Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 346

1.

Cardioprotective Heme Oxygenase-1-PGC1α Signaling in Epicardial Fat Attenuates Cardiovascular Risk in Humans as in Obese Mice.

Singh SP, McClung JA, Thompson E, Glick Y, Greenberg M, Acosta-Baez G, Edris B, Shapiro JI, Abraham NG.

Obesity (Silver Spring). 2019 Oct;27(10):1634-1643. doi: 10.1002/oby.22608. Epub 2019 Aug 23.

2.

HO-1 overexpression and underexpression: Clinical implications.

Drummond GS, Baum J, Greenberg M, Lewis D, Abraham NG.

Arch Biochem Biophys. 2019 Sep 30;673:108073. doi: 10.1016/j.abb.2019.108073. Epub 2019 Aug 16. Review.

3.

Beneficial Role of HO-1-SIRT1 Axis in Attenuating Angiotensin II-Induced Adipocyte Dysfunction.

Lakhani HV, Zehra M, Pillai SS, Puri N, Shapiro JI, Abraham NG, Sodhi K.

Int J Mol Sci. 2019 Jun 29;20(13). pii: E3205. doi: 10.3390/ijms20133205.

4.

Targeting Heme Oxygenase-1 in Cardiovascular and Kidney Disease.

Drummond HA, Mitchell ZL, Abraham NG, Stec DE.

Antioxidants (Basel). 2019 Jun 18;8(6). pii: E181. doi: 10.3390/antiox8060181. Review.

5.

The Adipocyte Na/K-ATPase Oxidant Amplification Loop is the Central Regulator of Western Diet-Induced Obesity and Associated Comorbidities.

Pratt RD, Brickman C, Nawab A, Cottrill C, Snoad B, Lakhani HV, Jelcick A, Henderson B, Bhardwaj NN, Sanabria JR, Liu J, Xie Z, Abraham NG, Shapiro JI, Sodhi K.

Sci Rep. 2019 May 28;9(1):7927. doi: 10.1038/s41598-019-44350-9.

6.

Positive Effects of Heme Oxygenase Upregulation on Adiposity and Vascular Dysfunction: Gene Targeting vs. Pharmacologic Therapy.

Peterson SJ, Rubinstein R, Faroqui M, Raza A, Boumaza I, Zhang Y, Stec D, Abraham NG.

Int J Mol Sci. 2019 May 22;20(10). pii: E2514. doi: 10.3390/ijms20102514.

7.

Epoxyeicosatrienoic intervention improves NAFLD in leptin receptor deficient mice by an increase in PGC1α-HO-1-PGC1α-mitochondrial signaling.

Raffaele M, Bellner L, Singh SP, Favero G, Rezzani R, Rodella LF, Falck JR, Abraham NG, Vanella L.

Exp Cell Res. 2019 Jul 15;380(2):180-187. doi: 10.1016/j.yexcr.2019.04.029. Epub 2019 Apr 27.

PMID:
31039348
8.

Oxidized HDL, Adipokines, and Endothelial Dysfunction: A Potential Biomarker Profile for Cardiovascular Risk in Women with Obesity.

Peterson SJ, Shapiro JI, Thompson E, Singh S, Liu L, Weingarten JA, O'Hanlon K, Bialczak A, Bhesania SR, Abraham NG.

Obesity (Silver Spring). 2019 Jan;27(1):87-93. doi: 10.1002/oby.22354.

PMID:
30569635
9.

PARP-1 inhibition protects the diabetic heart through activation of SIRT1-PGC-1α axis.

Waldman M, Nudelman V, Shainberg A, Abraham NG, Kornwoski R, Aravot D, Arad M, Hochhauser E.

Exp Cell Res. 2018 Dec 15;373(1-2):112-118. doi: 10.1016/j.yexcr.2018.10.003. Epub 2018 Oct 23.

PMID:
30359575
10.

Correction to: Regulation of diabetic cardiomyopathy by caloric restriction is mediated by intracellular signaling pathways involving 'SIRT1 and PGC-1α'.

Waldman M, Cohen K, Yadin D, Nudelman V, Gorfil D, Laniado-Schwartzman M, Kornwoski R, Aravot D, Abraham NG, Arad M, Hochhauser E.

Cardiovasc Diabetol. 2018 Aug 17;17(1):115. doi: 10.1186/s12933-018-0757-1.

11.

High-fat diet-induced obesity and insulin resistance in CYP4a14-/- mice is mediated by 20-HETE.

Gilani A, Pandey V, Garcia V, Agostinucci K, Singh SP, Schragenheim J, Bellner L, Falck JR, Paudyal MP, Capdevila JH, Abraham NG, Laniado Schwartzman M.

Am J Physiol Regul Integr Comp Physiol. 2018 Nov 1;315(5):R934-R944. doi: 10.1152/ajpregu.00125.2018. Epub 2018 Aug 8.

12.

Regulation of diabetic cardiomyopathy by caloric restriction is mediated by intracellular signaling pathways involving 'SIRT1 and PGC-1α'.

Waldman M, Cohen K, Yadin D, Nudelman V, Gorfil D, Laniado-Schwartzman M, Kornwoski R, Aravot D, Abraham NG, Arad M, Hochhauser E.

Cardiovasc Diabetol. 2018 Aug 2;17(1):111. doi: 10.1186/s12933-018-0754-4. Erratum in: Cardiovasc Diabetol. 2018 Aug 17;17(1):115.

13.

Development of NASH in Obese Mice is Confounded by Adipose Tissue Increase in Inflammatory NOV and Oxidative Stress.

Sacerdoti D, Singh SP, Schragenheim J, Bellner L, Vanella L, Raffaele M, Meissner A, Grant I, Favero G, Rezzani R, Rodella LF, Bamshad D, Lebovics E, Abraham NG.

Int J Hepatol. 2018 Jul 2;2018:3484107. doi: 10.1155/2018/3484107. eCollection 2018.

14.

Ablation of soluble epoxide hydrolase reprogram white fat to beige-like fat through an increase in mitochondrial integrity, HO-1-adiponectin in vitro and in vivo.

Liu L, Puri N, Raffaele M, Schragenheim J, Singh SP, Bradbury JA, Bellner L, Vanella L, Zeldin DC, Cao J, Abraham NG.

Prostaglandins Other Lipid Mediat. 2018 Sep;138:1-8. doi: 10.1016/j.prostaglandins.2018.07.004. Epub 2018 Jul 21.

15.

Kavain Reduces Porphyromonas gingivalis-Induced Adipocyte Inflammation: Role of PGC-1α Signaling.

Singh SP, Huck O, Abraham NG, Amar S.

J Immunol. 2018 Sep 1;201(5):1491-1499. doi: 10.4049/jimmunol.1800321. Epub 2018 Jul 23.

16.

The Na/K-ATPase Oxidant Amplification Loop Regulates Aging.

Sodhi K, Nichols A, Mallick A, Klug RL, Liu J, Wang X, Srikanthan K, Goguet-Rubio P, Nawab A, Pratt R, Lilly MN, Sanabria JR, Xie Z, Abraham NG, Shapiro JI.

Sci Rep. 2018 Jun 26;8(1):9721. doi: 10.1038/s41598-018-26768-9.

17.

EET enhances renal function in obese mice resulting in restoration of HO-1-Mfn1/2 signaling, and decrease in hypertension through inhibition of sodium chloride co-transporter.

Schragenheim J, Bellner L, Cao J, Singh SP, Bamshad D, McClung JA, Maayan O, Meissner A, Grant I, Stier CT Jr, Abraham NG.

Prostaglandins Other Lipid Mediat. 2018 Jul;137:30-39. doi: 10.1016/j.prostaglandins.2018.05.008. Epub 2018 May 19.

18.

CYP-450 Epoxygenase Derived Epoxyeicosatrienoic Acid Contribute To Reversal of Heart Failure in Obesity-Induced Diabetic Cardiomyopathy via PGC-1 α Activation.

Singh SP, McClung JA, Bellner L, Cao J, Waldman M, Schragenheim J, Arad M, Hochhauser E, Falck JR, Weingarten JA, Peterson SJ, Abraham NG.

Cardiovasc Pharm Open Access. 2018;7(1). pii: 233. doi: 10.4172/2329-6607.1000233. Epub 2018 Feb 8.

19.

Corrigendum: Attenuation of Na/K-ATPase Mediated Oxidant Amplification with pNaKtide Ameliorates Experimental Uremic Cardiomyopathy.

Liu J, Tian J, Chaudhry M, Maxwell K, Yan Y, Wang X, Shah PT, Khawaja AA, Martin R, Robinette TJ, El-Hamdani A, Dodrill MW, Sodhi K, Drummond CA, Haller ST, Kennedy DJ, Abraham NG, Xie Z, Shapiro JI.

Sci Rep. 2017 Oct 20;7:46893. doi: 10.1038/srep46893.

20.

The association of NOV/CCN3 with obstructive sleep apnea (OSA): preliminary evidence of a novel biomarker in OSA.

Weingarten JA, Bellner L, Peterson SJ, Zaw M, Chadha P, Singh SP, Abraham NG.

Horm Mol Biol Clin Investig. 2017 Sep 1;31(2). pii: /j/hmbci.2017.31.issue-2/hmbci-2017-0029/hmbci-2017-0029.xml. doi: 10.1515/hmbci-2017-0029.

PMID:
28862983
21.

Ablation of adipose-HO-1 expression increases white fat over beige fat through inhibition of mitochondrial fusion and of PGC1α in female mice.

Singh SP, Grant I, Meissner A, Kappas A, Abraham NG.

Horm Mol Biol Clin Investig. 2017 Aug 1;31(1). pii: /j/hmbci.2017.31.issue-1/hmbci-2017-0027/hmbci-2017-0027.xml. doi: 10.1515/hmbci-2017-0027.

PMID:
28763300
22.

Existence of a Strong Correlation of Biomarkers and miRNA in Females with Metabolic Syndrome and Obesity in a Population of West Virginia.

Goguet-Rubio P, Klug RL, Sharma DL, Srikanthan K, Puri N, Lakhani VH, Nichols A, O'Hanlon KM, Abraham NG, Shapiro JI, Sodhi K.

Int J Med Sci. 2017 Apr 19;14(6):543-553. doi: 10.7150/ijms.18988. eCollection 2017.

23.

EET intervention on Wnt1, NOV, and HO-1 signaling prevents obesity-induced cardiomyopathy in obese mice.

Cao J, Singh SP, McClung JA, Joseph G, Vanella L, Barbagallo I, Jiang H, Falck JR, Arad M, Shapiro JI, Abraham NG.

Am J Physiol Heart Circ Physiol. 2017 Aug 1;313(2):H368-H380. doi: 10.1152/ajpheart.00093.2017. Epub 2017 Jun 2.

24.

pNaKtide Attenuates Steatohepatitis and Atherosclerosis by Blocking Na/K-ATPase/ROS Amplification in C57Bl6 and ApoE Knockout Mice Fed a Western Diet.

Sodhi K, Srikanthan K, Goguet-Rubio P, Nichols A, Mallick A, Nawab A, Martin R, Shah PT, Chaudhry M, Sigdel S, El-Hamdani M, Liu J, Xie Z, Abraham NG, Shapiro JI.

Sci Rep. 2017 Mar 15;7(1):193. doi: 10.1038/s41598-017-00306-5.

25.

Downregulation of PGC-1α Prevents the Beneficial Effect of EET-Heme Oxygenase-1 on Mitochondrial Integrity and Associated Metabolic Function in Obese Mice.

Singh SP, Bellner L, Vanella L, Cao J, Falck JR, Kappas A, Abraham NG.

J Nutr Metab. 2016;2016:9039754. doi: 10.1155/2016/9039754. Epub 2016 Dec 20.

26.

Caloric restriction ameliorates cardiomyopathy in animal model of diabetes.

Cohen K, Waldman M, Abraham NG, Laniado-Schwartzman M, Gurfield D, Aravot D, Arad M, Hochhauser E.

Exp Cell Res. 2017 Jan 1;350(1):147-153. doi: 10.1016/j.yexcr.2016.11.016. Epub 2016 Nov 21.

PMID:
27884680
27.

Epoxyeicosatrienoic Acid as Therapy for Diabetic and Ischemic Cardiomyopathy.

Romashko M, Schragenheim J, Abraham NG, McClung JA.

Trends Pharmacol Sci. 2016 Nov;37(11):945-962. doi: 10.1016/j.tips.2016.08.001. Epub 2016 Sep 13. Review.

PMID:
27633970
28.

Attenuation of Na/K-ATPase Mediated Oxidant Amplification with pNaKtide Ameliorates Experimental Uremic Cardiomyopathy.

Liu J, Tian J, Chaudhry M, Maxwell K, Yan Y, Wang X, Shah PT, Khawaja AA, Martin R, Robinette TJ, El-Hamdani A, Dodrill MW, Sodhi K, Drummond CA, Haller ST, Kennedy DJ, Abraham NG, Xie Z, Shapiro JI.

Sci Rep. 2016 Oct 4;6:34592. doi: 10.1038/srep34592. Erratum in: Sci Rep. 2017 Oct 20;7:46893.

29.

CYP450-mediated Fatty Acid and Eicosanoids in Metabolic Syndrome and Vascular Diseases.

Abraham NG.

Prostaglandins Other Lipid Mediat. 2016 Sep;125:1. doi: 10.1016/j.prostaglandins.2016.08.002. Epub 2016 Aug 31. No abstract available.

PMID:
27591969
30.

PGC-1 alpha regulates HO-1 expression, mitochondrial dynamics and biogenesis: Role of epoxyeicosatrienoic acid.

Singh SP, Schragenheim J, Cao J, Falck JR, Abraham NG, Bellner L.

Prostaglandins Other Lipid Mediat. 2016 Sep;125:8-18. doi: 10.1016/j.prostaglandins.2016.07.004. Epub 2016 Jul 11.

31.

Epoxyeicosatrienoic Acids Regulate Adipocyte Differentiation of Mouse 3T3 Cells, Via PGC-1α Activation, Which Is Required for HO-1 Expression and Increased Mitochondrial Function.

Waldman M, Bellner L, Vanella L, Schragenheim J, Sodhi K, Singh SP, Lin D, Lakhkar A, Li J, Hochhauser E, Arad M, Darzynkiewicz Z, Kappas A, Abraham NG.

Stem Cells Dev. 2016 Jul 15;25(14):1084-94. doi: 10.1089/scd.2016.0072. Epub 2016 Jun 27.

32.

Oxidized HDL is a potent inducer of adipogenesis and causes activation of the Ang-II and 20-HETE systems in human obese females.

Peterson SJ, Vanella L, Gotlinger K, Jiang H, Singh SP, Sodhi K, Maher E, O'Hanlon K, Shapiro JI, Abraham NG.

Prostaglandins Other Lipid Mediat. 2016 Mar;123:68-77. doi: 10.1016/j.prostaglandins.2016.04.004. Epub 2016 May 11. Review.

PMID:
27179555
33.

Oxidized HDL and Isoprostane Exert a Potent Adipogenic Effect on Stem Cells: Where in the Lineage?

Peterson SJ, Vanella L, Bialczak A, Schragenheim J, Li M, Bellner L, Shapiro JI, Abraham NG.

Cell Stem Cells Regen Med. 2016;2(1). doi: 10.16966/2472-6990.109. Epub 2016 Apr 27. No abstract available.

34.

Uric Acid-Induced Adipocyte Dysfunction Is Attenuated by HO-1 Upregulation: Potential Role of Antioxidant Therapy to Target Obesity.

Sodhi K, Hilgefort J, Banks G, Gilliam C, Stevens S, Ansinelli HA, Getty M, Abraham NG, Shapiro JI, Khitan Z.

Stem Cells Int. 2016;2016:8197325. doi: 10.1155/2016/8197325. Epub 2015 Nov 22.

35.

pNaKtide inhibits Na/K-ATPase reactive oxygen species amplification and attenuates adipogenesis.

Sodhi K, Maxwell K, Yan Y, Liu J, Chaudhry MA, Getty M, Xie Z, Abraham NG, Shapiro JI.

Sci Adv. 2015 Oct 16;1(9):e1500781. doi: 10.1126/sciadv.1500781. eCollection 2015 Oct.

36.

Translational Significance of Heme Oxygenase in Obesity and Metabolic Syndrome.

Abraham NG, Junge JM, Drummond GS.

Trends Pharmacol Sci. 2016 Jan;37(1):17-36. doi: 10.1016/j.tips.2015.09.003. Epub 2015 Oct 26. Review.

37.

Characterization of a murine model of cardiorenal syndrome type 1 by high-resolution Doppler sonography.

Pesce P, Cecchetto L, Brocco S, Bolognesi M, Sodhi K, Abraham NG, Sacerdoti D.

J Ultrasound. 2014 Sep 20;18(3):229-35. doi: 10.1007/s40477-014-0129-y. eCollection 2015 Sep.

38.

Fructose Mediated Non-Alcoholic Fatty Liver Is Attenuated by HO-1-SIRT1 Module in Murine Hepatocytes and Mice Fed a High Fructose Diet.

Sodhi K, Puri N, Favero G, Stevens S, Meadows C, Abraham NG, Rezzani R, Ansinelli H, Lebovics E, Shapiro JI.

PLoS One. 2015 Jun 22;10(6):e0128648. doi: 10.1371/journal.pone.0128648. eCollection 2015.

39.

Soluble epoxide hydrolase null mice exhibit female and male differences in regulation of vascular homeostasis.

Vanella L, Canestraro M, Lee CR, Cao J, Zeldin DC, Schwartzman ML, Abraham NG.

Prostaglandins Other Lipid Mediat. 2015 Jul;120:139-47. doi: 10.1016/j.prostaglandins.2015.04.004. Epub 2015 Apr 20.

40.

Normative data for near point of convergence, accommodation, and phoria.

Abraham NG, Srinivasan K, Thomas J.

Oman J Ophthalmol. 2015 Jan-Apr;8(1):14-8. doi: 10.4103/0974-620X.149856.

41.

Agonists of epoxyeicosatrienoic acids reduce infarct size and ameliorate cardiac dysfunction via activation of HO-1 and Wnt1 canonical pathway.

Cao J, Tsenovoy PL, Thompson EA, Falck JR, Touchon R, Sodhi K, Rezzani R, Shapiro JI, Abraham NG.

Prostaglandins Other Lipid Mediat. 2015 Jan-Mar;116-117:76-86. doi: 10.1016/j.prostaglandins.2015.01.002. Epub 2015 Feb 9.

42.

[Long-term effects of heme oxygenase 1 overexpression on post-infarction heart function in diabetic rats].

Li J, Chen TM, Cao J, Chen DY, Wang H, Shi HY, Gao M, Fan Li, Abraham NG.

Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2014 Sep;30(5):421-6. Chinese.

PMID:
25571633
43.

Heme oxygenase-2 deletion impairs macrophage function: implication in wound healing.

Bellner L, Marrazzo G, van Rooijen N, Dunn MW, Abraham NG, Schwartzman ML.

FASEB J. 2015 Jan;29(1):105-15. doi: 10.1096/fj.14-256503. Epub 2014 Oct 23.

44.

HO-1 Upregulation Attenuates Adipocyte Dysfunction, Obesity, and Isoprostane Levels in Mice Fed High Fructose Diets.

Khitan Z, Harsh M, Sodhi K, Shapiro JI, Abraham NG.

J Nutr Metab. 2014;2014:980547. doi: 10.1155/2014/980547. Epub 2014 Sep 9.

45.

CYP2J2 targeting to endothelial cells attenuates adiposity and vascular dysfunction in mice fed a high-fat diet by reprogramming adipocyte phenotype.

Abraham NG, Sodhi K, Silvis AM, Vanella L, Favero G, Rezzani R, Lee C, Zeldin DC, Schwartzman ML.

Hypertension. 2014 Dec;64(6):1352-61. doi: 10.1161/HYPERTENSIONAHA.114.03884. Epub 2014 Sep 22.

46.

Up-regulation of heme oxygenase-1 after infarct initiation reduces mortality, infarct size and left ventricular remodeling: experimental evidence and proof of concept.

Kusmic C, Barsanti C, Matteucci M, Vesentini N, Pelosi G, Abraham NG, L'Abbate A.

J Transl Med. 2014 Apr 5;12:89. doi: 10.1186/1479-5876-12-89.

47.

Heme oxygenase-1 induction improves cardiac function following myocardial ischemia by reducing oxidative stress.

Issan Y, Kornowski R, Aravot D, Shainberg A, Laniado-Schwartzman M, Sodhi K, Abraham NG, Hochhauser E.

PLoS One. 2014 Mar 21;9(3):e92246. doi: 10.1371/journal.pone.0092246. eCollection 2014.

48.

Effects of ellagic Acid on angiogenic factors in prostate cancer cells.

Vanella L, Di Giacomo C, Acquaviva R, Barbagallo I, Li Volti G, Cardile V, Abraham NG, Sorrenti V.

Cancers (Basel). 2013 Jun 19;5(2):726-38. doi: 10.3390/cancers5020726.

49.

Involvement of reactive oxygen species in a feed-forward mechanism of Na/K-ATPase-mediated signaling transduction.

Yan Y, Shapiro AP, Haller S, Katragadda V, Liu L, Tian J, Basrur V, Malhotra D, Xie ZJ, Abraham NG, Shapiro JI, Liu J.

J Biol Chem. 2013 Nov 22;288(47):34249-58. doi: 10.1074/jbc.M113.461020. Epub 2013 Oct 11.

50.

Apoptotic markers in a prostate cancer cell line: effect of ellagic acid.

Vanella L, Di Giacomo C, Acquaviva R, Barbagallo I, Cardile V, Kim DH, Abraham NG, Sorrenti V.

Oncol Rep. 2013 Dec;30(6):2804-10. doi: 10.3892/or.2013.2757. Epub 2013 Sep 30.

PMID:
24085108

Supplemental Content

Loading ...
Support Center