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Items: 42

1.

Co-infections of human herpesviruses (CMV, HHV-6, HHV-7 and EBV) in non-transplant acute leukemia patients undergoing chemotherapy.

Handous I, Achour B, Marzouk M, Rouis S, Hazgui O, Brini I, Khelif A, Hannachi N, Boukadida J.

Virol J. 2020 Mar 17;17(1):37. doi: 10.1186/s12985-020-01302-4.

2.

Mass Spectrometry of Human Transporters.

Achour B, Al-Majdoub Z, Rostami-Hodjegan A, Barber J.

Annu Rev Anal Chem (Palo Alto Calif). 2020 Feb 21. doi: 10.1146/annurev-anchem-091719-024553. [Epub ahead of print]

PMID:
32084322
3.

Quantitative Proteomics of Clinically Relevant Drug-Metabolizing Enzymes and Drug Transporters and Their Intercorrelations in the Human Small Intestine.

Couto N, Al-Majdoub ZM, Gibson S, Davies PJ, Achour B, Harwood MD, Carlson G, Barber J, Rostami-Hodjegan A, Warhurst G.

Drug Metab Dispos. 2020 Apr;48(4):245-254. doi: 10.1124/dmd.119.089656. Epub 2020 Jan 20.

PMID:
31959703
4.

Characterization of CYP2B6 K262R allelic variants by quantitative allele-specific proteomics using a QconCAT standard.

Barber J, Russell MR, Rostami-Hodjegan A, Achour B.

J Pharm Biomed Anal. 2020 Jan 30;178:112901. doi: 10.1016/j.jpba.2019.112901. Epub 2019 Oct 3.

PMID:
31610395
5.

Quantitative mass spectrometry-based proteomics in the era of model-informed drug development: Applications in translational pharmacology and recommendations for best practice.

El-Khateeb E, Vasilogianni AM, Alrubia S, Al-Majdoub ZM, Couto N, Howard M, Barber J, Rostami-Hodjegan A, Achour B.

Pharmacol Ther. 2019 Nov;203:107397. doi: 10.1016/j.pharmthera.2019.107397. Epub 2019 Jul 31. Review.

PMID:
31376433
6.

Toward a Consensus on Applying Quantitative Liquid Chromatography-Tandem Mass Spectrometry Proteomics in Translational Pharmacology Research: A White Paper.

Prasad B, Achour B, Artursson P, Hop CECA, Lai Y, Smith PC, Barber J, Wisniewski JR, Spellman D, Uchida Y, Zientek MA, Unadkat JD, Rostami-Hodjegan A.

Clin Pharmacol Ther. 2019 Sep;106(3):525-543. doi: 10.1002/cpt.1537. Epub 2019 Jul 26.

PMID:
31175671
7.

Proteomic Quantification of Human Blood-Brain Barrier SLC and ABC Transporters in Healthy Individuals and Dementia Patients.

Al-Majdoub ZM, Al Feteisi H, Achour B, Warwood S, Neuhoff S, Rostami-Hodjegan A, Barber J.

Mol Pharm. 2019 Mar 4;16(3):1220-1233. doi: 10.1021/acs.molpharmaceut.8b01189. Epub 2019 Feb 8.

PMID:
30735053
8.

Quantification of Proteins Involved in Drug Metabolism and Disposition in the Human Liver Using Label-Free Global Proteomics.

Couto N, Al-Majdoub ZM, Achour B, Wright PC, Rostami-Hodjegan A, Barber J.

Mol Pharm. 2019 Feb 4;16(2):632-647. doi: 10.1021/acs.molpharmaceut.8b00941. Epub 2019 Jan 18.

PMID:
30608694
9.

Response to "Determining Allele-Specific Protein Expression (ASPE) Using a Novel Quantitative Concatamer Based Proteomics Method".

Achour B, Rostami-Hodjegan A, Barber J.

J Proteome Res. 2019 Jan 4;18(1):574. doi: 10.1021/acs.jproteome.8b00871. Epub 2018 Nov 20.

PMID:
30444614
10.

GASP and FASP are Complementary for LC-MS/MS Proteomic Analysis of Drug-Metabolizing Enzymes and Transporters in Pig Liver.

Howard M, Achour B, Al-Majdoub Z, Rostami-Hodjegan A, Barber J.

Proteomics. 2018 Dec;18(24):e1800200. doi: 10.1002/pmic.201800200. Epub 2018 Nov 30.

PMID:
30371990
11.

Antiglaucomatous treatments and ocular surface.

Lajmi H, Ben Jalel W, Hmaied W, Zahaf A, Ben Achour B, El Fekih L.

Tunis Med. 2017 Jul;95(7):477-481.

12.

Identification and quantification of blood-brain barrier transporters in isolated rat brain microvessels.

Al Feteisi H, Al-Majdoub ZM, Achour B, Couto N, Rostami-Hodjegan A, Barber J.

J Neurochem. 2018 Sep;146(6):670-685. doi: 10.1111/jnc.14446. Epub 2018 Aug 1.

13.

Data Generated by Quantitative Liquid Chromatography-Mass Spectrometry Proteomics Are Only the Start and Not the Endpoint: Optimization of Quantitative Concatemer-Based Measurement of Hepatic Uridine-5'-Diphosphate-Glucuronosyltransferase Enzymes with Reference to Catalytic Activity.

Achour B, Dantonio A, Niosi M, Novak JJ, Al-Majdoub ZM, Goosen TC, Rostami-Hodjegan A, Barber J.

Drug Metab Dispos. 2018 Jun;46(6):805-812. doi: 10.1124/dmd.117.079475. Epub 2018 Mar 26.

PMID:
29581103
14.

Implications of intercorrelation between hepatic CYP3A4-CYP2C8 enzymes for the evaluation of drug-drug interactions: a case study with repaglinide.

Doki K, Darwich AS, Achour B, Tornio A, Backman JT, Rostami-Hodjegan A.

Br J Clin Pharmacol. 2018 May;84(5):972-986. doi: 10.1111/bcp.13533. Epub 2018 Mar 6.

15.

Primary spinal marginal zone lymphoma: an unusual cause of spinal cord compression.

Alaya Z, Achour B.

Pan Afr Med J. 2017 Jul 4;27:171. doi: 10.11604/pamj.2017.27.171.11947. eCollection 2017. No abstract available.

16.

[Granulocytic sarcoma of the dorsal spine: an unusual cause of spinal cord compression].

Alaya Z, Achour B.

Pan Afr Med J. 2017 May 24;27:56. doi: 10.11604/pamj.2017.27.56.11935. eCollection 2017. French. No abstract available.

17.

Quantitative Characterization of Major Hepatic UDP-Glucuronosyltransferase Enzymes in Human Liver Microsomes: Comparison of Two Proteomic Methods and Correlation with Catalytic Activity.

Achour B, Dantonio A, Niosi M, Novak JJ, Fallon JK, Barber J, Smith PC, Rostami-Hodjegan A, Goosen TC.

Drug Metab Dispos. 2017 Oct;45(10):1102-1112. doi: 10.1124/dmd.117.076703. Epub 2017 Aug 2.

PMID:
28768682
18.

Variability in Mass Spectrometry-based Quantification of Clinically Relevant Drug Transporters and Drug Metabolizing Enzymes.

Wegler C, Gaugaz FZ, Andersson TB, Wiśniewski JR, Busch D, Gröer C, Oswald S, Norén A, Weiss F, Hammer HS, Joos TO, Poetz O, Achour B, Rostami-Hodjegan A, van de Steeg E, Wortelboer HM, Artursson P.

Mol Pharm. 2017 Sep 5;14(9):3142-3151. doi: 10.1021/acs.molpharmaceut.7b00364. Epub 2017 Aug 16.

19.

Global Proteomic Analysis of Human Liver Microsomes: Rapid Characterization and Quantification of Hepatic Drug-Metabolizing Enzymes.

Achour B, Al Feteisi H, Lanucara F, Rostami-Hodjegan A, Barber J.

Drug Metab Dispos. 2017 Jun;45(6):666-675. doi: 10.1124/dmd.116.074732. Epub 2017 Apr 3.

PMID:
28373266
20.

Minimal residual disease detection in Tunisian B-acute lymphoblastic leukemia based on immunoglobulin gene rearrangements.

Besbes S, Hamadou WS, Boulland ML, Youssef YB, Achour B, Regaieg H, Khelif A, Fest T, Soua Z.

Braz J Med Biol Res. 2017 Jan 16;50(1):e5426. doi: 10.1590/1414-431X20165426.

21.

ARLTS1, potential candidate gene in familial aggregation of hematological malignancies.

Hamadou WS, Besbes S, Mani R, Bourdon V, Ben Youssef Y, Achour B, Regaieg H, Eisinger F, Mari V, Gesta P, Dreyfus H, Bonadona V, Dugast C, Zattara H, Faivre L, Noguchi T, Khélif A, Sobol H, Soua Z.

Bull Cancer. 2017 Feb;104(2):123-127. doi: 10.1016/j.bulcan.2016.10.016. Epub 2016 Nov 17.

PMID:
27866680
22.

[Juvenile myelomonocytic leukemia: A three-case series].

Ghariani I, Jmili-Braham N, Regaieg H, Achour B, Ben Youssef Y, Sendi H, Bakir L, Kortas M.

Arch Pediatr. 2016 Dec;23(12):1264-1269. doi: 10.1016/j.arcped.2016.09.007. Epub 2016 Oct 24. French.

PMID:
27789175
23.

Combined IKZF1 and IG markers as new tools for diagnosis and minimal residual disease assessment in Tunisian B-ALL.

Besbes S, Hamadou WS, Boulland ML, Lefranc MP, Ben Youssef Y, Achour B, Khelif A, Fest T, Soua Z.

Bull Cancer. 2016 Oct;103(10):822-828. doi: 10.1016/j.bulcan.2016.07.008. Epub 2016 Sep 7.

PMID:
27614734
24.

In Vitro-In Vivo Extrapolation Scaling Factors for Intestinal P-glycoprotein and Breast Cancer Resistance Protein: Part II. The Impact of Cross-Laboratory Variations of Intestinal Transporter Relative Expression Factors on Predicted Drug Disposition.

Harwood MD, Achour B, Neuhoff S, Russell MR, Carlson G, Warhurst G, Rostami-Hodjegan A.

Drug Metab Dispos. 2016 Mar;44(3):476-80. doi: 10.1124/dmd.115.067777. Epub 2016 Feb 3.

PMID:
26842595
25.

In Vitro-In Vivo Extrapolation Scaling Factors for Intestinal P-Glycoprotein and Breast Cancer Resistance Protein: Part I: A Cross-Laboratory Comparison of Transporter-Protein Abundances and Relative Expression Factors in Human Intestine and Caco-2 Cells.

Harwood MD, Achour B, Neuhoff S, Russell MR, Carlson G, Warhurst G; Amin Rostami-Hodjegan.

Drug Metab Dispos. 2016 Mar;44(3):297-307. doi: 10.1124/dmd.115.067371. Epub 2015 Dec 2.

PMID:
26631742
26.

Translational value of liquid chromatography coupled with tandem mass spectrometry-based quantitative proteomics for in vitro-in vivo extrapolation of drug metabolism and transport and considerations in selecting appropriate techniques.

Al Feteisi H, Achour B, Rostami-Hodjegan A, Barber J.

Expert Opin Drug Metab Toxicol. 2015;11(9):1357-69. doi: 10.1517/17425255.2015.1055245. Epub 2015 Jun 26. Review.

PMID:
26108733
27.

Application of an LC-MS/MS method for the simultaneous quantification of human intestinal transporter proteins absolute abundance using a QconCAT technique.

Harwood MD, Achour B, Russell MR, Carlson GL, Warhurst G, Rostami-Hodjegan A.

J Pharm Biomed Anal. 2015 Jun 10;110:27-33. doi: 10.1016/j.jpba.2015.02.043. Epub 2015 Feb 28.

28.

Choice of LC-MS methods for the absolute quantification of drug-metabolizing enzymes and transporters in human tissue: a comparative cost analysis.

Al Feteisi H, Achour B, Barber J, Rostami-Hodjegan A.

AAPS J. 2015 Mar;17(2):438-46. doi: 10.1208/s12248-014-9712-6. Epub 2015 Feb 6.

29.

Meta-analysis of expression of hepatic organic anion-transporting polypeptide (OATP) transporters in cellular systems relative to human liver tissue.

Badée J, Achour B, Rostami-Hodjegan A, Galetin A.

Drug Metab Dispos. 2015 Apr;43(4):424-32. doi: 10.1124/dmd.114.062034. Epub 2015 Jan 6.

PMID:
25564656
30.

[Peripapillary changes detected by SD OCT in eyes in high myopia].

Chebil A, Ben Achour B, Maamouri R, Ben Abdallah M, El Matri L.

J Fr Ophtalmol. 2014 Oct;37(8):635-9. doi: 10.1016/j.jfo.2014.07.007. Epub 2014 Sep 6. French.

PMID:
25199484
31.

Protein expression of various hepatic uridine 5'-diphosphate glucuronosyltransferase (UGT) enzymes and their inter-correlations: a meta-analysis.

Achour B, Rostami-Hodjegan A, Barber J.

Biopharm Drug Dispos. 2014 Sep;35(6):353-61. doi: 10.1002/bdd.1906. Epub 2014 Aug 6.

PMID:
24931139
32.

Expression of hepatic drug-metabolizing cytochrome p450 enzymes and their intercorrelations: a meta-analysis.

Achour B, Barber J, Rostami-Hodjegan A.

Drug Metab Dispos. 2014 Aug;42(8):1349-56. doi: 10.1124/dmd.114.058834. Epub 2014 May 30.

PMID:
24879845
33.

[Choroidal thickness assessment with SD-OCT in high myopia with dome-shaped macula].

Chebil A, Ben Achour B, Chaker N, Jedidi L, Mghaieth F, El Matri L.

J Fr Ophtalmol. 2014 Mar;37(3):237-41. doi: 10.1016/j.jfo.2013.10.002. Epub 2014 Feb 20. French.

PMID:
24560943
34.

[Factors linked to foveoschisis in high myopia].

Chebil A, Ben Achour B, Chaker N, Bouladi M, Charfi H, El Matri L.

J Fr Ophtalmol. 2014 Feb;37(2):138-42. doi: 10.1016/j.jfo.2013.11.001. Epub 2014 Jan 31. French.

PMID:
24486073
35.

Simultaneous quantification of the abundance of several cytochrome P450 and uridine 5'-diphospho-glucuronosyltransferase enzymes in human liver microsomes using multiplexed targeted proteomics.

Achour B, Russell MR, Barber J, Rostami-Hodjegan A.

Drug Metab Dispos. 2014 Apr;42(4):500-10. doi: 10.1124/dmd.113.055632. Epub 2014 Jan 9.

PMID:
24408517
36.

Alternative fusion protein strategies to express recalcitrant QconCAT proteins for quantitative proteomics of human drug metabolizing enzymes and transporters.

Russell MR, Achour B, Mckenzie EA, Lopez R, Harwood MD, Rostami-Hodjegan A, Barber J.

J Proteome Res. 2013 Dec 6;12(12):5934-42. doi: 10.1021/pr400279u. Epub 2013 Oct 31.

PMID:
24124648
37.

The activities of Achromobacter lysyl endopeptidase and Lysobacter lysyl endoproteinase as digestive enzymes for quantitative proteomics.

Achour B, Barber J.

Rapid Commun Mass Spectrom. 2013 Jul 30;27(14):1669-72. doi: 10.1002/rcm.6612. No abstract available.

PMID:
23765612
38.

Analysis of the clinico-hematological relevance of the breakpoint location within M-BCR in chronic myeloid leukemia.

Bennour A, Ouahchi I, Achour B, Zaier M, Youssef YB, Khelif A, Saad A, Sennana H.

Med Oncol. 2013 Mar;30(1):348. doi: 10.1007/s12032-012-0348-z. Epub 2012 Dec 27.

PMID:
23269583
39.

Nasopharyngeal/nasal type NK/T lymphoma: analysis of 23 cases and current review of the literature.

Youssef YB, Bougmiza I, Bouabid Z, Achour B, Regaieg H, Sriha B, Belkadhi M, Omri HE, Khelif A.

Kulak Burun Bogaz Ihtis Derg. 2012 Sep-Oct;22(5):275-83. doi: 10.5606/kbbihtisas.2012.053. Review.

PMID:
22991988
40.

Cytochrome P450 Pig liver pie: determination of individual cytochrome P450 isoform contents in microsomes from two pig livers using liquid chromatography in conjunction with mass spectrometry [corrected].

Achour B, Barber J, Rostami-Hodjegan A.

Drug Metab Dispos. 2011 Nov;39(11):2130-4. doi: 10.1124/dmd.111.040618. Epub 2011 Jul 27. Erratum in: Drug Metab Dispos. 2012 Jan;40(1):227.

PMID:
21795467
41.

Triethylenetetramine-N,N,N',N",N"',N"'-hexaacetic Acid (TTHA) and TTHA-Bis(butanamide) as Chelating Agents Relevant to Radiopharmaceutical Applications.

Achour B, Costa J, Delgado R, Garrigues E, Geraldes CF, Korber N, Nepveu F, Prata MI.

Inorg Chem. 1998 Jun 1;37(11):2729-2740.

PMID:
11670409
42.

Triethylenetetramine-N,N,N',N'',N''',N'''-hexaacetic Acid (TTHA) and TTHA-Bis(butanamide) as Chelating Agents Relevant to Radiopharmaceutical Applications.

Achour B, Costa J, Delgado R, Garrigues E, Geraldes CF, Korber N, Nepveu F, Prata MI.

Inorg Chem. 1998 Dec 14;37(25):6552. doi: 10.1021/ic981268i. No abstract available.

PMID:
27362748

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