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2000 1
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2022 11
2023 12
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Page 1
ACOX3 Dysfunction as a Potential Cause of Recurrent Spontaneous Vasospasm of Internal Carotid Artery.
Kim JT, Won SY, Kang K, Kim SH, Park MS, Choi KH, Nam TS, Denis SW, Ferdinandusse S, Lee JE, Choi SY, Kim MK. Kim JT, et al. Transl Stroke Res. 2020 Oct;11(5):1041-1051. doi: 10.1007/s12975-020-00779-z. Epub 2020 Jan 23. Transl Stroke Res. 2020. PMID: 31975215
The carbachol-induced HASMC contraction was restored by transfection with plasmids encoding siRNA-resistant wild-type ACOX3, but not by transfection with ACOX3 G222E or by co-transfection with ACOX3 F79 V and ACOX3 G222E, indicating that the two ACO …
The carbachol-induced HASMC contraction was restored by transfection with plasmids encoding siRNA-resistant wild-type ACOX3, but not …
Treatment with recombinant Sirt1 rewires the cardiac lipidome and rescues diabetes-related metabolic cardiomyopathy.
Costantino S, Mengozzi A, Velagapudi S, Mohammed SA, Gorica E, Akhmedov A, Mongelli A, Pugliese NR, Masi S, Virdis A, Hülsmeier A, Matter CM, Hornemann T, Melina G, Ruschitzka F, Luscher TF, Paneni F. Costantino S, et al. Cardiovasc Diabetol. 2023 Nov 13;22(1):312. doi: 10.1186/s12933-023-02057-2. Cardiovasc Diabetol. 2023. PMID: 37957697 Free PMC article.
Mechanistically, several genes involved in lipid trafficking, metabolism and inflammation, such as Cd36, Acox3, Pparg, Ncoa3, and Ppara were downregulated by rSirt1 both in vitro and in vivo. ...
Mechanistically, several genes involved in lipid trafficking, metabolism and inflammation, such as Cd36, Acox3, Pparg, Ncoa3, and Ppa …
Proteomic analysis reveals semaglutide impacts lipogenic protein expression in epididymal adipose tissue of obese mice.
Zhu R, Chen S. Zhu R, et al. Front Endocrinol (Lausanne). 2023 Mar 21;14:1095432. doi: 10.3389/fendo.2023.1095432. eCollection 2023. Front Endocrinol (Lausanne). 2023. PMID: 37025414 Free PMC article.
Bioinformatics analysis showed a reduction of CD36, FABP5, ACSL, ACOX3, PLIN2, ANGPTL4, LPL, MGLL, AQP7, and PDK4 involved in the lipid metabolism in the Sema group accompanied by a decrease in visceral fat accumulation, blood lipids, and improvement in glucose intolerance …
Bioinformatics analysis showed a reduction of CD36, FABP5, ACSL, ACOX3, PLIN2, ANGPTL4, LPL, MGLL, AQP7, and PDK4 involved in the lip …
ACOX-driven peroxisomal heterogeneity and functional compartmentalization in brown adipocytes of hypothyroid rats.
Aleksic M, Golic I, Jankovic A, Cvoro A, Korac A. Aleksic M, et al. R Soc Open Sci. 2023 May 3;10(5):230109. doi: 10.1098/rsos.230109. eCollection 2023 May. R Soc Open Sci. 2023. PMID: 37153362 Free PMC article.
Therefore, we used methimazole-induced hypothyroidism to study ACOX1 and ACOX3 protein expression and their tissue immunolocalization. Additionally, we analysed their specific peroxisomal localization and colocalization in parallel with peroxisomal structural compartmental …
Therefore, we used methimazole-induced hypothyroidism to study ACOX1 and ACOX3 protein expression and their tissue immunolocalization …
Regulatory Roles of Peroxisomal Metabolic Pathways Involved in Musk Secretion in Muskrats.
Zhang M, Yang S, Shi M, Zhang S, Zhang T, Li Y, Xu S, Cha M, Meng Y, Lin S, Yu J, Li X, Mu A, Hu D, Liu S. Zhang M, et al. J Membr Biol. 2019 Feb;252(1):61-75. doi: 10.1007/s00232-018-0057-4. Epub 2019 Jan 2. J Membr Biol. 2019. PMID: 30604068

We detected 21 genes in the peroxisomal metabolic pathways, including PEX14(peroxin-14) and ACOX3(acyl-CoA oxidase), which exhibited significant differential expression between the musk-secreting season and the non-secreting season (p < 0.05). ...In addition, we examine

…
We detected 21 genes in the peroxisomal metabolic pathways, including PEX14(peroxin-14) and ACOX3(acyl-CoA oxidase), which exhibited …
A prediction model for prognosis of gastric adenocarcinoma based on six metabolism-related genes.
Zhao J, Liu Y, Cui Q, He R, Zhao JR, Lu L, Wang HQ, Dai H, Wang H, Yang W. Zhao J, et al. Biochem Biophys Rep. 2023 Feb 18;34:101440. doi: 10.1016/j.bbrep.2023.101440. eCollection 2023 Jul. Biochem Biophys Rep. 2023. PMID: 36852096 Free PMC article.
We then extracted MRGs from these DEGs and systematically investigated the prognostic value of these differential MRGs for predicting patients' overall survival by univariable and multivariable Cox regression analysis. Six metabolic genes (ACOX3, APOE, DIO2, HSD17B4, NUAK1 …
We then extracted MRGs from these DEGs and systematically investigated the prognostic value of these differential MRGs for predicting patien …
Acyl-coenzyme A oxidases 1 and 3 in brown trout (Salmo trutta f. fario): Can peroxisomal fatty acid β-oxidation be regulated by estrogen signaling?
Madureira TV, Castro LF, Rocha E. Madureira TV, et al. Fish Physiol Biochem. 2016 Feb;42(1):389-401. doi: 10.1007/s10695-015-0146-6. Epub 2015 Oct 27. Fish Physiol Biochem. 2016. PMID: 26508171
The isolated Acox1 and Acox3 show high levels of sequence conservation compared to those of other teleosts. ...Both isoforms display tissue specificity, with Acox1-3II presenting a more ubiquitous expression in comparison with Acox1-3I. Acox3 was expressed in almost …
The isolated Acox1 and Acox3 show high levels of sequence conservation compared to those of other teleosts. ...Both isoforms display …
Integrated multi-omics analysis reveals variation in intramuscular fat among muscle locations of Qinchuan cattle.
Yu H, Wang J, Zhang K, Cheng G, Mei C, Zan L. Yu H, et al. BMC Genomics. 2023 Jul 1;24(1):367. doi: 10.1186/s12864-023-09452-9. BMC Genomics. 2023. PMID: 37391702 Free PMC article.
The deposition of IMF could be regulated by the metabolic pathway for unsaturated fatty acids involving EA and the ACOX3, HACD2, and SCD5 genes. In addition, differentially expressed genes and metabolites were enriched in three major KEGG pathways: purine metabolism, pyrim …
The deposition of IMF could be regulated by the metabolic pathway for unsaturated fatty acids involving EA and the ACOX3, HACD2, and …
Altered expression of ACOX2 in non-small cell lung cancer.
Sui JSY, Martin P, Keogh A, Murchan P, Ryan L, Nicholson S, Cuffe S, Broin PÓ, Finn SP, Fitzmaurice GJ, Ryan R, Young V, Gray SG. Sui JSY, et al. BMC Pulm Med. 2022 Aug 23;22(1):321. doi: 10.1186/s12890-022-02115-7. BMC Pulm Med. 2022. PMID: 35999530 Free PMC article.
One key family of enzymes in this process are the peroxisomal acyl-CoA oxidases (ACOX1, ACOX2 and ACOX3), the expression of which has been shown to be dysregulated in some cancers. ...
One key family of enzymes in this process are the peroxisomal acyl-CoA oxidases (ACOX1, ACOX2 and ACOX3), the expression of which has …
Waterborne exposure to the antineoplastic 5-fluorouracil alters lipid composition in larval zebrafish (Danio rerio).
Ivantsova E, Henry EE, Konig I, English CD, Souders CL 2nd, Point AD, Simmons DBD, Martyniuk CJ. Ivantsova E, et al. Sci Total Environ. 2024 Apr 10;928:172377. doi: 10.1016/j.scitotenv.2024.172377. Online ahead of print. Sci Total Environ. 2024. PMID: 38604366
We also measured the expression levels of 14 lipid-related enzymes and transporters (e.g., acox3, dgat1, fads2, fasn, elovl2) using real-time PCR; however, mRNA abundance levels were not affected, suggesting transcriptional changes may not be a primary mechanism underlying …
We also measured the expression levels of 14 lipid-related enzymes and transporters (e.g., acox3, dgat1, fads2, fasn, elovl2) using r …
66 results