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Items: 1 to 50 of 115

1.

Chimeric siRNAs with chemically modified pentofuranose and hexopyranose nucleotides: altritol-nucleotide (ANA) containing GalNAc-siRNA conjugates: in vitro and in vivo RNAi activity and resistance to 5'-exonuclease.

Kumar P, Degaonkar R, Guenther DC, Abramov M, Schepers G, Capobianco M, Jiang Y, Harp J, Kaittanis C, Janas MM, Castoreno A, Zlatev I, Schlegel MK, Herdewijn P, Egli M, Manoharan M.

Nucleic Acids Res. 2020 Mar 14. pii: gkaa125. doi: 10.1093/nar/gkaa125. [Epub ahead of print]

PMID:
32170309
2.

In Vivo Expression of Genetic Information from Phosphoramidate-DNA.

Nguyen H, Abramov M, Eremeeva E, Herdewijn P.

Chembiochem. 2020 Jan 15;21(1-2):272-278. doi: 10.1002/cbic.201900712.

PMID:
31868979
3.

Increasing telomerase enhanced steroidogenic genes expression and steroid hormones production in rat and human granulosa cells and in mouse ovary.

Mordechai A, Wasserman M, Abramov M, Ben-Menahem D, Har-Vardi I, Levitas E, Priel E.

J Steroid Biochem Mol Biol. 2020 Mar;197:105551. doi: 10.1016/j.jsbmb.2019.105551. Epub 2019 Nov 22.

PMID:
31765696
4.

[Reverse remodelling of the heart after atrial fibrillation ablation in patients with heart failure with reduced ejection fraction].

Gasimova NZ, Mikhaylov EN, Orshanskaya VS, Kamenev AV, Tatarsky RB, Abramov ML, Naymushin MA, Lebedeva VK, Vander MA, Garkina SV, Simonova KA, Lebedev DS.

Kardiologiia. 2019 Sep 16;59(8S):37-43. doi: 10.18087/cardio.2671. Russian.

PMID:
31526360
5.

Speech as an Unusual Presentation of Catatonia.

Abramov M, Mahgoub YO.

Prim Care Companion CNS Disord. 2019 Aug 8;21(4). pii: 18l02411. doi: 10.4088/PCC.18l02411. No abstract available.

6.

Highly stable hexitol based XNA aptamers targeting the vascular endothelial growth factor.

Eremeeva E, Fikatas A, Margamuljana L, Abramov M, Schols D, Groaz E, Herdewijn P.

Nucleic Acids Res. 2019 Jun 4;47(10):4927-4939. doi: 10.1093/nar/gkz252.

7.

Kinetic analysis of N-alkylaryl carboxamide hexitol nucleotides as substrates for evolved polymerases.

Renders M, Dumbre S, Abramov M, Kestemont D, Margamuljana L, Largy E, Cozens C, Vandenameele J, Pinheiro VB, Toye D, Frère JM, Herdewijn P.

Nucleic Acids Res. 2019 Mar 18;47(5):2160-2168. doi: 10.1093/nar/gkz008.

8.

Random-sequence genetic oligomer pools display an innate potential for ligation and recombination.

Mutschler H, Taylor AI, Porebski BT, Lightowlers A, Houlihan G, Abramov M, Herdewijn P, Holliger P.

Elife. 2018 Nov 21;7. pii: e43022. doi: 10.7554/eLife.43022.

9.

Methylated Nucleobases: Synthesis and Evaluation for Base Pairing In Vitro and In Vivo.

Jabgunde AM, Jaziri F, Bande O, Froeyen M, Abramov M, Nguyen H, Schepers G, Lescrinier E, Pinheiro VB, Pezo V, Marlière P, Herdewijn P.

Chemistry. 2018 Aug 27;24(48):12695-12707. doi: 10.1002/chem.201802304. Epub 2018 Jul 23.

PMID:
29883012
10.

XNA ligation using T4 DNA ligase in crowding conditions.

Kestemont D, Renders M, Leonczak P, Abramov M, Schepers G, Pinheiro VB, Rozenski J, Herdewijn P.

Chem Commun (Camb). 2018 Jun 14;54(49):6408-6411. doi: 10.1039/c8cc02414f.

PMID:
29872779
11.

Modulation of BACE1 Activity by Chemically Modified Aptamers.

Gasse C, Zaarour M, Noppen S, Abramov M, Marlière P, Liekens S, De Strooper B, Herdewijn P.

Chembiochem. 2018 Apr 4;19(7):754-763. doi: 10.1002/cbic.201700461. Epub 2018 Feb 19.

PMID:
29327496
12.

Enzymatic Incorporation of Modified Purine Nucleotides in DNA.

Abu El Asrar R, Margamuljana L, Abramov M, Bande O, Agnello S, Jang M, Herdewijn P.

Chembiochem. 2017 Dec 14;18(24):2408-2415. doi: 10.1002/cbic.201700393. Epub 2017 Nov 14.

PMID:
29024251
13.

A phase III trial comparing oral S-1/cisplatin and intravenous 5-fluorouracil/cisplatin in patients with untreated diffuse gastric cancer.

Ajani JA, Abramov M, Bondarenko I, Shparyk Y, Gorbunova V, Hontsa A, Otchenash N, Alsina M, Lazarev S, Feliu J, Elme A, Esko V, Abdalla K, Verma U, Benedetti F, Aoyama T, Mizuguchi H, Makris L, Rosati G; DIGEST Study Group.

Ann Oncol. 2017 Sep 1;28(9):2142-2148. doi: 10.1093/annonc/mdx275.

14.

Base-Modified Nucleic Acids as a Powerful Tool for Synthetic Biology and Biotechnology.

Eremeeva E, Abramov M, Margamuljana L, Herdewijn P.

Chemistry. 2017 Jul 18;23(40):9560-9576. doi: 10.1002/chem.201700679. Epub 2017 Jun 27.

PMID:
28513881
15.

Hydrogel microarray for detection of polymorphisms in the UGT1A1, DPYD, GSTP1 and ABCB1 genes.

Heydarov R, Titov S, Abramov M, Timofeev E, Mikhailovich V.

Cancer Biomark. 2017;18(3):265-272. doi: 10.3233/CBM-160165.

PMID:
28085011
16.

The 5-chlorouracil:7-deazaadenine base pair as an alternative to the dT:dA base pair.

Eremeeva E, Abramov M, Marlière P, Herdewijn P.

Org Biomol Chem. 2016 Dec 20;15(1):168-176.

PMID:
27918055
17.
18.

Chemical Morphing of DNA Containing Four Noncanonical Bases.

Eremeeva E, Abramov M, Margamuljana L, Rozenski J, Pezo V, Marlière P, Herdewijn P.

Angew Chem Int Ed Engl. 2016 Jun 20;55(26):7515-9. doi: 10.1002/anie.201601529. Epub 2016 May 9.

PMID:
27159019
19.

Molecular simulation of cyclohexanyl nucleic acid (CNA) duplexes with CNA, DNA and RNA and CNA triloop and tetraloop hairpin structures.

Froeyen M, Abu el Asrar R, Abramov M, Herdewijn P.

Bioorg Med Chem. 2016 Apr 15;24(8):1778-85. doi: 10.1016/j.bmc.2016.03.007. Epub 2016 Mar 3.

PMID:
26968651
20.

NMR study on the interaction of the conserved CREX 'stem-loop' in the Hepatitis E virus genome with a naphthyridine-based ligand.

Dyubankova N, Froeyen M, Abramov M, Mattelaer HP, Herdewijn P, Lescrinier E.

Org Biomol Chem. 2015 Oct 7;13(37):9665-72. doi: 10.1039/c5ob01381j.

PMID:
26264660
21.

Achiral, acyclic nucleic acids: synthesis and biophysical studies of a possible prebiotic polymer.

Srivastava P, Abou El Asrar R, Knies C, Abramov M, Froeyen M, Rozenski J, Rosemeyer H, Herdewijn P.

Org Biomol Chem. 2015 Sep 21;13(35):9249-60. doi: 10.1039/c5ob00898k. Epub 2015 Jul 31.

PMID:
26228702
22.

Sulfonate derived phosphoramidates as active intermediates in the enzymatic primer-extension of DNA.

De S, Groaz E, Margamuljana L, Abramov M, Marlière P, Herdewijn P.

Org Biomol Chem. 2015 Apr 7;13(13):3950-62. doi: 10.1039/c5ob00157a.

PMID:
25719514
23.

Biatrial tachycardia following linear anterior wall ablation for the perimitral reentry: incidence and electrophysiological evaluations.

Mikhaylov EN, Mitrofanova LB, Vander MA, Tatarskiy RB, Kamenev AV, Abramov ML, Szili-Torok T, Lebedev DS.

J Cardiovasc Electrophysiol. 2015 Jan;26(1):28-35. doi: 10.1111/jce.12543. Epub 2014 Oct 20.

PMID:
25215599
24.

Overuse injuries of the foot: imaging presentations of common pathologies.

Abramov M, Stock H.

Conn Med. 2013 Nov-Dec;77(10):599-602.

PMID:
24367843
25.

Effects of six-membered carbohydrate rings on structure, stability, and kinetics of G-quadruplexes.

Zhou J, Abramov M, Liu F, Amrane S, Bourdoncle A, Herdewijn P, Mergny JL.

Chemistry. 2013 Oct 18;19(43):14719-25. doi: 10.1002/chem.201301743. Epub 2013 Sep 11.

PMID:
24027098
26.

Binary genetic cassettes for selecting XNA-templated DNA synthesis in vivo.

Pezo V, Liu FW, Abramov M, Froeyen M, Herdewijn P, Marlière P.

Angew Chem Int Ed Engl. 2013 Jul 29;52(31):8139-43. doi: 10.1002/anie.201303288. Epub 2013 Jun 26. No abstract available.

PMID:
23804524
27.
28.

Structure, stability and function of 5-chlorouracil modified A:U and G:U base pairs.

Patra A, Harp J, Pallan PS, Zhao L, Abramov M, Herdewijn P, Egli M.

Nucleic Acids Res. 2013 Feb 1;41(4):2689-97. doi: 10.1093/nar/gks1316. Epub 2012 Dec 28.

29.

Microarray with LNA-probes for genotyping of polymorphic variants of Gilbert's syndrome gene UGT1A1(TA)n.

Fesenko EE, Heydarov RN, Stepanova EV, Abramov ME, Chudinov AV, Zasedatelev AS, Mikhailovich VM.

Clin Chem Lab Med. 2013 Jun;51(6):1177-84. doi: 10.1515/cclm-2012-0656.

PMID:
23241680
30.

Synthetic genetic polymers capable of heredity and evolution.

Pinheiro VB, Taylor AI, Cozens C, Abramov M, Renders M, Zhang S, Chaput JC, Wengel J, Peak-Chew SY, McLaughlin SH, Herdewijn P, Holliger P.

Science. 2012 Apr 20;336(6079):341-4. doi: 10.1126/science.1217622.

31.

Solution structure and conformational dynamics of deoxyxylonucleic acids (dXNA): an orthogonal nucleic acid candidate.

Maiti M, Siegmund V, Abramov M, Lescrinier E, Rosemeyer H, Froeyen M, Ramaswamy A, Ceulemans A, Marx A, Herdewijn P.

Chemistry. 2012 Jan 16;18(3):869-79. doi: 10.1002/chem.201102509. Epub 2011 Dec 16.

PMID:
22180030
32.

[Effectiveness of DNA repair and expression of MLH1, MSH2 and FASR in lymphocytes of patients with chemotherapy-responsive, disseminated cutaneous melanoma].

Tronov VA, Artamonov DN, Abramov ME, Gorbacheva LB, Lichinitser MR.

Vopr Onkol. 2011;57(2):165-72. Russian.

PMID:
21809660
34.

Ablation of left atrial tachycardia with cycle length alternans after atrial fibrillation ablation: significance of fractionated electrogram mapping.

Mikhaylov E, Szili-Torok T, Abramov M, Lebedev D.

J Electrocardiol. 2011 Mar-Apr;44(2):164-70. doi: 10.1016/j.jelectrocard.2010.11.002. Epub 2010 Dec 18.

PMID:
21168148
35.

Outcome of anatomic ganglionated plexi ablation to treat paroxysmal atrial fibrillation: a 3-year follow-up study.

Mikhaylov E, Kanidieva A, Sviridova N, Abramov M, Gureev S, Szili-Torok T, Lebedev D.

Europace. 2011 Mar;13(3):362-70. doi: 10.1093/europace/euq416. Epub 2010 Nov 17.

PMID:
21088001
36.

Crystallization and preliminary X-ray study of the D-altritol oligonucleotide GTGTACAC.

Ovaere M, Van Aerschot A, Abramov M, Herdewijn P, Van Meervelt L.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Apr 1;66(Pt 4):460-2. doi: 10.1107/S1744309110007050. Epub 2010 Mar 31.

37.

Synthesis of 2'-N-formamido nucleosides and biological evaluation.

Abramov M, Renders M, Herdewijn P.

Nucleosides Nucleotides Nucleic Acids. 2009 Nov;28(11):1042-50. doi: 10.1080/15257770903362164.

PMID:
20183572
38.

Biological effects of hexitol and altritol-modified siRNAs targeting B-Raf.

Fisher M, Abramov M, Van Aerschot A, Rozenski J, Dixit V, Juliano RL, Herdewijn P.

Eur J Pharmacol. 2009 Mar 15;606(1-3):38-44. doi: 10.1016/j.ejphar.2009.01.030. Epub 2009 Jan 30.

39.

Polymerase-catalysed incorporation of glucose nucleotides into a DNA duplex.

Renders M, Abramov M, Froeyen M, Herdewijn P.

Chemistry. 2009;15(22):5463-70. doi: 10.1002/chem.200801951.

PMID:
19308979
40.

A large-scale chemical modification screen identifies design rules to generate siRNAs with high activity, high stability and low toxicity.

Bramsen JB, Laursen MB, Nielsen AF, Hansen TB, Bus C, Langkjaer N, Babu BR, Højland T, Abramov M, Van Aerschot A, Odadzic D, Smicius R, Haas J, Andree C, Barman J, Wenska M, Srivastava P, Zhou C, Honcharenko D, Hess S, Müller E, Bobkov GV, Mikhailov SN, Fava E, Meyer TF, Chattopadhyaya J, Zerial M, Engels JW, Herdewijn P, Wengel J, Kjems J.

Nucleic Acids Res. 2009 May;37(9):2867-81. doi: 10.1093/nar/gkp106. Epub 2009 Mar 12.

41.

Dendritic nucleotides: interaction with an aliphatic acid monolayer.

Wang G, Abramov M, Van Aerschot A, Rozenski J, Lei S, Klymchenko A, Van der Auweraer M, De Feyter S, Herdewijn P.

Chem Biodivers. 2008 Sep;5(9):1675-82. doi: 10.1002/cbdv.200890156.

PMID:
18816520
42.

Synthesis of altritol nucleoside phosphoramidites for oligonucleotide synthesis.

Abramov M, Herdewijn P.

Curr Protoc Nucleic Acid Chem. 2007 Sep;Chapter 1:Unit 1.18. doi: 10.1002/0471142700.nc0118s30.

PMID:
18428966
43.

HNA and ANA high-affinity arrays for detections of DNA and RNA single-base mismatches.

Abramov M, Schepers G, Van Aerschot A, Van Hummelen P, Herdewijn P.

Biosens Bioelectron. 2008 Jun 15;23(11):1728-32. doi: 10.1016/j.bios.2008.01.033. Epub 2008 Feb 13.

PMID:
18378134
44.

Inhibition of MDR1 expression with altritol-modified siRNAs.

Fisher M, Abramov M, Van Aerschot A, Xu D, Juliano RL, Herdewijn P.

Nucleic Acids Res. 2007;35(4):1064-74. Epub 2007 Jan 30.

45.
46.

Synthesis of D-altritol nucleosides with a 3'-O-tert-butyldimethylsilyl protecting group.

Abramov M, Marchand A, Calleja-Marchand A, Herdewijn P.

Nucleosides Nucleotides Nucleic Acids. 2004;23(1-2):439-55.

PMID:
15043165
47.

Reduced nonspecific adsorption on covalently immobilized protein surfaces using poly(ethylene oxide) containing blocking agents.

Frederix F, Bonroy K, Reekmans G, Laureyn W, Campitelli A, Abramov MA, Dehaen W, Maes G.

J Biochem Biophys Methods. 2004 Jan 30;58(1):67-74.

PMID:
14597190
48.

[Minimally-invasive combined radiosurgical interventions in diagnosis and treatment of pulmonary artery thromboembolism].

Khrupkin VI, Khanevich MD, Shshelokov AL, Zubritskiĭ VF, Abramov MI, Iaroslavtsev DIu, Karpova RV.

Voen Med Zh. 2003 Jan;324(1):40-5, 96. Russian.

PMID:
12650108
49.

[Treatment of inflammatory conditions of the iris and ciliary body, accompanying fibrin exudation].

Novoderezhkin VV, Egorov EA, Nesterov AP, Egorov AE, Abramov MV, Kasimov EM.

Vestn Oftalmol. 2002 Nov-Dec;118(6):28-9. Russian.

PMID:
12506653
50.

New accelerated strategy for the synthesis of poly(ether ketone) dendrons.

Abramov MA, Shukla R, Amabilino DB, Dehaen W.

J Org Chem. 2002 Feb 8;67(3):1004-7.

PMID:
11856052

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