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Items: 1 to 50 of 151

1.

Optimized Mucosal MVA Prime/Soluble gp120 Boost Vaccination Regimen Induces Similar Antibody Responses as an Intramuscular Regimen.

Jones DI, Pollara JJ, Johnson-Weaver BT, LaBranche CC, Montefiori DC, Pickup DJ, Permar SR, Abraham SN, Maddaloni M, Pascual DW, Staats HF.

J Virol. 2019 May 8. pii: JVI.00475-19. doi: 10.1128/JVI.00475-19. [Epub ahead of print]

PMID:
31068425
2.

Identification of Novel Mast Cell Activators Using Cell-Based High-Throughput Screening.

Choi HW, Chan C, Shterev ID, Lynch HE, Robinette TJ, Johnson-Weaver BT, Shi J, Sempowski GD, Kim SY, Dickson JK, Gooden DM, Abraham SN, Staats HF.

SLAS Discov. 2019 Jul;24(6):628-640. doi: 10.1177/2472555219834699. Epub 2019 Mar 27.

PMID:
30917061
3.

MRGPR-mediated activation of local mast cells clears cutaneous bacterial infection and protects against reinfection.

Arifuzzaman M, Mobley YR, Choi HW, Bist P, Salinas CA, Brown ZD, Chen SL, Staats HF, Abraham SN.

Sci Adv. 2019 Jan 2;5(1):eaav0216. doi: 10.1126/sciadv.aav0216. eCollection 2019 Jan.

4.

Perivascular dendritic cells elicit anaphylaxis by relaying allergens to mast cells via microvesicles.

Choi HW, Suwanpradid J, Kim IH, Staats HF, Haniffa M, MacLeod AS, Abraham SN.

Science. 2018 Nov 9;362(6415). pii: eaao0666. doi: 10.1126/science.aao0666.

5.

Particulate allergens potentiate allergic asthma in mice through sustained IgE-mediated mast cell activation.

Jin C, Shelburne CP, Li G, Potts EN, Riebe KJ, Sempowski GD, Foster WM, Abraham SN.

J Clin Invest. 2018 Oct 1;128(10):4742-4743. doi: 10.1172/JCI123039. Epub 2018 Oct 1. No abstract available.

6.

Necroptosis of infiltrated macrophages drives Yersinia pestis dispersal within buboes.

Arifuzzaman M, Ang WXG, Choi HW, Nilles ML, St John AL, Abraham SN.

JCI Insight. 2018 Sep 20;3(18). pii: 122188. doi: 10.1172/jci.insight.122188. eCollection 2018 Sep 20.

7.

Flavivirus serocomplex cross-reactive immunity is protective by activating heterologous memory CD4 T cells.

Saron WAA, Rathore APS, Ting L, Ooi EE, Low J, Abraham SN, St John AL.

Sci Adv. 2018 Jul 4;4(7):eaar4297. doi: 10.1126/sciadv.aar4297. eCollection 2018 Jul.

8.

In Vitro and In Vivo IgE-/Antigen-Mediated Mast Cell Activation.

Choi HW, Abraham SN.

Methods Mol Biol. 2018;1799:71-80. doi: 10.1007/978-1-4939-7896-0_7.

PMID:
29956145
9.

Mast cell activators as novel immune regulators.

Johnson-Weaver B, Choi HW, Abraham SN, Staats HF.

Curr Opin Pharmacol. 2018 Aug;41:89-95. doi: 10.1016/j.coph.2018.05.004. Epub 2018 May 26. Review.

PMID:
29843056
10.

Reprograming immunity to food allergens.

St John AL, Ang WXG, Rathore APS, Abraham SN.

J Allergy Clin Immunol. 2018 May;141(5):1936-1939.e2. doi: 10.1016/j.jaci.2018.01.020. Epub 2018 Feb 5. No abstract available.

11.

Particulate allergens potentiate allergic asthma in mice through sustained IgE-mediated mast cell activation.

Jin C, Shelburne CP, Li G, Potts EN, Riebe KJ, Sempowski GD, Foster WM, Abraham SN.

J Clin Invest. 2017 Oct 2;127(10):3913. doi: 10.1172/JCI97321. Epub 2017 Sep 18. No abstract available.

12.

Collaboration between Distinct Rab Small GTPase Trafficking Circuits Mediates Bacterial Clearance from the Bladder Epithelium.

Miao Y, Bist P, Wu J, Zhao Q, Li QJ, Wan Y, Abraham SN.

Cell Host Microbe. 2017 Sep 13;22(3):330-342.e4. doi: 10.1016/j.chom.2017.08.002.

13.

The multiple antibacterial activities of the bladder epithelium.

Wu J, Miao Y, Abraham SN.

Ann Transl Med. 2017 Jan;5(2):35. doi: 10.21037/atm.2016.12.71. Review.

14.

IL-27 Facilitates Skin Wound Healing through Induction of Epidermal Proliferation and Host Defense.

Yang B, Suwanpradid J, Sanchez-Lagunes R, Choi HW, Hoang P, Wang D, Abraham SN, MacLeod AS.

J Invest Dermatol. 2017 May;137(5):1166-1175. doi: 10.1016/j.jid.2017.01.010. Epub 2017 Jan 26.

15.

Innate Immune Responses to Bladder Infection.

Hayes BW, Abraham SN.

Microbiol Spectr. 2016 Dec;4(6). doi: 10.1128/microbiolspec.UTI-0024-2016. Review.

16.

Loss of Bladder Epithelium Induced by Cytolytic Mast Cell Granules.

Choi HW, Bowen SE, Miao Y, Chan CY, Miao EA, Abrink M, Moeser AJ, Abraham SN.

Immunity. 2016 Dec 20;45(6):1258-1269. doi: 10.1016/j.immuni.2016.11.003. Epub 2016 Dec 6.

17.

Mast cell desensitization inhibits calcium flux and aberrantly remodels actin.

Ang WX, Church AM, Kulis M, Choi HW, Burks AW, Abraham SN.

J Clin Invest. 2016 Nov 1;126(11):4103-4118. doi: 10.1172/JCI87492. Epub 2016 Sep 26.

18.

How mast cells make decisions.

Karhausen J, Abraham SN.

J Clin Invest. 2016 Oct 3;126(10):3735-3738. doi: 10.1172/JCI90361. Epub 2016 Sep 19.

19.

Cross-reactive antibodies enhance live attenuated virus infection for increased immunogenicity.

Chan KR, Wang X, Saron WAA, Gan ES, Tan HC, Mok DZL, Zhang SL, Lee YH, Liang C, Wijaya L, Ghosh S, Cheung YB, Tannenbaum SR, Abraham SN, St John AL, Low JGH, Ooi EE.

Nat Microbiol. 2016 Sep 19;1:16164. doi: 10.1038/nmicrobiol.2016.164.

PMID:
27642668
20.

Ubiquitination of Innate Immune Regulator TRAF3 Orchestrates Expulsion of Intracellular Bacteria by Exocyst Complex.

Miao Y, Wu J, Abraham SN.

Immunity. 2016 Jul 19;45(1):94-105. doi: 10.1016/j.immuni.2016.06.023.

21.

Why Serological Responses during Cystitis are Limited.

Choi HW, Abraham SN.

Pathogens. 2016 Feb 14;5(1). pii: E19. doi: 10.3390/pathogens5010019. Review.

22.

Correction notice for TNF-R on mast cells regulate airway responses to Mycoplasma pneumoniae.

Hsia BJ, Ledford JG, Potts-Kant EN, Nikam VS, Lugogo NL, Foster WM, Kraft M, Abraham SN, Wright JR.

J Allergy Clin Immunol. 2016 Jan;137(1):336. doi: 10.1016/j.jaci.2015.09.049. Epub 2015 Nov 21. No abstract available.

23.

The nature of immune responses to urinary tract infections.

Abraham SN, Miao Y.

Nat Rev Immunol. 2015 Oct;15(10):655-63. doi: 10.1038/nri3887. Epub 2015 Sep 21. Review.

24.

A TRP Channel Senses Lysosome Neutralization by Pathogens to Trigger Their Expulsion.

Miao Y, Li G, Zhang X, Xu H, Abraham SN.

Cell. 2015 Jun 4;161(6):1306-19. doi: 10.1016/j.cell.2015.05.009. Epub 2015 May 28.

25.

Complete Genome Sequence of Uropathogenic Escherichia coli Strain CI5.

Mehershahi KS, Abraham SN, Chen SL.

Genome Announc. 2015 May 28;3(3). pii: e00558-15. doi: 10.1128/genomeA.00558-15.

26.

S1P-Dependent trafficking of intracellular yersinia pestis through lymph nodes establishes Buboes and systemic infection.

St John AL, Ang WXG, Huang MN, Kunder CA, Chan EW, Gunn MD, Abraham SN.

Immunity. 2014 Sep 18;41(3):440-450. doi: 10.1016/j.immuni.2014.07.013.

27.

Kidney α-intercalated cells and lipocalin 2: defending the urinary tract.

Miao Y, Abraham SN.

J Clin Invest. 2014 Jul;124(7):2844-6. doi: 10.1172/JCI76630. Epub 2014 Jun 17.

28.

Cromolyn ameliorates acute and chronic injury in a rat lung transplant model.

Chang JC, Leung J, Tang T, Holzknecht ZE, Hartwig MG, Duane Davis R, Parker W, Abraham SN, Lin SS.

J Heart Lung Transplant. 2014 Jul;33(7):749-57. doi: 10.1016/j.healun.2014.03.004. Epub 2014 Mar 27.

29.

Peeing pentraxins.

Miao Y, Abraham SN.

Immunity. 2014 Apr 17;40(4):460-2. doi: 10.1016/j.immuni.2014.03.006.

30.

Mast cell mediator responses and their suppression by pathogenic and commensal microorganisms.

Choi HW, Abraham SN.

Mol Immunol. 2015 Jan;63(1):74-9. doi: 10.1016/j.molimm.2014.02.006. Epub 2014 Mar 11. Review.

31.

Salmonella typhimurium impedes innate immunity with a mast-cell-suppressing protein tyrosine phosphatase, SptP.

Choi HW, Brooking-Dixon R, Neupane S, Lee CJ, Miao EA, Staats HF, Abraham SN.

Immunity. 2013 Dec 12;39(6):1108-20. doi: 10.1016/j.immuni.2013.11.009.

32.

A Mast Cell Degranulation Screening Assay for the Identification of Novel Mast Cell Activating Agents.

Staats HF, Kirwan SM, Choi HW, Shelburne CP, Abraham SN, Leung GY, Chen DY.

Medchemcomm. 2013 Jan 1;4(1). doi: 10.1039/C2MD20073B.

33.

Barriers to preclinical investigations of anti-dengue immunity and dengue pathogenesis.

St John AL, Abraham SN, Gubler DJ.

Nat Rev Microbiol. 2013 Jun;11(6):420-6. doi: 10.1038/nrmicro3030. Epub 2013 May 8. Review.

PMID:
23652323
34.

Contributions of mast cells and vasoactive products, leukotrienes and chymase, to dengue virus-induced vascular leakage.

St John AL, Rathore AP, Raghavan B, Ng ML, Abraham SN.

Elife. 2013 Apr 30;2:e00481. doi: 10.7554/eLife.00481.

35.

Innate immunity and its regulation by mast cells.

St John AL, Abraham SN.

J Immunol. 2013 May 1;190(9):4458-63. doi: 10.4049/jimmunol.1203420. Review.

36.

Interplay between vesicoureteric reflux and kidney infection in the development of reflux nephropathy in mice.

Bowen SE, Watt CL, Murawski IJ, Gupta IR, Abraham SN.

Dis Model Mech. 2013 Jul;6(4):934-41. doi: 10.1242/dmm.011650. Epub 2013 Mar 15.

37.

Intestinal mast cells mediate gut injury and systemic inflammation in a rat model of deep hypothermic circulatory arrest.

Karhausen J, Qing M, Gibson A, Moeser AJ, Griefingholt H, Hale LP, Abraham SN, Mackensen GB.

Crit Care Med. 2013 Sep;41(9):e200-10. doi: 10.1097/CCM.0b013e31827cac7a.

38.

Mast cell interleukin-10 drives localized tolerance in chronic bladder infection.

Chan CY, St John AL, Abraham SN.

Immunity. 2013 Feb 21;38(2):349-59. doi: 10.1016/j.immuni.2012.10.019. Epub 2013 Feb 15.

39.

A comparison of non-toxin vaccine adjuvants for their ability to enhance the immunogenicity of nasally-administered anthrax recombinant protective antigen.

Gwinn WM, Johnson BT, Kirwan SM, Sobel AE, Abraham SN, Gunn MD, Staats HF.

Vaccine. 2013 Mar 1;31(11):1480-9. doi: 10.1016/j.vaccine.2013.01.012. Epub 2013 Jan 23.

40.

Convergent Evolution of Calcineurin Pathway Roles in Thermotolerance and Virulence in Candida glabrata.

Chen YL, Konieczka JH, Springer DJ, Bowen SE, Zhang J, Silao FG, Bungay AA, Bigol UG, Nicolas MG, Abraham SN, Thompson DA, Regev A, Heitman J.

G3 (Bethesda). 2012 Jun;2(6):675-91. doi: 10.1534/g3.112.002279. Epub 2012 Jun 1.

41.

Mast cell TNF receptors regulate responses to Mycoplasma pneumoniae in surfactant protein A (SP-A)-/- mice.

Hsia BJ, Ledford JG, Potts-Kant EN, Nikam VS, Lugogo NL, Foster WM, Kraft M, Abraham SN, Wright JR.

J Allergy Clin Immunol. 2012 Jul;130(1):205-14.e2. doi: 10.1016/j.jaci.2012.03.002. Epub 2012 Apr 12.

42.

Increased Nitric Oxide Production Prevents Airway Hyperresponsiveness in Caveolin-1 Deficient Mice Following Endotoxin Exposure.

Hsia BJ, Pastva AM, Giamberardino CD, Potts-Kant EN, Foster WM, Que LG, Abraham SN, Wright JR, Zaas DW.

J Allergy Ther. 2012 Jan 25;Suppl 1(4). pii: 2155-.

43.

Synthetic mast-cell granules as adjuvants to promote and polarize immunity in lymph nodes.

St John AL, Chan CY, Staats HF, Leong KW, Abraham SN.

Nat Mater. 2012 Jan 22;11(3):250-7. doi: 10.1038/nmat3222.

44.

Plasticity in mast cell responses during bacterial infections.

Chan CY, St John AL, Abraham SN.

Curr Opin Microbiol. 2012 Feb;15(1):78-84. doi: 10.1016/j.mib.2011.10.007. Epub 2011 Nov 4. Review.

45.

Mast cell modulation of the vascular and lymphatic endothelium.

Kunder CA, St John AL, Abraham SN.

Blood. 2011 Nov 17;118(20):5383-93. doi: 10.1182/blood-2011-07-358432. Epub 2011 Sep 8. Review.

46.

Stable dry powder formulation for nasal delivery of anthrax vaccine.

Wang SH, Kirwan SM, Abraham SN, Staats HF, Hickey AJ.

J Pharm Sci. 2012 Jan;101(1):31-47. doi: 10.1002/jps.22742. Epub 2011 Sep 8.

47.

The mast cell in innate and adaptive immunity.

Shelburne CP, Abraham SN.

Adv Exp Med Biol. 2011;716:162-85. doi: 10.1007/978-1-4419-9533-9_10. Review.

PMID:
21713657
48.

Immune surveillance by mast cells during dengue infection promotes natural killer (NK) and NKT-cell recruitment and viral clearance.

St John AL, Rathore AP, Yap H, Ng ML, Metcalfe DD, Vasudevan SG, Abraham SN.

Proc Natl Acad Sci U S A. 2011 May 31;108(22):9190-5. doi: 10.1073/pnas.1105079108. Epub 2011 May 16.

49.

c-Kit is essential for alveolar maintenance and protection from emphysema-like disease in mice.

Lindsey JY, Ganguly K, Brass DM, Li Z, Potts EN, Degan S, Chen H, Brockway B, Abraham SN, Berndt A, Stripp BR, Foster WM, Leikauf GD, Schulz H, Hollingsworth JW.

Am J Respir Crit Care Med. 2011 Jun 15;183(12):1644-52. doi: 10.1164/rccm.201007-1157OC. Epub 2011 Mar 11.

50.

Mucosal targeting of a BoNT/A subunit vaccine adjuvanted with a mast cell activator enhances induction of BoNT/A neutralizing antibodies in rabbits.

Staats HF, Fielhauer JR, Thompson AL, Tripp AA, Sobel AE, Maddaloni M, Abraham SN, Pascual DW.

PLoS One. 2011 Jan 27;6(1):e16532. doi: 10.1371/journal.pone.0016532.

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