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Items: 1 to 50 of 102

1.

Inflation of 430-parsec bipolar radio bubbles in the Galactic Centre by an energetic event.

Heywood I, Camilo F, Cotton WD, Yusef-Zadeh F, Abbott TD, Adam RM, Aldera MA, Bauermeister EF, Booth RS, Botha AG, Botha DH, Brederode LRS, Brits ZB, Buchner SJ, Burger JP, Chalmers JM, Cheetham T, de Villiers D, Dikgale-Mahlakoana MA, du Toit LJ, Esterhuyse SWP, Fanaroff BL, Foley AR, Fourie DJ, Gamatham RRG, Goedhart S, Gounden S, Hlakola MJ, Hoek CJ, Hokwana A, Horn DM, Horrell JMG, Hugo B, Isaacson AR, Jonas JL, Jordaan JDBL, Joubert AF, Józsa GIG, Julie RPM, Kapp FB, Kenyon JS, Kotzé PPA, Kriel H, Kusel TW, Lehmensiek R, Liebenberg D, Loots A, Lord RT, Lunsky BM, Macfarlane PS, Magnus LG, Magozore CM, Mahgoub O, Main JPL, Malan JA, Malgas RD, Manley JR, Maree MDJ, Merry B, Millenaar R, Mnyandu N, Moeng IPT, Monama TE, Mphego MC, New WS, Ngcebetsha B, Oozeer N, Otto AJ, Passmoor SS, Patel AA, Peens-Hough A, Perkins SJ, Ratcliffe SM, Renil R, Rust A, Salie S, Schwardt LC, Serylak M, Siebrits R, Sirothia SK, Smirnov OM, Sofeya L, Swart PS, Tasse C, Taylor DT, Theron IP, Thorat K, Tiplady AJ, Tshongweni S, van Balla TJ, van der Byl A, van der Merwe C, van Dyk CL, Van Rooyen R, Van Tonder V, Van Wyk R, Wallace BH, Welz MG, Williams LP.

Nature. 2019 Sep;573(7773):235-237. doi: 10.1038/s41586-019-1532-5. Epub 2019 Sep 11.

PMID:
31511683
2.

MCL1 and DEDD Promote Urothelial Carcinoma Progression.

Hong AL, Guerriero JL, Doshi MB, Kynnap BD, Kim WJ, Schinzel AC, Modiste R, Schlauch AJ, Adam RM, Kwiatkowski DJ, Beroukhim R, Letai A, Rosenberg JE, Hahn WC.

Mol Cancer Res. 2019 Jun;17(6):1294-1304. doi: 10.1158/1541-7786.MCR-18-0963. Epub 2019 Feb 18.

PMID:
30777879
3.

Concordant miRNA and mRNA expression profiles in humans and mice with bladder outlet obstruction.

Gheinani AH, Köck I, Vasquez E, Baumgartner U, Bigger-Allen A, Sack BS, Burkhard FC, Adam RM, Monastyrskaya K.

Am J Clin Exp Urol. 2018 Dec 20;6(6):219-233. eCollection 2018.

4.

Genome-wide CRISPR screens for Shiga toxins and ricin reveal Golgi proteins critical for glycosylation.

Tian S, Muneeruddin K, Choi MY, Tao L, Bhuiyan RH, Ohmi Y, Furukawa K, Furukawa K, Boland S, Shaffer SA, Adam RM, Dong M.

PLoS Biol. 2018 Nov 27;16(11):e2006951. doi: 10.1371/journal.pbio.2006951. eCollection 2018 Nov.

5.

Immunology, Immunotherapy, and Translating Basic Science into the Clinic for Bladder Cancer.

Ingersoll MA, Li X, Inman BA, Greiner JW, Black PC, Adam RM.

Bladder Cancer. 2018 Oct 29;4(4):429-440. doi: 10.3233/BLC-180175.

6.

Inosine - a Multifunctional Treatment for Complications of Neurologic Injury.

Doyle C, Cristofaro V, Sullivan MP, Adam RM.

Cell Physiol Biochem. 2018;49(6):2293-2303. doi: 10.1159/000493831. Epub 2018 Sep 27. Review.

7.

Heparin-Binding Epidermal Growth Factor-Like Growth Factor as a Critical Mediator of Tissue Repair and Regeneration.

Dao DT, Anez-Bustillos L, Adam RM, Puder M, Bielenberg DR.

Am J Pathol. 2018 Nov;188(11):2446-2456. doi: 10.1016/j.ajpath.2018.07.016. Epub 2018 Aug 22. Review.

8.

The role of the mucosa in modulation of evoked responses in the spinal cord injured rat bladder.

Doyle C, Cristofaro V, Sack BS, Mahmood F, Sullivan MP, Adam RM.

Neurourol Urodyn. 2018 Jun;37(5):1583-1593. doi: 10.1002/nau.23512. Epub 2018 Feb 10.

9.

The Cytotoxicity and Genotoxicity of Particulate and Soluble Cobalt in Human Urothelial Cells.

Speer RM, The T, Xie H, Liou L, Adam RM, Wise JP Sr.

Biol Trace Elem Res. 2017 Nov;180(1):48-55. doi: 10.1007/s12011-017-0989-z. Epub 2017 Mar 21.

PMID:
28324276
10.

Inosine attenuates spontaneous activity in the rat neurogenic bladder through an A2B pathway.

Doyle C, Cristofaro V, Sack BS, Lukianov SN, Schäfer M, Chung YG, Sullivan MP, Adam RM.

Sci Rep. 2017 Mar 15;7:44416. doi: 10.1038/srep44416.

11.

MYC Mediates Large Oncosome-Induced Fibroblast Reprogramming in Prostate Cancer.

Minciacchi VR, Spinelli C, Reis-Sobreiro M, Cavallini L, You S, Zandian M, Li X, Mishra R, Chiarugi P, Adam RM, Posadas EM, Viglietto G, Freeman MR, Cocucci E, Bhowmick NA, Di Vizio D.

Cancer Res. 2017 May 1;77(9):2306-2317. doi: 10.1158/0008-5472.CAN-16-2942. Epub 2017 Feb 15. Erratum in: Cancer Res. 2017 Jul 15;77(14 ):3961.

12.

Deletion of neuropilin 2 enhances detrusor contractility following bladder outlet obstruction.

Vasquez E, Cristofaro V, Lukianov S, Burkhard FC, Gheinani AH, Monastyrskaya K, Bielenberg DR, Sullivan MP, Adam RM.

JCI Insight. 2017 Feb 9;2(3):e90617. doi: 10.1172/jci.insight.90617.

13.

Inflammation and Lymphedema Are Exacerbated and Prolonged by Neuropilin 2 Deficiency.

Mucka P, Levonyak N, Geretti E, Zwaans BMM, Li X, Adini I, Klagsbrun M, Adam RM, Bielenberg DR.

Am J Pathol. 2016 Nov;186(11):2803-2812. doi: 10.1016/j.ajpath.2016.07.022. Epub 2016 Oct 14.

14.

Hexavalent chromium induces chromosome instability in human urothelial cells.

Wise SS, Holmes AL, Liou L, Adam RM, Wise JP Sr.

Toxicol Appl Pharmacol. 2016 Apr 1;296:54-60. doi: 10.1016/j.taap.2016.02.015. Epub 2016 Feb 18.

15.

Inosine Improves Neurogenic Detrusor Overactivity following Spinal Cord Injury.

Chung YG, Seth A, Doyle C, Franck D, Kim D, Cristofaro V, Benowitz LI, Tu DD, Estrada CR, Mauney JR, Sullivan MP, Adam RM.

PLoS One. 2015 Nov 3;10(11):e0141492. doi: 10.1371/journal.pone.0141492. eCollection 2015.

16.

Molecular mechanisms of squamous differentiation in urothelial cell carcinoma: a paradigm for molecular subtyping of urothelial cell carcinoma of the bladder.

Adam RM, DeGraff DJ.

Urol Oncol. 2015 Oct;33(10):444-50. doi: 10.1016/j.urolonc.2015.06.006. Epub 2015 Aug 5. Review.

PMID:
26254697
17.

Mutations in TBX18 Cause Dominant Urinary Tract Malformations via Transcriptional Dysregulation of Ureter Development.

Vivante A, Kleppa MJ, Schulz J, Kohl S, Sharma A, Chen J, Shril S, Hwang DY, Weiss AC, Kaminski MM, Shukrun R, Kemper MJ, Lehnhardt A, Beetz R, Sanna-Cherchi S, Verbitsky M, Gharavi AG, Stuart HM, Feather SA, Goodship JA, Goodship TH, Woolf AS, Westra SJ, Doody DP, Bauer SB, Lee RS, Adam RM, Lu W, Reutter HM, Kehinde EO, Mancini EJ, Lifton RP, Tasic V, Lienkamp SS, Jüppner H, Kispert A, Hildebrandt F.

Am J Hum Genet. 2015 Aug 6;97(2):291-301. doi: 10.1016/j.ajhg.2015.07.001. Epub 2015 Jul 30.

18.

Regulation of microtubule dynamics by DIAPH3 influences amoeboid tumor cell mechanics and sensitivity to taxanes.

Morley S, You S, Pollan S, Choi J, Zhou B, Hager MH, Steadman K, Spinelli C, Rajendran K, Gertych A, Kim J, Adam RM, Yang W, Krishnan R, Knudsen BS, Di Vizio D, Freeman MR.

Sci Rep. 2015 Jul 16;5:12136. doi: 10.1038/srep12136.

19.

Platelet Derived Growth Factor Has a Role in Pressure Induced Bladder Smooth Muscle Cell Hyperplasia and Acts in a Paracrine Way.

Preis L, Herlemann A, Adam RM, Dietz HG, Kappler R, Stehr M.

J Urol. 2015 Dec;194(6):1797-805. doi: 10.1016/j.juro.2015.05.092. Epub 2015 Jun 6.

PMID:
26055827
20.

Dynamic reciprocity in cell-scaffold interactions.

Mauney JR, Adam RM.

Adv Drug Deliv Rev. 2015 Mar;82-83:77-85. doi: 10.1016/j.addr.2014.10.016. Epub 2014 Oct 23. Review.

21.

Pathophysiology and animal modeling of underactive bladder.

Tyagi P, Smith PP, Kuchel GA, de Groat WC, Birder LA, Chermansky CJ, Adam RM, Tse V, Chancellor MB, Yoshimura N.

Int Urol Nephrol. 2014 Sep;46 Suppl 1:S11-21. doi: 10.1007/s11255-014-0808-9. Epub 2014 Sep 20. Review.

22.

Integration of proteomic and transcriptomic profiles identifies a novel PDGF-MYC network in human smooth muscle cells.

Yang W, Ramachandran A, You S, Jeong H, Morley S, Mulone MD, Logvinenko T, Kim J, Hwang D, Freeman MR, Adam RM.

Cell Commun Signal. 2014 Aug 1;12:44. doi: 10.1186/s12964-014-0044-z.

23.

Progress made in the use of animal models for the study of high-risk, nonmuscle invasive bladder cancer.

Lin-Tsai O, Taylor JA 3rd, Clark PE, Adam RM, Wu XR, DeGraff DJ.

Curr Opin Urol. 2014 Sep;24(5):512-6. doi: 10.1097/MOU.0000000000000087. Review.

PMID:
24921908
24.

The use of bi-layer silk fibroin scaffolds and small intestinal submucosa matrices to support bladder tissue regeneration in a rat model of spinal cord injury.

Chung YG, Algarrahi K, Franck D, Tu DD, Adam RM, Kaplan DL, Estrada CR Jr, Mauney JR.

Biomaterials. 2014 Aug;35(26):7452-9. doi: 10.1016/j.biomaterials.2014.05.044. Epub 2014 Jun 7.

25.

Acellular bi-layer silk fibroin scaffolds support tissue regeneration in a rabbit model of onlay urethroplasty.

Chung YG, Tu D, Franck D, Gil ES, Algarrahi K, Adam RM, Kaplan DL, Estrada CR Jr, Mauney JR.

PLoS One. 2014 Mar 14;9(3):e91592. doi: 10.1371/journal.pone.0091592. eCollection 2014.

26.

Bladder tissue regeneration using acellular bi-layer silk scaffolds in a large animal model of augmentation cystoplasty.

Tu DD, Chung YG, Gil ES, Seth A, Franck D, Cristofaro V, Sullivan MP, Di Vizio D, Gomez P 3rd, Adam RM, Kaplan DL, Estrada CR Jr, Mauney JR.

Biomaterials. 2013 Nov;34(34):8681-9. doi: 10.1016/j.biomaterials.2013.08.001. Epub 2013 Aug 13. Erratum in: Biomaterials. 2014 Sep;35(28):8284-5.

27.

Scaffold attachment factor B1 regulates the androgen receptor in concert with the growth inhibitory kinase MST1 and the methyltransferase EZH2.

Mukhopadhyay NK, Kim J, You S, Morello M, Hager MH, Huang WC, Ramachandran A, Yang J, Cinar B, Rubin MA, Adam RM, Oesterreich S, Di Vizio D, Freeman MR.

Oncogene. 2014 Jun 19;33(25):3235-45. doi: 10.1038/onc.2013.294. Epub 2013 Jul 29.

28.

Loss of Sh3gl2/endophilin A1 is a common event in urothelial carcinoma that promotes malignant behavior.

Majumdar S, Gong EM, Di Vizio D, Dreyfuss J, Degraff DJ, Hager MH, Park PJ, Bellmunt J, Matusik RJ, Rosenberg JE, Adam RM.

Neoplasia. 2013 Jul;15(7):749-60.

29.

Loss of caveolin-1 in prostate cancer stroma correlates with reduced relapse-free survival and is functionally relevant to tumour progression.

Ayala G, Morello M, Frolov A, You S, Li R, Rosati F, Bartolucci G, Danza G, Adam RM, Thompson TC, Lisanti MP, Freeman MR, Vizio DD.

J Pathol. 2013 Sep;231(1):77-87. doi: 10.1002/path.4217. Epub 2013 Jul 8.

30.

The impact of discrete modes of spinal cord injury on bladder muscle contractility.

Seth A, Chung YG, Kim D, Ramachandran A, Cristofaro V, Gomez P 3rd, Tu D, Huang L, Benowitz LI, Di Vizio D, Sullivan MP, Adam RM.

BMC Urol. 2013 May 13;13:24. doi: 10.1186/1471-2490-13-24.

31.

The performance of silk scaffolds in a rat model of augmentation cystoplasty.

Seth A, Chung YG, Gil ES, Tu D, Franck D, Di Vizio D, Adam RM, Kaplan DL, Estrada CR Jr, Mauney JR.

Biomaterials. 2013 Jul;34(20):4758-65. doi: 10.1016/j.biomaterials.2013.03.038. Epub 2013 Mar 29.

32.

Evaluation of silk biomaterials in combination with extracellular matrix coatings for bladder tissue engineering with primary and pluripotent cells.

Franck D, Gil ES, Adam RM, Kaplan DL, Chung YG, Estrada CR Jr, Mauney JR.

PLoS One. 2013;8(2):e56237. doi: 10.1371/journal.pone.0056237. Epub 2013 Feb 7.

33.

JunB mediates basal- and TGFβ1-induced smooth muscle cell contractility.

Ramachandran A, Gangopadhyay SS, Krishnan R, Ranpura SA, Rajendran K, Ram-Mohan S, Mulone M, Gong EM, Adam RM.

PLoS One. 2013;8(1):e53430. doi: 10.1371/journal.pone.0053430. Epub 2013 Jan 4.

34.

Large oncosomes in human prostate cancer tissues and in the circulation of mice with metastatic disease.

Di Vizio D, Morello M, Dudley AC, Schow PW, Adam RM, Morley S, Mulholland D, Rotinen M, Hager MH, Insabato L, Moses MA, Demichelis F, Lisanti MP, Wu H, Klagsbrun M, Bhowmick NA, Rubin MA, D'Souza-Schorey C, Freeman MR.

Am J Pathol. 2012 Nov;181(5):1573-84. doi: 10.1016/j.ajpath.2012.07.030. Epub 2012 Sep 27.

35.

Inhibition of TNF-α improves the bladder dysfunction that is associated with type 2 diabetes.

Wang Z, Cheng Z, Cristofaro V, Li J, Xiao X, Gomez P, Ge R, Gong E, Strle K, Sullivan MP, Adam RM, White MF, Olumi AF.

Diabetes. 2012 Aug;61(8):2134-45. doi: 10.2337/db11-1763. Epub 2012 Jun 11.

36.

Increased smooth muscle contractility in mice deficient for neuropilin 2.

Bielenberg DR, Seth A, Shimizu A, Pelton K, Cristofaro V, Ramachandran A, Zwaans BM, Chen C, Krishnan R, Seth M, Huang L, Takashima S, Klagsbrun M, Sullivan MP, Adam RM.

Am J Pathol. 2012 Aug;181(2):548-59. doi: 10.1016/j.ajpath.2012.04.013. Epub 2012 Jun 9.

37.

DIAPH3 governs the cellular transition to the amoeboid tumour phenotype.

Hager MH, Morley S, Bielenberg DR, Gao S, Morello M, Holcomb IN, Liu W, Mouneimne G, Demichelis F, Kim J, Solomon KR, Adam RM, Isaacs WB, Higgs HN, Vessella RL, Di Vizio D, Freeman MR.

EMBO Mol Med. 2012 Aug;4(8):743-60. doi: 10.1002/emmm.201200242. Epub 2012 May 16.

38.

On the (C)USP(2a) of new targets for bladder cancer therapy?

Adam RM.

Cell Cycle. 2012 Apr 1;11(7):1270-1. doi: 10.4161/cc.19904. Epub 2012 Apr 1. No abstract available.

PMID:
22426418
39.

FosB regulates stretch-induced expression of extracellular matrix proteins in smooth muscle.

Ramachandran A, Gong EM, Pelton K, Ranpura SA, Mulone M, Seth A, Gomez P 3rd, Adam RM.

Am J Pathol. 2011 Dec;179(6):2977-89. doi: 10.1016/j.ajpath.2011.08.034. Epub 2011 Oct 11.

40.

When urothelial differentiation pathways go wrong: implications for bladder cancer development and progression.

DeGraff DJ, Cates JM, Mauney JR, Clark PE, Matusik RJ, Adam RM.

Urol Oncol. 2013 Aug;31(6):802-11. doi: 10.1016/j.urolonc.2011.07.017. Epub 2011 Sep 15. Review.

41.

The effect of manipulation of silk scaffold fabrication parameters on matrix performance in a murine model of bladder augmentation.

Gomez P 3rd, Gil ES, Lovett ML, Rockwood DN, Di Vizio D, Kaplan DL, Adam RM, Estrada CR Jr, Mauney JR.

Biomaterials. 2011 Oct;32(30):7562-70. doi: 10.1016/j.biomaterials.2011.06.067. Epub 2011 Jul 20.

42.

A Tbx1-Six1/Eya1-Fgf8 genetic pathway controls mammalian cardiovascular and craniofacial morphogenesis.

Guo C, Sun Y, Zhou B, Adam RM, Li X, Pu WT, Morrow BE, Moon A, Li X.

J Clin Invest. 2011 Apr;121(4):1585-95. doi: 10.1172/JCI44630. Erratum in: J Clin Invest. 2011 May 2;121(5):2060.

43.

An hTERT-immortalized human urothelial cell line that responds to anti-proliferative factor.

Kim J, Ji M, DiDonato JA, Rackley RR, Kuang M, Sadhukhan PC, Mauney JR, Keay SK, Freeman MR, Liou LS, Adam RM.

In Vitro Cell Dev Biol Anim. 2011 Jan;47(1):2-9. doi: 10.1007/s11626-010-9350-y. Epub 2010 Dec 7.

44.

Evaluation of gel spun silk-based biomaterials in a murine model of bladder augmentation.

Mauney JR, Cannon GM, Lovett ML, Gong EM, Di Vizio D, Gomez P 3rd, Kaplan DL, Adam RM, Estrada CR Jr.

Biomaterials. 2011 Jan;32(3):808-18. doi: 10.1016/j.biomaterials.2010.09.051. Epub 2010 Oct 15.

45.

Fluidization and resolidification of the human bladder smooth muscle cell in response to transient stretch.

Chen C, Krishnan R, Zhou E, Ramachandran A, Tambe D, Rajendran K, Adam RM, Deng L, Fredberg JJ.

PLoS One. 2010 Aug 6;5(8):e12035. doi: 10.1371/journal.pone.0012035.

46.

All-trans retinoic acid directs urothelial specification of murine embryonic stem cells via GATA4/6 signaling mechanisms.

Mauney JR, Ramachandran A, Yu RN, Daley GQ, Adam RM, Estrada CR.

PLoS One. 2010 Jul 13;5(7):e11513. doi: 10.1371/journal.pone.0011513.

47.

An Akt- and Fra-1-dependent pathway mediates platelet-derived growth factor-induced expression of thrombomodulin, a novel regulator of smooth muscle cell migration.

Ramachandran A, Ranpura SA, Gong EM, Mulone M, Cannon GM Jr, Adam RM.

Am J Pathol. 2010 Jul;177(1):119-31. doi: 10.2353/ajpath.2010.090772. Epub 2010 May 14.

48.

Histone deacetylase inhibitors and bladder cancer.

Adam RM.

J Urol. 2010 Jun;183(6):2120-1. doi: 10.1016/j.juro.2010.03.047. No abstract available.

PMID:
20399456
49.

Oncosome formation in prostate cancer: association with a region of frequent chromosomal deletion in metastatic disease.

Di Vizio D, Kim J, Hager MH, Morello M, Yang W, Lafargue CJ, True LD, Rubin MA, Adam RM, Beroukhim R, Demichelis F, Freeman MR.

Cancer Res. 2009 Jul 1;69(13):5601-9. doi: 10.1158/0008-5472.CAN-08-3860. Epub 2009 Jun 23.

50.

Heterogeneous nuclear ribonucleoprotein K is a novel regulator of androgen receptor translation.

Mukhopadhyay NK, Kim J, Cinar B, Ramachandran A, Hager MH, Di Vizio D, Adam RM, Rubin MA, Raychaudhuri P, De Benedetti A, Freeman MR.

Cancer Res. 2009 Mar 15;69(6):2210-8. doi: 10.1158/0008-5472.CAN-08-2308. Epub 2009 Mar 3.

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