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Items: 1 to 50 of 73

1.

Phase 3 results for vosaroxin/cytarabine in the subset of patients ≥60 years old with refractory/early relapsed acute myeloid leukemia.

Ravandi F, Ritchie EK, Sayar H, Lancet JE, Craig MD, Vey N, Strickland SA, Schiller GJ, Jabbour E, Pigneux A, Horst HA, Récher C, Klimek VM, Cortes JE, Carella AM, Egyed M, Krug U, Fox JA, Craig AR, Ward R, Smith JA, Acton G, Kantarjian HM, Stuart RK.

Haematologica. 2018 May 24. pii: haematol.2018.191361. doi: 10.3324/haematol.2018.191361. [Epub ahead of print] No abstract available.

2.

A phase I/II trial of AT9283, a selective inhibitor of aurora kinase in children with relapsed or refractory acute leukemia: challenges to run early phase clinical trials for children with leukemia.

Vormoor B, Veal GJ, Griffin MJ, Boddy AV, Irving J, Minto L, Case M, Banerji U, Swales KE, Tall JR, Moore AS, Toguchi M, Acton G, Dyer K, Schwab C, Harrison CJ, Grainger JD, Lancaster D, Kearns P, Hargrave D, Vormoor J.

Pediatr Blood Cancer. 2017 Jun;64(6). doi: 10.1002/pbc.26351. Epub 2016 Dec 1.

PMID:
27905678
3.

Trends in the characteristics, dose-limiting toxicities and efficacy of phase I oncology trials: The Cancer Research UK experience.

Wong HH, Barton C, Acton G, McLeod R, Halford S.

Eur J Cancer. 2016 Oct;66:9-16. doi: 10.1016/j.ejca.2016.07.004. Epub 2016 Aug 8. Review.

PMID:
27514008
4.

Phase 2 multicentre trial investigating intermittent and continuous dosing schedules of the poly(ADP-ribose) polymerase inhibitor rucaparib in germline BRCA mutation carriers with advanced ovarian and breast cancer.

Drew Y, Ledermann J, Hall G, Rea D, Glasspool R, Highley M, Jayson G, Sludden J, Murray J, Jamieson D, Halford S, Acton G, Backholer Z, Mangano R, Boddy A, Curtin N, Plummer R.

Br J Cancer. 2016 Jun 14;114(12):e21. doi: 10.1038/bjc.2016.133. Epub 2016 May 26. No abstract available.

5.

Phase 2 multicentre trial investigating intermittent and continuous dosing schedules of the poly(ADP-ribose) polymerase inhibitor rucaparib in germline BRCA mutation carriers with advanced ovarian and breast cancer.

Drew Y, Ledermann J, Hall G, Rea D, Glasspool R, Highley M, Jayson G, Sludden J, Murray J, Jamieson D, Halford S, Acton G, Backholer Z, Mangano R, Boddy A, Curtin N, Plummer R.

Br J Cancer. 2016 Mar 29;114(7):723-30. doi: 10.1038/bjc.2016.41. Epub 2016 Mar 22. Erratum in: Br J Cancer. 2016 Jun 14;114(12):e21.

6.

Antarctic ice sheet sensitivity to atmospheric CO2 variations in the early to mid-Miocene.

Levy R, Harwood D, Florindo F, Sangiorgi F, Tripati R, von Eynatten H, Gasson E, Kuhn G, Tripati A, DeConto R, Fielding C, Field B, Golledge N, McKay R, Naish T, Olney M, Pollard D, Schouten S, Talarico F, Warny S, Willmott V, Acton G, Panter K, Paulsen T, Taviani M; SMS Science Team.

Proc Natl Acad Sci U S A. 2016 Mar 29;113(13):3453-8. doi: 10.1073/pnas.1516030113. Epub 2016 Feb 22.

7.

Statistical Considerations in Clinical Trial Design of Immunotherapeutic Cancer Agents.

Dranitsaris G, Cohen RB, Acton G, Keltner L, Price M, Amir E, Podack ER, Schreiber TH.

J Immunother. 2015 Sep;38(7):259-66. doi: 10.1097/CJI.0000000000000089.

PMID:
26261889
8.

Vosaroxin plus cytarabine versus placebo plus cytarabine in patients with first relapsed or refractory acute myeloid leukaemia (VALOR): a randomised, controlled, double-blind, multinational, phase 3 study.

Ravandi F, Ritchie EK, Sayar H, Lancet JE, Craig MD, Vey N, Strickland SA, Schiller GJ, Jabbour E, Erba HP, Pigneux A, Horst HA, Recher C, Klimek VM, Cortes J, Roboz GJ, Odenike O, Thomas X, Havelange V, Maertens J, Derigs HG, Heuser M, Damon L, Powell BL, Gaidano G, Carella AM, Wei A, Hogge D, Craig AR, Fox JA, Ward R, Smith JA, Acton G, Mehta C, Stuart RK, Kantarjian HM.

Lancet Oncol. 2015 Sep;16(9):1025-1036. doi: 10.1016/S1470-2045(15)00201-6. Epub 2015 Jul 30.

9.

A phase I trial of AT9283 (a selective inhibitor of aurora kinases) in children and adolescents with solid tumors: a Cancer Research UK study.

Moreno L, Marshall LV, Pearson AD, Morland B, Elliott M, Campbell-Hewson Q, Makin G, Halford SE, Acton G, Ross P, Kazmi-Stokes S, Lock V, Rodriguez A, Lyons JF, Boddy AV, Griffin MJ, Yule M, Hargrave D.

Clin Cancer Res. 2015 Jan 15;21(2):267-73. doi: 10.1158/1078-0432.CCR-14-1592. Epub 2014 Nov 4.

10.

Paleoceanography. Onset of Mediterranean outflow into the North Atlantic.

Hernández-Molina FJ, Stow DA, Alvarez-Zarikian CA, Acton G, Bahr A, Balestra B, Ducassou E, Flood R, Flores JA, Furota S, Grunert P, Hodell D, Jimenez-Espejo F, Kim JK, Krissek L, Kuroda J, Li B, Llave E, Lofi J, Lourens L, Miller M, Nanayama F, Nishida N, Richter C, Roque C, Pereira H, Sanchez Goñi MF, Sierro FJ, Singh AD, Sloss C, Takashimizu Y, Tzanova A, Voelker A, Williams T, Xuan C.

Science. 2014 Jun 13;344(6189):1244-50. doi: 10.1126/science.1251306.

11.

Older Hispanic women, health literacy, and cervical cancer screening.

Flores BE, Acton GJ.

Clin Nurs Res. 2013 Nov;22(4):402-15. doi: 10.1177/1054773813489309. Epub 2013 May 30. Review.

PMID:
23729023
12.

Emotion work in family caregiving for persons with dementia.

Simpson C, Acton G.

Issues Ment Health Nurs. 2013 Jan;34(1):52-8. doi: 10.3109/01612840.2012.720649.

PMID:
23301570
13.

A Cenozoic record of the equatorial Pacific carbonate compensation depth.

Pälike H, Lyle MW, Nishi H, Raffi I, Ridgwell A, Gamage K, Klaus A, Acton G, Anderson L, Backman J, Baldauf J, Beltran C, Bohaty SM, Bown P, Busch W, Channell JE, Chun CO, Delaney M, Dewangan P, Dunkley Jones T, Edgar KM, Evans H, Fitch P, Foster GL, Gussone N, Hasegawa H, Hathorne EC, Hayashi H, Herrle JO, Holbourn A, Hovan S, Hyeong K, Iijima K, Ito T, Kamikuri S, Kimoto K, Kuroda J, Leon-Rodriguez L, Malinverno A, Moore TC Jr, Murphy BH, Murphy DP, Nakamura H, Ogane K, Ohneiser C, Richter C, Robinson R, Rohling EJ, Romero O, Sawada K, Scher H, Schneider L, Sluijs A, Takata H, Tian J, Tsujimoto A, Wade BS, Westerhold T, Wilkens R, Williams T, Wilson PA, Yamamoto Y, Yamamoto S, Yamazaki T, Zeebe RE.

Nature. 2012 Aug 30;488(7413):609-14. doi: 10.1038/nature11360.

PMID:
22932385
14.

From academic solos to industrial symphonies.

Acton G, Gómez-Yafal A, Walsh E.

Nat Biotechnol. 2012 Jul 10;30(7):585-7. doi: 10.1038/nbt.2245. No abstract available.

PMID:
22781674
15.

Molecular dynamics simulations to provide new insights into the asymmetrical ammonium ion movement inside of the [d(G3T4G4)]2 G-quadruplex DNA structure.

Akhshi P, Acton G, Wu G.

J Phys Chem B. 2012 Aug 9;116(31):9363-70. doi: 10.1021/jp304760k. Epub 2012 Jul 25.

PMID:
22780684
16.

Randomized phase II trial of letrozole plus anti-MUC1 antibody AS1402 in hormone receptor-positive locally advanced or metastatic breast cancer.

Ibrahim NK, Yariz KO, Bondarenko I, Manikhas A, Semiglazov V, Alyasova A, Komisarenko V, Shparyk Y, Murray JL, Jones D, Senderovich S, Chau A, Erlandsson F, Acton G, Pegram M.

Clin Cancer Res. 2011 Nov 1;17(21):6822-30. doi: 10.1158/1078-0432.CCR-11-1151. Epub 2011 Aug 30.

17.

A phase 1 study of AS1409, a novel antibody-cytokine fusion protein, in patients with malignant melanoma or renal cell carcinoma.

Rudman SM, Jameson MB, McKeage MJ, Savage P, Jodrell DI, Harries M, Acton G, Erlandsson F, Spicer JF.

Clin Cancer Res. 2011 Apr 1;17(7):1998-2005. doi: 10.1158/1078-0432.CCR-10-2490. Epub 2011 Mar 29.

18.

Relationships among nutritional self-efficacy, health locus of control and nutritional status in older Taiwanese adults.

Chen SH, Acton G, Shao JH.

J Clin Nurs. 2010 Aug;19(15-16):2117-27. doi: 10.1111/j.1365-2702.2009.03186.x.

PMID:
20659192
19.

Transient retinal effects of 5,6-dimethylxanthenone-4-acetic acid (DMXAA, ASA404), an antitumor vascular-disrupting agent in phase I clinical trials.

Jameson MB, Sharp DM, Sissingh JI, Hogg CR, Thompson PI, McKeage MJ, Jeffery M, Waller S, Acton G, Green C, Baguley BC.

Invest Ophthalmol Vis Sci. 2009 Jun;50(6):2553-9. doi: 10.1167/iovs.08-2068. Epub 2009 Apr 22.

PMID:
19387077
20.

Ways to maintain independence among Taiwanese elderly adults with hip fractures: a qualitative study.

Huang TT, Acton GJ.

Geriatr Nurs. 2009 Jan-Feb;30(1):28-35. doi: 10.1016/j.gerinurse.2008.03.006. Epub 2008 Nov 17.

PMID:
19215810
21.

Differential item functioning of the English and Chinese versions of the Fagerstrom Test for Nicotine Dependence.

Yamada H, Acton GS, Tsoh JY.

Addict Behav. 2009 Feb;34(2):125-33. doi: 10.1016/j.addbeh.2008.09.003. Epub 2008 Sep 17.

PMID:
18929444
22.

Increasing social communication in persons with dementia.

Acton GJ, Yauk S, Hopkins BA, Mayhew PA.

Res Theory Nurs Pract. 2007;21(1):32-44.

PMID:
17378463
23.

Conceptualization and psychometric properties of the Caregiver Burden Scale in Taiwan.

Kao HF, Acton GJ.

Issues Ment Health Nurs. 2006 Oct;27(8):853-66.

PMID:
16938788
24.

Drilling to gabbro in intact ocean crust.

Wilson DS, Teagle DA, Alt JC, Banerjee NR, Umino S, Miyashita S, Acton GD, Anma R, Barr SR, Belghoul A, Carlut J, Christie DM, Coggon RM, Cooper KM, Cordier C, Crispini L, Durand SR, Einaudi F, Galli L, Gao Y, Geldmacher J, Gilbert LA, Hayman NW, Herrero-Bervera E, Hirano N, Holter S, Ingle S, Jiang S, Kalberkamp U, Kerneklian M, Koepke J, Laverne C, Vasquez HL, Maclennan J, Morgan S, Neo N, Nichols HJ, Park SH, Reichow MK, Sakuyama T, Sano T, Sandwell R, Scheibner B, Smith-Duque CE, Swift SA, Tartarotti P, Tikku AA, Tominaga M, Veloso EA, Yamasaki T, Yamazaki S, Ziegler C.

Science. 2006 May 19;312(5776):1016-20. Epub 2006 Apr 20.

25.
26.

Health promotion research: addressing the needs of older adults and their caregivers.

Acton GJ, Carter PA.

J Gerontol Nurs. 2006 Feb;32(2):5. No abstract available.

PMID:
16502755
27.

Helping family members manage medication administration hassles.

Travis SS, Kao HF, Acton GJ.

J Psychosoc Nurs Ment Health Serv. 2005 Nov;43(11):13-5.

PMID:
16350907
28.
29.

A conceptual and psychometric framework for distinguishing categories and dimensions.

De Boeck P, Wilson M, Acton GS.

Psychol Rev. 2005 Jan;112(1):129-58.

PMID:
15631591
30.
31.

Are there sex differences in emotional and biological responses in spousal caregivers of patients with Alzheimer's disease?

Thompson RL, Lewis SL, Murphy MR, Hale JM, Blackwell PH, Acton GJ, Clough DH, Patrick GJ, Bonner PN.

Biol Res Nurs. 2004 Apr;5(4):319-30.

PMID:
15068661
32.

Relocation to a long-term care facility: working with patients and families before, during, and after.

Kao HF, Travis SS, Acton GJ.

J Psychosoc Nurs Ment Health Serv. 2004 Mar;42(3):10-6.

PMID:
15068162
33.

Spirituality in caregivers of family members with dementia.

Acton GJ, Miller EW.

J Holist Nurs. 2003 Jun;21(2):117-30.

PMID:
12794956
34.

A framework for developing a coding scheme for meta-analysis.

Brown SA, Upchurch SL, Acton GJ.

West J Nurs Res. 2003 Mar;25(2):205-22. Review.

PMID:
12666644
35.
36.
37.
38.

Interventions for family members caring for an elder with dementia.

Acton GJ, Winter MA.

Annu Rev Nurs Res. 2002;20:149-79. Review.

PMID:
12092509
39.

The relationship between basic need satisfaction and emotional eating.

Timmerman GM, Acton GJ.

Issues Ment Health Nurs. 2001 Oct-Nov;22(7):691-701.

PMID:
11881182
40.

Self-transcendence and family caregivers of adults with dementia.

Acton GJ, Wright KB.

J Holist Nurs. 2000 Jun;18(2):143-58. Review.

PMID:
11847767
41.

Health-promoting self-care in family caregivers.

Acton GJ.

West J Nurs Res. 2002 Feb;24(1):73-86.

PMID:
11829276
42.

Meta-analysis: a tool for evidence-based practice.

Acton GJ.

AACN Clin Issues. 2001 Nov;12(4):539-45. Review.

PMID:
11759426
43.
44.

Depression and stages of change for smoking in psychiatric outpatients.

Acton GS, Prochaska JJ, Kaplan AS, Small T, Hall SM.

Addict Behav. 2001 Sep-Oct;26(5):621-31.

PMID:
11676374
45.

Communication from individuals with advanced DAT: can it provide clues to their sense of self-awareness and well-being?

Mayhew PA, Acton GJ, Yauk S, Hopkins BA.

Geriatr Nurs. 2001 Mar-Apr;22(2):106-10.

PMID:
11326220
46.

Basic need status and health-promoting self-care behavior in adults.

Acton GJ, Malathum P.

West J Nurs Res. 2000 Nov;22(7):796-811.

PMID:
11077548
47.

The lin-11 LIM domain transcription factor is necessary for morphogenesis of C. elegans uterine cells.

Newman AP, Acton GZ, Hartwieg E, Horvitz HR, Sternberg PW.

Development. 1999 Dec;126(23):5319-26.

48.

Communicating with individuals with dementia. The impaired person's perspective.

Acton GJ, Mayhew PA, Hopkins BA, Yauk S.

J Gerontol Nurs. 1999 Feb;25(2):6-13.

PMID:
10347432
49.
50.

Theory-based nursing practice.

Raudonis BM, Acton GJ.

J Adv Nurs. 1997 Jul;26(1):138-45.

PMID:
9231288

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