Sort by
Items per page

Send to

Choose Destination

Search results

Items: 30


Patient mutations linked to arrhythmogenic cardiomyopathy enhance calpain-mediated desmoplakin degradation.

Ng R, Manring HR, Papoutsidakis N, Albertelli T, Tsai N, See C, Li X, Park J, Stevens TL, Bobbili PJ, Riaz M, Ren Y, Stoddard CE, Janssen PM, Bunch TJ, Hall SP, Lo YC, Jacoby DL, Qyang Y, Wright N, Ackermann MA, Campbell SG.

JCI Insight. 2019 Jun 13;5. pii: 128643. doi: 10.1172/jci.insight.128643.


Obscurin is a semi-flexible molecule in solution.

Whitley JA, Ex-Willey AM, Marzolf DR, Ackermann MA, Tongen AL, Kokhan O, Wright NT.

Protein Sci. 2019 Apr;28(4):717-726. doi: 10.1002/pro.3578. Epub 2019 Feb 6.


At the heart of inter- and intracellular signaling: the intercalated disc.

Manring HR, Dorn LE, Ex-Willey A, Accornero F, Ackermann MA.

Biophys Rev. 2018 Aug;10(4):961-971. doi: 10.1007/s12551-018-0430-7. Epub 2018 Jun 6. Review.


Corrigendum: The Phosphorylation Profile of Myosin Binding Protein-C Slow is Dynamically Regulated in Slow-Twitch Muscles in Health and Disease.

Ackermann MA, Kerr JP, King B, Ward CW, Kontrogianni-Konstantopoulos A.

Sci Rep. 2018 May 11;8:46969. doi: 10.1038/srep46969.


Correction: Obscurins: Goliaths and Davids Take over Non-Muscle Tissues.

Ackermann MA, Shriver M, Perry NA, Hu LR, Kontrogianni-Konstantopoulos A.

PLoS One. 2018 Jan 3;13(1):e0190842. doi: 10.1371/journal.pone.0190842. eCollection 2018.


TGF-β1 affects cell-cell adhesion in the heart in an NCAM1-dependent mechanism.

Ackermann MA, Petrosino JM, Manring HR, Wright P, Shettigar V, Kilic A, Janssen PML, Ziolo MT, Accornero F.

J Mol Cell Cardiol. 2017 Nov;112:49-57. doi: 10.1016/j.yjmcc.2017.08.015. Epub 2017 Sep 1.


Novel obscurins mediate cardiomyocyte adhesion and size via the PI3K/AKT/mTOR signaling pathway.

Ackermann MA, King B, Lieberman NAP, Bobbili PJ, Rudloff M, Berndsen CE, Wright NT, Hecker PA, Kontrogianni-Konstantopoulos A.

J Mol Cell Cardiol. 2017 Oct;111:27-39. doi: 10.1016/j.yjmcc.2017.08.004. Epub 2017 Aug 4.


Metabolic surgery: gastric bypass for the treatment of type 2 diabetes mellitus.

Quevedo MDP, Palermo M, Serra E, Ackermann MA.

Transl Gastroenterol Hepatol. 2017 Jun 6;2:58. doi: 10.21037/tgh.2017.05.10. eCollection 2017. Review.


Deregulated Ca2+ cycling underlies the development of arrhythmia and heart disease due to mutant obscurin.

Hu LR, Ackermann MA, Hecker PA, Prosser BL, King B, O'Connell KA, Grogan A, Meyer LC, Berndsen CE, Wright NT, Jonathan Lederer W, Kontrogianni-Konstantopoulos A.

Sci Adv. 2017 Jun 7;3(6):e1603081. doi: 10.1126/sciadv.1603081. eCollection 2017 Jun.


Obscure functions: the location-function relationship of obscurins.

Manring HR, Carter OA, Ackermann MA.

Biophys Rev. 2017 Jun;9(3):245-258. doi: 10.1007/s12551-017-0254-x. Epub 2017 Mar 29. Review.


Agreement of tricuspid annular systolic excursion measurement between transthoracic and transesophageal echocardiography in the perioperative setting.

Flo Forner A, Hasheminejad E, Sabate S, Ackermann MA, Turton EW, Ender J.

Int J Cardiovasc Imaging. 2017 Sep;33(9):1385-1394. doi: 10.1007/s10554-017-1128-9. Epub 2017 Apr 13.


Links between mTOR and the immunoproteasome: Therapeutic targets for cardiac hypertrophy?

Ackermann MA.

J Mol Cell Cardiol. 2015 Dec;89(Pt B):113-5. doi: 10.1016/j.yjmcc.2015.09.014. Epub 2015 Sep 25. No abstract available.


Myosin Binding Protein-C Slow Phosphorylation is Altered in Duchenne Dystrophy and Arthrogryposis Myopathy in Fast-Twitch Skeletal Muscles.

Ackermann MA, Ward CW, Gurnett C, Kontrogianni-Konstantopoulos A.

Sci Rep. 2015 Aug 19;5:13235. doi: 10.1038/srep13235.


The Phosphorylation Profile of Myosin Binding Protein-C Slow is Dynamically Regulated in Slow-Twitch Muscles in Health and Disease.

Ackermann MA, Kerr JP, King B, W Ward C, Kontrogianni-Konstantopoulos A.

Sci Rep. 2015 Aug 19;5:12637. doi: 10.1038/srep12637. Erratum in: Sci Rep. 2018 May 11;8:46969.


The sarcomeric M-region: a molecular command center for diverse cellular processes.

Hu LY, Ackermann MA, Kontrogianni-Konstantopoulos A.

Biomed Res Int. 2015;2015:714197. doi: 10.1155/2015/714197. Epub 2015 Apr 15. Review.


Obscurins: Goliaths and Davids take over non-muscle tissues.

Ackermann MA, Shriver M, Perry NA, Hu LY, Kontrogianni-Konstantopoulos A.

PLoS One. 2014 Feb 6;9(2):e88162. doi: 10.1371/journal.pone.0088162. eCollection 2014. Erratum in: PLoS One. 2018 Jan 3;13(1):e0190842.


Myosin binding protein-C slow: a multifaceted family of proteins with a complex expression profile in fast and slow twitch skeletal muscles.

Ackermann MA, Kontrogianni-Konstantopoulos A.

Front Physiol. 2013 Dec 25;4:391. doi: 10.3389/fphys.2013.00391. eCollection 2013.


Loss of actomyosin regulation in distal arthrogryposis myopathy due to mutant myosin binding protein-C slow.

Ackermann MA, Patel PD, Valenti J, Takagi Y, Homsher E, Sellers JR, Kontrogianni-Konstantopoulos A.

FASEB J. 2013 Aug;27(8):3217-28. doi: 10.1096/fj.13-228882. Epub 2013 May 8. Erratum in: FASEB J. 2018 Mar;32(3):1729-1730.


Obscurins: unassuming giants enter the spotlight.

Perry NA, Ackermann MA, Shriver M, Hu LY, Kontrogianni-Konstantopoulos A.

IUBMB Life. 2013 Jun;65(6):479-86. doi: 10.1002/iub.1157. Epub 2013 Mar 20. Review.


Integrity of the network sarcoplasmic reticulum in skeletal muscle requires small ankyrin 1.

Ackermann MA, Ziman AP, Strong J, Zhang Y, Hartford AK, Ward CW, Randall WR, Kontrogianni-Konstantopoulos A, Bloch RJ.

J Cell Sci. 2011 Nov 1;124(Pt 21):3619-30. doi: 10.1242/jcs.085159. Epub 2011 Nov 1.


Myosin binding protein-C: a regulator of actomyosin interaction in striated muscle.

Ackermann MA, Kontrogianni-Konstantopoulos A.

J Biomed Biotechnol. 2011;2011:636403. doi: 10.1155/2011/636403. Epub 2011 Oct 16. Review.


Myosin binding protein-C slow is a novel substrate for protein kinase A (PKA) and C (PKC) in skeletal muscle.

Ackermann MA, Kontrogianni-Konstantopoulos A.

J Proteome Res. 2011 Oct 7;10(10):4547-55. doi: 10.1021/pr200355w. Epub 2011 Sep 22.


Effects of 12-week overground walking training at ventilatory threshold velocity in type 2 diabetic women.

Belli T, Ribeiro LF, Ackermann MA, Baldissera V, Gobatto CA, Galdino da Silva R.

Diabetes Res Clin Pract. 2011 Sep;93(3):337-43. doi: 10.1016/j.diabres.2011.05.007. Epub 2011 Jun 1.


Electrostatic interactions mediate binding of obscurin to small ankyrin 1: biochemical and molecular modeling studies.

Busby B, Oashi T, Willis CD, Ackermann MA, Kontrogianni-Konstantopoulos A, Mackerell AD Jr, Bloch RJ.

J Mol Biol. 2011 Apr 29;408(2):321-34. doi: 10.1016/j.jmb.2011.01.053. Epub 2011 Feb 17.


Characterization and comparison of two binding sites on obscurin for small ankyrin 1.

Busby B, Willis CD, Ackermann MA, Kontrogianni-Konstantopoulos A, Bloch RJ.

Biochemistry. 2010 Nov 23;49(46):9948-56. doi: 10.1021/bi101165p. Epub 2010 Nov 1.


Myosin binding protein-C slow: an intricate subfamily of proteins.

Ackermann MA, Kontrogianni-Konstantopoulos A.

J Biomed Biotechnol. 2010;2010:652065. doi: 10.1155/2010/652065. Epub 2010 Apr 8. Review.


Muscle giants: molecular scaffolds in sarcomerogenesis.

Kontrogianni-Konstantopoulos A, Ackermann MA, Bowman AL, Yap SV, Bloch RJ.

Physiol Rev. 2009 Oct;89(4):1217-67. doi: 10.1152/physrev.00017.2009. Review.


Obscurin interacts with a novel isoform of MyBP-C slow at the periphery of the sarcomeric M-band and regulates thick filament assembly.

Ackermann MA, Hu LY, Bowman AL, Bloch RJ, Kontrogianni-Konstantopoulos A.

Mol Biol Cell. 2009 Jun;20(12):2963-78. doi: 10.1091/mbc.E08-12-1251. Epub 2009 Apr 29.


Lactate and ventilatory thresholds in type 2 diabetic women.

Belli T, Ackermann MA, Ribeiro LF, Langeani R, Galdino da Silva R, Baldissera V.

Diabetes Res Clin Pract. 2007 Apr;76(1):18-23. Epub 2006 Sep 7.


Evaluation of cell proliferation and cell death based assays in chemosensitivity testing.

Gerçel-Taylor C, Ackermann MA, Taylor DD.

Anticancer Res. 2001 Jul-Aug;21(4A):2761-8.


Supplemental Content

Loading ...
Support Center