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Items: 46

1.

Proteinuria in children with juvenile idiopathic arthritis: Making the case for early urinary screening.

Saha A, Pais P, Iyengar AA, Abraham AK.

Saudi J Kidney Dis Transpl. 2017 Nov-Dec;28(6):1408-1411. doi: 10.4103/1319-2442.220854.

2.

Erratum to: Optimal Affinity of a Monoclonal Antibody: Guiding Principles Using Mechanistic Modeling.

Tiwari A, Abraham AK, Harrold JM, Zutshi A, Singh P.

AAPS J. 2017 Mar;19(2):597. doi: 10.1208/s12248-017-0046-z. No abstract available.

PMID:
28097628
3.

Optimal Affinity of a Monoclonal Antibody: Guiding Principles Using Mechanistic Modeling.

Tiwari A, Abraham AK, Harrold JM, Zutshi A, Singh P.

AAPS J. 2017 Mar;19(2):510-519. doi: 10.1208/s12248-016-0004-1. Epub 2016 Dec 21. Erratum in: AAPS J. 2017 Mar;19(2):597.

PMID:
28004347
4.

Assessing the Impact of Tissue Target Concentration Data on Uncertainty in In Vivo Target Coverage Predictions.

Tiwari A, Luo H, Chen X, Singh P, Bhattacharya I, Jasper P, Tolsma JE, Jones HM, Zutshi A, Abraham AK.

CPT Pharmacometrics Syst Pharmacol. 2016 Oct;5(10):565-574. doi: 10.1002/psp4.12126. Epub 2016 Oct 22.

5.

Novel Anti-TM4SF1 Antibody-Drug Conjugates with Activity against Tumor Cells and Tumor Vasculature.

Visintin A, Knowlton K, Tyminski E, Lin CI, Zheng X, Marquette K, Jain S, Tchistiakova L, Li D, O'Donnell CJ, Maderna A, Cao X, Dunn R, Snyder WB, Abraham AK, Leal M, Shetty S, Barry A, Zawel L, Coyle AJ, Dvorak HF, Jaminet SC.

Mol Cancer Ther. 2015 Aug;14(8):1868-76. doi: 10.1158/1535-7163.MCT-15-0188. Epub 2015 Jun 18.

6.

Simulations of site-specific target-mediated pharmacokinetic models for guiding the development of bispecific antibodies.

Chudasama VL, Zutshi A, Singh P, Abraham AK, Mager DE, Harrold JM.

J Pharmacokinet Pharmacodyn. 2015 Feb;42(1):1-18. doi: 10.1007/s10928-014-9401-1. Epub 2015 Jan 6.

PMID:
25559227
7.

Ubiquity: a framework for physiological/mechanism-based pharmacokinetic/pharmacodynamic model development and deployment.

Harrold JM, Abraham AK.

J Pharmacokinet Pharmacodyn. 2014 Apr;41(2):141-51. doi: 10.1007/s10928-014-9352-6. Epub 2014 Mar 12.

PMID:
24619141
8.

Optimal in-hospital and discharge medical therapy in acute coronary syndromes in Kerala: results from the Kerala acute coronary syndrome registry.

Huffman MD, Prabhakaran D, Abraham AK, Krishnan MN, Nambiar AC, Mohanan PP; Kerala Acute Coronary Syndrome Registry Investigators.

Circ Cardiovasc Qual Outcomes. 2013 Jul;6(4):436-43. doi: 10.1161/CIRCOUTCOMES.113.000189. Epub 2013 Jun 25.

9.

Pharmacodynamic model of parathyroid hormone modulation by a negative allosteric modulator of the calcium-sensing receptor.

Abraham AK, Maurer TS, Kalgutkar AS, Gao X, Li M, Healy DR, Petersen DN, Griffith DA, Mager DE.

AAPS J. 2011 Jun;13(2):265-73. doi: 10.1208/s12248-011-9266-9. Epub 2011 Mar 25.

10.

Type I interferon receptor is a primary regulator of target-mediated drug disposition of interferon-beta in mice.

Abraham AK, Kagan L, Kumar S, Mager DE.

J Pharmacol Exp Ther. 2010 Jul;334(1):327-32. doi: 10.1124/jpet.110.167650. Epub 2010 Apr 20.

11.

Interspecies scaling of receptor-mediated pharmacokinetics and pharmacodynamics of type I interferons.

Kagan L, Abraham AK, Harrold JM, Mager DE.

Pharm Res. 2010 May;27(5):920-32. doi: 10.1007/s11095-010-0098-6. Epub 2010 Mar 16.

12.

Mechanisms of interferon-beta effects on bone homeostasis.

Abraham AK, Ramanathan M, Weinstock-Guttman B, Mager DE.

Biochem Pharmacol. 2009 Jun 15;77(12):1757-62. doi: 10.1016/j.bcp.2009.01.007. Epub 2009 Jan 22. Review.

PMID:
19428330
13.

Mechanism-based pharmacokinetic/pharmacodynamic model of parathyroid hormone-calcium homeostasis in rats and humans.

Abraham AK, Mager DE, Gao X, Li M, Healy DR, Maurer TS.

J Pharmacol Exp Ther. 2009 Jul;330(1):169-78. doi: 10.1124/jpet.109.152033. Epub 2009 Apr 22.

PMID:
19386792
14.
15.

Effect of spermidine on the activation of homocysteine.

Leirvaag B, Strand I, Abraham AK.

Biochem Soc Trans. 1998 Nov;26(4):S374. No abstract available.

PMID:
10047888
16.

A novel pathway for the conversion of homocysteine to methionine in eukaryotes.

Antonio CM, Nunes MC, Refsum H, Abraham AK.

Biochem J. 1997 Nov 15;328 ( Pt 1):165-70.

17.

Translational fidelity of methionyl-tRNA synthetase.

Abraham AK.

Biochem Soc Trans. 1997 Feb;25(1):52S. No abstract available.

PMID:
9056950
18.

Crimean-Congo haemorrhagic fever in Oman.

Scrimgeour EM, Zaki A, Mehta FR, Abraham AK, Al-Busaidy S, El-Khatim H, Al-Rawas SF, Kamal AM, Mohammed AJ.

Trans R Soc Trop Med Hyg. 1996 May-Jun;90(3):290-1. No abstract available.

PMID:
8758080
19.

Crimean-Congo haemorrhagic fever in Oman.

Schwarz TF, Nitschko H, Jäger G, Nsanze H, Longson M, Pugh RN, Abraham AK.

Lancet. 1995 Nov 4;346(8984):1230. No abstract available.

PMID:
7475685
20.

Kinetics of ribosomal protein S6 phosphorylation by HepG-2 cells in response to insulin.

Abraham AK, Khatim MS.

Biochem Biophys Res Commun. 1989 Jun 15;161(2):797-802.

PMID:
2544175
21.

A precaution when preparing very large plasmids by alkaline lysis procedure.

Thomas NR, Koshy S, Simsek M, Abraham AK.

Biotechnol Appl Biochem. 1988 Oct;10(5):402-7.

PMID:
2848541
22.

Translation of globin RNA spliced in vitro.

Abraham AK, Burns G, Simsek M.

Biochem J. 1988 Aug 15;254(1):21-6.

23.

Total occlusion of the left main coronary artery in chronic stable angina pectoris.

Sudhir K, Abraham AK, Cherian MK, Reddy NK, Gupta S.

Cathet Cardiovasc Diagn. 1987 Sep-Oct;13(5):317-20.

PMID:
3664630
24.

Quadrivalvular rheumatic heart disease.

Gupta SK, Abraham AK, Mani GK, Cherian KM, Moorthy JS, Bhaskaran K.

Jpn Heart J. 1987 Jul;28(4):507-14.

PMID:
3682187
25.

Supernumerary right coronary artery.

Gupta SK, Abraham AK, Reddy NK, Moorthy SJ.

Clin Cardiol. 1987 Jul;10(7):425-7.

26.

Pulmonary atresia with ventricular septal defect in adult patients.

Sudhir K, Gupta SK, Abraham AK, Cherian MP, Reddy NK, Cherian MK.

Clin Cardiol. 1987 May;10(5):350-4.

27.
28.

Nucleotide binding to elongation factor 2 inactivated by diphtheria toxin.

Burns G, Abraham AK, Vedeler A.

FEBS Lett. 1986 Nov 24;208(2):217-20.

29.

Culture negative infective endocarditis.

Abraham AK, Neutze JM, MacCulloch D, Cornere B.

Aust N Z J Med. 1984 Jun;14(3):223-6.

PMID:
6388550
30.

Effect of protein synthesis inhibitors on the fidelity of translation in eukaryotic systems.

Abraham AK, Pihl A.

Biochim Biophys Acta. 1983 Nov 17;741(2):197-203.

PMID:
6652088
31.

The fidelity of translation.

Abraham AK.

Prog Nucleic Acid Res Mol Biol. 1983;28:81-100. Review. No abstract available.

PMID:
6136066
32.

Removal of wheat-germ agglutinin increases protein synthesis in wheat-germ extracts.

Abraham AK, Kolseth S, Pihl A.

Eur J Biochem. 1982 May 17;124(2):383-8.

33.

Sequential AV pacing in right ventricular myocardial infarction with complete heart block.

Abraham AK.

Am Heart J. 1982 May;103(5):929. No abstract available.

PMID:
7072605
34.

Inhibition of mitochondrial protein synthesis and energy coupling by fragment A of diphtheria toxin.

Abraham AK, Flatmark T, Tangerås A, Pihl A.

Eur J Biochem. 1982 Mar;123(1):201-7.

35.

Effect of polyamines on the fidelity of macromolecular synthesis.

Abraham AK.

Med Biol. 1981 Dec;59(5-6):368-73.

PMID:
6175858
36.

Polypeptide synthesis by mitoplasts isolated from mouse liver.

Abraham AK, Vedeler A, Reistad R, Pihl A.

Exp Cell Res. 1981 Apr;132(2):265-72. No abstract available.

PMID:
7215445
37.

Specificity of RNA binding by the structural protein (p10) of Friend murine leukemia virus.

Nissen-Meyer J, Abraham AK.

J Mol Biol. 1980 Sep 5;142(1):19-28. No abstract available.

PMID:
7431407
38.

Turnover of the poly(A) moiety of mRNA in wheat-germ extract.

Abraham AK, Pihl A, Jacob ST.

Eur J Biochem. 1980 Sep;110(1):1-5.

39.

Variable rate of polypeptide chain elongation in vitro. Effect of spermidine.

Abraham AK, Pihl A.

Eur J Biochem. 1980 May;106(1):257-62.

40.

Fidelity of protein synthesis in vitro is increased in the presence of spermidine.

Abraham AK, Olsnes S, Pihl A.

FEBS Lett. 1979 May 1;101(1):93-6. No abstract available.

42.

Hydrolysis of poly (A) to adenine nucleotides by purified poly (A) polymerase.

Abraham AK, Jacob ST.

Proc Natl Acad Sci U S A. 1978 May;75(5):2085-7.

43.

Formation of ATP from the poly-adenylated region of eukaryotic messenger RNAs.

Abraham AK, Pihl A.

FEBS Lett. 1978 Mar 1;87(1):121-4. No abstract available.

44.

Effect of abrin on peptide chain initiation.

Skorve J, Abraham AK, Olsnes S, Pihl A.

Eur J Biochem. 1977 Oct 3;79(2):559-64. No abstract available.

45.
46.

The electrocardiographic profile in tetralogy of Fallot.

Abraham AK, Sukumar IP, Krishnaswami S, McArthur JD, John S, Cherian G.

Indian Heart J. 1974 Apr;26(2):106-9. No abstract available.

PMID:
4419625

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