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Items: 13


MM-131, a bispecific anti-Met/EpCAM mAb, inhibits HGF-dependent and HGF-independent Met signaling through concurrent binding to EpCAM.

Casaletto JB, Geddie ML, Abu-Yousif AO, Masson K, Fulgham A, Boudot A, Maiwald T, Kearns JD, Kohli N, Su S, Razlog M, Raue A, Kalra A, Håkansson M, Logan DT, Welin M, Chattopadhyay S, Harms BD, Nielsen UB, Schoeberl B, Lugovskoy AA, MacBeath G.

Proc Natl Acad Sci U S A. 2019 Apr 9;116(15):7533-7542. doi: 10.1073/pnas.1819085116. Epub 2019 Mar 21.


Immunocapture-LC/MS-Based Target Engagement Measurement in Tumor Plasma Membrane.

Sugimoto H, Ghosh D, Chen S, Smith MD, Abu-Yousif AO, Qian MG.

Anal Chem. 2018 Nov 20;90(22):13564-13571. doi: 10.1021/acs.analchem.8b03726. Epub 2018 Nov 9.


Dual-Isotope Cryoimaging Quantitative Autoradiography: Investigating Antibody-Drug Conjugate Distribution and Payload Delivery Through Imaging.

Ilovich O, Qutaish M, Hesterman JY, Orcutt K, Hoppin J, Polyak I, Seaman M, Abu-Yousif AO, Cvet D, Bradley DP.

J Nucl Med. 2018 Sep;59(9):1461-1466. doi: 10.2967/jnumed.118.207753. Epub 2018 May 4.


Photodynamic activation as a molecular switch to promote osteoblast cell differentiation via AP-1 activation.

Kushibiki T, Tu Y, Abu-Yousif AO, Hasan T.

Sci Rep. 2015 Aug 17;5:13114. doi: 10.1038/srep13114.


Selective treatment and monitoring of disseminated cancer micrometastases in vivo using dual-function, activatable immunoconjugates.

Spring BQ, Abu-Yousif AO, Palanisami A, Rizvi I, Zheng X, Mai Z, Anbil S, Sears RB, Mensah LB, Goldschmidt R, Erdem SS, Oliva E, Hasan T.

Proc Natl Acad Sci U S A. 2014 Mar 11;111(10):E933-42. doi: 10.1073/pnas.1319493111. Epub 2014 Feb 26.


Epidermal growth factor receptor-targeted photosensitizer selectively inhibits EGFR signaling and induces targeted phototoxicity in ovarian cancer cells.

Abu-Yousif AO, Moor AC, Zheng X, Savellano MD, Yu W, Selbo PK, Hasan T.

Cancer Lett. 2012 Aug 28;321(2):120-7. doi: 10.1016/j.canlet.2012.01.014. Epub 2012 Jan 18.


Killing hypoxic cell populations in a 3D tumor model with EtNBS-PDT.

Evans CL, Abu-Yousif AO, Park YJ, Klein OJ, Celli JP, Rizvi I, Zheng X, Hasan T.

PLoS One. 2011;6(8):e23434. doi: 10.1371/journal.pone.0023434. Epub 2011 Aug 18.


UVB radiation-induced β-catenin signaling is enhanced by COX-2 expression in keratinocytes.

Smith KA, Tong X, Abu-Yousif AO, Mikulec CC, Gottardi CJ, Fischer SM, Pelling JC.

Mol Carcinog. 2012 Sep;51(9):734-45. doi: 10.1002/mc.20840. Epub 2011 Aug 18.


Synergistic enhancement of carboplatin efficacy with photodynamic therapy in a three-dimensional model for micrometastatic ovarian cancer.

Rizvi I, Celli JP, Evans CL, Abu-Yousif AO, Muzikansky A, Pogue BW, Finkelstein D, Hasan T.

Cancer Res. 2010 Nov 15;70(22):9319-28. doi: 10.1158/0008-5472.CAN-10-1783. Epub 2010 Nov 9.


Quantitative imaging reveals heterogeneous growth dynamics and treatment-dependent residual tumor distributions in a three-dimensional ovarian cancer model.

Celli JP, Rizvi I, Evans CL, Abu-Yousif AO, Hasan T.

J Biomed Opt. 2010 Sep-Oct;15(5):051603. doi: 10.1117/1.3483903.


The ABC's of industry: a postdoc program provides a sneak peek into industry careers.

Abu-Yousif AO, Hett EC, Skoczenski AM, Hasan T.

Nat Biotechnol. 2010 Jun;28(6):625-6. doi: 10.1038/nbt0610-625. No abstract available.


PuraMatrix encapsulation of cancer cells.

Abu-Yousif AO, Rizvi I, Evans CL, Celli JP, Hasan T.

J Vis Exp. 2009 Dec 17;(34). pii: 1692. doi: 10.3791/1692.


Enhancement of UVB-induced apoptosis by apigenin in human keratinocytes and organotypic keratinocyte cultures.

Abu-Yousif AO, Smith KA, Getsios S, Green KJ, Van Dross RT, Pelling JC.

Cancer Res. 2008 Apr 15;68(8):3057-65. doi: 10.1158/0008-5472.CAN-07-2763.

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