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Items: 28


Autocrine IFN-I inhibits isocitrate dehydrogenase in the TCA cycle of LPS-stimulated macrophages.

De Souza DP, Achuthan A, Lee MK, Binger KJ, Lee MC, Davidson S, Tull DL, McConville MJ, Cook AD, Murphy AJ, Hamilton JA, Fleetwood AJ.

J Clin Invest. 2019 Oct 1;129(10):4239-4244. doi: 10.1172/JCI127597.


Macrophage spatial heterogeneity in gastric cancer defined by multiplex immunohistochemistry.

Huang YK, Wang M, Sun Y, Di Costanzo N, Mitchell C, Achuthan A, Hamilton JA, Busuttil RA, Boussioutas A.

Nat Commun. 2019 Sep 2;10(1):3928. doi: 10.1038/s41467-019-11788-4.


GM-CSF- and IRF4-Dependent Signaling Can Regulate Myeloid Cell Numbers and the Macrophage Phenotype during Inflammation.

Lee MC, Lacey DC, Fleetwood AJ, Achuthan A, Hamilton JA, Cook AD.

J Immunol. 2019 May 15;202(10):3033-3040. doi: 10.4049/jimmunol.1801549. Epub 2019 Apr 15.


CSF-1 in Inflammatory and Arthritic Pain Development.

Saleh R, Lee MC, Khiew SH, Louis C, Fleetwood AJ, Achuthan A, Förster I, Cook AD, Hamilton JA.

J Immunol. 2018 Oct 1;201(7):2042-2053. doi: 10.4049/jimmunol.1800665. Epub 2018 Aug 17.


Epigenetic and transcriptional regulation of IL4-induced CCL17 production in human monocytes and murine macrophages.

Hsu AT, Lupancu TJ, Lee MC, Fleetwood AJ, Cook AD, Hamilton JA, Achuthan A.

J Biol Chem. 2018 Jul 20;293(29):11415-11423. doi: 10.1074/jbc.RA118.002416. Epub 2018 Jun 5.


Cytokine-Induced Acute Inflammatory Monoarticular Arthritis.

Achuthan A, Lee MC, Saleh R, Fleetwood AJ, Hamilton JA, Cook AD.

Methods Mol Biol. 2018;1784:215-223. doi: 10.1007/978-1-4939-7837-3_20.


CCL17 blockade as a therapy for osteoarthritis pain and disease.

Lee MC, Saleh R, Achuthan A, Fleetwood AJ, Förster I, Hamilton JA, Cook AD.

Arthritis Res Ther. 2018 Apr 5;20(1):62. doi: 10.1186/s13075-018-1560-9.


TNF and granulocyte macrophage-colony stimulating factor interdependence mediates inflammation via CCL17.

Cook AD, Lee MC, Saleh R, Khiew HW, Christensen AD, Achuthan A, Fleetwood AJ, Lacey DC, Smith JE, Förster I, Hamilton JA.

JCI Insight. 2018 Mar 22;3(6). pii: 99249. doi: 10.1172/jci.insight.99249.


Glucocorticoids promote apoptosis of proinflammatory monocytes by inhibiting ERK activity.

Achuthan A, Aslam ASM, Nguyen Q, Lam PY, Fleetwood AJ, Frye AT, Louis C, Lee MC, Smith JE, Cook AD, Olshansky M, Turner SJ, Hamilton JA.

Cell Death Dis. 2018 Feb 15;9(3):267. doi: 10.1038/s41419-018-0332-4.


Metabolic Remodeling, Inflammasome Activation, and Pyroptosis in Macrophages Stimulated by Porphyromonas gingivalis and Its Outer Membrane Vesicles.

Fleetwood AJ, Lee MKS, Singleton W, Achuthan A, Lee MC, O'Brien-Simpson NM, Cook AD, Murphy AJ, Dashper SG, Reynolds EC, Hamilton JA.

Front Cell Infect Microbiol. 2017 Aug 4;7:351. doi: 10.3389/fcimb.2017.00351. eCollection 2017.


G-CSF Receptor Blockade Ameliorates Arthritic Pain and Disease.

Lee MC, McCubbin JA, Christensen AD, Poole DP, Rajasekhar P, Lieu T, Bunnett NW, Garcia-Caraballo S, Erickson A, Brierley SM, Saleh R, Achuthan A, Fleetwood AJ, Anderson RL, Hamilton JA, Cook AD.

J Immunol. 2017 May 1;198(9):3565-3575. doi: 10.4049/jimmunol.1602127. Epub 2017 Mar 20.


A Bio Medical Waste Identification and Classification Algorithm Using Mltrp and Rvm.

Achuthan A, Ayyallu Madangopal V.

Iran J Public Health. 2016 Oct;45(10):1276-1287.


Granulocyte macrophage colony-stimulating factor induces CCL17 production via IRF4 to mediate inflammation.

Achuthan A, Cook AD, Lee MC, Saleh R, Khiew HW, Chang MW, Louis C, Fleetwood AJ, Lacey DC, Christensen AD, Frye AT, Lam PY, Kusano H, Nomura K, Steiner N, Förster I, Nutt SL, Olshansky M, Turner SJ, Hamilton JA.

J Clin Invest. 2016 Sep 1;126(9):3453-66. doi: 10.1172/JCI87828. Epub 2016 Aug 15.


A Multiscale Computational Model Combining a Single Crystal Plasticity Constitutive Model with the Generalized Method of Cells (GMC) for Metallic Polycrystals.

Ghorbani Moghaddam M, Achuthan A, Bednarcyk BA, Arnold SM, Pineda EJ.

Materials (Basel). 2016 May 4;9(5). pii: E335. doi: 10.3390/ma9050335.


IRF6 Regulates the Expression of IL-36γ by Human Oral Epithelial Cells in Response to Porphyromonas gingivalis.

Huynh J, Scholz GM, Aw J, Kwa MQ, Achuthan A, Hamilton JA, Reynolds EC.

J Immunol. 2016 Mar 1;196(5):2230-8. doi: 10.4049/jimmunol.1501263. Epub 2016 Jan 27.


Porphyromonas gingivalis-derived RgpA-Kgp Complex Activates the Macrophage Urokinase Plasminogen Activator System: IMPLICATIONS FOR PERIODONTITIS.

Fleetwood AJ, O'Brien-Simpson NM, Veith PD, Lam RS, Achuthan A, Cook AD, Singleton W, Lund IK, Reynolds EC, Hamilton JA.

J Biol Chem. 2015 Jun 26;290(26):16031-42. doi: 10.1074/jbc.M115.645572. Epub 2015 May 15.


Modal response of a computational vocal fold model with a substrate layer of adipose tissue.

Jones CL, Achuthan A, Erath BD.

J Acoust Soc Am. 2015 Feb;137(2):EL158-64. doi: 10.1121/1.4905892.


Urokinase plasminogen activator is a central regulator of macrophage three-dimensional invasion, matrix degradation, and adhesion.

Fleetwood AJ, Achuthan A, Schultz H, Nansen A, Almholt K, Usher P, Hamilton JA.

J Immunol. 2014 Apr 15;192(8):3540-7. doi: 10.4049/jimmunol.1302864. Epub 2014 Mar 10.


Colony stimulating factors and myeloid cell biology in health and disease.

Hamilton JA, Achuthan A.

Trends Immunol. 2013 Feb;34(2):81-9. doi: 10.1016/ Epub 2012 Sep 21. Review.


Defining GM-CSF- and macrophage-CSF-dependent macrophage responses by in vitro models.

Lacey DC, Achuthan A, Fleetwood AJ, Dinh H, Roiniotis J, Scholz GM, Chang MW, Beckman SK, Cook AD, Hamilton JA.

J Immunol. 2012 Jun 1;188(11):5752-65. doi: 10.4049/jimmunol.1103426. Epub 2012 Apr 30.


Antioxidative potential of lactobacilli isolated from the gut of Indian people.

Achuthan AA, Duary RK, Madathil A, Panwar H, Kumar H, Batish VK, Grover S.

Mol Biol Rep. 2012 Aug;39(8):7887-97. doi: 10.1007/s11033-012-1633-9. Epub 2012 May 1.


Wavelet energy-guided level set-based active contour: a segmentation method to segment highly similar regions.

Achuthan A, Rajeswari M, Ramachandram D, Aziz ME, Shuaib IL.

Comput Biol Med. 2010 Jul;40(7):608-20. doi: 10.1016/j.compbiomed.2010.04.005. Epub 2010 Jun 11.


Regulation of the endosomal SNARE protein syntaxin 7 by colony-stimulating factor 1 in macrophages.

Achuthan A, Masendycz P, Lopez JA, Nguyen T, James DE, Sweet MJ, Hamilton JA, Scholz GM.

Mol Cell Biol. 2008 Oct;28(20):6149-59. doi: 10.1128/MCB.00220-08. Epub 2008 Aug 18.


CpG DNA enhances macrophage cell spreading by promoting the Src-family kinase-mediated phosphorylation of paxillin.

Achuthan A, Elsegood C, Masendycz P, Hamilton JA, Scholz GM.

Cell Signal. 2006 Dec;18(12):2252-61. Epub 2006 May 23.


A potential role for the Src-like adapter protein SLAP-2 in signaling by the colony stimulating factor-1 receptor.

Manes GA, Masendycz P, Nguyen T, Achuthan A, Dinh H, Hamilton JA, Scholz GM.

FEBS J. 2006 Apr;273(8):1791-804.


Tuning of intercalation and electron-transfer processes between DNA and acridinium derivatives through steric effects.

Joseph J, Kuruvilla E, Achuthan AT, Ramaiah D, Schuster GB.

Bioconjug Chem. 2004 Nov-Dec;15(6):1230-5.


Hypopituitarism following snake bite.

Uberoi HS, Achuthan AC, Kasthuri AS, Kolhe VS, Rao KR, Dugal JS.

J Assoc Physicians India. 1991 Jul;39(7):579-80.


Fulminant Case of Ulcerative Endocarditis.

Achuthan A, Kelu M.

Ind Med Gaz. 1938 Dec;73(12):740-741. No abstract available.

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