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Items: 26


Dietary methionine influences therapy in mouse cancer models and alters human metabolism.

Gao X, Sanderson SM, Dai Z, Reid MA, Cooper DE, Lu M, Richie JP Jr, Ciccarella A, Calcagnotto A, Mikhael PG, Mentch SJ, Liu J, Ables G, Kirsch DG, Hsu DS, Nichenametla SN, Locasale JW.

Nature. 2019 Aug;572(7769):397-401. doi: 10.1038/s41586-019-1437-3. Epub 2019 Jul 31.


Identification and Application of Gene Expression Signatures Associated with Lifespan Extension.

Tyshkovskiy A, Bozaykut P, Borodinova AA, Gerashchenko MV, Ables GP, Garratt M, Khaitovich P, Clish CB, Miller RA, Gladyshev VN.

Cell Metab. 2019 Sep 3;30(3):573-593.e8. doi: 10.1016/j.cmet.2019.06.018. Epub 2019 Jul 25.


Bone Marrow Adiposity: Basic and Clinical Implications.

Sebo ZL, Rendina-Ruedy E, Ables GP, Lindskog DM, Rodeheffer MS, Fazeli PK, Horowitz MC.

Endocr Rev. 2019 Oct 1;40(5):1187-1206. doi: 10.1210/er.2018-00138.


Dietary methionine restriction modulates renal response and attenuates kidney injury in mice.

Cooke D, Ouattara A, Ables GP.

FASEB J. 2018 Feb;32(2):693-702. doi: 10.1096/fj.201700419R. Epub 2018 Jan 4.


Bone marrow adipocytes.

Horowitz MC, Berry R, Holtrup B, Sebo Z, Nelson T, Fretz JA, Lindskog D, Kaplan JL, Ables G, Rodeheffer MS, Rosen CJ.

Adipocyte. 2017 Jul 3;6(3):193-204. doi: 10.1080/21623945.2017.1367881. Epub 2017 Aug 24. Review.


Pleiotropic responses to methionine restriction.

Ables GP, Johnson JE.

Exp Gerontol. 2017 Aug;94:83-88. doi: 10.1016/j.exger.2017.01.012. Epub 2017 Jan 17. Review.


Short term methionine restriction increases hepatic global DNA methylation in adult but not young male C57BL/6J mice.

Mattocks DA, Mentch SJ, Shneyder J, Ables GP, Sun D, Richie JP Jr, Locasale JW, Nichenametla SN.

Exp Gerontol. 2017 Feb;88:1-8. doi: 10.1016/j.exger.2016.12.003. Epub 2016 Dec 7.


Methionine restriction beyond life-span extension.

Ables GP, Hens JR, Nichenametla SN.

Ann N Y Acad Sci. 2016 Jan;1363:68-79. doi: 10.1111/nyas.13014. Epub 2016 Feb 24. Review.


Dietary restrictions, bone density, and bone quality.

Huang TH, Ables GP.

Ann N Y Acad Sci. 2016 Jan;1363:26-39. doi: 10.1111/nyas.13004. Epub 2016 Feb 16. Review.


Methionine restriction alters bone morphology and affects osteoblast differentiation.

Ouattara A, Cooke D, Gopalakrishnan R, Huang TH, Ables GP.

Bone Rep. 2016 Feb 11;5:33-42. doi: 10.1016/j.bonr.2016.02.002. eCollection 2016 Dec.


Histone Methylation Dynamics and Gene Regulation Occur through the Sensing of One-Carbon Metabolism.

Mentch SJ, Mehrmohamadi M, Huang L, Liu X, Gupta D, Mattocks D, Gómez Padilla P, Ables G, Bamman MM, Thalacker-Mercer AE, Nichenametla SN, Locasale JW.

Cell Metab. 2015 Nov 3;22(5):861-73. doi: 10.1016/j.cmet.2015.08.024. Epub 2015 Sep 24.


Effects of methionine restriction and endurance exercise on bones of ovariectomized rats: a study of histomorphometry, densitometry, and biomechanical properties.

Huang TH, Su IH, Lewis JL, Chang MS, Hsu AT, Perrone CE, Ables GP.

J Appl Physiol (1985). 2015 Sep 1;119(5):517-26. doi: 10.1152/japplphysiol.00395.2015. Epub 2015 Jul 9.


Dietary methionine restriction in mice elicits an adaptive cardiovascular response to hyperhomocysteinemia.

Ables GP, Ouattara A, Hampton TG, Cooke D, Perodin F, Augie I, Orentreich DS.

Sci Rep. 2015 Mar 6;5:8886. doi: 10.1038/srep08886.


The first international mini-symposium on methionine restriction and lifespan.

Ables GP, Brown-Borg HM, Buffenstein R, Church CD, Elshorbagy AK, Gladyshev VN, Huang TH, Miller RA, Mitchell JR, Richie JP, Rogina B, Stipanuk MH, Orentreich DS, Orentreich N.

Front Genet. 2014 May 9;5:122. doi: 10.3389/fgene.2014.00122. eCollection 2014.


A methionine-restricted diet and endurance exercise decrease bone mass and extrinsic strength but increase intrinsic strength in growing male rats.

Huang TH, Lewis JL, Lin HS, Kuo LT, Mao SW, Tai YS, Chang MS, Ables GP, Perrone CE, Yang RS.

J Nutr. 2014 May;144(5):621-30. doi: 10.3945/jn.113.187922. Epub 2014 Mar 19.


Methionine restriction prevents the progression of hepatic steatosis in leptin-deficient obese mice.

Malloy VL, Perrone CE, Mattocks DA, Ables GP, Caliendo NS, Orentreich DS, Orentreich N.

Metabolism. 2013 Nov;62(11):1651-61. doi: 10.1016/j.metabol.2013.06.012. Epub 2013 Aug 5.


Methionine-restricted C57BL/6J mice are resistant to diet-induced obesity and insulin resistance but have low bone density.

Ables GP, Perrone CE, Orentreich D, Orentreich N.

PLoS One. 2012;7(12):e51357. doi: 10.1371/journal.pone.0051357. Epub 2012 Dec 7. Erratum in: PLoS One. 2014;9(7):e104050.


Update on pparγ and nonalcoholic Fatty liver disease.

Ables GP.

PPAR Res. 2012;2012:912351. doi: 10.1155/2012/912351. Epub 2012 Aug 16.


Intestinal DGAT1 deficiency reduces postprandial triglyceride and retinyl ester excursions by inhibiting chylomicron secretion and delaying gastric emptying.

Ables GP, Yang KJ, Vogel S, Hernandez-Ono A, Yu S, Yuen JJ, Birtles S, Buckett LK, Turnbull AV, Goldberg IJ, Blaner WS, Huang LS, Ginsberg HN.

J Lipid Res. 2012 Nov;53(11):2364-79. doi: 10.1194/jlr.M029041. Epub 2012 Aug 21.


DGAT1 deficiency decreases PPAR expression and does not lead to lipotoxicity in cardiac and skeletal muscle.

Liu L, Yu S, Khan RS, Ables GP, Bharadwaj KG, Hu Y, Huggins LA, Eriksson JW, Buckett LK, Turnbull AV, Ginsberg HN, Blaner WS, Huang LS, Goldberg IJ.

J Lipid Res. 2011 Apr;52(4):732-44. doi: 10.1194/jlr.M011395. Epub 2011 Jan 3.


Hepatic overexpression of hormone-sensitive lipase and adipose triglyceride lipase promotes fatty acid oxidation, stimulates direct release of free fatty acids, and ameliorates steatosis.

Reid BN, Ables GP, Otlivanchik OA, Schoiswohl G, Zechner R, Blaner WS, Goldberg IJ, Schwabe RF, Chua SC Jr, Huang LS.

J Biol Chem. 2008 May 9;283(19):13087-99. doi: 10.1074/jbc.M800533200. Epub 2008 Mar 12.


Genetic polymorphisms and antiviral activity in the bovine MX1 gene.

Nakatsu Y, Yamada K, Ueda J, Onogi A, Ables GP, Nishibori M, Hata H, Takada A, Sawai K, Tanabe Y, Morita M, Daikohara M, Watanabe T.

Anim Genet. 2004 Jun;35(3):182-7.


Sequence analysis of the NRAMP1 genes from different bovine and buffalo breeds.

Ables GP, Nishibori M, Kanemaki M, Watanabe T.

J Vet Med Sci. 2002 Nov;64(11):1081-3.


Analysis of genetic factors associated with nitric oxide production in mice.

Ables GP, Hamashima N, Watanabe T.

Biochem Genet. 2001 Dec;39(11-12):379-94.


Male hybrid sterility of mice with the genomic region of the KitW mutation and the KitS allele from Mus spretus.

el-Shazly S, Seo KW, el-Nahas A, Ables GP, Asano A, Watanabe T.

Biochem Genet. 2001 Apr;39(3-4):127-37.


The roles of Nramp1 and Tnfa genes in nitric oxide production and their effect on the growth of Salmonella typhimurium in macrophages from Nramp1 congenic and tumor necrosis factor-alpha-/- mice.

Ables GP, Takamatsu D, Noma H, El-Shazly S, Jin HK, Taniguchi T, Sekikawa K, Watanabe T.

J Interferon Cytokine Res. 2001 Jan;21(1):53-62.


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