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Items: 24


A chemical toolbox for the study of bromodomains and epigenetic signaling.

Wu Q, Heidenreich D, Zhou S, Ackloo S, Krämer A, Nakka K, Lima-Fernandes E, Deblois G, Duan S, Vellanki RN, Li F, Vedadi M, Dilworth J, Lupien M, Brennan PE, Arrowsmith CH, Müller S, Fedorov O, Filippakopoulos P, Knapp S.

Nat Commun. 2019 Apr 23;10(1):1915. doi: 10.1038/s41467-019-09672-2.


Design and characterization of mutant and wildtype huntingtin proteins produced from a toolkit of scalable eukaryotic expression systems.

Harding RJ, Loppnau P, Ackloo S, Lemak A, Hutchinson A, Hunt B, Holehouse AS, Ho JC, Fan L, Toledo-Sherman L, Seitova A, Arrowsmith CH.

J Biol Chem. 2019 Apr 26;294(17):6986-7001. doi: 10.1074/jbc.RA118.007204. Epub 2019 Mar 6.


A chemical biology toolbox to study protein methyltransferases and epigenetic signaling.

Scheer S, Ackloo S, Medina TS, Schapira M, Li F, Ward JA, Lewis AM, Northrop JP, Richardson PL, Kaniskan HÜ, Shen Y, Liu J, Smil D, McLeod D, Zepeda-Velazquez CA, Luo M, Jin J, Barsyte-Lovejoy D, Huber KVM, De Carvalho DD, Vedadi M, Zaph C, Brown PJ, Arrowsmith CH.

Nat Commun. 2019 Jan 3;10(1):19. doi: 10.1038/s41467-018-07905-4.


Donated chemical probes for open science.

Müller S, Ackloo S, Arrowsmith CH, Bauser M, Baryza JL, Blagg J, Böttcher J, Bountra C, Brown PJ, Bunnage ME, Carter AJ, Damerell D, Dötsch V, Drewry DH, Edwards AM, Edwards J, Elkins JM, Fischer C, Frye SV, Gollner A, Grimshaw CE, IJzerman A, Hanke T, Hartung IV, Hitchcock S, Howe T, Hughes TV, Laufer S, Li VM, Liras S, Marsden BD, Matsui H, Mathias J, O'Hagan RC, Owen DR, Pande V, Rauh D, Rosenberg SH, Roth BL, Schneider NS, Scholten C, Singh Saikatendu K, Simeonov A, Takizawa M, Tse C, Thompson PR, Treiber DK, Viana AY, Wells CI, Willson TM, Zuercher WJ, Knapp S, Mueller-Fahrnow A.

Elife. 2018 Apr 20;7. pii: e34311. doi: 10.7554/eLife.34311.


Chemical probes targeting epigenetic proteins: Applications beyond oncology.

Ackloo S, Brown PJ, Müller S.

Epigenetics. 2017 May 4;12(5):378-400. doi: 10.1080/15592294.2017.1279371. Epub 2017 Jan 12. Review.


Chemical Biology Approaches for Characterization of Epigenetic Regulators.

Barsyte-Lovejoy D, Szewczyk MM, Prinos P, Lima-Fernandes E, Ackloo S, Arrowsmith CH.

Methods Enzymol. 2016;574:79-103. doi: 10.1016/bs.mie.2016.01.011. Epub 2016 Feb 16.


The day/night proteome in the murine heart.

Podobed P, Pyle WG, Ackloo S, Alibhai FJ, Tsimakouridze EV, Ratcliffe WF, Mackay A, Simpson J, Wright DC, Kirby GM, Young ME, Martino TA.

Am J Physiol Regul Integr Comp Physiol. 2014 Jul 15;307(2):R121-37.


C-Terminal region of teneurin-1 co-localizes with dystroglycan and modulates cytoskeletal organization through an extracellular signal-regulated kinase-dependent stathmin- and filamin A-mediated mechanism in hippocampal cells.

Chand D, Song L, deLannoy L, Barsyte-Lovejoy D, Ackloo S, Boutros PC, Evans K, Belsham DD, Lovejoy DA.

Neuroscience. 2012 Sep 6;219:255-70. doi: 10.1016/j.neuroscience.2012.05.069. Epub 2012 Jun 12.


A phase I study of the metal ionophore clioquinol in patients with advanced hematologic malignancies.

Schimmer AD, Jitkova Y, Gronda M, Wang Z, Brandwein J, Chen C, Gupta V, Schuh A, Yee K, Chen J, Ackloo S, Booth T, Keays S, Minden MD.

Clin Lymphoma Myeloma Leuk. 2012 Oct;12(5):330-6. doi: 10.1016/j.clml.2012.05.005. Epub 2012 Jun 9.


Proteomics analyses of activated human optic nerve head lamina cribrosa cells following biomechanical strain.

Rogers R, Dharsee M, Ackloo S, Flanagan JG.

Invest Ophthalmol Vis Sci. 2012 Jun 20;53(7):3806-16. doi: 10.1167/iovs.11-8480.


Proteomic analyses reveal high expression of decorin and endoplasmin (HSP90B1) are associated with breast cancer metastasis and decreased survival.

Cawthorn TR, Moreno JC, Dharsee M, Tran-Thanh D, Ackloo S, Zhu PH, Sardana G, Chen J, Kupchak P, Jacks LM, Miller NA, Youngson BJ, Iakovlev V, Guidos CJ, Vallis KA, Evans KR, McCready D, Leong WL, Done SJ.

PLoS One. 2012;7(2):e30992. doi: 10.1371/journal.pone.0030992. Epub 2012 Feb 20.


Proteomics analyses of human optic nerve head astrocytes following biomechanical strain.

Rogers RS, Dharsee M, Ackloo S, Sivak JM, Flanagan JG.

Mol Cell Proteomics. 2012 Feb;11(2):M111.012302. doi: 10.1074/mcp.M111.012302. Epub 2011 Nov 29.


Applying mass spectrometry based proteomic technology to advance the understanding of multiple myeloma.

Micallef J, Dharsee M, Chen J, Ackloo S, Evans K, Qiu L, Chang H.

J Hematol Oncol. 2010 Apr 7;3:13. doi: 10.1186/1756-8722-3-13. Review.


Precipitation and selective extraction of human serum endogenous peptides with analysis by quadrupole time-of-flight mass spectrometry reveals posttranslational modifications and low-abundance peptides.

Williams D, Ackloo S, Zhu P, Bowden P, Evans KR, Addison CL, Lock C, Marshall JG.

Anal Bioanal Chem. 2010 Feb;396(3):1223-47. doi: 10.1007/s00216-009-3345-0. Epub 2009 Dec 22.


Endogenous peptides from biophysical and biochemical fractionation of serum analyzed by matrix-assisted laser desorption/ionization and electrospray ionization hybrid quadrupole time-of-flight.

Tucholska M, Scozzaro S, Williams D, Ackloo S, Lock C, Siu KW, Evans KR, Marshall JG.

Anal Biochem. 2007 Nov 15;370(2):228-45. Epub 2007 Aug 8.


Biomarker discovery and analysis platform: application to Alzheimer's disease.

Kuzdzal S, Lopez M, Mikulskis A, Golenko E, DiCesare J, Denoyer E, Patton W, Ediger R, Sapp L, Ziegert T, Ackloo S, Wall MR, Mannion DP, della Cioppa G, Wolfe G, Bennett D, Melov S.

Biotechniques. 2005 Oct;39(4):606-7. No abstract available.


Proteomic analysis of mitochondrial proteins.

Lopez MF, Melov S, Johnson F, Nagulko N, Golenko E, Kuzdzal S, Ackloo S, Mikulskis A.

Int Rev Neurobiol. 2004;61:31-48. Review. No abstract available.


Site of alkylation of N-methyl- and N-ethylaniline in the gas phase: a tandem mass spectrometric study.

Ackloo S, Harrison AG, Terlouw JK.

J Mass Spectrom. 2004 Jun;39(6):647-54.


A high-performance matrix-assisted laser desorption/ionization orthogonal time-of-flight mass spectrometer with collisional cooling.

Loboda AV, Ackloo S, Chernushevich IV.

Rapid Commun Mass Spectrom. 2003;17(22):2508-16.


Analysis of carrageenans by matrix-assisted laser desorption/ionization and electrospray ionization mass spectrometry. I. kappa-Carrageenans.

Ackloo S, Terlouw JK, Ruttink PJ, Burgers PC.

Rapid Commun Mass Spectrom. 2001;15(14):1152-9.


Structural analysis of diols by electrospray mass spectrometry on boric acid complexes.

Ackloo SZ, Burgers PC, McCarry BE, Terlouw JK.

Rapid Commun Mass Spectrom. 1999 Dec 15;13(23):2406-2415.


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