Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 30

1.

Early Inhibition of Fatty Acid Synthesis Reduces Generation of Memory Precursor Effector T Cells in Chronic Infection.

Ibitokou SA, Dillon BE, Sinha M, Szczesny B, Delgadillo A, Reda Abdelrahman D, Szabo C, Abu-Elheiga L, Porter C, Tuvdendorj D, Stephens R.

J Immunol. 2018 Jan 15;200(2):643-656. doi: 10.4049/jimmunol.1602110. Epub 2017 Dec 13.

2.

Identification and Quantitation of Malonic Acid Biomarkers of In-Born Error Metabolism by Targeted Metabolomics.

Ambati CS, Yuan F, Abu-Elheiga LA, Zhang Y, Shetty V.

J Am Soc Mass Spectrom. 2017 May;28(5):929-938. doi: 10.1007/s13361-017-1631-1. Epub 2017 Mar 17.

PMID:
28315235
3.

Mislocalization and inhibition of acetyl-CoA carboxylase 1 by a synthetic small molecule.

Jung D, Abu-Elheiga L, Ayuzawa R, Gu Z, Shirakawa T, Fujiki Y, Nakatsuji N, Wakil SJ, Uesugi M.

Biochem J. 2012 Dec 15;448(3):409-16. doi: 10.1042/BJ20121158.

PMID:
23067267
4.

Acetyl-CoA carboxylase 2-/- mutant mice are protected against fatty liver under high-fat, high-carbohydrate dietary and de novo lipogenic conditions.

Abu-Elheiga L, Wu H, Gu Z, Bressler R, Wakil SJ.

J Biol Chem. 2012 Apr 6;287(15):12578-88. doi: 10.1074/jbc.M111.309559. Epub 2012 Feb 23.

5.

Synthesis and evaluation of diarylthiazole derivatives that inhibit activation of sterol regulatory element-binding proteins.

Kamisuki S, Shirakawa T, Kugimiya A, Abu-Elheiga L, Choo HY, Yamada K, Shimogawa H, Wakil SJ, Uesugi M.

J Med Chem. 2011 Jul 14;54(13):4923-7. doi: 10.1021/jm200304y. Epub 2011 Jun 8.

6.

Activation of nuclear receptor CAR ameliorates diabetes and fatty liver disease.

Dong B, Saha PK, Huang W, Chen W, Abu-Elheiga LA, Wakil SJ, Stevens RD, Ilkayeva O, Newgard CB, Chan L, Moore DD.

Proc Natl Acad Sci U S A. 2009 Nov 3;106(44):18831-6. doi: 10.1073/pnas.0909731106. Epub 2009 Oct 22.

7.

A small molecule that blocks fat synthesis by inhibiting the activation of SREBP.

Kamisuki S, Mao Q, Abu-Elheiga L, Gu Z, Kugimiya A, Kwon Y, Shinohara T, Kawazoe Y, Sato S, Asakura K, Choo HY, Sakai J, Wakil SJ, Uesugi M.

Chem Biol. 2009 Aug 28;16(8):882-92. doi: 10.1016/j.chembiol.2009.07.007.

8.

Fatty acid metabolism: target for metabolic syndrome.

Wakil SJ, Abu-Elheiga LA.

J Lipid Res. 2009 Apr;50 Suppl:S138-43. doi: 10.1194/jlr.R800079-JLR200. Epub 2008 Dec 1. Review.

9.

Reduced heart size and increased myocardial fuel substrate oxidation in ACC2 mutant mice.

Essop MF, Camp HS, Choi CS, Sharma S, Fryer RM, Reinhart GA, Guthrie PH, Bentebibel A, Gu Z, Shulman GI, Taegtmeyer H, Wakil SJ, Abu-Elheiga L.

Am J Physiol Heart Circ Physiol. 2008 Jul;295(1):H256-65. doi: 10.1152/ajpheart.91489.2007. Epub 2008 May 16.

10.

Continuous fat oxidation in acetyl-CoA carboxylase 2 knockout mice increases total energy expenditure, reduces fat mass, and improves insulin sensitivity.

Choi CS, Savage DB, Abu-Elheiga L, Liu ZX, Kim S, Kulkarni A, Distefano A, Hwang YJ, Reznick RM, Codella R, Zhang D, Cline GW, Wakil SJ, Shulman GI.

Proc Natl Acad Sci U S A. 2007 Oct 16;104(42):16480-5. Epub 2007 Oct 8.

11.

Liver-specific deletion of acetyl-CoA carboxylase 1 reduces hepatic triglyceride accumulation without affecting glucose homeostasis.

Mao J, DeMayo FJ, Li H, Abu-Elheiga L, Gu Z, Shaikenov TE, Kordari P, Chirala SS, Heird WC, Wakil SJ.

Proc Natl Acad Sci U S A. 2006 May 30;103(22):8552-7. Epub 2006 May 22.

12.

Mutant mice lacking acetyl-CoA carboxylase 1 are embryonically lethal.

Abu-Elheiga L, Matzuk MM, Kordari P, Oh W, Shaikenov T, Gu Z, Wakil SJ.

Proc Natl Acad Sci U S A. 2005 Aug 23;102(34):12011-6. Epub 2005 Aug 15.

13.

Glucose and fat metabolism in adipose tissue of acetyl-CoA carboxylase 2 knockout mice.

Oh W, Abu-Elheiga L, Kordari P, Gu Z, Shaikenov T, Chirala SS, Wakil SJ.

Proc Natl Acad Sci U S A. 2005 Feb 1;102(5):1384-9. Epub 2005 Jan 26.

14.

Acetyl-CoA carboxylase 2 mutant mice are protected against obesity and diabetes induced by high-fat/high-carbohydrate diets.

Abu-Elheiga L, Oh W, Kordari P, Wakil SJ.

Proc Natl Acad Sci U S A. 2003 Sep 2;100(18):10207-12. Epub 2003 Aug 14.

15.

Fatty acid synthesis is essential in embryonic development: fatty acid synthase null mutants and most of the heterozygotes die in utero.

Chirala SS, Chang H, Matzuk M, Abu-Elheiga L, Mao J, Mahon K, Finegold M, Wakil SJ.

Proc Natl Acad Sci U S A. 2003 May 27;100(11):6358-63. Epub 2003 May 8.

16.

Continuous fatty acid oxidation and reduced fat storage in mice lacking acetyl-CoA carboxylase 2.

Abu-Elheiga L, Matzuk MM, Abo-Hashema KA, Wakil SJ.

Science. 2001 Mar 30;291(5513):2613-6.

17.

The subcellular localization of acetyl-CoA carboxylase 2.

Abu-Elheiga L, Brinkley WR, Zhong L, Chirala SS, Woldegiorgis G, Wakil SJ.

Proc Natl Acad Sci U S A. 2000 Feb 15;97(4):1444-9.

18.

Human acetyl-CoA carboxylase 2. Molecular cloning, characterization, chromosomal mapping, and evidence for two isoforms.

Abu-Elheiga L, Almarza-Ortega DB, Baldini A, Wakil SJ.

J Biol Chem. 1997 Apr 18;272(16):10669-77.

19.

Human fatty acid synthase: properties and molecular cloning.

Jayakumar A, Tai MH, Huang WY, al-Feel W, Hsu M, Abu-Elheiga L, Chirala SS, Wakil SJ.

Proc Natl Acad Sci U S A. 1995 Sep 12;92(19):8695-9.

20.

Human acetyl-CoA carboxylase: characterization, molecular cloning, and evidence for two isoforms.

Abu-Elheiga L, Jayakumar A, Baldini A, Chirala SS, Wakil SJ.

Proc Natl Acad Sci U S A. 1995 Apr 25;92(9):4011-5.

21.

Isolation and chromosomal mapping of genomic clones encoding the human fatty acid synthase gene.

Jayakumar A, Chirala SS, Chinault AC, Baldini A, Abu-Elheiga L, Wakil SJ.

Genomics. 1994 Sep 15;23(2):420-4.

PMID:
7835891
22.

Antigenic determinants of the 70-kDa subunit of the Ku autoantigen.

Abu-Elheiga L, Yaneva M.

Clin Immunol Immunopathol. 1992 Aug;64(2):145-52.

PMID:
1379527
23.

Effect of sinefungin on macromolecular biosynthesis and cell cycle of Plasmodium falciparum.

Messika E, Golenser J, Abu-Elheiga L, Robert-Gero M, Lederer E, Bachrach U.

Trop Med Parasitol. 1990 Sep;41(3):273-8.

PMID:
2255844
24.

Effect of polyamines on the activity of malarial alpha-like DNA polymerase.

Bachrach U, Abu-Elheiga L.

Eur J Biochem. 1990 Aug 17;191(3):633-7.

25.

Plasmodium falciparum: properties of an alpha-like DNA polymerase, the key enzyme in DNA synthesis.

Abu-Elheiga L, Spira DT, Bachrach U.

Exp Parasitol. 1990 Jul;71(1):21-6.

PMID:
2113008
26.

Polyamines in the cell cycle of the malarial parasite Plasmodium falciparum.

Bachrach U, Abu-Elheiga L, Assaraf YG, Golenser J, Spira DT.

Adv Exp Med Biol. 1988;250:643-50. No abstract available.

PMID:
3076343
27.
28.
29.
30.

Polyamines and the growth of leishmanial parasites.

Bachrach U, Abu-Elheiga L, Talmi M, Schnur LF, El-On J, Greenblatt CL.

Med Biol. 1981 Dec;59(5-6):441-7.

PMID:
7339304

Supplemental Content

Loading ...
Support Center