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Items: 33

1.

Combinatorial detection of autoreactive CD8+ T cells with HLA-A2 multimers: a multi-centre study by the Immunology of Diabetes Society T Cell Workshop.

James EA, Abreu JRF, McGinty JW, Odegard JM, Fillié YE, Hocter CN, Culina S, Ladell K, Price DA, Alkanani A, Rihanek M, Fitzgerald-Miller L, Skowera A, Speake C, Gottlieb P, Davidson HW, Wong FS, Roep B, Mallone R; Immunology of Diabetes Society T Cell Workshop Committee.

Diabetologia. 2018 Mar;61(3):658-670. doi: 10.1007/s00125-017-4508-8. Epub 2017 Dec 1.

PMID:
29196783
2.

Immunological Balance Is Associated with Clinical Outcome after Autologous Hematopoietic Stem Cell Transplantation in Type 1 Diabetes.

Malmegrim KC, de Azevedo JT, Arruda LC, Abreu JR, Couri CE, de Oliveira GL, Palma PV, Scortegagna GT, Stracieri AB, Moraes DA, Dias JB, Pieroni F, Cunha R, Guilherme L, Santos NM, Foss MC, Covas DT, Burt RK, Simões BP, Voltarelli JC, Roep BO, Oliveira MC.

Front Immunol. 2017 Feb 22;8:167. doi: 10.3389/fimmu.2017.00167. eCollection 2017.

3.

Targeting proinsulin-reactive CD8+ T cells: a new direction for type 1 diabetes treatment.

Abreu JR, Roep BO.

Expert Rev Clin Immunol. 2013 Nov;9(11):1001-3. doi: 10.1586/1744666X.2013.852958. No abstract available.

PMID:
24168405
4.

Alternative splicing and differential expression of the islet autoantigen IGRP between pancreas and thymus contributes to immunogenicity of pancreatic islets but not diabetogenicity in humans.

de Jong VM, Abreu JR, Verrijn Stuart AA, van der Slik AR, Verhaeghen K, Engelse MA, Blom B, Staal FJ, Gorus FK, Roep BO.

Diabetologia. 2013 Dec;56(12):2651-8. doi: 10.1007/s00125-013-3034-6. Epub 2013 Sep 13.

PMID:
24030068
5.

Immune monitoring of islet and pancreas transplant recipients.

Abreu JR, Roep BO.

Curr Diab Rep. 2013 Oct;13(5):704-12. doi: 10.1007/s11892-013-0399-3. Review.

PMID:
23943207
6.

Plasmid-encoded proinsulin preserves C-peptide while specifically reducing proinsulin-specific CD8⁺ T cells in type 1 diabetes.

Roep BO, Solvason N, Gottlieb PA, Abreu JRF, Harrison LC, Eisenbarth GS, Yu L, Leviten M, Hagopian WA, Buse JB, von Herrath M, Quan J, King RS, Robinson WH, Utz PJ, Garren H; BHT-3021 Investigators, Steinman L.

Sci Transl Med. 2013 Jun 26;5(191):191ra82. doi: 10.1126/scitranslmed.3006103.

7.

Genetically engineered human islets protected from CD8-mediated autoimmune destruction in vivo.

Zaldumbide A, Alkemade G, Carlotti F, Nikolic T, Abreu JR, Engelse MA, Skowera A, de Koning EJ, Peakman M, Roep BO, Hoeben RC, Wiertz EJ.

Mol Ther. 2013 Aug;21(8):1592-601. doi: 10.1038/mt.2013.105. Epub 2013 May 21.

8.

Islet-specific CTL cloned from a type 1 diabetes patient cause beta-cell destruction after engraftment into HLA-A2 transgenic NOD/scid/IL2RG null mice.

Unger WW, Pearson T, Abreu JR, Laban S, van der Slik AR, der Kracht SM, Kester MG, Serreze DV, Shultz LD, Griffioen M, Drijfhout JW, Greiner DL, Roep BO.

PLoS One. 2012;7(11):e49213. doi: 10.1371/journal.pone.0049213. Epub 2012 Nov 14.

9.

CD8 T cell autoreactivity to preproinsulin epitopes with very low human leucocyte antigen class I binding affinity.

Abreu JR, Martina S, Verrijn Stuart AA, Fillié YE, Franken KL, Drijfhout JW, Roep BO.

Clin Exp Immunol. 2012 Oct;170(1):57-65. doi: 10.1111/j.1365-2249.2012.04635.x.

10.

Improved automated screening of diabetic retinopathy.

Oliveira CM, Cristóvão LM, Ribeiro ML, Abreu JR.

Ophthalmologica. 2011;226(4):191-7. doi: 10.1159/000330285. Epub 2011 Aug 25.

PMID:
21865671
11.

Discovery of low-affinity preproinsulin epitopes and detection of autoreactive CD8 T-cells using combinatorial MHC multimers.

Unger WW, Velthuis J, Abreu JR, Laban S, Quinten E, Kester MG, Reker-Hadrup S, Bakker AH, Duinkerken G, Mulder A, Franken KL, Hilbrands R, Keymeulen B, Peakman M, Ossendorp F, Drijfhout JW, Schumacher TN, Roep BO.

J Autoimmun. 2011 Nov;37(3):151-9. doi: 10.1016/j.jaut.2011.05.012. Epub 2011 Jun 1.

PMID:
21636247
12.

Independent patterns of damage to retinocortical pathways in multiple sclerosis without a previous episode of optic neuritis.

Reis A, Mateus C, Macário MC, de Abreu JR, Castelo-Branco M.

J Neurol. 2011 Sep;258(9):1695-704. doi: 10.1007/s00415-011-6008-y. Epub 2011 Mar 31.

PMID:
21451995
13.

Silencing the expression of Ras family GTPase homologues decreases inflammation and joint destruction in experimental arthritis.

de Launay D, Vreijling J, Hartkamp LM, Karpus ON, Abreu JR, van Maanen MA, Sanders ME, Grabiec AM, Hamann J, Ørum H, Vervoordeldonk MJ, Fluiter K, Tak PP, Reedquist KA.

Am J Pathol. 2010 Dec;177(6):3010-24. doi: 10.2353/ajpath.2010.091053. Epub 2010 Oct 22.

14.

Photodynamic therapy with verteporfin in polypoidal choroidal vasculopathy: results after 3 years of follow-up.

Leal S, Silva R, Figueira J, Cachulo ML, Pires I, de Abreu JR, Cunha-Vaz JG.

Retina. 2010 Sep;30(8):1197-205. doi: 10.1097/IAE.0b013e3181d37486.

PMID:
20827139
15.

Sustained T cell Rap1 signaling is protective in the collagen-induced arthritis model of rheumatoid arthritis.

Abreu JR, Krausz S, Dontje W, Grabiec AM, de Launay D, Nolte MA, Tak PP, Reedquist KA.

Arthritis Rheum. 2010 Nov;62(11):3289-99. doi: 10.1002/art.27656.

16.

Simultaneous detection of circulating autoreactive CD8+ T-cells specific for different islet cell-associated epitopes using combinatorial MHC multimers.

Velthuis JH, Unger WW, Abreu JR, Duinkerken G, Franken K, Peakman M, Bakker AH, Reker-Hadrup S, Keymeulen B, Drijfhout JW, Schumacher TN, Roep BO.

Diabetes. 2010 Jul;59(7):1721-30. doi: 10.2337/db09-1486. Epub 2010 Mar 31.

17.

A Rac1 inhibitory peptide suppresses antibody production and paw swelling in the murine collagen-induced arthritis model of rheumatoid arthritis.

Abreu JR, Dontje W, Krausz S, de Launay D, van Hennik PB, van Stalborch AM, Ten Klooster JP, Sanders ME, Reedquist KA, Vervoordeldonk MJ, Hordijk PL, Tak PP.

Arthritis Res Ther. 2010;12(1):R2. doi: 10.1186/ar2900. Epub 2010 Jan 6.

18.

The Ras guanine nucleotide exchange factor RasGRF1 promotes matrix metalloproteinase-3 production in rheumatoid arthritis synovial tissue.

Abreu JR, de Launay D, Sanders ME, Grabiec AM, van de Sande MG, Tak PP, Reedquist KA.

Arthritis Res Ther. 2009;11(4):R121. doi: 10.1186/ar2785. Epub 2009 Aug 13.

19.

The presumed hyporesponsive behavior of rheumatoid arthritis T lymphocytes can be attributed to spontaneous ex vivo apoptosis rather than defects in T cell receptor signaling.

Abreu JR, Grabiec AM, Krausz S, Spijker R, Burakowski T, Maslinski W, Eldering E, Tak PP, Reedquist KA.

J Immunol. 2009 Jul 1;183(1):621-30. doi: 10.4049/jimmunol.0803278. Epub 2009 Jun 12.

20.

Short-term efficacy and safety of intravitreal ranibizumab for myopic choroidal neovascularization.

Silva RM, Ruiz-Moreno JM, Nascimento J, Carneiro A, Rosa P, Barbosaa A, Carvalheira F, Abreu JR, Cunha-Vaz JG.

Retina. 2008 Oct;28(8):1117-23.

PMID:
18788102
21.

Chorioretinal anastomosis and photodynamic therapy: a two-year follow-up study.

Silva RM, Cachulo ML, Figueira J, de Abreu JR, Cunha-Vaz JG.

Graefes Arch Clin Exp Ophthalmol. 2007 Aug;245(8):1131-9.

PMID:
17226019
22.

Bilateral CNV associated with optic nerve drusen treated with photodynamic therapy with verteporfin.

Silva R, Torrent T, Loureiro R, Travassos A, de Abreu JR.

Eur J Ophthalmol. 2004 Sep-Oct;14(5):434-7.

PMID:
15506607
23.

[Behavioral characteristics of the only child vs first-born and children with siblings].

Tavares MB, Fuchs FC, Diligenti F, de Abreu JR, Rohde LA, Fuchs SC.

Braz J Psychiatry. 2004 Mar;26(1):17-23. Epub 2004 Mar 30. Portuguese.

24.
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26.

Progression of retinopathy and alteration of the blood-retinal barrier in patients with type 2 diabetes: a 7-year prospective follow-up study.

Cunha-Vaz J, Lobo C, Sousa JC, Oliveiros B, Leite E, de Abreu JR.

Graefes Arch Clin Exp Ophthalmol. 1998 Apr;236(4):264-8.

PMID:
9561358
27.

The blood-retinal barrier in diabetes during puberty.

de Abreu JR, Silva R, Cunha-Vaz JG.

Arch Ophthalmol. 1994 Oct;112(10):1334-8.

PMID:
7945036
28.

Blood-retinal barrier permeability and its relation to progression of retinopathy in patients with type 2 diabetes. A four-year follow-up study.

Cunha-Vaz J, Leite E, Sousa JC, de Abreu JR.

Graefes Arch Clin Exp Ophthalmol. 1993 Mar;231(3):141-5.

PMID:
8462885
29.

Effect of calcium dobesilate on the blood-retinal barrier in early diabetic retinopathy.

Leite EB, Mota MC, de Abreu JR, Cunha-Vaz JG.

Int Ophthalmol. 1990 Mar;14(2):81-8.

PMID:
2187006
30.

[Giant cell tumor with regional lymph node metastasis].

Scharfe U, Wünschmann D, Abreu JR, Ribas E.

Zentralbl Chir. 1988;113(22):1496-500. German. No abstract available.

PMID:
3213303
31.

Effect of sorbinil on blood-retinal barrier in early diabetic retinopathy.

Cunha-Vaz JG, Mota CC, Leite EC, Abreu JR, Ruas MA.

Diabetes. 1986 May;35(5):574-8.

PMID:
3514333
32.

Effect of sulindac on the permeability of the blood-retinal barrier in early diabetic retinopathy.

Cunha-Vaz JG, Mota CC, Leite EC, Abreu JR, Ruas MA.

Arch Ophthalmol. 1985 Sep;103(9):1307-11.

PMID:
2931063
33.

Studies on retinal blood flow. II. Diabetic retinopathy.

Cunha-Vaz JG, Fonseca JR, de Abreu JR, Lima JJ.

Arch Ophthalmol. 1978 May;96(5):809-11.

PMID:
655916

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