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Items: 1 to 50 of 91

1.

SOX2 Regulates P63 and Stem/Progenitor Cell State in the Corneal Epithelium.

Bhattacharya S, Serror L, Nir E, Dhiraj D, Altshuler A, Khreish M, Tiosano B, Hasson P, Panman L, Luxenburg C, Aberdam D, Shalom-Feuerstein R.

Stem Cells. 2019 Mar;37(3):417-429. doi: 10.1002/stem.2959. Epub 2019 Feb 1.

PMID:
30548157
2.

Modeling of Aniridia-Related Keratopathy by CRISPR/Cas9 Genome Editing of Human Limbal Epithelial Cells and Rescue by Recombinant PAX6 Protein.

Roux LN, Petit I, Domart R, Concordet JP, Qu J, Zhou H, Joliot A, Ferrigno O, Aberdam D.

Stem Cells. 2018 Sep;36(9):1421-1429. doi: 10.1002/stem.2858. Epub 2018 Jul 18.

PMID:
29808941
3.

microRNA-184 Induces a Commitment Switch to Epidermal Differentiation.

Nagosa S, Leesch F, Putin D, Bhattacharya S, Altshuler A, Serror L, Amitai-Lange A, Nasser W, Aberdam E, Rouleau M, Tattikota SG, Poy MN, Aberdam D, Shalom-Feuerstein R.

Stem Cell Reports. 2017 Dec 12;9(6):1991-2004. doi: 10.1016/j.stemcr.2017.10.030. Epub 2017 Nov 30.

4.

Induced pluripotent stem cell-derived limbal epithelial cells (LiPSC) as a cellular alternative for in vitro ocular toxicity testing.

Aberdam E, Petit I, Sangari L, Aberdam D.

PLoS One. 2017 Jun 22;12(6):e0179913. doi: 10.1371/journal.pone.0179913. eCollection 2017.

5.

Pluripotent Stem Cells and Other Innovative Strategies for the Treatment of Ocular Surface Diseases.

Erbani J, Aberdam D, Larghero J, Vanneaux V.

Stem Cell Rev. 2016 Apr;12(2):171-8. doi: 10.1007/s12015-016-9643-y. Review.

PMID:
26779895
6.

Pluripotent stem cells as a cellular model for skin: relevance for physiopathology, cell/gene therapy and drug screening.

Levy A, Petit I, Aberdam D.

Eur J Dermatol. 2015 Apr;25 Suppl 1:12-7. Review.

PMID:
26287031
7.

[Metabolic switch in pluripotent stem cells: identification of a novel pathway].

Aberdam D.

Med Sci (Paris). 2015 Jun-Jul;31(6-7):581-3. doi: 10.1051/medsci/20153106002. Epub 2015 Jul 7. French. No abstract available.

8.

RBM28, a protein deficient in ANE syndrome, regulates hair follicle growth via miR-203 and p63.

Warshauer E, Samuelov L, Sarig O, Vodo D, Bindereif A, Kanaan M, Gat U, Fuchs-Telem D, Shomron N, Farberov L, Pasmanik-Chor M, Nardini G, Winkler E, Meilik B, Petit I, Aberdam D, Paus R, Sprecher E, Nousbeck J.

Exp Dermatol. 2015 Aug;24(8):618-22. doi: 10.1111/exd.12737. Epub 2015 May 26.

PMID:
25939713
9.

Concise Review: Energy Metabolites: Key Mediators of the Epigenetic State of Pluripotency.

Moussaieff A, Kogan NM, Aberdam D.

Stem Cells. 2015 Aug;33(8):2374-80. doi: 10.1002/stem.2041. Epub 2015 May 26. Review.

10.

Glycolysis-mediated changes in acetyl-CoA and histone acetylation control the early differentiation of embryonic stem cells.

Moussaieff A, Rouleau M, Kitsberg D, Cohen M, Levy G, Barasch D, Nemirovski A, Shen-Orr S, Laevsky I, Amit M, Bomze D, Elena-Herrmann B, Scherf T, Nissim-Rafinia M, Kempa S, Itskovitz-Eldor J, Meshorer E, Aberdam D, Nahmias Y.

Cell Metab. 2015 Mar 3;21(3):392-402. doi: 10.1016/j.cmet.2015.02.002.

11.

A composite enhancer regulates p63 gene expression in epidermal morphogenesis and in keratinocyte differentiation by multiple mechanisms.

Antonini D, Sirico A, Aberdam E, Ambrosio R, Campanile C, Fagoonee S, Altruda F, Aberdam D, Brissette JL, Missero C.

Nucleic Acids Res. 2015 Jan;43(2):862-74. doi: 10.1093/nar/gku1396. Epub 2015 Jan 7.

12.

Inactivation of p53 in Human Keratinocytes Leads to Squamous Differentiation and Shedding via Replication Stress and Mitotic Slippage.

Freije A, Molinuevo R, Ceballos L, Cagigas M, Alonso-Lecue P, Rodriguez R, Menendez P, Aberdam D, De Diego E, Gandarillas A.

Cell Rep. 2014 Nov 20;9(4):1349-60. doi: 10.1016/j.celrep.2014.10.012. Epub 2014 Nov 6.

13.

Human embryonic stem cells prevent T-cell activation by suppressing dendritic cells function via TGF-beta signaling pathway.

Leshansky L, Aberdam D, Itskovitz-Eldor J, Berrih-Aknin S.

Stem Cells. 2014 Dec;32(12):3137-49. doi: 10.1002/stem.1833.

14.

A mutation in TP63 causing a mild ectodermal dysplasia phenotype.

Goldsmith T, Eytan O, Magal L, Solomon M, Israeli S, Warshauer E, Grafi-Cohen M, Aberdam D, van Bokhoven H, Zhou H, Sarig O, Sprecher E, Nousbeck J.

J Invest Dermatol. 2014 Aug;134(8):2277-2280. doi: 10.1038/jid.2014.159. Epub 2014 Mar 27. No abstract available.

15.

The 6th International p63/p73 Workshop: the C(ancer) and D(evelopmental) roles of p63 and p73.

Sabapathy K, Nagakawara A, Aberdam D.

Cell Death Differ. 2014 Aug;21(8):1340-2. doi: 10.1038/cdd.2013.192. Epub 2014 Jan 17. No abstract available.

16.

Argonaute2 mediates compensatory expansion of the pancreatic β cell.

Tattikota SG, Rathjen T, McAnulty SJ, Wessels HH, Akerman I, van de Bunt M, Hausser J, Esguerra JL, Musahl A, Pandey AK, You X, Chen W, Herrera PL, Johnson PR, O'Carroll D, Eliasson L, Zavolan M, Gloyn AL, Ferrer J, Shalom-Feuerstein R, Aberdam D, Poy MN.

Cell Metab. 2014 Jan 7;19(1):122-34. doi: 10.1016/j.cmet.2013.11.015. Epub 2013 Dec 19.

17.

Angiomodulin is required for cardiogenesis of embryonic stem cells and is maintained by a feedback loop network of p63 and Activin-A.

Wolchinsky Z, Shivtiel S, Kouwenhoven EN, Putin D, Sprecher E, Zhou H, Rouleau M, Aberdam D.

Stem Cell Res. 2014 Jan;12(1):49-59. doi: 10.1016/j.scr.2013.09.015. Epub 2013 Oct 6.

18.

Abnormal neuronal differentiation and mitochondrial dysfunction in hair follicle-derived induced pluripotent stem cells of schizophrenia patients.

Robicsek O, Karry R, Petit I, Salman-Kesner N, Müller FJ, Klein E, Aberdam D, Ben-Shachar D.

Mol Psychiatry. 2013 Oct;18(10):1067-76. doi: 10.1038/mp.2013.67. Epub 2013 Jun 4.

PMID:
23732879
19.

Impaired epithelial differentiation of induced pluripotent stem cells from ectodermal dysplasia-related patients is rescued by the small compound APR-246/PRIMA-1MET.

Shalom-Feuerstein R, Serror L, Aberdam E, Müller FJ, van Bokhoven H, Wiman KG, Zhou H, Aberdam D, Petit I.

Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):2152-6. doi: 10.1073/pnas.1201753109. Epub 2013 Jan 25.

20.

A step closer toward therapies for p63-related disorders.

Zhou H, Aberdam D.

Rare Dis. 2013 Mar 12;1:e24247. doi: 10.4161/rdis.24247. eCollection 2013.

21.

miR-24 triggers epidermal differentiation by controlling actin adhesion and cell migration.

Amelio I, Lena AM, Viticchiè G, Shalom-Feuerstein R, Terrinoni A, Dinsdale D, Russo G, Fortunato C, Bonanno E, Spagnoli LG, Aberdam D, Knight RA, Candi E, Melino G.

J Cell Biol. 2012 Oct 15;199(2):347-63. doi: 10.1083/jcb.201203134.

22.

Human mesenchymal stem cells shift CD8+ T cells towards a suppressive phenotype by inducing tolerogenic monocytes.

Hof-Nahor I, Leshansky L, Shivtiel S, Eldor L, Aberdam D, Itskovitz-Eldor J, Berrih-Aknin S.

J Cell Sci. 2012 Oct 1;125(Pt 19):4640-50. doi: 10.1242/jcs.108860. Epub 2012 Jul 5.

23.

RNF20 and USP44 regulate stem cell differentiation by modulating H2B monoubiquitylation.

Fuchs G, Shema E, Vesterman R, Kotler E, Wolchinsky Z, Wilder S, Golomb L, Pribluda A, Zhang F, Haj-Yahya M, Feldmesser E, Brik A, Yu X, Hanna J, Aberdam D, Domany E, Oren M.

Mol Cell. 2012 Jun 8;46(5):662-73. doi: 10.1016/j.molcel.2012.05.023. Erratum in: Mol Cell. 2015 Oct 15;60(2):338.

24.

[The two faces of p63, Janus of the p53 gene family].

Caron de Fromentel C, Aberdam E, Aberdam D.

Med Sci (Paris). 2012 Apr;28(4):381-7. doi: 10.1051/medsci/2012284015. Epub 2012 Apr 25. Review. French.

25.

Pluripotent stem cell model reveals essential roles for miR-450b-5p and miR-184 in embryonic corneal lineage specification.

Shalom-Feuerstein R, Serror L, De La Forest Divonne S, Petit I, Aberdam E, Camargo L, Damour O, Vigouroux C, Solomon A, Gaggioli C, Itskovitz-Eldor J, Ahmad S, Aberdam D.

Stem Cells. 2012 May;30(5):898-909. doi: 10.1002/stem.1068.

26.

microRNA-34a regulates neurite outgrowth, spinal morphology, and function.

Agostini M, Tucci P, Steinert JR, Shalom-Feuerstein R, Rouleau M, Aberdam D, Forsythe ID, Young KW, Ventura A, Concepcion CP, Han YC, Candi E, Knight RA, Mak TW, Melino G.

Proc Natl Acad Sci U S A. 2011 Dec 27;108(52):21099-104. doi: 10.1073/pnas.1112063108. Epub 2011 Dec 12.

27.

Regulation of skin aging and heart development by TAp63.

Paris M, Rouleau M, Pucéat M, Aberdam D.

Cell Death Differ. 2012 Feb;19(2):186-93. doi: 10.1038/cdd.2011.181. Epub 2011 Dec 9. Review.

28.

Induced pluripotent stem cells from hair follicles as a cellular model for neurodevelopmental disorders.

Petit I, Kesner NS, Karry R, Robicsek O, Aberdam E, Müller FJ, Aberdam D, Ben-Shachar D.

Stem Cell Res. 2012 Jan;8(1):134-40. doi: 10.1016/j.scr.2011.09.003. Epub 2011 Oct 7.

29.

Diverse p63 and p73 isoforms regulate Δ133p53 expression through modulation of the internal TP53 promoter activity.

Marcel V, Petit I, Murray-Zmijewski F, Goullet de Rugy T, Fernandes K, Meuray V, Diot A, Lane DP, Aberdam D, Bourdon JC.

Cell Death Differ. 2012 May;19(5):816-26. doi: 10.1038/cdd.2011.152. Epub 2011 Nov 11.

30.

[Unexpected role for p63 during heart development: one phenotype can hide another one].

Rouleau M, Pucéat M, Aberdam D.

Med Sci (Paris). 2011 Oct;27(10):905-9. doi: 10.1051/medsci/20112710023. Epub 2011 Oct 21. Review. French. No abstract available.

31.

TAp63 is important for cardiac differentiation of embryonic stem cells and heart development.

Rouleau M, Medawar A, Hamon L, Shivtiel S, Wolchinsky Z, Zhou H, De Rosa L, Candi E, de la Forest Divonne S, Mikkola ML, van Bokhoven H, Missero C, Melino G, Pucéat M, Aberdam D.

Stem Cells. 2011 Nov;29(11):1672-83. doi: 10.1002/stem.723.

32.

IGFBP7 as a potential therapeutic target in Psoriasis.

Nousbeck J, Ishida-Yamamoto A, Bidder M, Fuchs D, Eckl K, Hennies HC, Sagiv N, Gat A, Gini M, Filip I, Matz H, Goldberg I, Enk CD, Sarig O, Meilik B, Aberdam D, Gilhar A, Sprecher E.

J Invest Dermatol. 2011 Aug;131(8):1767-70. doi: 10.1038/jid.2011.108. Epub 2011 May 12. No abstract available.

33.

ΔNp63 is an ectodermal gatekeeper of epidermal morphogenesis.

Shalom-Feuerstein R, Lena AM, Zhou H, De La Forest Divonne S, Van Bokhoven H, Candi E, Melino G, Aberdam D.

Cell Death Differ. 2011 May;18(5):887-96. doi: 10.1038/cdd.2010.159. Epub 2010 Dec 3.

34.

Embryonic stem cells as an ectodermal cellular model of human p63-related dysplasia syndromes.

Rostagno P, Wolchinsky Z, Vigano AM, Shivtiel S, Zhou H, Van Bokhoven H, Ferone G, Missero C, Mantovani R, Aberdam D, Virolle T.

Biochem Biophys Res Commun. 2010 Apr 23;395(1):131-5. doi: 10.1016/j.bbrc.2010.03.154. Epub 2010 Mar 30.

PMID:
20361935
35.

miR-7 and miR-214 are specifically expressed during neuroblastoma differentiation, cortical development and embryonic stem cells differentiation, and control neurite outgrowth in vitro.

Chen H, Shalom-Feuerstein R, Riley J, Zhang SD, Tucci P, Agostini M, Aberdam D, Knight RA, Genchi G, Nicotera P, Melino G, Vasa-Nicotera M.

Biochem Biophys Res Commun. 2010 Apr 16;394(4):921-7. doi: 10.1016/j.bbrc.2010.03.076. Epub 2010 Mar 15.

PMID:
20230785
36.

A new p63-deficient mouse model or a fresh look at an old one?

Aberdam D, Mantovani R.

Cell Death Differ. 2009 Aug;16(8):1073-4. doi: 10.1038/cdd.2009.66. No abstract available.

37.

Three-dimensional epithelial tissues generated from human embryonic stem cells.

Hewitt KJ, Shamis Y, Carlson MW, Aberdam E, Aberdam D, Garlick JA.

Tissue Eng Part A. 2009 Nov;15(11):3417-26. doi: 10.1089/ten.TEA.2009.0060.

38.

ATF3 and p15PAF are novel gatekeepers of genomic integrity upon UV stress.

Turchi L, Fareh M, Aberdam E, Kitajima S, Simpson F, Wicking C, Aberdam D, Virolle T.

Cell Death Differ. 2009 May;16(5):728-37. doi: 10.1038/cdd.2009.2. Epub 2009 Feb 13.

39.

DeltaNp63 is essential for epidermal commitment of embryonic stem cells.

Medawar A, Virolle T, Rostagno P, de la Forest-Divonne S, Gambaro K, Rouleau M, Aberdam D.

PLoS One. 2008;3(10):e3441. doi: 10.1371/journal.pone.0003441. Epub 2008 Oct 17.

40.

miRNAs, 'stemness' and skin.

Aberdam D, Candi E, Knight RA, Melino G.

Trends Biochem Sci. 2008 Dec;33(12):583-91. doi: 10.1016/j.tibs.2008.09.002. Epub 2008 Oct 8. Review.

PMID:
18848452
41.

Hif-2alpha mediates UV-induced apoptosis through a novel ATF3-dependent death pathway.

Turchi L, Aberdam E, Mazure N, Pouysségur J, Deckert M, Kitajima S, Aberdam D, Virolle T.

Cell Death Differ. 2008 Sep;15(9):1472-80. doi: 10.1038/cdd.2008.74. Epub 2008 May 30.

42.

miR-203 represses 'stemness' by repressing DeltaNp63.

Lena AM, Shalom-Feuerstein R, Rivetti di Val Cervo P, Aberdam D, Knight RA, Melino G, Candi E.

Cell Death Differ. 2008 Jul;15(7):1187-95. doi: 10.1038/cdd.2008.69. Epub 2008 May 16.

43.

[Embryonic stem cells and skin: from cellular model to therapeutic potential].

Aberdam E, Aberdam D.

J Soc Biol. 2008;202(1):15-23. doi: 10.1051/jbio:2008003. Epub 2008 May 8. French.

PMID:
18460305
44.

A pure population of ectodermal cells derived from human embryonic stem cells.

Aberdam E, Barak E, Rouleau M, de LaForest S, Berrih-Aknin S, Suter DM, Krause KH, Amit M, Itskovitz-Eldor J, Aberdam D.

Stem Cells. 2008 Feb;26(2):440-4. Epub 2007 Nov 21.

45.

[To repair or to regenerate, it is necessary to choose...].

Aberdam D.

Med Sci (Paris). 2007 Oct;23(10):791-3. French. No abstract available.

46.

Epidermal stem cell fate: what can we learn from embryonic stem cells?

Aberdam D.

Cell Tissue Res. 2008 Jan;331(1):103-7. Epub 2007 Sep 6. Review.

PMID:
17805576
47.

Embryonic stem cells as a cellular model for neuroectodermal commitment and skin formation.

Aberdam D, Gambaro K, Medawar A, Aberdam E, Rostagno P, de la Forest Divonne S, Rouleau M.

C R Biol. 2007 Jun-Jul;330(6-7):479-84. Epub 2007 Apr 16. Review.

PMID:
17631441
48.

Key role of p63 in BMP-4-induced epidermal commitment of embryonic stem cells.

Aberdam D, Gambaro K, Rostagno P, Aberdam E, de la Forest Divonne S, Rouleau M.

Cell Cycle. 2007 Feb 1;6(3):291-4. Epub 2007 Feb 3. Review.

PMID:
17264680
49.

SEDEM, a software package for EXAFS data extraction and modelling.

Aberdam D.

J Synchrotron Radiat. 1998 Sep 1;5(Pt 5):1287-97.

PMID:
16687836
50.

BMP-4 induces a Smad-dependent apoptotic cell death of mouse embryonic stem cell-derived neural precursors.

Gambaro K, Aberdam E, Virolle T, Aberdam D, Rouleau M.

Cell Death Differ. 2006 Jul;13(7):1075-87. Epub 2005 Nov 25.

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