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Items: 1 to 50 of 56

1.

Strategies to degrade estrogen receptor α in primary and ESR1 mutant-expressing metastatic breast cancer.

Busonero C, Leone S, Bartoloni S, Acconcia F.

Mol Cell Endocrinol. 2019 Jan 15;480:107-121. doi: 10.1016/j.mce.2018.10.020. Epub 2018 Oct 31. Review.

PMID:
30389467
2.

In silico screening for ERα down modulators identifies thioridazine as an anti-proliferative agent in primary, 4OH-tamoxifen-resistant and Y537S ERα-expressing breast cancer cells.

Busonero C, Leone S, Bianchi F, Acconcia F.

Cell Oncol (Dordr). 2018 Dec;41(6):677-686. doi: 10.1007/s13402-018-0400-x. Epub 2018 Sep 4.

PMID:
30182339
3.

A high throughput method to study the physiology of E2:ERα signaling in breast cancer cells.

Leone S, Busonero C, Acconcia F.

J Cell Physiol. 2018 May;233(5):3713-3722. doi: 10.1002/jcp.26251. Epub 2017 Nov 24.

PMID:
29091270
4.

A functional drug re-purposing screening identifies carfilzomib as a drug preventing 17β-estradiol: ERα signaling and cell proliferation in breast cancer cells.

Busonero C, Leone S, Klemm C, Acconcia F.

Mol Cell Endocrinol. 2018 Jan 15;460:229-237. doi: 10.1016/j.mce.2017.07.027. Epub 2017 Jul 29.

PMID:
28760601
5.

Emetine induces estrogen receptor alpha degradation and prevents 17β-estradiol-induced breast cancer cell proliferation.

Busonero C, Leone S, Acconcia F.

Cell Oncol (Dordr). 2017 Jun;40(3):299-301. doi: 10.1007/s13402-017-0322-z. Epub 2017 Mar 29. No abstract available.

PMID:
28357567
6.

Xenoestrogen regulation of ERα/ERβ balance in hormone-associated cancers.

Acconcia F, Fiocchetti M, Marino M.

Mol Cell Endocrinol. 2017 Dec 5;457:3-12. doi: 10.1016/j.mce.2016.10.033. Epub 2016 Nov 2. Review.

PMID:
27816767
7.

Selective binding of estrogen receptor α to ubiquitin chains.

Pesiri V, Di Muzio E, Polticelli F, Acconcia F.

IUBMB Life. 2016 Jul;68(7):569-77. doi: 10.1002/iub.1514. Epub 2016 May 18.

8.

Dynamin II is required for 17β-estradiol signaling and autophagy-based ERα degradation.

Totta P, Busonero C, Leone S, Marino M, Acconcia F.

Sci Rep. 2016 Mar 24;6:23727. doi: 10.1038/srep23727.

9.

Myosin VI Contains a Compact Structural Motif that Binds to Ubiquitin Chains.

He F, Wollscheid HP, Nowicka U, Biancospino M, Valentini E, Ehlinger A, Acconcia F, Magistrati E, Polo S, Walters KJ.

Cell Rep. 2016 Mar 22;14(11):2683-94. doi: 10.1016/j.celrep.2016.01.079. Epub 2016 Mar 10.

10.

Molecular Mechanisms of Action of BPA.

Acconcia F, Pallottini V, Marino M.

Dose Response. 2015 Oct 7;13(4):1559325815610582. doi: 10.1177/1559325815610582. eCollection 2015 Oct-Dec. Review.

11.

Modulation of 17β-Estradiol Signaling on Cellular Proliferation by Caveolin-2.

Totta P, Gionfra F, Busonero C, Acconcia F.

J Cell Physiol. 2016 Jun;231(6):1219-25. doi: 10.1002/jcp.25218. Epub 2015 Oct 23.

PMID:
26480297
12.

Estrogen receptor α L429 and A430 regulate 17β-estradiol-induced cell proliferation via CREB1.

Pesiri V, Totta P, Segatto M, Bianchi F, Pallottini V, Marino M, Acconcia F.

Cell Signal. 2015 Dec;27(12):2380-8. doi: 10.1016/j.cellsig.2015.08.021. Epub 2015 Sep 5.

PMID:
26348925
13.

Clathrin Heavy Chain Interacts With Estrogen Receptor α and Modulates 17β-Estradiol Signaling.

Totta P, Pesiri V, Enari M, Marino M, Acconcia F.

Mol Endocrinol. 2015 May;29(5):739-55. doi: 10.1210/me.2014-1385. Epub 2015 Apr 10.

14.

ERβ-dependent neuroglobin up-regulation impairs 17β-estradiol-induced apoptosis in DLD-1 colon cancer cells upon oxidative stress injury.

Fiocchetti M, Camilli G, Acconcia F, Leone S, Ascenzi P, Marino M.

J Steroid Biochem Mol Biol. 2015 May;149:128-37. doi: 10.1016/j.jsbmb.2015.02.005. Epub 2015 Feb 12.

PMID:
25683270
15.

Neuroglobin, a pro-survival player in estrogen receptor α-positive cancer cells.

Fiocchetti M, Nuzzo MT, Totta P, Acconcia F, Ascenzi P, Marino M.

Cell Death Dis. 2014 Oct 9;5:e1449. doi: 10.1038/cddis.2014.418.

16.

Ubiquitin-activating enzyme is necessary for 17β-estradiol-induced breast cancer cell proliferation and migration.

Pesiri V, Totta P, Marino M, Acconcia F.

IUBMB Life. 2014 Aug;66(8):578-85. doi: 10.1002/iub.1296. Epub 2014 Aug 19.

17.

Lysosomal function is involved in 17β-estradiol-induced estrogen receptor α degradation and cell proliferation.

Totta P, Pesiri V, Marino M, Acconcia F.

PLoS One. 2014 Apr 15;9(4):e94880. doi: 10.1371/journal.pone.0094880. eCollection 2014.

18.

Xenoestrogens alter estrogen receptor (ER) α intracellular levels.

La Rosa P, Pellegrini M, Totta P, Acconcia F, Marino M.

PLoS One. 2014 Feb 20;9(2):e88961. doi: 10.1371/journal.pone.0088961. eCollection 2014. Erratum in: PLoS One. 2014;9(5):e99379.

19.

Identification of an estrogen receptor α non covalent ubiquitin-binding surface: role in 17β-estradiol-induced transcriptional activity.

Pesiri V, La Rosa P, Stano P, Acconcia F.

J Cell Sci. 2013 Jun 15;126(Pt 12):2577-82. doi: 10.1242/jcs.123307. Epub 2013 Apr 16.

20.

Neuroglobin upregulation induced by 17β-estradiol sequesters cytocrome c in the mitochondria preventing H2O2-induced apoptosis of neuroblastoma cells.

De Marinis E, Fiocchetti M, Acconcia F, Ascenzi P, Marino M.

Cell Death Dis. 2013 Feb 21;4:e508. doi: 10.1038/cddis.2013.30.

21.

The naringenin-induced proapoptotic effect in breast cancer cell lines holds out against a high bisphenol a background.

Bulzomi P, Bolli A, Galluzzo P, Acconcia F, Ascenzi P, Marino M.

IUBMB Life. 2012 Aug;64(8):690-6. doi: 10.1002/iub.1049. Epub 2012 Jun 12.

22.

Palmitoylation regulates 17β-estradiol-induced estrogen receptor-α degradation and transcriptional activity.

La Rosa P, Pesiri V, Leclercq G, Marino M, Acconcia F.

Mol Endocrinol. 2012 May;26(5):762-74. doi: 10.1210/me.2011-1208. Epub 2012 Mar 22.

23.

Susceptibility of estrogen receptor rapid responses to xenoestrogens: Physiological outcomes.

Marino M, Pellegrini M, La Rosa P, Acconcia F.

Steroids. 2012 Aug;77(10):910-7. doi: 10.1016/j.steroids.2012.02.019. Epub 2012 Mar 5. Review.

PMID:
22410438
24.

Functional polymeric nanoparticles for dexamethasone loading and release.

Fratoddi I, Venditti I, Cametti C, Palocci C, Chronopoulou L, Marino M, Acconcia F, Russo MV.

Colloids Surf B Biointerfaces. 2012 May 1;93:59-66. doi: 10.1016/j.colsurfb.2011.12.008. Epub 2011 Dec 20.

PMID:
22227016
25.

HIV-1 Nef induces proinflammatory state in macrophages through its acidic cluster domain: involvement of TNF alpha receptor associated factor 2.

Mangino G, Percario ZA, Fiorucci G, Vaccari G, Acconcia F, Chiarabelli C, Leone S, Noto A, Horenkamp FA, Manrique S, Romeo G, Polticelli F, Geyer M, Affabris E.

PLoS One. 2011;6(8):e22982. doi: 10.1371/journal.pone.0022982. Epub 2011 Aug 23.

26.

Signaling functions of ubiquitin in the 17β-estradiol (E2):estrogen receptor (ER) α network.

La Rosa P, Acconcia F.

J Steroid Biochem Mol Biol. 2011 Nov;127(3-5):223-30. doi: 10.1016/j.jsbmb.2011.07.008. Epub 2011 Jul 30. Review.

PMID:
21824518
27.

The Effects of 17β-estradiol in Cancer are Mediated by Estrogen Receptor Signaling at the Plasma Membrane.

Acconcia F, Marino M.

Front Physiol. 2011 Jun 30;2:30. doi: 10.3389/fphys.2011.00030. eCollection 2011.

28.

The pro-apoptotic effect of quercetin in cancer cell lines requires ERβ-dependent signals.

Bulzomi P, Galluzzo P, Bolli A, Leone S, Acconcia F, Marino M.

J Cell Physiol. 2012 May;227(5):1891-8. doi: 10.1002/jcp.22917.

PMID:
21732360
29.

Nanostructured functional co-polymers bioconjugate integrin inhibitors.

Laganà A, Venditti I, Fratoddi I, Capriotti AL, Caruso G, Battocchio C, Polzonetti G, Acconcia F, Marino M, Russo MV.

J Colloid Interface Sci. 2011 Sep 15;361(2):465-71. doi: 10.1016/j.jcis.2011.05.041. Epub 2011 May 27.

PMID:
21669438
30.

17β-Estradiol-induced cell proliferation requires estrogen receptor (ER) α monoubiquitination.

La Rosa P, Pesiri V, Marino M, Acconcia F.

Cell Signal. 2011 Jul;23(7):1128-35. doi: 10.1016/j.cellsig.2011.02.006. Epub 2011 Feb 26.

PMID:
21356307
31.

17β-estradiol regulates estrogen receptor α monoubiquitination.

La Rosa P, Marino M, Acconcia F.

IUBMB Life. 2011 Jan;63(1):49-53. doi: 10.1002/iub.414.

32.

Bisphenol A impairs estradiol-induced protective effects against DLD-1 colon cancer cell growth.

Bolli A, Bulzomi P, Galluzzo P, Acconcia F, Marino M.

IUBMB Life. 2010 Sep;62(9):684-7. doi: 10.1002/iub.370.

33.

Naringenin and 17beta-estradiol coadministration prevents hormone-induced human cancer cell growth.

Bulzomi P, Bolli A, Galluzzo P, Leone S, Acconcia F, Marino M.

IUBMB Life. 2010 Jan;62(1):51-60. doi: 10.1002/iub.279.

34.

17beta-Estradiol regulates the first steps of skeletal muscle cell differentiation via ER-alpha-mediated signals.

Galluzzo P, Rastelli C, Bulzomi P, Acconcia F, Pallottini V, Marino M.

Am J Physiol Cell Physiol. 2009 Nov;297(5):C1249-62. doi: 10.1152/ajpcell.00188.2009. Epub 2009 Sep 2.

35.

Cortactin promotes migration and platelet-derived growth factor-induced actin reorganization by signaling to Rho-GTPases.

Lai FP, Szczodrak M, Oelkers JM, Ladwein M, Acconcia F, Benesch S, Auinger S, Faix J, Small JV, Polo S, Stradal TE, Rottner K.

Mol Biol Cell. 2009 Jul;20(14):3209-23. doi: 10.1091/mbc.E08-12-1180. Epub 2009 May 20.

36.

Ubiquitin in trafficking: the network at work.

Acconcia F, Sigismund S, Polo S.

Exp Cell Res. 2009 May 15;315(9):1610-8. doi: 10.1016/j.yexcr.2008.10.014. Epub 2008 Oct 28. Review.

PMID:
19007773
37.

Phosphorylation-dependent regulation of nuclear localization and functions of integrin-linked kinase.

Acconcia F, Barnes CJ, Singh RR, Talukder AH, Kumar R.

Proc Natl Acad Sci U S A. 2007 Apr 17;104(16):6782-7. Epub 2007 Apr 9.

38.

An inherent role of integrin-linked kinase-estrogen receptor alpha interaction in cell migration.

Acconcia F, Manavathi B, Mascarenhas J, Talukder AH, Mills G, Kumar R.

Cancer Res. 2006 Nov 15;66(22):11030-8.

39.

An inherent role of microtubule network in the action of nuclear receptor.

Manavathi B, Acconcia F, Rayala SK, Kumar R.

Proc Natl Acad Sci U S A. 2006 Oct 24;103(43):15981-6. Epub 2006 Oct 16.

40.

Nitric oxide impairs the 17beta-estradiol-induced apoptosis in human colon adenocarcinoma cells.

Marino M, Galluzzo P, Leone S, Acconcia F, Ascenzi P.

Endocr Relat Cancer. 2006 Jun;13(2):559-69.

PMID:
16728582
41.

Estrogen and tamoxifen induce cytoskeletal remodeling and migration in endometrial cancer cells.

Acconcia F, Barnes CJ, Kumar R.

Endocrinology. 2006 Mar;147(3):1203-12. Epub 2005 Dec 8.

PMID:
16339197
42.

S-palmitoylation modulates estrogen receptor alpha localization and functions.

Marino M, Ascenzi P, Acconcia F.

Steroids. 2006 Apr;71(4):298-303. Epub 2005 Nov 7. Review.

PMID:
16274718
43.

Daidzein-sulfate metabolites affect transcriptional and antiproliferative activities of estrogen receptor-beta in cultured human cancer cells.

Totta P, Acconcia F, Virgili F, Cassidy A, Weinberg PD, Rimbach G, Marino M.

J Nutr. 2005 Nov;135(11):2687-93.

PMID:
16251631
44.

Estrogen receptor signalling: bases for drug actions.

Marino M, Acconcia F, Ascenzi P.

Curr Drug Targets Immune Endocr Metabol Disord. 2005 Sep;5(3):305-14. Review.

PMID:
16178790
45.

Signaling regulation of genomic and nongenomic functions of estrogen receptors.

Acconcia F, Kumar R.

Cancer Lett. 2006 Jul 8;238(1):1-14. Epub 2005 Aug 3. Review.

PMID:
16084012
46.
47.

Palmitoylation-dependent estrogen receptor alpha membrane localization: regulation by 17beta-estradiol.

Acconcia F, Ascenzi P, Bocedi A, Spisni E, Tomasi V, Trentalance A, Visca P, Marino M.

Mol Biol Cell. 2005 Jan;16(1):231-7. Epub 2004 Oct 20.

48.

Survival versus apoptotic 17beta-estradiol effect: role of ER alpha and ER beta activated non-genomic signaling.

Acconcia F, Totta P, Ogawa S, Cardillo I, Inoue S, Leone S, Trentalance A, Muramatsu M, Marino M.

J Cell Physiol. 2005 Apr;203(1):193-201.

PMID:
15389627
49.

Rapid nongenomic effects of 3,5,3'-triiodo-L-thyronine on the intracellular pH of L-6 myoblasts are mediated by intracellular calcium mobilization and kinase pathways.

D'Arezzo S, Incerpi S, Davis FB, Acconcia F, Marino M, Farias RN, Davis PJ.

Endocrinology. 2004 Dec;145(12):5694-703. Epub 2004 Sep 2.

PMID:
15345678
50.

Nutritional flavonoids modulate estrogen receptor alpha signaling.

Virgili F, Acconcia F, Ambra R, Rinna A, Totta P, Marino M.

IUBMB Life. 2004 Mar;56(3):145-51.

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