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Repeat adverse drug events associated with outpatient medications: a descriptive analysis of 3 observational studies in British Columbia, Canada.

Hohl CM, Woo SA, Cragg A, Wickham ME, Ackerley C, Scheuermeyer F, Villanyi D.

CMAJ Open. 2019 Jul 18;7(3):E446-E453. doi: 10.9778/cmajo.20180190. Print 2019 Jul-Sep.


Autophagy is required for lung development and morphogenesis.

Yeganeh B, Lee J, Ermini L, Lok I, Ackerley C, Post M.

J Clin Invest. 2019 Jun 4;129(7):2904-2919. doi: 10.1172/JCI127307. eCollection 2019 Jun 4.


Distribution of Functional CD4 and CD8 T cell Subsets in Blood and Rectal Mucosal Tissues.

Amancha PK, Ackerley CG, Duphare C, Lee M, Hu YJ, Amara RR, Kelley CF.

Sci Rep. 2019 May 6;9(1):6951. doi: 10.1038/s41598-019-43311-6.


Human Immunodeficiency Virus in Transgender Persons.

Ackerley CG, Poteat T, Kelley CF.

Endocrinol Metab Clin North Am. 2019 Jun;48(2):453-464. doi: 10.1016/j.ecl.2019.02.007. Epub 2019 Mar 23. Review.


Acid Sphingomyelinase Inhibition Attenuates Cell Death in Mechanically Ventilated Newborn Rat Lung.

Yeganeh B, Lee J, Bilodeau C, Lok I, Ermini L, Ackerley C, Caniggia I, Tibboel J, Kroon A, Post M.

Am J Respir Crit Care Med. 2019 Mar 15;199(6):760-772. doi: 10.1164/rccm.201803-0583OC.


Enhancing glioblastoma treatment using cisplatin-gold-nanoparticle conjugates and targeted delivery with magnetic resonance-guided focused ultrasound.

Coluccia D, Figueiredo CA, Wu MY, Riemenschneider AN, Diaz R, Luck A, Smith C, Das S, Ackerley C, O'Reilly M, Hynynen K, Rutka JT.

Nanomedicine. 2018 Jun;14(4):1137-1148. doi: 10.1016/j.nano.2018.01.021. Epub 2018 Feb 20.


Patient Perceptions About Data Sharing & Privacy: Insights from ActionADE.

Small SS, Peddie D, Ackerley C, Hohl CM, Balka E.

Stud Health Technol Inform. 2017;241:109-114.


Lafora disease in miniature Wirehaired Dachshunds.

Swain L, Key G, Tauro A, Ahonen S, Wang P, Ackerley C, Minassian BA, Rusbridge C.

PLoS One. 2017 Aug 2;12(8):e0182024. doi: 10.1371/journal.pone.0182024. eCollection 2017.


Lafora disease.

Turnbull J, Tiberia E, Striano P, Genton P, Carpenter S, Ackerley CA, Minassian BA.

Epileptic Disord. 2016 Sep 1;18(S2):38-62. Review.


Fatal hepatic failure and pontine and extrapontine myelinolysis in XMEA.

Ackerley CA, Cooper MA, Munoz DG, Minassian BA.

Neurology. 2016 Sep 27;87(13):1417-9. doi: 10.1212/WNL.0000000000003155. Epub 2016 Aug 26. No abstract available.


Designing an Adverse Drug Event Reporting System to Prevent Unintentional Reexposures to Harmful Drugs: Study Protocol for a Multiple Methods Design.

Peddie D, Small SS, Badke K, Wickham ME, Bailey C, Chruscicki A, Ackerley C, Balka E, Hohl CM.

JMIR Res Protoc. 2016 Aug 18;5(3):e169. doi: 10.2196/resprot.5967.


Generation of ESC-derived Mouse Airway Epithelial Cells Using Decellularized Lung Scaffolds.

Shojaie S, Lee J, Wang J, Ackerley C, Post M.

J Vis Exp. 2016 May 5;(111). doi: 10.3791/54019.


Alveolar-like Stem Cell-derived Myb(-) Macrophages Promote Recovery and Survival in Airway Disease.

Litvack ML, Wigle TJ, Lee J, Wang J, Ackerley C, Grunebaum E, Post M.

Am J Respir Crit Care Med. 2016 Jun 1;193(11):1219-29. doi: 10.1164/rccm.201509-1838OC.


Evolutionarily conserved intercalated disc protein Tmem65 regulates cardiac conduction and connexin 43 function.

Sharma P, Abbasi C, Lazic S, Teng ACT, Wang D, Dubois N, Ignatchenko V, Wong V, Liu J, Araki T, Tiburcy M, Ackerley C, Zimmermann WH, Hamilton R, Sun Y, Liu PP, Keller G, Stagljar I, Scott IC, Kislinger T, Gramolini AO.

Nat Commun. 2015 Sep 25;6:8391. doi: 10.1038/ncomms9391.


A low-protein diet combined with low-dose endotoxin leads to changes in glucose homeostasis in weanling rats.

Bandsma RH, Ackerley C, Koulajian K, Zhang L, van Zutphen T, van Dijk TH, Xiao C, Giacca A, Lewis GF.

Am J Physiol Endocrinol Metab. 2015 Sep 1;309(5):E466-73. doi: 10.1152/ajpendo.00090.2015. Epub 2015 Jul 7.


Acellular lung scaffolds direct differentiation of endoderm to functional airway epithelial cells: requirement of matrix-bound HS proteoglycans.

Shojaie S, Ermini L, Ackerley C, Wang J, Chin S, Yeganeh B, Bilodeau M, Sambi M, Rogers I, Rossant J, Bear CE, Post M.

Stem Cell Reports. 2015 Mar 10;4(3):419-30. doi: 10.1016/j.stemcr.2015.01.004. Epub 2015 Feb 5.


Aggregates of mutant CFTR fragments in airway epithelial cells of CF lungs: new pathologic observations.

Du K, Karp PH, Ackerley C, Zabner J, Keshavjee S, Cutz E, Yeger H.

J Cyst Fibros. 2015 Mar;14(2):182-93. doi: 10.1016/j.jcf.2014.09.012. Epub 2014 Oct 28.


Identification of a proximal progenitor population from murine fetal lungs with clonogenic and multilineage differentiation potential.

Bilodeau M, Shojaie S, Ackerley C, Post M, Rossant J.

Stem Cell Reports. 2014 Oct 14;3(4):634-49. doi: 10.1016/j.stemcr.2014.07.010. Epub 2014 Sep 4.


TMEM43 mutation p.S358L alters intercalated disc protein expression and reduces conduction velocity in arrhythmogenic right ventricular cardiomyopathy.

Siragam V, Cui X, Masse S, Ackerley C, Aafaqi S, Strandberg L, Tropak M, Fridman MD, Nanthakumar K, Liu J, Sun Y, Su B, Wang C, Liu X, Yan Y, Mendlowitz A, Hamilton RM.

PLoS One. 2014 Oct 24;9(10):e109128. doi: 10.1371/journal.pone.0109128. eCollection 2014.


Single point mutation in Rabenosyn-5 in a female with intractable seizures and evidence of defective endocytotic trafficking.

Stockler S, Corvera S, Lambright D, Fogarty K, Nosova E, Leonard D, Steinfeld R, Ackerley C, Shyr C, Au N, Selby K, van Allen M, Vallance H, Wevers R, Watkins D, Rosenblatt D, Ross CJ, Conibear E, Wasserman W, van Karnebeek C.

Orphanet J Rare Dis. 2014 Sep 20;9:141. doi: 10.1186/s13023-014-0141-5.


Hypoxia-inducible factor-1 stimulates postnatal lung development but does not prevent O2-induced alveolar injury.

Tibboel J, Groenman FA, Selvaratnam J, Wang J, Tseu I, Huang Z, Caniggia I, Luo D, van Tuyl M, Ackerley C, de Jongste JC, Tibboel D, Post M.

Am J Respir Cell Mol Biol. 2015 Apr;52(4):448-58. doi: 10.1165/rcmb.2014-0037OC.


Three-dimensional culture and FGF signaling drive differentiation of murine pluripotent cells to distal lung epithelial cells.

Fox E, Shojaie S, Wang J, Tseu I, Ackerley C, Bilodeau M, Post M.

Stem Cells Dev. 2015 Jan 1;24(1):21-35. doi: 10.1089/scd.2014.0227.


Pulmonary alveolar proteinosis in adenosine deaminase-deficient mice.

Dhanju R, Min W, Ackerley C, Cimpean L, Palaniyar N, Roifman CM, Grunebaum E.

J Allergy Clin Immunol. 2014 May;133(5):1467-71, 1471.e1-4. doi: 10.1016/j.jaci.2013.11.029. Epub 2014 Jan 15. No abstract available.


PTG protein depletion rescues malin-deficient Lafora disease in mouse.

Turnbull J, Epp JR, Goldsmith D, Zhao X, Pencea N, Wang P, Frankland PW, Ackerley CA, Minassian BA.

Ann Neurol. 2014 Mar;75(3):442-6. doi: 10.1002/ana.24104. Epub 2014 Mar 7.


The intestinal epithelial insulin-like growth factor-1 receptor links glucagon-like peptide-2 action to gut barrier function.

Dong CX, Zhao W, Solomon C, Rowland KJ, Ackerley C, Robine S, Holzenberger M, Gonska T, Brubaker PL.

Endocrinology. 2014 Feb;155(2):370-9. doi: 10.1210/en.2013-1871. Epub 2013 Nov 21.


Deficiency of a glycogen synthase-associated protein, Epm2aip1, causes decreased glycogen synthesis and hepatic insulin resistance.

Turnbull J, Tiberia E, Pereira S, Zhao X, Pencea N, Wheeler AL, Yu WQ, Ivovic A, Naranian T, Israelian N, Draginov A, Piliguian M, Frankland PW, Wang P, Ackerley CA, Giacca A, Minassian BA.

J Biol Chem. 2013 Nov 29;288(48):34627-37. doi: 10.1074/jbc.M113.483198. Epub 2013 Oct 18.


Congenital heart block maternal sera autoantibodies target an extracellular epitope on the α1G T-type calcium channel in human fetal hearts.

Strandberg LS, Cui X, Rath A, Liu J, Silverman ED, Liu X, Siragam V, Ackerley C, Su BB, Yan JY, Capecchi M, Biavati L, Accorroni A, Yuen W, Quattrone F, Lung K, Jaeggi ET, Backx PH, Deber CM, Hamilton RM.

PLoS One. 2013 Sep 9;8(9):e72668. doi: 10.1371/journal.pone.0072668. eCollection 2013.


Inhibiting glycogen synthesis prevents Lafora disease in a mouse model.

Pederson BA, Turnbull J, Epp JR, Weaver SA, Zhao X, Pencea N, Roach PJ, Frankland PW, Ackerley CA, Minassian BA.

Ann Neurol. 2013 Aug;74(2):297-300. doi: 10.1002/ana.23899.


Fetal, but not postnatal, deletion of semaphorin-neuropilin-1 signaling affects murine alveolar development.

Joza S, Wang J, Tseu I, Ackerley C, Post M.

Am J Respir Cell Mol Biol. 2013 Oct;49(4):627-36. doi: 10.1165/rcmb.2012-0407OC.


Genome-wide association analysis identifies a mutation in the thiamine transporter 2 (SLC19A3) gene associated with Alaskan Husky encephalopathy.

Vernau KM, Runstadler JA, Brown EA, Cameron JM, Huson HJ, Higgins RJ, Ackerley C, Sturges BK, Dickinson PJ, Puschner B, Giulivi C, Shelton GD, Robinson BH, DiMauro S, Bollen AW, Bannasch DL.

PLoS One. 2013;8(3):e57195. doi: 10.1371/journal.pone.0057195. Epub 2013 Mar 4.


VMA21 deficiency prevents vacuolar ATPase assembly and causes autophagic vacuolar myopathy.

Ramachandran N, Munteanu I, Wang P, Ruggieri A, Rilstone JJ, Israelian N, Naranian T, Paroutis P, Guo R, Ren ZP, Nishino I, Chabrol B, Pellissier JF, Minetti C, Udd B, Fardeau M, Tailor CS, Mahuran DJ, Kissel JT, Kalimo H, Levy N, Manolson MF, Ackerley CA, Minassian BA.

Acta Neuropathol. 2013 Mar;125(3):439-57. doi: 10.1007/s00401-012-1073-6. Epub 2013 Jan 12.


Mitochondrial citrate synthase crystals: novel finding in Sengers syndrome caused by acylglycerol kinase (AGK) mutations.

Siriwardena K, Mackay N, Levandovskiy V, Blaser S, Raiman J, Kantor PF, Ackerley C, Robinson BH, Schulze A, Cameron JM.

Mol Genet Metab. 2013 Jan;108(1):40-50. doi: 10.1016/j.ymgme.2012.11.282. Epub 2012 Dec 3.


Inhibition of peptidyl-arginine deiminases reverses protein-hypercitrullination and disease in mouse models of multiple sclerosis.

Moscarello MA, Lei H, Mastronardi FG, Winer S, Tsui H, Li Z, Ackerley C, Zhang L, Raijmakers R, Wood DD.

Dis Model Mech. 2013 Mar;6(2):467-78. doi: 10.1242/dmm.010520. Epub 2012 Nov 1.


Loss of semaphorin-neuropilin-1 signaling causes dysmorphic vascularization reminiscent of alveolar capillary dysplasia.

Joza S, Wang J, Fox E, Hillman V, Ackerley C, Post M.

Am J Pathol. 2012 Dec;181(6):2003-17. doi: 10.1016/j.ajpath.2012.08.037. Epub 2012 Oct 12.


Early-onset Lafora body disease.

Turnbull J, Girard JM, Lohi H, Chan EM, Wang P, Tiberia E, Omer S, Ahmed M, Bennett C, Chakrabarty A, Tyagi A, Liu Y, Pencea N, Zhao X, Scherer SW, Ackerley CA, Minassian BA.

Brain. 2012 Sep;135(Pt 9):2684-98. doi: 10.1093/brain/aws205.


Increased laforin and laforin binding to glycogen underlie Lafora body formation in malin-deficient Lafora disease.

Tiberia E, Turnbull J, Wang T, Ruggieri A, Zhao XC, Pencea N, Israelian J, Wang Y, Ackerley CA, Wang P, Liu Y, Minassian BA.

J Biol Chem. 2012 Jul 20;287(30):25650-9. doi: 10.1074/jbc.M111.331611. Epub 2012 Jun 5.


Phosphorylation prevents polyglucosan transport in Lafora disease.

Girard JM, Stone SS, Lohi H, Blaszykowski C, Teixeira C, Turnbull J, Wang A, Draginov A, Wang P, Zhao XC, Ackerley CA, Frankland PW, Minassian BA.

Neurology. 2012 Jul 3;79(1):100-2. doi: 10.1212/WNL.0b013e31825dcdac. Epub 2012 May 23. No abstract available.


Cerebellar abnormalities in purine nucleoside phosphorylase deficient mice.

Mansouri A, Min W, Cole CJ, Josselyn SA, Henderson JT, van Eede M, Henkelman RM, Ackerley C, Grunebaum E, Roifman CM.

Neurobiol Dis. 2012 Aug;47(2):201-9. doi: 10.1016/j.nbd.2012.04.001. Epub 2012 Apr 11.


Primary nasal histiocytic sarcoma of macrophage-myeloid cell type in a cat.

Wong VM, Snyman HN, Ackerley C, Bienzle D.

J Comp Pathol. 2012 Aug-Oct;147(2-3):209-13. doi: 10.1016/j.jcpa.2012.01.015. Epub 2012 Apr 20.


Effects of purine nucleoside phosphorylase deficiency on thymocyte development.

Papinazath T, Min W, Sujiththa S, Cohen A, Ackerley C, Roifman CM, Grunebaum E.

J Allergy Clin Immunol. 2011 Oct;128(4):854-863.e1. doi: 10.1016/j.jaci.2011.07.039. Epub 2011 Aug 25.


PTG depletion removes Lafora bodies and rescues the fatal epilepsy of Lafora disease.

Turnbull J, DePaoli-Roach AA, Zhao X, Cortez MA, Pencea N, Tiberia E, Piliguian M, Roach PJ, Wang P, Ackerley CA, Minassian BA.

PLoS Genet. 2011 Apr;7(4):e1002037. doi: 10.1371/journal.pgen.1002037. Epub 2011 Apr 28.


Lafora bodies in skeletal muscle are fiber type specific.

Turnbull J, Girard JM, Pencea N, Zhao X, Graham TE, Wang P, Ackerley CA, Minassian BA.

Neurology. 2011 May 10;76(19):1674-6. doi: 10.1212/WNL.0b013e318219faf6. Epub 2011 Mar 30. No abstract available.


Upregulation of mammary gland OCTNs maintains carnitine homeostasis in suckling infants.

Lamhonwah AM, Mai L, Chung C, Lamhonwah D, Ackerley C, Tein I.

Biochem Biophys Res Commun. 2011 Jan 28;404(4):1010-5. doi: 10.1016/j.bbrc.2010.12.100. Epub 2010 Dec 25.


Glycogen hyperphosphorylation underlies lafora body formation.

Turnbull J, Wang P, Girard JM, Ruggieri A, Wang TJ, Draginov AG, Kameka AP, Pencea N, Zhao X, Ackerley CA, Minassian BA.

Ann Neurol. 2010 Dec;68(6):925-33. doi: 10.1002/ana.22156.


Complex V TMEM70 deficiency results in mitochondrial nucleoid disorganization.

Cameron JM, Levandovskiy V, Mackay N, Ackerley C, Chitayat D, Raiman J, Halliday WH, Schulze A, Robinson BH.

Mitochondrion. 2011 Jan;11(1):191-9. doi: 10.1016/j.mito.2010.09.008. Epub 2010 Oct 30.


Clara cell secretory protein increases phagocytic and decreases oxidative activity of neutrophils.

Katavolos P, Ackerley CA, Clark ME, Bienzle D.

Vet Immunol Immunopathol. 2011 Jan;139(1):1-9. doi: 10.1016/j.vetimm.2010.07.021. Epub 2010 Aug 6.


A major fraction of glycosphingolipids in model and cellular cholesterol-containing membranes is undetectable by their binding proteins.

Mahfoud R, Manis A, Binnington B, Ackerley C, Lingwood CA.

J Biol Chem. 2010 Nov 12;285(46):36049-59. doi: 10.1074/jbc.M110.110189. Epub 2010 Aug 17.


Septins regulate developmental switching from microdomain to nanodomain coupling of Ca(2+) influx to neurotransmitter release at a central synapse.

Yang YM, Fedchyshyn MJ, Grande G, Aitoubah J, Tsang CW, Xie H, Ackerley CA, Trimble WS, Wang LY.

Neuron. 2010 Jul 15;67(1):100-15. doi: 10.1016/j.neuron.2010.06.003.


Cystic fibrosis transmembrane conductance regulator in human muscle: Dysfunction causes abnormal metabolic recovery in exercise.

Lamhonwah AM, Bear CE, Huan LJ, Kim Chiaw P, Ackerley CA, Tein I.

Ann Neurol. 2010 Jun;67(6):802-8. doi: 10.1002/ana.21982.


Experimental induction of recurrent airway obstruction with inhaled fungal spores, lipopolysaccharide, and silica microspheres in horses.

Beeler-Marfisi J, Clark ME, Wen X, Sears W, Huber L, Ackerley C, Viel L, Bienzle D.

Am J Vet Res. 2010 Jun;71(6):682-9. doi: 10.2460/ajvr.71.6.682.


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