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Items: 1 to 50 of 63

1.

SHP2 Drives Adaptive Resistance to ERK Signaling Inhibition in Molecularly Defined Subsets of ERK-Dependent Tumors.

Ahmed TA, Adamopoulos C, Karoulia Z, Wu X, Sachidanandam R, Aaronson SA, Poulikakos PI.

Cell Rep. 2019 Jan 2;26(1):65-78.e5. doi: 10.1016/j.celrep.2018.12.013.

2.

Polycystin-1 downregulation induces ERK-dependent mTOR pathway activation in a cellular model of psoriasis.

Gargalionis AN, Malakou LS, Adamopoulos C, Piperi C, Theohari I, Nokhbehsaim M, Deschner J, Kokkalis G, Korkolopoulou P, Papadavid E, Papavassiliou AG, Basdra EK.

Biochim Biophys Acta Mol Basis Dis. 2018 Oct;1864(10):3468-3476. doi: 10.1016/j.bbadis.2018.07.036. Epub 2018 Aug 2.

PMID:
30077613
3.

Diabetes Worsens Skeletal Muscle Mitochondrial Function, Oxidative Stress, and Apoptosis After Lower-Limb Ischemia-Reperfusion: Implication of the RISK and SAFE Pathways?

Pottecher J, Adamopoulos C, Lejay A, Bouitbir J, Charles AL, Meyer A, Singer M, Wolff V, Diemunsch P, Laverny G, Metzger D, Geny B.

Front Physiol. 2018 May 22;9:579. doi: 10.3389/fphys.2018.00579. eCollection 2018.

4.

Similar clinical benefits from below-target and target dose enalapril in patients with heart failure in the SOLVD Treatment trial.

Lam PH, Dooley DJ, Fonarow GC, Butler J, Bhatt DL, Filippatos GS, Deedwania P, Forman DE, White M, Fletcher RD, Arundel C, Blackman MR, Adamopoulos C, Kanonidis IE, Aban IB, Patel K, Aronow WS, Allman RM, Anker SD, Pitt B, Ahmed A.

Eur J Heart Fail. 2018 Feb;20(2):359-369. doi: 10.1002/ejhf.937. Epub 2017 Oct 5.

PMID:
28980368
5.

Advanced glycation end products interfere in luteinizing hormone and follicle stimulating hormone signaling in human granulosa KGN cells.

Kandaraki EA, Chatzigeorgiou A, Papageorgiou E, Piperi C, Adamopoulos C, Papavassiliou AG, Koutsilieris M, Diamanti-Kandarakis E.

Exp Biol Med (Maywood). 2018 Jan;243(1):29-33. doi: 10.1177/1535370217731288. Epub 2017 Sep 15.

6.

Potential of glycative stress targeting for cancer prevention.

Piperi C, Adamopoulos C, Papavassiliou AG.

Cancer Lett. 2017 Apr 1;390:153-159. doi: 10.1016/j.canlet.2017.01.020. Epub 2017 Jan 19. Review.

PMID:
28111136
7.

Signaling mechanisms implicated in cranial sutures pathophysiology: Craniosynostosis.

Katsianou MA, Adamopoulos C, Vastardis H, Basdra EK.

BBA Clin. 2016 Apr 29;6:165-176. eCollection 2016 Dec. Review.

8.

Mechanosensor polycystin-1 potentiates differentiation of human osteoblastic cells by upregulating Runx2 expression via induction of JAK2/STAT3 signaling axis.

Dalagiorgou G, Piperi C, Adamopoulos C, Georgopoulou U, Gargalionis AN, Spyropoulou A, Zoi I, Nokhbehsaim M, Damanaki A, Deschner J, Basdra EK, Papavassiliou AG.

Cell Mol Life Sci. 2017 Mar;74(5):921-936. doi: 10.1007/s00018-016-2394-8. Epub 2016 Oct 3.

PMID:
27699453
9.

RANKL Signaling and ErbB Receptors in Breast Carcinogenesis.

Zoi I, Karamouzis MV, Adamopoulos C, Papavassiliou AG.

Trends Mol Med. 2016 Oct;22(10):839-850. doi: 10.1016/j.molmed.2016.07.009. Epub 2016 Aug 23. Review.

PMID:
27567286
10.

Recent Advances in Mechanobiology of Osteosarcoma.

Adamopoulos C, Gargalionis AN, Piperi C, Papavassiliou AG.

J Cell Biochem. 2017 Feb;118(2):232-236. doi: 10.1002/jcb.25660. Epub 2016 Aug 16. Review.

PMID:
27463370
11.

Pivotal role of high-mobility group box 1 (HMGB1) signaling pathways in glioma development and progression.

Angelopoulou E, Piperi C, Adamopoulos C, Papavassiliou AG.

J Mol Med (Berl). 2016 Aug;94(8):867-74. doi: 10.1007/s00109-016-1435-y. Epub 2016 Jun 4. Review.

PMID:
27262996
12.

Systemic effects of AGEs in ER stress induction in vivo.

Adamopoulos C, Mihailidou C, Grivaki C, Papavassiliou KA, Kiaris H, Piperi C, Papavassiliou AG.

Glycoconj J. 2016 Aug;33(4):537-44. doi: 10.1007/s10719-016-9680-4. Epub 2016 May 28. Review.

PMID:
27236787
13.

Deciphering signaling networks in osteosarcoma pathobiology.

Adamopoulos C, Gargalionis AN, Basdra EK, Papavassiliou AG.

Exp Biol Med (Maywood). 2016 Jun;241(12):1296-305. doi: 10.1177/1535370216648806. Epub 2016 May 6. Review.

14.

Expression of Circulating Muscarinic Receptors in Infants With Severe Idiopathic Life-Threatening Events.

Adamopoulos C, Greney H, Beutelstetter M, Bousquet P, Livolsi A.

JAMA Pediatr. 2016 Jul 1;170(7):707-8. doi: 10.1001/jamapediatrics.2015.4762. No abstract available.

PMID:
27159641
15.

Clinical significance of AGE-RAGE axis in colorectal cancer: associations with glyoxalase-I, adiponectin receptor expression and prognosis.

Sakellariou S, Fragkou P, Levidou G, Gargalionis AN, Piperi C, Dalagiorgou G, Adamopoulos C, Saetta A, Agrogiannis G, Theohari I, Sougioultzis S, Tsioli P, Karavokyros I, Tsavaris N, Kostakis ID, Zizi-Serbetzoglou A, Vandoros GP, Patsouris E, Korkolopoulou P.

BMC Cancer. 2016 Mar 1;16:174. doi: 10.1186/s12885-016-2213-5.

16.

Potential role of AKT/mTOR signalling proteins in hairy cell leukaemia: association with BRAF/ERK activation and clinical outcome.

Lakiotaki E, Levidou G, Angelopoulou MK, Adamopoulos C, Pangalis G, Rassidakis G, Vassilakopoulos T, Gainaru G, Flevari P, Sachanas S, Saetta AA, Sepsa A, Moschogiannis M, Kalpadakis C, Tsesmetzis N, Milionis V, Chatziandreou I, Thymara I, Panayiotidis P, Dimopoulou M, Plata E, Konstantopoulos K, Patsouris E, Piperi C, Korkolopoulou P.

Sci Rep. 2016 Feb 19;6:21252. doi: 10.1038/srep21252.

17.

XBP1: A Pivotal Transcriptional Regulator of Glucose and Lipid Metabolism.

Piperi C, Adamopoulos C, Papavassiliou AG.

Trends Endocrinol Metab. 2016 Mar;27(3):119-122. doi: 10.1016/j.tem.2016.01.001. Epub 2016 Jan 20.

PMID:
26803729
18.

Targeting Androgen/Estrogen Receptors Crosstalk in Cancer.

Karamouzis MV, Papavassiliou KA, Adamopoulos C, Papavassiliou AG.

Trends Cancer. 2016 Jan;2(1):35-48. doi: 10.1016/j.trecan.2015.12.001. Epub 2015 Dec 31. Review.

PMID:
28741499
19.

Advanced glycation end products upregulate lysyl oxidase and endothelin-1 in human aortic endothelial cells via parallel activation of ERK1/2-NF-κB and JNK-AP-1 signaling pathways.

Adamopoulos C, Piperi C, Gargalionis AN, Dalagiorgou G, Spilioti E, Korkolopoulou P, Diamanti-Kandarakis E, Papavassiliou AG.

Cell Mol Life Sci. 2016 Apr;73(8):1685-98. doi: 10.1007/s00018-015-2091-z. Epub 2015 Dec 8.

PMID:
26646068
20.

Vascular Inflammation and Atherosclerosis: The Role of Estrogen Receptors.

Kassi E, Spilioti E, Nasiri-Ansari N, Adamopoulos C, Moutsatsou P, Papapanagiotou A, Siasos G, Tousoulis D, Papavassiliou AG.

Curr Med Chem. 2015;22(22):2651-65. Review.

PMID:
26051413
21.

Protein trafficking in colorectal carcinogenesis-targeting and bypassing resistance to currently applied treatments.

Gargalionis AN, Karamouzis MV, Adamopoulos C, Papavassiliou AG.

Carcinogenesis. 2015 Jun;36(6):607-15. doi: 10.1093/carcin/bgv052. Epub 2015 Apr 11. Review.

PMID:
25863128
22.

AGE/RAGE signalling regulation by miRNAs: associations with diabetic complications and therapeutic potential.

Piperi C, Goumenos A, Adamopoulos C, Papavassiliou AG.

Int J Biochem Cell Biol. 2015 Mar;60:197-201. doi: 10.1016/j.biocel.2015.01.009. Epub 2015 Jan 17. Review.

PMID:
25603271
23.

Emerging role of linker histone variant H1x as a biomarker with prognostic value in astrocytic gliomas. A multivariate analysis including trimethylation of H3K9 and H4K20.

Sepsa A, Levidou G, Gargalionis A, Adamopoulos C, Spyropoulou A, Dalagiorgou G, Thymara I, Boviatsis E, Themistocleous MS, Petraki K, Vrettakos G, Samaras V, Zisakis A, Patsouris E, Piperi C, Korkolopoulou P.

PLoS One. 2015 Jan 20;10(1):e0115101. doi: 10.1371/journal.pone.0115101. eCollection 2015.

24.

Expression of vascular endothelial factor-A, gelatinases (MMP-2, MMP-9) and TIMP-1 in uterine leiomyomas.

Korompelis P, Piperi C, Adamopoulos C, Dalagiorgou G, Korkolopoulou P, Sepsa A, Antsaklis A, Papavassiliou AG.

Clin Chem Lab Med. 2015 Aug;53(9):1415-24. doi: 10.1515/cclm-2014-0798.

PMID:
25470608
25.

Impact of atrial fibrillation and heart failure, independent of each other and in combination, on mortality in community-dwelling older adults.

Bajaj NS, Bhatia V, Sanam K, Ather S, Hashim T, Morgan C, Fonarow GC, Nanda NC, Prabhu SD, Adamopoulos C, Kheirbek R, Aronow WS, Fletcher RD, Anker SD, Ahmed A, Deedwania P.

Am J Cardiol. 2014 Sep 15;114(6):909-13. doi: 10.1016/j.amjcard.2014.05.045.

PMID:
25208562
26.

Polycystin-1 and polycystin-2 are involved in the acquisition of aggressive phenotypes in colorectal cancer.

Gargalionis AN, Korkolopoulou P, Farmaki E, Piperi C, Dalagiorgou G, Adamopoulos C, Levidou G, Saetta A, Fragkou P, Tsioli P, Kiaris H, Zizi-Serbetzoglou A, Karavokyros I, Papavassiliou KA, Tsavaris N, Patsouris E, Basdra EK, Papavassiliou AG.

Int J Cancer. 2015 Apr 1;136(7):1515-27. doi: 10.1002/ijc.29140. Epub 2014 Sep 3.

27.

Impact of dietary modification of advanced glycation end products (AGEs) on the hormonal and metabolic profile of women with polycystic ovary syndrome (PCOS).

Tantalaki E, Piperi C, Livadas S, Kollias A, Adamopoulos C, Koulouri A, Christakou C, Diamanti-Kandarakis E.

Hormones (Athens). 2014 Jan-Mar;13(1):65-73.

28.

The role of CXC-chemokine receptor CXCR2 and suppressor of cytokine signaling-3 (SOCS-3) in renal cell carcinoma.

Stofas A, Levidou G, Piperi C, Adamopoulos C, Dalagiorgou G, Bamias A, Karadimou A, Lainakis GA, Papadoukakis S, Stravodimos K, Dimopoulos MA, Patsouris E, Gakiopoulou H, Korkolopoulou P.

BMC Cancer. 2014 Mar 4;14:149. doi: 10.1186/1471-2407-14-149.

29.

Features of cardiac remodeling, associated with blood pressure and fibrosis biomarkers, are frequent in subjects with abdominal obesity.

Eschalier R, Rossignol P, Kearney-Schwartz A, Adamopoulos C, Karatzidou K, Fay R, Mandry D, Marie PY, Zannad F.

Hypertension. 2014 Apr;63(4):740-6. doi: 10.1161/HYPERTENSIONAHA.113.02419. Epub 2014 Jan 20.

PMID:
24446063
30.

Role of vitamin D in atherosclerosis.

Kassi E, Adamopoulos C, Basdra EK, Papavassiliou AG.

Circulation. 2013 Dec 3;128(23):2517-31. doi: 10.1161/CIRCULATIONAHA.113.002654. Review. No abstract available.

PMID:
24297817
31.

Role of histone lysine methyltransferases SUV39H1 and SETDB1 in gliomagenesis: modulation of cell proliferation, migration, and colony formation.

Spyropoulou A, Gargalionis A, Dalagiorgou G, Adamopoulos C, Papavassiliou KA, Lea RW, Piperi C, Papavassiliou AG.

Neuromolecular Med. 2014 Mar;16(1):70-82. doi: 10.1007/s12017-013-8254-x. Epub 2013 Aug 13.

PMID:
23943221
32.

Sox11 expression in astrocytic gliomas: correlation with nestin/c-Met/IDH1-R132H expression phenotypes, p-Stat-3 and survival.

Korkolopoulou P, Levidou G, El-Habr EA, Adamopoulos C, Fragkou P, Boviatsis E, Themistocleous MS, Petraki K, Vrettakos G, Sakalidou M, Samaras V, Zisakis A, Saetta A, Chatziandreou I, Patsouris E, Piperi C.

Br J Cancer. 2013 May 28;108(10):2142-52. doi: 10.1038/bjc.2013.176. Epub 2013 Apr 25.

33.

Advanced glycation end-products induce endoplasmic reticulum stress in human aortic endothelial cells.

Adamopoulos C, Farmaki E, Spilioti E, Kiaris H, Piperi C, Papavassiliou AG.

Clin Chem Lab Med. 2014 Jan 1;52(1):151-60. doi: 10.1515/cclm-2012-0826.

PMID:
23454718
34.

Polycystic ovary syndrome offspring display increased oxidative stress markers comparable to gestational diabetes offspring.

Boutzios G, Livadas S, Piperi C, Vitoratos N, Adamopoulos C, Hassiakos D, Iavazzo C, Diamanti-Kandarakis E.

Fertil Steril. 2013 Mar 1;99(3):943-50. doi: 10.1016/j.fertnstert.2012.10.050. Epub 2012 Nov 29.

PMID:
23200689
35.

Deregulated chromatin remodeling in the pathobiology of brain tumors.

Spyropoulou A, Piperi C, Adamopoulos C, Papavassiliou AG.

Neuromolecular Med. 2013 Mar;15(1):1-24. doi: 10.1007/s12017-012-8205-y. Review.

PMID:
23114751
36.

Mechanical stimulation of polycystin-1 induces human osteoblastic gene expression via potentiation of the calcineurin/NFAT signaling axis.

Dalagiorgou G, Piperi C, Georgopoulou U, Adamopoulos C, Basdra EK, Papavassiliou AG.

Cell Mol Life Sci. 2013 Jan;70(1):167-180. doi: 10.1007/s00018-012-1164-5. Epub 2012 Sep 27.

37.

Phosphorylated 4E-binding protein 1 (p-4E-BP1): a novel prognostic marker in human astrocytomas.

Korkolopoulou P, Levidou G, El-Habr EA, Piperi C, Adamopoulos C, Samaras V, Boviatsis E, Thymara I, Trigka EA, Sakellariou S, Kavantzas N, Patsouris E, Saetta AA.

Histopathology. 2012 Aug;61(2):293-305. doi: 10.1111/j.1365-2559.2012.04236.x. Epub 2012 Jun 13.

PMID:
22690797
38.

Three-dimensional imaging of pannus overgrowth after mitral valve repair.

Sachpekidis V, Agatziotis M, Styliadis I, Mosialos L, Kaprinis I, Monaghan MJ, Adamopoulos C.

Echocardiography. 2012 Sep;29(8):E210-3. doi: 10.1111/j.1540-8175.2012.01731.x. Epub 2012 May 29.

PMID:
22639921
39.

Histone modifications as a pathogenic mechanism of colorectal tumorigenesis.

Gargalionis AN, Piperi C, Adamopoulos C, Papavassiliou AG.

Int J Biochem Cell Biol. 2012 Aug;44(8):1276-89. doi: 10.1016/j.biocel.2012.05.002. Epub 2012 May 11. Review.

PMID:
22583735
40.

The Clinical and Prognostic Significance of Activated AKT-mTOR Pathway in Human Astrocytomas.

El Habr EA, Adamopoulos C, Levidou G, Saetta AA, Korkolopoulou P, Piperi C.

Neurol Res Int. 2012;2012:454957. doi: 10.1155/2012/454957. Epub 2012 Feb 21.

41.

Crosstalk between advanced glycation and endoplasmic reticulum stress: emerging therapeutic targeting for metabolic diseases.

Piperi C, Adamopoulos C, Dalagiorgou G, Diamanti-Kandarakis E, Papavassiliou AG.

J Clin Endocrinol Metab. 2012 Jul;97(7):2231-42. doi: 10.1210/jc.2011-3408. Epub 2012 Apr 16. Review.

PMID:
22508704
42.

Strong and positive association of endothelin-1 with AGEs in PCOS: a causal relationship or a bystander?

Christakou C, Economou F, Livadas S, Piperi C, Adamopoulos C, Marinakis E, Jdiamanti-Kandarakis E.

Hormones (Athens). 2011 Oct-Dec;10(4):292-7.

43.

Expression of interleukin-8 receptor CXCR2 and suppressor of cytokine signaling-3 in astrocytic tumors.

Korkolopoulou P, Levidou G, El-Habr EA, Adamopoulos C, Samaras V, Zisakis A, Kavantzas N, Boviatsis E, Fragkou P, Papavassiliou AG, Patsouris E, Piperi C.

Mol Med. 2012 May 9;18:379-88. doi: 10.2119/molmed.2011.00449.

44.

Right ventricular ejection fraction <20% is an independent predictor of mortality but not of hospitalization in older systolic heart failure patients.

Meyer P, Desai RV, Mujib M, Feller MA, Adamopoulos C, Banach M, Lainscak M, Aban I, White M, Aronow WS, Deedwania P, Iskandrian AE, Ahmed A.

Int J Cardiol. 2012 Feb 23;155(1):120-5. doi: 10.1016/j.ijcard.2011.05.046. Epub 2011 Jun 12.

45.

Relationship between left and right ventricular ejection fractions in chronic advanced systolic heart failure: insights from the BEST trial.

Desai RV, Meyer P, Ahmed MI, Mujib M, Adamopoulos C, White M, Aban IB, Iskandrian AE, Ahmed A.

Eur J Heart Fail. 2011 Apr;13(4):392-7. doi: 10.1093/eurjhf/hfq206. Epub 2010 Nov 21.

46.

Absence of obesity paradox in patients with chronic heart failure and diabetes mellitus: a propensity-matched study.

Adamopoulos C, Meyer P, Desai RV, Karatzidou K, Ovalle F, White M, Aban I, Love TE, Deedwania P, Anker SD, Ahmed A.

Eur J Heart Fail. 2011 Feb;13(2):200-6. doi: 10.1093/eurjhf/hfq159. Epub 2010 Oct 7.

47.

Timing of eplerenone initiation and outcomes in patients with heart failure after acute myocardial infarction complicated by left ventricular systolic dysfunction: insights from the EPHESUS trial.

Adamopoulos C, Ahmed A, Fay R, Angioi M, Filippatos G, Vincent J, Pitt B, Zannad F; EPHESUS Investigators.

Eur J Heart Fail. 2009 Nov;11(11):1099-105. doi: 10.1093/eurjhf/hfp136.

48.

High incidence of MGMT and RARbeta promoter methylation in primary glioblastomas: association with histopathological characteristics, inflammatory mediators and clinical outcome.

Piperi C, Themistocleous MS, Papavassiliou GA, Farmaki E, Levidou G, Korkolopoulou P, Adamopoulos C, Papavassiliou AG.

Mol Med. 2010 Jan-Feb;16(1-2):1-9. doi: 10.2119/molmed.2009.00140. Epub 2009 Oct 12.

49.

A propensity-matched study of elevated jugular venous pressure and outcomes in chronic heart failure.

Meyer P, Ekundayo OJ, Adamopoulos C, Mujib M, Aban I, White M, Aronow WS, Ahmed A.

Am J Cardiol. 2009 Mar 15;103(6):839-44. doi: 10.1016/j.amjcard.2008.11.045.

50.

Oral potassium supplement use and outcomes in chronic heart failure: a propensity-matched study.

Ekundayo OJ, Adamopoulos C, Ahmed MI, Pitt B, Young JB, Fleg JL, Love TE, Sui X, Perry GJ, Siscovick DS, Bakris G, Ahmed A.

Int J Cardiol. 2010 May 28;141(2):167-74. doi: 10.1016/j.ijcard.2008.11.195. Epub 2009 Jan 9.

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