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Items: 38

1.

Choline Kinase Alpha Inhibition by EB-3D Triggers Cellular Senescence, Reduces Tumor Growth and Metastatic Dissemination in Breast Cancer.

Mariotto E, Viola G, Ronca R, Persano L, Aveic S, Bhujwalla ZM, Mori N, Accordi B, Serafin V, López-Cara LC, Bortolozzi R.

Cancers (Basel). 2018 Oct 22;10(10). pii: E391. doi: 10.3390/cancers10100391.

2.

USP7 Cooperates with NOTCH1 to Drive the Oncogenic Transcriptional Program in T-Cell Leukemia.

Jin Q, Martinez CA, Arcipowski KM, Zhu Y, Gutierrez-Diaz BT, Wang KK, Johnson MR, Volk AG, Wang F, Wu J, Grove C, Wang H, Sokirniy I, Thomas PM, Goo YA, Abshiru NA, Hijiya N, Peirs S, Vandamme N, Berx G, Goosens S, Marshall SA, Rendleman EJ, Takahashi YH, Wang L, Rawat R, Bartom ET, Collings CK, Van Vlierberghe P, Strikoudis A, Kelly S, Ueberheide B, Mantis C, Kandela I, Bourquin JP, Bornhauser B, Serafin V, Bresolin S, Paganin M, Accordi B, Basso G, Kelleher NL, Weinstock J, Kumar S, Crispino JD, Shilatifard A, Ntziachristos P.

Clin Cancer Res. 2019 Jan 1;25(1):222-239. doi: 10.1158/1078-0432.CCR-18-1740. Epub 2018 Sep 17.

PMID:
30224337
3.

Pre-clinical evaluation of second generation PIM inhibitors for the treatment of T-cell acute lymphoblastic leukemia and lymphoma.

De Smedt R, Peirs S, Morscio J, Matthijssens F, Roels J, Reunes L, Lintermans B, Goossens S, Lammens T, Van Roy N, Touzart A, Jenni S, Tsai YC, Lovisa F, Mussolin L, Serafin V, Van Nieuwerburgh F, Deforce D, Uyttebroeck A, Tousseyn T, Burkhardt B, Klapper W, De Moerloose B, Benoit Y, Macintyre E, Bourquin JP, Basso G, Accordi B, Bornhauser B, Meijerink J, Vandenberghe P, Van Vlierberghe P.

Haematologica. 2019 Jan;104(1):e17-e20. doi: 10.3324/haematol.2018.199257. Epub 2018 Aug 3. No abstract available.

4.

EB-3D a novel choline kinase inhibitor induces deregulation of the AMPK-mTOR pathway and apoptosis in leukemia T-cells.

Mariotto E, Bortolozzi R, Volpin I, Carta D, Serafin V, Accordi B, Basso G, Navarro PL, López-Cara LC, Viola G.

Biochem Pharmacol. 2018 Sep;155:213-223. doi: 10.1016/j.bcp.2018.07.004. Epub 2018 Jul 11.

PMID:
30006194
5.

Dual inhibition of PI3K/mTOR signaling in chemoresistant AML primary cells.

Bertacchini J, Frasson C, Chiarini F, D'Avella D, Accordi B, Anselmi L, Barozzi P, Forghieri F, Luppi M, Martelli AM, Basso G, Najmaldin S, Khosravi A, Rahim F, Marmiroli S.

Adv Biol Regul. 2018 May;68:2-9. doi: 10.1016/j.jbior.2018.03.001. Epub 2018 Mar 19.

PMID:
29576448
6.

Epigenetic heterogeneity affects the risk of relapse in children with t(8;21)RUNX1-RUNX1T1-rearranged AML.

Zampini M, Tregnago C, Bisio V, Simula L, Borella G, Manara E, Zanon C, Zonta F, Serafin V, Accordi B, Campello S, Buldini B, Pession A, Locatelli F, Basso G, Pigazzi M.

Leukemia. 2018 May;32(5):1124-1134. doi: 10.1038/s41375-017-0003-y. Epub 2018 Feb 2.

PMID:
29472719
7.

Ribociclib, a Cdk4/Cdk6 kinase inhibitor, enhances glucocorticoid sensitivity in B-acute lymphoblastic leukemia (B-All).

Bortolozzi R, Mattiuzzo E, Trentin L, Accordi B, Basso G, Viola G.

Biochem Pharmacol. 2018 Jul;153:230-241. doi: 10.1016/j.bcp.2018.01.050. Epub 2018 Feb 3.

PMID:
29408328
8.

Glucocorticoid resistance is reverted by LCK inhibition in pediatric T-cell acute lymphoblastic leukemia.

Serafin V, Capuzzo G, Milani G, Minuzzo SA, Pinazza M, Bortolozzi R, Bresolin S, Porcù E, Frasson C, Indraccolo S, Basso G, Accordi B.

Blood. 2017 Dec 21;130(25):2750-2761. doi: 10.1182/blood-2017-05-784603. Epub 2017 Nov 3.

9.

Phosphoproteomic analysis reveals hyperactivation of mTOR/STAT3 and LCK/Calcineurin axes in pediatric early T-cell precursor ALL.

Serafin V, Lissandron V, Buldini B, Bresolin S, Paganin M, Grillo F, Andriano N, Palmi C, Cazzaniga G, Marmiroli S, Conter V, Basso G, Accordi B.

Leukemia. 2017 Apr;31(4):1007-1011. doi: 10.1038/leu.2017.13. Epub 2017 Jan 13. No abstract available.

PMID:
28082737
10.

Profiling B cell chronic lymphocytic leukemia by reverse phase protein array: Focus on apoptotic proteins.

Frezzato F, Accordi B, Trimarco V, Gattazzo C, Martini V, Milani G, Bresolin S, Severin F, Visentin A, Basso G, Semenzato G, Trentin L.

J Leukoc Biol. 2016 Nov;100(5):1061-1070. Epub 2016 Jun 16.

PMID:
27312846
11.

Deciphering KRAS and NRAS mutated clone dynamics in MLL-AF4 paediatric leukaemia by ultra deep sequencing analysis.

Trentin L, Bresolin S, Giarin E, Bardini M, Serafin V, Accordi B, Fais F, Tenca C, De Lorenzo P, Valsecchi MG, Cazzaniga G, Kronnie GT, Basso G.

Sci Rep. 2016 Oct 4;6:34449. doi: 10.1038/srep34449.

12.

Annexin 2A sustains glioblastoma cell dissemination and proliferation.

Maule F, Bresolin S, Rampazzo E, Boso D, Della Puppa A, Esposito G, Porcù E, Mitola S, Lombardi G, Accordi B, Tumino M, Basso G, Persano L.

Oncotarget. 2016 Aug 23;7(34):54632-54649. doi: 10.18632/oncotarget.10565.

13.

Reversal of the glycolytic phenotype of primary effusion lymphoma cells by combined targeting of cellular metabolism and PI3K/Akt/ mTOR signaling.

Mediani L, Gibellini F, Bertacchini J, Frasson C, Bosco R, Accordi B, Basso G, Bonora M, Calabrò ML, Mattiolo A, Sgarbi G, Baracca A, Pinton P, Riva G, Rampazzo E, Petrizza L, Prodi L, Milani D, Luppi M, Potenza L, De Pol A, Cocco L, Capitani S, Marmiroli S.

Oncotarget. 2016 Feb 2;7(5):5521-37. doi: 10.18632/oncotarget.6315.

14.

Inhibition of PI3K Signalling Selectively Affects Medulloblastoma Cancer Stem Cells.

Frasson C, Rampazzo E, Accordi B, Beggio G, Pistollato F, Basso G, Persano L.

Biomed Res Int. 2015;2015:973912. doi: 10.1155/2015/973912. Epub 2015 Oct 18.

15.

Ex Vivo Signaling Protein Mapping in T Lymphocytes in the Psoriatic Arthritis Joints.

Fiocco U, Martini V, Accordi B, Caso F, Costa L, Oliviero F, Scanu A, Felicetti M, Frallonardo P, Facco M, Boso D, Molena B, Zambello R, Ramonda R, Cozzi F, Scarpa R, Basso G, Semenzato G, Dayer JM, Doria A, Punzi L.

J Rheumatol Suppl. 2015 Nov;93:48-52. doi: 10.3899/jrheum.150636.

PMID:
26523057
16.

Transcriptional network profile on synovial fluid T cells in psoriatic arthritis.

Fiocco U, Martini V, Accordi B, Caso F, Costa L, Oliviero F, Scanu A, Facco M, Boso D, Gatto M, Felicetti M, Frallonardo P, Ramonda R, Piva L, Zambello R, Agostini C, Scarpa R, Basso G, Semenzato G, Dayer JM, Punzi L, Doria A.

Clin Rheumatol. 2015 Sep;34(9):1571-80. doi: 10.1007/s10067-015-3002-2. Epub 2015 Jul 9.

PMID:
26152611
17.

Targeting BAG-1: a novel strategy to increase drug efficacy in acute myeloid leukemia.

Aveic S, Viola G, Accordi B, Micalizzi C, Santoro N, Masetti R, Locatelli F, Basso G, Pigazzi M.

Exp Hematol. 2015 Mar;43(3):180-190.e6. doi: 10.1016/j.exphem.2014.10.016. Epub 2014 Nov 11.

PMID:
25461257
18.

Development of a pluripotent stem cell derived neuronal model to identify chemically induced pathway perturbations in relation to neurotoxicity: effects of CREB pathway inhibition.

Pistollato F, Louisse J, Scelfo B, Mennecozzi M, Accordi B, Basso G, Gaspar JA, Zagoura D, Barilari M, Palosaari T, Sachinidis A, Bremer-Hoffmann S.

Toxicol Appl Pharmacol. 2014 Oct 15;280(2):378-88. doi: 10.1016/j.taap.2014.08.007. Epub 2014 Aug 19.

19.

A therapeutic approach to treat prostate cancer by targeting Nm23-H1/h-Prune interaction.

Carotenuto M, de Antonellis P, Chiarolla CM, Attanasio C, Damiani V, Boffa I, Aiese N, Pedone E, Accordi B, Basso G, Navas L, Imbimbo C, Zollo M.

Naunyn Schmiedebergs Arch Pharmacol. 2015 Feb;388(2):257-69. doi: 10.1007/s00210-014-1035-8. Epub 2014 Aug 20.

PMID:
25138575
20.

Interleukin-22 in the diagnosis of active chronic graft-versus-host disease in paediatric patients.

Tumino M, Serafin V, Accordi B, Spadini S, Forest C, Cortese G, Lissandron V, Marzollo A, Basso G, Messina C.

Br J Haematol. 2015 Jan;168(1):142-5. doi: 10.1111/bjh.13068. Epub 2014 Aug 7. No abstract available.

PMID:
25098229
21.

Low PKCα expression within the MRD-HR stratum defines a new subgroup of childhood T-ALL with very poor outcome.

Milani G, Rebora P, Accordi B, Galla L, Bresolin S, Cazzaniga G, Buldini B, Mura R, Ladogana S, Giraldi E, Conter V, Te Kronnie G, Valsecchi MG, Basso G.

Oncotarget. 2014 Jul 30;5(14):5234-45.

22.

Feedbacks and adaptive capabilities of the PI3K/Akt/mTOR axis in acute myeloid leukemia revealed by pathway selective inhibition and phosphoproteome analysis.

Bertacchini J, Guida M, Accordi B, Mediani L, Martelli AM, Barozzi P, Petricoin E 3rd, Liotta L, Milani G, Giordan M, Luppi M, Forghieri F, De Pol A, Cocco L, Basso G, Marmiroli S.

Leukemia. 2014 Nov;28(11):2197-205. doi: 10.1038/leu.2014.123. Epub 2014 Apr 4.

PMID:
24699302
23.

Differential expression of hERG1A and hERG1B genes in pediatric acute lymphoblastic leukemia identifies different prognostic subgroups.

Pillozzi S, Accordi B, Rebora P, Serafin V, Valsecchi MG, Basso G, Arcangeli A.

Leukemia. 2014 Jun;28(6):1352-5. doi: 10.1038/leu.2014.26. Epub 2014 Jan 16. No abstract available.

24.

JAK/STAT/PKCδ molecular pathways in synovial fluid T lymphocytes reflect the in vivo T helper-17 expansion in psoriatic arthritis.

Fiocco U, Accordi B, Martini V, Oliviero F, Facco M, Cabrelle A, Piva L, Molena B, Caso F, Costa L, Scanu A, Pagnin E, Atteno M, Scarpa R, Basso G, Semenzato G, Punzi L, Doria A, Dayer JM.

Immunol Res. 2014 Jan;58(1):61-9. doi: 10.1007/s12026-013-8481-0.

PMID:
24385089
25.

Neuroblastoma tumorigenesis is regulated through the Nm23-H1/h-Prune C-terminal interaction.

Carotenuto M, Pedone E, Diana D, de Antonellis P, Džeroski S, Marino N, Navas L, Di Dato V, Scoppettuolo MN, Cimmino F, Correale S, Pirone L, Monti SM, Bruder E, Zenko B, Slavkov I, Pastorino F, Ponzoni M, Schulte JH, Schramm A, Eggert A, Westermann F, Arrigoni G, Accordi B, Basso G, Saviano M, Fattorusso R, Zollo M.

Sci Rep. 2013;3:1351. doi: 10.1038/srep01351.

26.

AMPK inhibition enhances apoptosis in MLL-rearranged pediatric B-acute lymphoblastic leukemia cells.

Accordi B, Galla L, Milani G, Curtarello M, Serafin V, Lissandron V, Viola G, te Kronnie G, De Maria R, Petricoin EF 3rd, Liotta LA, Indraccolo S, Basso G.

Leukemia. 2013 Apr;27(5):1019-27. doi: 10.1038/leu.2012.338. Epub 2012 Nov 21.

PMID:
23228943
27.

Blockade of intra-articular TNF in peripheral spondyloarthritis: its relevance to clinical scores, quantitative imaging and synovial fluid and synovial tissue biomarkers.

Fiocco U, Sfriso P, Oliviero F, Lunardi F, Calabrese F, Scagliori E, Cozzi L, Di Maggio A, Nardacchione R, Molena B, Felicetti M, Gazzola K, Stramare R, Rubaltelli L, Accordi B, Costa L, Roux-Lombard P, Punzi L, Dayer JM.

Joint Bone Spine. 2013 Mar;80(2):165-70. doi: 10.1016/j.jbspin.2012.06.016. Epub 2012 Aug 3.

PMID:
22867975
28.

Synovial biomarkers in psoriatic arthritis.

Fiocco U, Oliviero F, Sfriso P, Calabrese F, Lunardi F, Scagliori E, Rubaltelli L, Stramare R, Di Maggio A, Nardacchione R, Cozzi L, Molena B, Felicetti M, Gazzola K, Lo Nigro A, Accordi B, Roux-Lombard P, Dayer JM, Punzi L.

J Rheumatol Suppl. 2012 Jul;89:61-4. doi: 10.3899/jrheum.120246.

PMID:
22751595
29.

Sox4 cooperates with CREB in myeloid transformation.

Sandoval S, Kraus C, Cho EC, Cho M, Bies J, Manara E, Accordi B, Landaw EM, Wolff L, Pigazzi M, Sakamoto KM.

Blood. 2012 Jul 5;120(1):155-65. doi: 10.1182/blood-2011-05-357418. Epub 2012 May 24.

30.

The micro-RNA 199b-5p regulatory circuit involves Hes1, CD15, and epigenetic modifications in medulloblastoma.

Andolfo I, Liguori L, De Antonellis P, Cusanelli E, Marinaro F, Pistollato F, Garzia L, De Vita G, Petrosino G, Accordi B, Migliorati R, Basso G, Iolascon A, Cinalli G, Zollo M.

Neuro Oncol. 2012 May;14(5):596-612. doi: 10.1093/neuonc/nos002. Epub 2012 Mar 12.

31.

Chemotherapy resistance in acute lymphoblastic leukemia requires hERG1 channels and is overcome by hERG1 blockers.

Pillozzi S, Masselli M, De Lorenzo E, Accordi B, Cilia E, Crociani O, Amedei A, Veltroni M, D'Amico M, Basso G, Becchetti A, Campana D, Arcangeli A.

Blood. 2011 Jan 20;117(3):902-14. doi: 10.1182/blood-2010-01-262691. Epub 2010 Nov 3.

32.

Functional protein network activation mapping reveals new potential molecular drug targets for poor prognosis pediatric BCP-ALL.

Accordi B, Espina V, Giordan M, VanMeter A, Milani G, Galla L, Ruzzene M, Sciro M, Trentin L, De Maria R, te Kronnie G, Petricoin E, Liotta L, Basso G.

PLoS One. 2010 Oct 21;5(10):e13552. doi: 10.1371/journal.pone.0013552.

33.

Hovering between death and life: natural apoptosis and phagocytes in the blastogenetic cycle of the colonial ascidian Botryllus schlosseri.

Cima F, Manni L, Basso G, Fortunato E, Accordi B, Schiavon F, Ballarin L.

Dev Comp Immunol. 2010 Mar;34(3):272-85. doi: 10.1016/j.dci.2009.10.005. Epub 2009 Oct 28.

PMID:
19837108
34.

Hepatocyte growth factor receptor c-MET is associated with FAS and when activated enhances drug-induced apoptosis in pediatric B acute lymphoblastic leukemia with TEL-AML1 translocation.

Accordi B, Pillozzi S, Dell'Orto MC, Cazzaniga G, Arcangeli A, Kronnie GT, Basso G.

J Biol Chem. 2007 Oct 5;282(40):29384-93. Epub 2007 Aug 2.

35.

Down-regulation of DLX3 expression in MLL-AF4 childhood lymphoblastic leukemias is mediated by promoter region hypermethylation.

Campo Dell'Orto M, Banelli B, Giarin E, Accordi B, Trentin L, Romani M, te Kronnie G, Basso G.

Oncol Rep. 2007 Aug;18(2):417-23.

PMID:
17611665
36.

Validation by RQ-PCR and flow cytometry of alpha-defensin1-3 (DEFA1-3) overexpression in relapsed and refractory acute lymphoblastic leukemia.

Te Kronnie G, Bicciato S, Franceschini L, Accordi B, Dellíorto MC, Rinaldi A, Pession A, Barisone E, Conter V, Locatelli F, Basso G.

Oncol Rep. 2006 Feb;15(2):341-6.

PMID:
16391852
37.

A leukemia-enriched cDNA microarray platform identifies new transcripts with relevance to the biology of pediatric acute lymphoblastic leukemia.

De Pittà C, Tombolan L, Campo Dell'Orto M, Accordi B, te Kronnie G, Romualdi C, Vitulo N, Basso G, Lanfranchi G.

Haematologica. 2005 Jul;90(7):890-8.

38.

[Center for the Study of the Geology of Central Italy, Rome].

Accordi B.

Ric Sci. 1970 Jul-Aug;40(4):312-3. Italian. No abstract available.

PMID:
5500903

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