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Items: 19

1.

Hematopoietic alterations in chronic heart failure patients by somatic mutations leading to clonal hematopoiesis.

Dorsheimer L, Assmus B, Rasper T, Ortmann CA, Abou-El-Ardat K, Kiefer KC, Hoffmann J, Seeger F, Bonig H, Dimmeler S, Zeiher AM, Rieger MA.

Haematologica. 2019 Nov 7. pii: haematol.2019.224402. doi: 10.3324/haematol.2019.224402. [Epub ahead of print]

2.

Deep sequencing of a recurrent oligodendroglioma and the derived xenografts reveals new insights into the evolution of human oligodendroglioma and candidate driver genes.

Exner ND, Valenzuela JAC, Abou-El-Ardat K, Miletic H, Huszthy PC, Radehaus PM, Schröck E, Bjerkvig R, Kaderali L, Klink B, Nigro JM.

Oncotarget. 2019 Jun 4;10(38):3641-3653. doi: 10.18632/oncotarget.26950. eCollection 2019 Jun 4.

3.

Functional Dominance of CHIP-Mutated Hematopoietic Stem Cells in Patients Undergoing Autologous Transplantation.

Ortmann CA, Dorsheimer L, Abou-El-Ardat K, Hoffrichter J, Assmus B, Bonig H, Scholz A, Pfeifer H, Martin H, Schmid T, Brüne B, Scheich S, Steffen B, Riemann J, Hermann S, Dukat A, Bug G, Brandts CH, Wagner S, Serve H, Rieger MA.

Cell Rep. 2019 May 14;27(7):2022-2028.e3. doi: 10.1016/j.celrep.2019.04.064.

4.

Correction: LSD1 inhibition by tranylcypromine derivatives interferes with GFI1-mediated repression of PU.1 target genes and induces differentiation in AML.

Barth J, Abou-El-Ardat K, Dalic D, Kurrle N, Maier AM, Mohr S, Schütte J, Vassen L, Greve G, Schulz-Fincke J, Schmitt M, Tosic M, Metzger E, Bug G, Khandanpour C, Wagner SA, Lübbert M, Jung M, Serve H, Schüle R, Berg T.

Leukemia. 2019 Jun;33(6):1541. doi: 10.1038/s41375-019-0415-y.

PMID:
30837671
5.

LSD1 inhibition by tranylcypromine derivatives interferes with GFI1-mediated repression of PU.1 target genes and induces differentiation in AML.

Barth J, Abou-El-Ardat K, Dalic D, Kurrle N, Maier AM, Mohr S, Schütte J, Vassen L, Greve G, Schulz-Fincke J, Schmitt M, Tosic M, Metzger E, Bug G, Khandanpour C, Wagner SA, Lübbert M, Jung M, Serve H, Schüle R, Berg T.

Leukemia. 2019 Jun;33(6):1411-1426. doi: 10.1038/s41375-018-0375-7. Epub 2019 Jan 24. Erratum in: Leukemia. 2019 Mar 5;:.

PMID:
30679800
6.

Association of Mutations Contributing to Clonal Hematopoiesis With Prognosis in Chronic Ischemic Heart Failure.

Dorsheimer L, Assmus B, Rasper T, Ortmann CA, Ecke A, Abou-El-Ardat K, Schmid T, Brüne B, Wagner S, Serve H, Hoffmann J, Seeger F, Dimmeler S, Zeiher AM, Rieger MA.

JAMA Cardiol. 2019 Jan 1;4(1):25-33. doi: 10.1001/jamacardio.2018.3965.

7.

Loperamide, pimozide, and STF-62247 trigger autophagy-dependent cell death in glioblastoma cells.

Zielke S, Meyer N, Mari M, Abou-El-Ardat K, Reggiori F, van Wijk SJL, Kögel D, Fulda S.

Cell Death Dis. 2018 Sep 24;9(10):994. doi: 10.1038/s41419-018-1003-1.

8.

Comprehensive molecular characterization of multifocal glioblastoma proves its monoclonal origin and reveals novel insights into clonal evolution and heterogeneity of glioblastomas.

Abou-El-Ardat K, Seifert M, Becker K, Eisenreich S, Lehmann M, Hackmann K, Rump A, Meijer G, Carvalho B, Temme A, Schackert G, Schröck E, Krex D, Klink B.

Neuro Oncol. 2017 Apr 1;19(4):546-557. doi: 10.1093/neuonc/now231.

9.

Ultrasound measurement of cervical length as predictor of threatened preterm birth: a predictive model.

El-Ardat MA, Gavrankapetanovic F, Abou El-Ardat KA, Dekovic S, Murtezic S, Mehmedbasic E, Hiros N.

Acta Inform Med. 2014 Oct;22(5):306-8. doi: 10.5455/aim.2014.22.306-308. Epub 2014 Oct 29.

10.

Autoregressive higher-order hidden Markov models: exploiting local chromosomal dependencies in the analysis of tumor expression profiles.

Seifert M, Abou-El-Ardat K, Friedrich B, Klink B, Deutsch A.

PLoS One. 2014 Jun 23;9(6):e100295. doi: 10.1371/journal.pone.0100295. eCollection 2014.

11.

Chronic exposure to simulated space conditions predominantly affects cytoskeleton remodeling and oxidative stress response in mouse fetal fibroblasts.

Beck M, Moreels M, Quintens R, Abou-El-Ardat K, El-Saghire H, Tabury K, Michaux A, Janssen A, Neefs M, Van Oostveldt P, De Vos WH, Baatout S.

Int J Mol Med. 2014 Aug;34(2):606-15. doi: 10.3892/ijmm.2014.1785. Epub 2014 May 22.

PMID:
24859186
12.

Epigallocatechin-3-gallate inhibits tax-dependent activation of nuclear factor kappa B and of matrix metalloproteinase 9 in human T-cell lymphotropic virus-1 positive leukemia cells.

Harakeh S, Diab-Assaf M, Azar R, Hassan HM, Tayeb S, Abou-El-Ardat K, Damanhouri GA, Qadri I, Abuzenadah A, Chaudhary A, Kumosani T, Niedzwiecki A, Rath M, Yacoub H, Azhar E, Barbour E.

Asian Pac J Cancer Prev. 2014;15(3):1219-25.

13.

Novel CIC point mutations and an exon-spanning, homozygous deletion identified in oligodendroglial tumors by a comprehensive genomic approach including transcriptome sequencing.

Eisenreich S, Abou-El-Ardat K, Szafranski K, Campos Valenzuela JA, Rump A, Nigro JM, Bjerkvig R, Gerlach EM, Hackmann K, Schröck E, Krex D, Kaderali L, Schackert G, Platzer M, Klink B.

PLoS One. 2013 Sep 27;8(9):e76623. doi: 10.1371/journal.pone.0076623. eCollection 2013.

14.

Gravity-sensitive signaling drives 3-dimensional formation of multicellular thyroid cancer spheroids.

Grosse J, Wehland M, Pietsch J, Schulz H, Saar K, Hübner N, Eilles C, Bauer J, Abou-El-Ardat K, Baatout S, Ma X, Infanger M, Hemmersbach R, Grimm D.

FASEB J. 2012 Dec;26(12):5124-40. doi: 10.1096/fj.12-215749. Epub 2012 Sep 10.

PMID:
22964303
15.

Iodine-deficiency-induced long lasting angiogenic reaction in thyroid cancers occurs via a vascular endothelial growth factor-hypoxia inducible factor-1-dependent, but not a reactive oxygen species-dependent, pathway.

Gérard AC, Humblet K, Wilvers C, Poncin S, Derradji H, de Ville de Goyet C, Abou-el-Ardat K, Baatout S, Sonveaux P, Denef JF, Colin IM.

Thyroid. 2012 Jul;22(7):699-708. doi: 10.1089/thy.2011.0387. Epub 2012 Jun 4.

PMID:
22663304
16.

Low dose irradiation of thyroid cells reveals a unique transcriptomic and epigenetic signature in RET/PTC-positive cells.

Abou-El-Ardat K, Monsieurs P, Anastasov N, Atkinson M, Derradji H, De Meyer T, Bekaert S, Van Criekinge W, Baatout S.

Mutat Res. 2012 Mar 1;731(1-2):27-40. doi: 10.1016/j.mrfmmm.2011.10.006. Epub 2011 Oct 20.

PMID:
22027090
17.

Response to low-dose X-irradiation is p53-dependent in a papillary thyroid carcinoma model system.

Abou-El-Ardat K, Derradji H, de Vos W, de Meyer T, Bekaert S, van Criekinge W, Baatout S.

Int J Oncol. 2011 Dec;39(6):1429-41. doi: 10.3892/ijo.2011.1175. Epub 2011 Aug 29.

PMID:
21879253
18.

Genrisk-T project: response of the TPC-1 papillary thyroid carcinoma cell line to a range of low to high doses of irradiation.

Abou-El-Ardat K, Derradji H, Bekaert S, De Meyer T, Van Criekinge W, Baatout S.

Commun Agric Appl Biol Sci. 2008;73(1):79-83. No abstract available.

PMID:
18831249
19.

Ionizing radiation-induced gene modulations, cytokine content changes and telomere shortening in mouse fetuses exhibiting forelimb defects.

Derradji H, Bekaert S, De Meyer T, Jacquet P, Abou-El-Ardat K, Ghardi M, Arlette M, Baatout S.

Dev Biol. 2008 Oct 15;322(2):302-13. doi: 10.1016/j.ydbio.2008.07.032. Epub 2008 Aug 7.

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