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Items: 1 to 50 of 188

1.

Clinical findings and outcomes of uveitis associated with multiple sclerosis.

AlBloushi AF, Dheyab AM, Al-Swaina NF, Al-Obailan M, Daif AK, Abu El-Asrar AM.

Eur J Ophthalmol. 2020 Feb 4:1120672120904667. doi: 10.1177/1120672120904667. [Epub ahead of print]

PMID:
32019337
2.

The Proinflammatory and Proangiogenic Macrophage Migration Inhibitory Factor Is a Potential Regulator in Proliferative Diabetic Retinopathy.

Abu El-Asrar AM, Ahmad A, Siddiquei MM, De Zutter A, Allegaert E, Gikandi PW, De Hertogh G, Van Damme J, Opdenakker G, Struyf S.

Front Immunol. 2019 Dec 4;10:2752. doi: 10.3389/fimmu.2019.02752. eCollection 2019.

3.

Soluble cytokine receptor levels in aqueous humour of patients with specific autoimmune uveitic entities: sCD30 is a biomarker of granulomatous uveitis.

Abu El-Asrar AM, Berghmans N, Al-Obeidan SA, Gikandi PW, Opdenakker G, Van Damme J, Struyf S.

Eye (Lond). 2019 Dec 5. doi: 10.1038/s41433-019-0693-7. [Epub ahead of print]

PMID:
31804623
4.

Phenotypic delineation of the retinal arterial macroaneurysms with supravalvular pulmonic stenosis syndrome.

Alkuraya H, Patel N, Ibrahim N, Al Ghamdi B, Alsulaiman SM, Nowilaty SR, Abboud E, Alturki R, Alkharashi A, Eyaid W, Almasseri Z, Alzaidan H, Alotaibi MD, Abu El-Asrar AM, Alamro B, Helaby R, Elshaer A, Almontashiri NAM, Al-Hussaini AA, Alkuraya FS.

Clin Genet. 2020 Mar;97(3):447-456. doi: 10.1111/cge.13676. Epub 2019 Dec 2.

PMID:
31730227
5.

Incidence, Risk Factors and Surgical Outcomes of Cataract among Patients with Vogt-Koyanagi-Harada Disease.

AlBloushi AF, Alfawaz AM, AlZaid A, Alsalamah AK, Gikandi PW, Abu El-Asrar AM.

Ocul Immunol Inflamm. 2019 Oct 22:1-9. doi: 10.1080/09273948.2019.1668430. [Epub ahead of print]

PMID:
31638886
6.

Postpartum Endogenous Candida Endophthalmitis.

AlBloushi AF, Almousa AN, Alkheraiji NF, Abu El-Asrar AM.

Middle East Afr J Ophthalmol. 2019 Aug 26;26(2):110-113. doi: 10.4103/meajo.MEAJO_284_18. eCollection 2019 Apr-Jun.

7.

Interleukin-11 Overexpression and M2 Macrophage Density are Associated with Angiogenic Activity in Proliferative Diabetic Retinopathy.

Abu El-Asrar AM, Ahmad A, Allegaert E, Siddiquei MM, Gikandi PW, De Hertogh G, Opdenakker G.

Ocul Immunol Inflamm. 2019 Aug 12:1-14. doi: 10.1080/09273948.2019.1616772. [Epub ahead of print]

PMID:
31403827
8.

Galectin-1 studies in proliferative diabetic retinopathy.

Abu El-Asrar AM, Ahmad A, Allegaert E, Siddiquei MM, Alam K, Gikandi PW, De Hertogh G, Opdenakker G.

Acta Ophthalmol. 2020 Feb;98(1):e1-e12. doi: 10.1111/aos.14191. Epub 2019 Jul 18.

PMID:
31318490
9.

Local Cytokine Expression Profiling in Patients with Specific Autoimmune Uveitic Entities.

Abu El-Asrar AM, Berghmans N, Al-Obeidan SA, Gikandi PW, Opdenakker G, Van Damme J, Struyf S.

Ocul Immunol Inflamm. 2019 Jun 4:1-10. doi: 10.1080/09273948.2019.1604974. [Epub ahead of print]

PMID:
31161935
10.

Cross-Talk between Sirtuin 1 and the Proinflammatory Mediator High-Mobility Group Box-1 in the Regulation of Blood-Retinal Barrier Breakdown in Diabetic Retinopathy.

Mohammad G, Abdelaziz GM, Siddiquei MM, Ahmad A, De Hertogh G, Abu El-Asrar AM.

Curr Eye Res. 2019 Oct;44(10):1133-1143. doi: 10.1080/02713683.2019.1625406. Epub 2019 Jun 14.

PMID:
31136205
11.

Retinal vessel oxygen saturation is affected in uveitis associated with Vogt-Koyanagi-Harada disease.

Abu El-Asrar AM, AlBloushi AF, Gikandi PW, Hardarson SH, Stefánsson E.

Br J Ophthalmol. 2019 Dec;103(12):1695-1699. doi: 10.1136/bjophthalmol-2018-313719. Epub 2019 Feb 23.

PMID:
30798260
12.

Expression of interleukin (IL)-10 family cytokines in aqueous humour of patients with specific endogenous uveitic entities: elevated levels of IL-19 in human leucocyte antigen-B27-associated uveitis.

Abu El-Asrar AM, Berghmans N, Al-Obeidan SA, Gikandi PW, Opdenakker G, Van Damme J, Struyf S.

Acta Ophthalmol. 2019 Aug;97(5):e780-e784. doi: 10.1111/aos.14039. Epub 2019 Feb 13.

PMID:
30761764
13.

Pediatric open-globe injury in a university-based tertiary hospital.

AlDahash F, Mousa A, Gikandi PW, Abu El-Asrar AM.

Eur J Ophthalmol. 2020 Mar;30(2):269-274. doi: 10.1177/1120672118818013. Epub 2018 Dec 12.

PMID:
30539664
14.

The CC chemokines CCL8, CCL13 and CCL20 are local inflammatory biomarkers of HLA-B27-associated uveitis.

Abu El-Asrar AM, Berghmans N, Al-Obeidan SA, Gikandi PW, Opdenakker G, Van Damme J, Struyf S.

Acta Ophthalmol. 2019 Feb;97(1):e122-e128. doi: 10.1111/aos.13835. Epub 2018 Sep 21.

15.

Incidence, Risk Factors and Surgical Outcomes of Cataract among Patients with Uveitis in a University Referral Hospital in Riyadh, Saudi Arabia.

AlBloushi AF, Alfawaz AM, Al-Dahmash SA, Al Owaifeer AM, AlEnezi SH, Al-Fakhri AS, Gikandi PW, Abu El-Asrar AM.

Ocul Immunol Inflamm. 2019;27(7):1105-1113. doi: 10.1080/09273948.2018.1504970. Epub 2018 Aug 24.

PMID:
30142008
16.

Catching the therapeutic window of opportunity in early initial-onset Vogt-Koyanagi-Harada uveitis can cure the disease.

Herbort CP Jr, Abu El Asrar AM, Takeuchi M, Pavésio CE, Couto C, Hedayatfar A, Maruyama K, Rao X, Silpa-Archa S, Somkijrungroj T.

Int Ophthalmol. 2019 Jun;39(6):1419-1425. doi: 10.1007/s10792-018-0949-4. Epub 2018 Jun 11. Review.

PMID:
29948499
17.

The Poly(ADP-Ribose)Polymerase-1 Inhibitor 1,5-Isoquinolinediol Attenuate Diabetes-Induced NADPH Oxidase-Derived Oxidative Stress in Retina.

Mohammad G, Alrashed SH, Almater AI, Siddiquei MM, Abu El-Asrar AM.

J Ocul Pharmacol Ther. 2018 Sep;34(7):512-520. doi: 10.1089/jop.2017.0117. Epub 2018 Jun 18.

PMID:
29912609
18.

Neutrophils and Activated Macrophages Control Mucosal Immunity by Proteolytic Cleavage of Antileukoproteinase.

Vandooren J, Goeminne P, Boon L, Ugarte-Berzal E, Rybakin V, Proost P, Abu El-Asrar AM, Opdenakker G.

Front Immunol. 2018 May 28;9:1154. doi: 10.3389/fimmu.2018.01154. eCollection 2018.

19.

Matrix metalloproteinase-14 is a biomarker of angiogenic activity in proliferative diabetic retinopathy.

Abu El-Asrar AM, Mohammad G, Allegaert E, Ahmad A, Siddiquei MM, Alam K, Gikandi PW, De Hertogh G, Opdenakker G.

Mol Vis. 2018 May 18;24:394-406. eCollection 2018.

20.

Rho-Associated Protein Kinase-1 Mediates the Regulation of Inflammatory Markers in Diabetic Retina and in Retinal Müller Cells.

Mohammad G, AlSharif HM, Siddiquei MM, Ahmad A, Alam K, Abu El-Asrar AM.

Ann Clin Lab Sci. 2018 Mar;48(2):137-145.

PMID:
29678838
21.

Presumed tuberculous uveitis in a university-based tertiary referral center in Saudi Arabia.

Al-Qarni A, Abouammoh MA, Almousa AN, Mousa A, Abu El-Asrar AM.

Int Ophthalmol. 2019 Feb;39(2):317-333. doi: 10.1007/s10792-017-0815-9. Epub 2018 Jan 9.

PMID:
29318438
22.

Association of HMGB1 with oxidative stress markers and regulators in PDR.

Abu El-Asrar AM, Alam K, Garcia-Ramirez M, Ahmad A, Siddiquei MM, Mohammad G, Mousa A, De Hertogh G, Opdenakker G, Simó R.

Mol Vis. 2017 Dec 5;23:853-871. eCollection 2017.

23.

Association of 150-kDa oxygen-regulated protein with vascular endothelial growth factor in proliferative diabetic retinopathy.

Abu El-Asrar AM, Ahmad A, Alam K, Bittoun E, Siddiquei MM, Mohammad G, Mousa A, De Hertogh G, Opdenakker G.

Acta Ophthalmol. 2018 Jun;96(4):e460-e467. doi: 10.1111/aos.13600. Epub 2017 Nov 2.

24.

Unbalanced Vitreous Levels of Osteoprotegerin, RANKL, RANK, and TRAIL in Proliferative Diabetic Retinopathy.

Abu El-Asrar AM, Ahmad A, Alam K, Bittoun E, Siddiquei MM, Mohammad G, Mousa A, De Hertogh G, Opdenakker G.

Ocul Immunol Inflamm. 2018;26(8):1248-1260. doi: 10.1080/09273948.2017.1343855. Epub 2017 Sep 15.

PMID:
28914577
25.

Prophylactic intravitreal antibiotics reduce the risk of post-traumatic endophthalmitis after repair of open globe injuries.

Abouammoh MA, Al-Mousa A, Gogandi M, Al-Mezaine H, Osman E, Alsharidah AM, Al-Kharashi A, Abu El-Asrar AM.

Acta Ophthalmol. 2018 May;96(3):e361-e365. doi: 10.1111/aos.13531. Epub 2017 Aug 3.

26.

Osteoprotegerin Is a New Regulator of Inflammation and Angiogenesis in Proliferative Diabetic Retinopathy.

Abu El-Asrar AM, Struyf S, Mohammad G, Gouwy M, Rytinx P, Siddiquei MM, Hernández C, Alam K, Mousa A, De Hertogh G, Opdenakker G, Simó R.

Invest Ophthalmol Vis Sci. 2017 Jun 1;58(7):3189-3201. doi: 10.1167/iovs.16-20993.

PMID:
28654984
27.

Differential expression and localization of human tissue inhibitors of metalloproteinases in proliferative diabetic retinopathy.

Abu El-Asrar AM, Ahmad A, Bittoun E, Siddiquei MM, Mohammad G, Mousa A, De Hertogh G, Opdenakker G.

Acta Ophthalmol. 2018 Feb;96(1):e27-e37. doi: 10.1111/aos.13451. Epub 2017 Apr 9.

28.

Extracellular matrix metalloproteinase inducer (EMMPRIN) is a potential biomarker of angiogenesis in proliferative diabetic retinopathy.

Abu El-Asrar AM, Ahmad A, Alam K, Siddiquei MM, Mohammad G, Hertogh G, Mousa A, Opdenakker G.

Acta Ophthalmol. 2017 Nov;95(7):697-704. doi: 10.1111/aos.13284. Epub 2016 Nov 18.

29.

Myeloid-Related Protein-14/MRP-14/S100A9/Calgranulin B is Associated with Inflammation in Proliferative Diabetic Retinopathy.

Abu El-Asrar AM, Alam K, Siddiquei MM, Van den Eynde K, Mohammad G, De Hertogh G, Opdenakker G.

Ocul Immunol Inflamm. 2018;26(4):615-624. doi: 10.1080/09273948.2016.1245759. Epub 2016 Nov 16.

PMID:
27849448
30.

Reappraisal of the management of Vogt-Koyanagi-Harada disease: sunset glow fundus is no more a fatality.

Herbort CP Jr, Abu El Asrar AM, Yamamoto JH, Pavésio CE, Gupta V, Khairallah M, Tugal-Tutkun I, Soheilian M, Takeuchi M, Papadia M.

Int Ophthalmol. 2017 Dec;37(6):1383-1395. doi: 10.1007/s10792-016-0395-0. Epub 2016 Nov 14. Review.

31.

The Cytokine Interleukin-6 and the Chemokines CCL20 and CXCL13 Are Novel Biomarkers of Specific Endogenous Uveitic Entities.

Abu El-Asrar AM, Berghmans N, Al-Obeidan SA, Mousa A, Opdenakker G, Van Damme J, Struyf S.

Invest Ophthalmol Vis Sci. 2016 Sep 1;57(11):4606-13. doi: 10.1167/iovs.16-19758.

PMID:
27603722
32.

High-Mobility Group Box-1 Protein Mediates the Regulation of Signal Transducer and Activator of Transcription-3 in the Diabetic Retina and in Human Retinal Müller Cells.

Mohammad G, Jomar D, Siddiquei MM, Alam K, Abu El-Asrar AM.

Ophthalmic Res. 2017;57(3):150-160. doi: 10.1159/000448115. Epub 2016 Aug 25.

PMID:
27560926
33.
34.

Upregulation of Thrombin/Matrix Metalloproteinase-1/Protease-Activated Receptor-1 Chain in Proliferative Diabetic Retinopathy.

Abu El-Asrar AM, Alam K, Nawaz MI, Mohammad G, Van den Eynde K, Siddiquei MM, Mousa A, De Hertogh G, Opdenakker G.

Curr Eye Res. 2016 Dec;41(12):1590-1600. Epub 2016 Jun 3.

PMID:
27261371
35.

Coexpression of heparanase activity, cathepsin L, tissue factor, tissue factor pathway inhibitor, and MMP-9 in proliferative diabetic retinopathy.

Abu El-Asrar AM, Siddiquei MM, Nawaz MI, De Hertogh G, Mohammad G, Alam K, Mousa A, Opdenakker G.

Mol Vis. 2016 Apr 30;22:424-35. eCollection 2016.

36.

Chronic Recurrent Vogt-Koyanagi-Harada Disease and Development of 'Sunset Glow Fundus' Predict Worse Retinal Sensitivity.

Abu El-Asrar AM, Al Mudhaiyan T, Al Najashi AA, Hemachandran S, Hariz R, Mousa A, Al-Muammar A.

Ocul Immunol Inflamm. 2017 Aug;25(4):475-485. doi: 10.3109/09273948.2016.1139730. Epub 2016 Mar 22.

PMID:
27003480
37.

Endothelial-to-mesenchymal transition contributes to the myofibroblast population in proliferative diabetic retinopathy.

Abu El-Asrar AM.

Saudi J Ophthalmol. 2016 Jan-Mar;30(1):1-2. doi: 10.1016/j.sjopt.2016.01.005. Epub 2016 Feb 16. No abstract available.

38.

Indocyanine green angiographic findings in initial-onset acute Vogt-Koyanagi-Harada disease.

Abouammoh MA, Gupta V, Hemachandran S, Herbort CP, Abu El-Asrar AM.

Acta Ophthalmol. 2016 Sep;94(6):573-8. doi: 10.1111/aos.12974. Epub 2016 Jan 29.

39.

Upregulated Expression of Heparanase in the Vitreous of Patients With Proliferative Diabetic Retinopathy Originates From Activated Endothelial Cells and Leukocytes.

Abu El-Asrar AM, Alam K, Nawaz MI, Mohammad G, Van den Eynde K, Siddiquei MM, Mousa A, De Hertogh G, Geboes K, Opdenakker G.

Invest Ophthalmol Vis Sci. 2015 Dec;56(13):8239-47. doi: 10.1167/iovs.15-18025.

PMID:
26720478
40.

Incidence and Risk Factors for Developing Glaucoma Among Patients with Uveitis in a University-based Tertiary Referral Center in Riyadh, Saudi Arabia.

Al Rubaie K, Al Dhahri H, Al Fawaz A, Hemachandran S, Mousa A, Mohamed AG, Al-Obeidan SA, Abu El-Asrar AM.

Ocul Immunol Inflamm. 2016 Oct;24(5):571-8. doi: 10.3109/09273948.2015.1047036. Epub 2015 Oct 15.

PMID:
26470690
41.

Mutual enhancement between high-mobility group box-1 and NADPH oxidase-derived reactive oxygen species mediates diabetes-induced upregulation of retinal apoptotic markers.

Mohammad G, Alam K, Nawaz MI, Siddiquei MM, Mousa A, Abu El-Asrar AM.

J Physiol Biochem. 2015 Sep;71(3):359-72. doi: 10.1007/s13105-015-0416-x. Epub 2015 Jun 4.

PMID:
26040511
42.

The Chemokine Platelet Factor-4 Variant (PF-4var)/CXCL4L1 Inhibits Diabetes-Induced Blood-Retinal Barrier Breakdown.

Abu El-Asrar AM, Mohammad G, Nawaz MI, Abdelsaid M, Siddiquei MM, Alam K, Van den Eynde K, De Hertogh G, Opdenakker G, Al-Shabrawey M, Van Damme J, Struyf S.

Invest Ophthalmol Vis Sci. 2015 Feb 24;56(3):1956-64. doi: 10.1167/iovs.14-16144.

43.

The tumor necrosis factor superfamily members TWEAK, TNFSF15 and fibroblast growth factor-inducible protein 14 are upregulated in proliferative diabetic retinopathy.

Abu El-Asrar AM, De Hertogh G, Nawaz MI, Siddiquei MM, Van den Eynde K, Mohammad G, Opdenakker G, Geboes K.

Ophthalmic Res. 2015;53(3):122-30. doi: 10.1159/000369300. Epub 2015 Feb 7.

PMID:
25676319
44.

Myofibroblasts in proliferative diabetic retinopathy can originate from infiltrating fibrocytes and through endothelial-to-mesenchymal transition (EndoMT).

Abu El-Asrar AM, De Hertogh G, van den Eynde K, Alam K, Van Raemdonck K, Opdenakker G, Van Damme J, Geboes K, Struyf S.

Exp Eye Res. 2015 Mar;132:179-89. doi: 10.1016/j.exer.2015.01.023. Epub 2015 Jan 28.

PMID:
25637870
45.

Vitreous hemorrhage in pediatric age group.

AlHarkan DH, Kahtani ES, Gikandi PW, Abu El-Asrar AM.

J Ophthalmol. 2014;2014:497083. doi: 10.1155/2014/497083. Epub 2014 Nov 19.

46.

Expression of bioactive lysophospholipids and processing enzymes in the vitreous from patients with proliferative diabetic retinopathy.

Abu El-Asrar AM, Nawaz MI, Mohammad G, Siddiquei MM, Alam K, Mousa A, Opdenakker G.

Lipids Health Dis. 2014 Dec 11;13:187. doi: 10.1186/1476-511X-13-187.

47.

High-Mobility Group Box-1 Modulates the Expression of Inflammatory and Angiogenic Signaling Pathways in Diabetic Retina.

Abu El-Asrar AM, Mohammad G, Nawaz MI, Siddiquei MM.

Curr Eye Res. 2015;40(11):1141-52. doi: 10.3109/02713683.2014.982829. Epub 2014 Dec 11.

PMID:
25495026
48.

Diabetic retinopathy and its risk factors in a society with a type 2 diabetes epidemic: a Saudi National Diabetes Registry-based study.

Al-Rubeaan K, Abu El-Asrar AM, Youssef AM, Subhani SN, Ahmad NA, Al-Sharqawi AH, Alguwaihes A, Alotaibi MS, Al-Ghamdi A, Ibrahim HM.

Acta Ophthalmol. 2015 Mar;93(2):e140-7. doi: 10.1111/aos.12532. Epub 2014 Oct 1.

49.

S100A4 is upregulated in proliferative diabetic retinopathy and correlates with markers of angiogenesis and fibrogenesis.

Abu El-Asrar AM, Nawaz MI, De Hertogh G, Alam K, Siddiquei MM, Van den Eynde K, Mousa A, Mohammad G, Geboes K, Opdenakker G.

Mol Vis. 2014 Sep 10;20:1209-24. eCollection 2014.

50.

Is systemic infliximab therapy effective for retinal cavernous hemangioma?

Alsulaiman SM, Abouammoh MA, Al-Dahmash SA, Abu El-Asrar AM.

Saudi Med J. 2014 Sep;35(9):1127-30.

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