A, Adams DJ, Marlow M, Zelzer M.

Langmuir. 2018 Jun 12;34(23):6912-6921. doi: 10.1021/acs.langmuir.8b00646. Epub 2018 May 29. Erratum in: Langmuir. 2019 Feb 19;35(7):2885.

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