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Non-invasive early detection of acute transplant rejection via nanosensors of granzyme B activity.

Mac QD, Mathews DV, Kahla JA, Stoffers CM, Delmas OM, Holt BA, Adams AB, Kwong GA.

Nat Biomed Eng. 2019 Apr;3(4):281-291. doi: 10.1038/s41551-019-0358-7. Epub 2019 Feb 18.


Long-term survival of pig-to-rhesus macaque renal xenografts is dependent on CD4 T cell depletion.

Kim SC, Mathews DV, Breeden CP, Higginbotham LB, Ladowski J, Martens G, Stephenson A, Farris AB, Strobert EA, Jenkins J, Walters EM, Larsen CP, Tector M, Tector AJ, Adams AB.

Am J Transplant. 2019 Mar 1. doi: 10.1111/ajt.15329. [Epub ahead of print]


Celebrating 20 years of progress: accelerating towards elimination.

Sarah V, Adams AB, Jesudason T.

Community Eye Health. 2018;31(103):73. No abstract available.


CD122 signaling in CD8+ memory T cells drives costimulation-independent rejection.

Mathews DV, Dong Y, Higginbotham LB, Kim SC, Breeden CP, Stobert EA, Jenkins J, Tso JY, Larsen CP, Adams AB.

J Clin Invest. 2018 Oct 1;128(10):4557-4572. doi: 10.1172/JCI95914. Epub 2018 Sep 17.


Xenoantigen Deletion and Chemical Immunosuppression Can Prolong Renal Xenograft Survival.

Adams AB, Kim SC, Martens GR, Ladowski JM, Estrada JL, Reyes LM, Breeden C, Stephenson A, Eckhoff DE, Tector M, Tector AJ.

Ann Surg. 2018 Oct;268(4):564-573. doi: 10.1097/SLA.0000000000002977.


Positional effects on the distributions of ventilation and end-expiratory gas volume in the asymmetric chest-a quantitative lung computed tomographic analysis.

Cortes-Puentes GA, Gard KE, Adams AB, Dries DJ, Quintel M, Oeckler RA, Gattinoni L, Marini JJ.

Intensive Care Med Exp. 2018 Apr 10;6(1):9. doi: 10.1186/s40635-018-0175-4.


Alterations in Intestinal Microbiota Lead to Production of Interleukin 17 by Intrahepatic γδ T-Cell Receptor-Positive Cells and Pathogenesis of Cholestatic Liver Disease.

Tedesco D, Thapa M, Chin CY, Ge Y, Gong M, Li J, Gumber S, Speck P, Elrod EJ, Burd EM, Kitchens WH, Magliocca JF, Adams AB, Weiss DS, Mohamadzadeh M, Grakoui A.

Gastroenterology. 2018 Jun;154(8):2178-2193. doi: 10.1053/j.gastro.2018.02.019. Epub 2018 Feb 15.


Biomarkers of operational tolerance following kidney transplantation - The immune tolerance network studies of spontaneously tolerant kidney transplant recipients.

Newell KA, Adams AB, Turka LA.

Hum Immunol. 2018 May;79(5):380-387. doi: 10.1016/j.humimm.2018.02.007. Epub 2018 Feb 12. Review.


PEEP titration: the effect of prone position and abdominal pressure in an ARDS model.

Keenan JC, Cortes-Puentes GA, Zhang L, Adams AB, Dries DJ, Marini JJ.

Intensive Care Med Exp. 2018 Jan 30;6(1):3. doi: 10.1186/s40635-018-0170-9.


What's hot, what's new: Report from the American Transplant Congress 2017.

Cooper M, Li XC, Adams AB.

Am J Transplant. 2018 Feb;18(2):308-320. doi: 10.1111/ajt.14628. Epub 2018 Jan 21.


Emergency department use among kidney transplant recipients in the United States.

Lovasik BP, Zhang R, Hockenberry JM, Schrager JD, Pastan SO, Adams AB, Mohan S, Larsen CP, Patzer RE.

Am J Transplant. 2018 Apr;18(4):868-880. doi: 10.1111/ajt.14578. Epub 2017 Dec 20.


Transplantation Versus Resection for Hilar Cholangiocarcinoma: An Argument for Shifting Treatment Paradigms for Resectable Disease.

Ethun CG, Lopez-Aguiar AG, Anderson DJ, Adams AB, Fields RC, Doyle MB, Chapman WC, Krasnick BA, Weber SM, Mezrich JD, Salem A, Pawlik TM, Poultsides G, Tran TB, Idrees K, Isom CA, Martin RCG, Scoggins CR, Shen P, Mogal HD, Schmidt C, Beal E, Hatzaras I, Shenoy R, Cardona K, Maithel SK.

Ann Surg. 2018 May;267(5):797-805. doi: 10.1097/SLA.0000000000002574.


Pluripotent stem cells that evade the immune radar.

Kim SC, Adams AB.

Nat Biotechnol. 2017 Aug 8;35(8):722-723. doi: 10.1038/nbt.3940. No abstract available.


Alloimmunity But Not Viral Immunity Promotes Allograft Loss in a Mouse Model of Polyomavirus-Associated Allograft Injury.

Kim SC, Wang J, Dong Y, Mathews DV, Albrecht JA, Breeden CP, Farris AB, Lukacher AE, Ford ML, Newell KA, Adams AB.

Transplant Direct. 2017 May 12;3(6):e161. doi: 10.1097/TXD.0000000000000677. eCollection 2017 Jun.


Hospitalization Among Individuals Waitlisted For Kidney Transplant.

Newman KL, Lynch RJ, Adams AB, Zhang R, Pastan SO, Patzer RE.

Transplantation. 2017 Dec;101(12):2913-2923. doi: 10.1097/TP.0000000000001839.


Belatacept Combined With Transient Calcineurin Inhibitor Therapy Prevents Rejection and Promotes Improved Long-Term Renal Allograft Function.

Adams AB, Goldstein J, Garrett C, Zhang R, Patzer RE, Newell KA, Turgeon NA, Chami AS, Guasch A, Kirk AD, Pastan SO, Pearson TC, Larsen CP.

Am J Transplant. 2017 Nov;17(11):2922-2936. doi: 10.1111/ajt.14353. Epub 2017 Jul 3.


Belatacept-Resistant Rejection Is Associated With CD28+ Memory CD8 T Cells.

Mathews DV, Wakwe WC, Kim SC, Lowe MC, Breeden C, Roberts ME, Farris AB, Strobert EA, Jenkins JB, Larsen CP, Ford ML, Townsend R, Adams AB.

Am J Transplant. 2017 Sep;17(9):2285-2299. doi: 10.1111/ajt.14349. Epub 2017 Jul 11.


Increased Pretransplant Frequency of CD28+ CD4+ TEM Predicts Belatacept-Resistant Rejection in Human Renal Transplant Recipients.

Cortes-Cerisuelo M, Laurie SJ, Mathews DV, Winterberg PD, Larsen CP, Adams AB, Ford ML.

Am J Transplant. 2017 Sep;17(9):2350-2362. doi: 10.1111/ajt.14350. Epub 2017 Jun 30.


Interruption of OX40L signaling prevents costimulation blockade-resistant allograft rejection.

Kitchens WH, Dong Y, Mathews DV, Breeden CP, Strobert E, Fuentes ME, Larsen CP, Ford ML, Adams AB.

JCI Insight. 2017 Mar 9;2(5):e90317. doi: 10.1172/jci.insight.90317.


Fc-Silent Anti-CD154 Domain Antibody Effectively Prevents Nonhuman Primate Renal Allograft Rejection.

Kim SC, Wakwe W, Higginbotham LB, Mathews DV, Breeden CP, Stephenson AC, Jenkins J, Strobert E, Price K, Price L, Kuhn R, Wang H, Yamniuk A, Suchard S, Farris AB 3rd, Pearson TC, Larsen CP, Ford ML, Suri A, Nadler S, Adams AB.

Am J Transplant. 2017 May;17(5):1182-1192. doi: 10.1111/ajt.14197. Epub 2017 Feb 25.


The Effect of Compartmental Asymmetry on the Monitoring of Pulmonary Mechanics and Lung Volumes.

Keenan JC, Cortes-Puentes GA, Adams AB, Dries DJ, Marini JJ.

Respir Care. 2016 Nov;61(11):1536-1542. Epub 2016 Oct 18.


CD4+ Foxp3+ T cells promote aberrant immunoglobulin G production and maintain CD8+ T-cell suppression during chronic liver disease.

Tedesco D, Thapa M, Gumber S, Elrod EJ, Rahman K, Ibegbu CC, Magliocca JF, Adams AB, Anania F, Grakoui A.

Hepatology. 2017 Feb;65(2):661-677. doi: 10.1002/hep.28894. Epub 2016 Dec 19.


First-Year Waitlist Hospitalization and Subsequent Waitlist and Transplant Outcome.

Lynch RJ, Zhang R, Patzer RE, Larsen CP, Adams AB.

Am J Transplant. 2017 Apr;17(4):1031-1041. doi: 10.1111/ajt.14061. Epub 2016 Oct 24.


Costimulation Blockade in Autoimmunity and Transplantation: The CD28 Pathway.

Adams AB, Ford ML, Larsen CP.

J Immunol. 2016 Sep 15;197(6):2045-50. doi: 10.4049/jimmunol.1601135. Review.


The Knife's Edge of Tolerance: Inducing Stable Multilineage Mixed Chimerism but With a Significant Risk of CMV Reactivation and Disease in Rhesus Macaques.

Zheng HB, Watkins B, Tkachev V, Yu S, Tran D, Furlan S, Zeleski K, Singh K, Hamby K, Hotchkiss C, Lane J, Gumber S, Adams AB, Cendales L, Kirk AD, Kaur A, Blazar BR, Larsen CP, Kean LS.

Am J Transplant. 2017 Mar;17(3):657-670. doi: 10.1111/ajt.14006. Epub 2016 Sep 19.


Reliability of transpulmonary pressure-time curve profile to identify tidal recruitment/hyperinflation in experimental unilateral pleural effusion.

Formenti P, Umbrello M, Graf J, Adams AB, Dries DJ, Marini JJ.

J Clin Monit Comput. 2017 Aug;31(4):783-791. doi: 10.1007/s10877-016-9908-7. Epub 2016 Jul 20.


Development of Third-generation Cocal Envelope Producer Cell Lines for Robust Lentiviral Gene Transfer into Hematopoietic Stem Cells and T-cells.

Humbert O, Gisch DW, Wohlfahrt ME, Adams AB, Greenberg PD, Schmitt TM, Trobridge GD, Kiem HP.

Mol Ther. 2016 Aug;24(7):1237-46. doi: 10.1038/mt.2016.70. Epub 2016 Apr 8.


Transplantation tolerance: Coming of age.

Adams AB, Newell KA.

Hepatology. 2016 Aug;64(2):347-9. doi: 10.1002/hep.28553. Epub 2016 May 17. No abstract available.


Racial/Ethnic Differences in the Association Between Hospitalization and Kidney Transplantation Among Waitlisted End-Stage Renal Disease Patients.

Newman KL, Fedewa SA, Jacobson MH, Adams AB, Zhang R, Pastan SO, Patzer RE.

Transplantation. 2016 Dec;100(12):2735-2745.


Waitlist Hospital Admissions Predict Resource Utilization and Survival After Renal Transplantation.

Lynch RJ, Zhang R, Patzer RE, Larsen CP, Adams AB.

Ann Surg. 2016 Dec;264(6):1168-1173.


Nonhuman primate models of transplant tolerance: closer to the holy grail.

Kitchens WH, Adams AB.

Curr Opin Organ Transplant. 2016 Feb;21(1):59-65. doi: 10.1097/MOT.0000000000000271. Review.


Antibody-Mediated Rejection in Sensitized Nonhuman Primates: Modeling Human Biology.

Burghuber CK, Kwun J, Page EJ, Manook M, Gibby AC, Leopardi FV, Song M, Farris AB 3rd, Hong JJ, Villinger F, Adams AB, Iwakoshi NN, Knechtle SJ.

Am J Transplant. 2016 Jun;16(6):1726-38. doi: 10.1111/ajt.13688. Epub 2016 Mar 25.


Simple screening tool for assessing attention deficit in pediatric lupus.

Nuruzzaman F, Sherman Y, Ostfeld BM, Adams AB, Pan N, Barinstein LV, Lehman TJ, Moorthy LN.

Lupus. 2016 Apr;25(4):447-8. doi: 10.1177/0961203315619032. Epub 2015 Dec 3. No abstract available.


Preventing T cell rejection of pig xenografts.

Higginbotham L, Ford ML, Newell KA, Adams AB.

Int J Surg. 2015 Nov;23(Pt B):285-290. doi: 10.1016/j.ijsu.2015.07.722. Epub 2015 Aug 22. Review.


Impact of Chest Wall Modifications and Lung Injury on the Correspondence Between Airway and Transpulmonary Driving Pressures.

Cortes-Puentes GA, Keenan JC, Adams AB, Parker ED, Dries DJ, Marini JJ.

Crit Care Med. 2015 Aug;43(8):e287-95. doi: 10.1097/CCM.0000000000001036.


Unrecognized Celiac Disease in Children Presenting for Rheumatology Evaluation.

Sherman Y, Karanicolas R, DiMarco B, Pan N, Adams AB, Barinstein LV, Moorthy LN, Lehman TJ.

Pediatrics. 2015 Jul;136(1):e68-75. doi: 10.1542/peds.2014-2379. Epub 2015 Jun 15.


A randomized, placebo-controlled trial of lubiprostone for opioid-induced constipation in chronic noncancer pain.

Jamal MM, Adams AB, Jansen JP, Webster LR.

Am J Gastroenterol. 2015 May;110(5):725-32. doi: 10.1038/ajg.2015.106. Epub 2015 Apr 28.


Pre-transplant antibody screening and anti-CD154 costimulation blockade promote long-term xenograft survival in a pig-to-primate kidney transplant model.

Higginbotham L, Mathews D, Breeden CA, Song M, Farris AB 3rd, Larsen CP, Ford ML, Lutz AJ, Tector M, Newell KA, Tector AJ, Adams AB.

Xenotransplantation. 2015 May-Jun;22(3):221-30. doi: 10.1111/xen.12166. Epub 2015 Apr 3.


Systems biological analyses reveal the hepatitis C virus (HCV)-specific regulation of hematopoietic development.

Velazquez VM, Uebelhoer LS, Thapa M, Ibegbu CC, Courtney C, Bosinger SE, Magliocca JF, Adams AB, Kirk AD, Knechtle SJ, Kalman D, Suthar MS, Grakoui A.

Hepatology. 2015 Mar;61(3):843-56. doi: 10.1002/hep.27575. Epub 2015 Jan 30.


Evaluation of intraosseous pressure in a hypovolemic animal model.

Frascone RJ, Salzman JG, Adams AB, Bliss P, Wewerka SS, Dries DJ.

J Surg Res. 2015 Jan;193(1):383-90. doi: 10.1016/j.jss.2014.07.007. Epub 2014 Jul 7.


Belatacept: is there BENEFIT for liver transplantation too?

Knechtle SJ, Adams AB.

Am J Transplant. 2014 Aug;14(8):1717-8.


No evidence of clonal dominance after transplant of HOXB4-expanded cord blood cells in a nonhuman primate model.

Watts KL, Beard BC, Wood BL, Trobridge GD, Humphries RK, Adams AB, Nelson V, Kiem HP.

Exp Hematol. 2014 Jul;42(7):497-504. doi: 10.1016/j.exphem.2014.03.007. Epub 2014 Apr 2.


Transplant versus resection for the management of hepatocellular carcinoma meeting Milan Criteria in the MELD exception era at a single institution in a UNOS region with short wait times.

Squires MH 3rd, Hanish SI, Fisher SB, Garrett C, Kooby DA, Sarmiento JM, Cardona K, Adams AB, Russell MC, Magliocca JF, Knechtle SJ, Staley CA 3rd, Maithel SK.

J Surg Oncol. 2014 May;109(6):533-41. doi: 10.1002/jso.23531. Epub 2013 Dec 17.


Disparities in unmet dental need and dental care received by pregnant women in Maryland.

Singhal A, Chattopadhyay A, Garcia AI, Adams AB, Cheng D.

Matern Child Health J. 2014 Sep;18(7):1658-66. doi: 10.1007/s10995-013-1406-7.


The emerging role of TH17 cells in organ transplantation.

Sullivan JA, Adams AB, Burlingham WJ.

Transplantation. 2014 Mar 15;97(5):483-9. doi: 10.1097/TP.0000000000000000. Review.


Targeting co-stimulatory pathways: transplantation and autoimmunity.

Ford ML, Adams AB, Pearson TC.

Nat Rev Nephrol. 2014 Jan;10(1):14-24. doi: 10.1038/nrneph.2013.183. Epub 2013 Oct 8. Review.


Value and limitations of transpulmonary pressure calculations during intra-abdominal hypertension.

Cortes-Puentes GA, Gard KE, Adams AB, Faltesek KA, Anderson CP, Dries DJ, Marini JJ.

Crit Care Med. 2013 Aug;41(8):1870-7. doi: 10.1097/CCM.0b013e31828a3bea.


Experimental intra-abdominal hypertension influences airway pressure limits for lung protective mechanical ventilation.

Cortes-Puentes GA, Cortes-Puentes LA, Adams AB, Anderson CP, Marini JJ, Dries DJ.

J Trauma Acute Care Surg. 2013 Jun;74(6):1468-73. doi: 10.1097/TA.0b013e31829243a7.


A blinded, randomized, controlled trial of three doses of high-dose insulin in poison-induced cardiogenic shock.

Cole JB, Stellpflug SJ, Ellsworth H, Anderson CP, Adams AB, Engebretsen KM, Holger JS.

Clin Toxicol (Phila). 2013 May;51(4):201-7. doi: 10.3109/15563650.2013.770152. Epub 2013 Mar 26. Erratum in: Clin Toxicol (Phila). 2013 Dec;51(10):1246.


A novel monoclonal antibody to CD40 prolongs islet allograft survival.

Lowe M, Badell IR, Thompson P, Martin B, Leopardi F, Strobert E, Price AA, Abdulkerim HS, Wang R, Iwakoshi NN, Adams AB, Kirk AD, Larsen CP, Reimann KA.

Am J Transplant. 2012 Aug;12(8):2079-87. doi: 10.1111/j.1600-6143.2012.04054.x. Epub 2012 May 8.

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