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Unexpected stability of aqueous dispersions of raspberry-like colloids.

Lan Y, Caciagli A, Guidetti G, Yu Z, Liu J, Johansen VE, Kamp M, Abell C, Vignolini S, Scherman OA, Eiser E.

Nat Commun. 2018 Sep 6;9(1):3614. doi: 10.1038/s41467-018-05560-3.


Cucurbit[7]uril-based high-performance catalytic microreactors.

Ren X, Yu Z, Wu Y, Liu J, Abell C, Scherman OA.

Nanoscale. 2018 Aug 9;10(31):14835-14839. doi: 10.1039/c8nr02900h.


Droplet-based microfluidic analysis and screening of single plant cells.

Yu Z, Boehm CR, Hibberd JM, Abell C, Haseloff J, Burgess SJ, Reyna-Llorens I.

PLoS One. 2018 May 3;13(5):e0196810. doi: 10.1371/journal.pone.0196810. eCollection 2018.


Fragment-Based Approach to Targeting Inosine-5'-monophosphate Dehydrogenase (IMPDH) from Mycobacterium tuberculosis.

Trapero A, Pacitto A, Singh V, Sabbah M, Coyne AG, Mizrahi V, Blundell TL, Ascher DB, Abell C.

J Med Chem. 2018 Apr 12;61(7):2806-2822. doi: 10.1021/acs.jmedchem.7b01622. Epub 2018 Mar 23.


Nurses' Perceptions of Competence in Providing Spiritual Care.

Abell CH, Garrett-Wright D, Abell CE.

J Holist Nurs. 2018 Mar;36(1):33-37. doi: 10.1177/0898010116684960. Epub 2017 Jan 1.


Droplet microfluidics for the highly controlled synthesis of branched gold nanoparticles.

Abalde-Cela S, Taladriz-Blanco P, de Oliveira MG, Abell C.

Sci Rep. 2018 Feb 5;8(1):2440. doi: 10.1038/s41598-018-20754-x.


Supramolecular Nested Microbeads as Building Blocks for Macroscopic Self-Healing Scaffolds.

Yu Z, Liu J, Tan CSY, Scherman OA, Abell C.

Angew Chem Int Ed Engl. 2018 Mar 12;57(12):3079-3083. doi: 10.1002/anie.201711522. Epub 2018 Feb 21.


Target Identification of Mycobacterium tuberculosis Phenotypic Hits Using a Concerted Chemogenomic, Biophysical, and Structural Approach.

Mugumbate G, Mendes V, Blaszczyk M, Sabbah M, Papadatos G, Lelievre J, Ballell L, Barros D, Abell C, Blundell TL, Overington JP.

Front Pharmacol. 2017 Sep 26;8:681. doi: 10.3389/fphar.2017.00681. eCollection 2017.


Mass spectrometry for fragment screening.

Chan DS, Whitehouse AJ, Coyne AG, Abell C.

Essays Biochem. 2017 Nov 8;61(5):465-473. doi: 10.1042/EBC20170071. Print 2017 Nov 8. Review.


Effect of DMSO on Protein Structure and Interactions Assessed by Collision-Induced Dissociation and Unfolding.

Chan DS, Kavanagh ME, McLean KJ, Munro AW, Matak-Vinković D, Coyne AG, Abell C.

Anal Chem. 2017 Sep 19;89(18):9976-9983. doi: 10.1021/acs.analchem.7b02329. Epub 2017 Aug 25.


Bioinspired supramolecular fibers drawn from a multiphase self-assembled hydrogel.

Wu Y, Shah DU, Liu C, Yu Z, Liu J, Ren X, Rowland MJ, Abell C, Ramage MH, Scherman OA.

Proc Natl Acad Sci U S A. 2017 Aug 1;114(31):8163-8168. doi: 10.1073/pnas.1705380114. Epub 2017 Jul 10.


Fragment Screening against the EthR-DNA Interaction by Native Mass Spectrometry.

Chan DS, Mendes V, Thomas SE, McConnell BN, Matak-Vinković D, Coyne AG, Blundell TL, Abell C.

Angew Chem Int Ed Engl. 2017 Jun 19;56(26):7488-7491. doi: 10.1002/anie.201702888. Epub 2017 May 31.


Specific inhibition of CK2α from an anchor outside the active site.

Brear P, De Fusco C, Hadje Georgiou K, Francis-Newton NJ, Stubbs CJ, Sore HF, Venkitaraman AR, Abell C, Spring DR, Hyvönen M.

Chem Sci. 2016 Nov 1;7(11):6839-6845. doi: 10.1039/c6sc02335e. Epub 2016 Jul 12.


Tough Supramolecular Polymer Networks with Extreme Stretchability and Fast Room-Temperature Self-Healing.

Liu J, Tan CSY, Yu Z, Li N, Abell C, Scherman OA.

Adv Mater. 2017 Jun;29(22). doi: 10.1002/adma.201605325. Epub 2017 Apr 3.


The biochemical properties of the two Arabidopsis thaliana isochorismate synthases.

Macaulay KM, Heath GA, Ciulli A, Murphy AM, Abell C, Carr JP, Smith AG.

Biochem J. 2017 Apr 28;474(10):1579-1590. doi: 10.1042/BCJ20161069.


Corrigendum: Surface mediated cooperative interactions of drugs enhance mechanical forces for antibiotic action.

Ndieyira JW, Bailey J, Patil SB, Vögtli M, Cooper MA, Abell C, McKendry RA, Aeppli G.

Sci Rep. 2017 Mar 23;7:43980. doi: 10.1038/srep43980. No abstract available.


Fragment-Sized EthR Inhibitors Exhibit Exceptionally Strong Ethionamide Boosting Effect in Whole-Cell Mycobacterium tuberculosis Assays.

Nikiforov PO, Blaszczyk M, Surade S, Boshoff HI, Sajid A, Delorme V, Deboosere N, Brodin P, Baulard AR, Barry CE 3rd, Blundell TL, Abell C.

ACS Chem Biol. 2017 May 19;12(5):1390-1396. doi: 10.1021/acschembio.7b00091. Epub 2017 Apr 5.


Structural insights into the EthR-DNA interaction using native mass spectrometry.

Shiu-Hin Chan D, Seetoh WG, McConnell BN, Matak-Vinković D, Thomas SE, Mendes V, Blaszczyk M, Coyne AG, Blundell TL, Abell C.

Chem Commun (Camb). 2017 Mar 23;53(25):3527-3530. doi: 10.1039/c7cc00804j.


Fragment Profiling Approach to Inhibitors of the Orphan M. tuberculosis P450 CYP144A1.

Kavanagh ME, Chenge J, Zoufir A, McLean KJ, Coyne AG, Bender A, Munro AW, Abell C.

Biochemistry. 2017 Mar 21;56(11):1559-1572. doi: 10.1021/acs.biochem.6b00954. Epub 2017 Mar 6.


Surface mediated cooperative interactions of drugs enhance mechanical forces for antibiotic action.

Ndieyira JW, Bailey J, Patil SB, Vögtli M, Cooper MA, Abell C, McKendry RA, Aeppli G.

Sci Rep. 2017 Feb 3;7:41206. doi: 10.1038/srep41206. Erratum in: Sci Rep. 2017 Mar 23;7:43980.


Aqueous interfacial gels assembled from small molecule supramolecular polymers.

Groombridge AS, Palma A, Parker RM, Abell C, Scherman OA.

Chem Sci. 2017 Feb 1;8(2):1350-1355. doi: 10.1039/c6sc04103e. Epub 2016 Oct 11.


Corrigendum: Substrate Fragmentation for the Design of M. tuberculosis CYP121 Inhibitors.

Kavanagh ME, Gray JL, Gilbert SH, Coyne AG, McLean KJ, Davis HJ, Munro AW, Abell C.

ChemMedChem. 2017 Jan 20;12(2):194-195. doi: 10.1002/cmdc.201600619. Epub 2016 Dec 19. No abstract available.


Biomimetic Supramolecular Polymer Networks Exhibiting both Toughness and Self-Recovery.

Liu J, Tan CS, Yu Z, Lan Y, Abell C, Scherman OA.

Adv Mater. 2017 Mar;29(10). doi: 10.1002/adma.201604951. Epub 2017 Jan 16.


Cucurbit[n]uril-Based Microcapsules Self-Assembled within Microfluidic Droplets: A Versatile Approach for Supramolecular Architectures and Materials.

Liu J, Lan Y, Yu Z, Tan CS, Parker RM, Abell C, Scherman OA.

Acc Chem Res. 2017 Feb 21;50(2):208-217. doi: 10.1021/acs.accounts.6b00429. Epub 2017 Jan 11.


Structural Characterization and Ligand/Inhibitor Identification Provide Functional Insights into the Mycobacterium tuberculosis Cytochrome P450 CYP126A1.

Chenge JT, Duyet LV, Swami S, McLean KJ, Kavanagh ME, Coyne AG, Rigby SE, Cheesman MR, Girvan HM, Levy CW, Rupp B, von Kries JP, Abell C, Leys D, Munro AW.

J Biol Chem. 2017 Jan 27;292(4):1310-1329. doi: 10.1074/jbc.M116.748822. Epub 2016 Dec 8.


Antagonists of the miRNA-Argonaute 2 Protein Complex: Anti-miR-AGOs.

Schmidt MF, Korb O, Abell C.

Methods Mol Biol. 2017;1517:239-249.


Fragment-based approaches to TB drugs.

Marchetti C, Chan DSH, Coyne AG, Abell C.

Parasitology. 2018 Feb;145(2):184-195. doi: 10.1017/S0031182016001876. Epub 2016 Nov 2.


Label-Free Analysis and Sorting of Microalgae and Cyanobacteria in Microdroplets by Intrinsic Chlorophyll Fluorescence for the Identification of Fast Growing Strains.

Best RJ, Lyczakowski JJ, Abalde-Cela S, Yu Z, Abell C, Smith AG.

Anal Chem. 2016 Nov 1;88(21):10445-10451. Epub 2016 Oct 21.


Participants' Perceptions of Worksite Health-Promotion Educational Activities.

Abell CH, Main ME.

J Community Health Nurs. 2016 Oct-Dec;33(4):190-195.


Engineering Archeal Surrogate Systems for the Development of Protein-Protein Interaction Inhibitors against Human RAD51.

Moschetti T, Sharpe T, Fischer G, Marsh ME, Ng HK, Morgan M, Scott DE, Blundell TL, R Venkitaraman A, Skidmore J, Abell C, Hyvönen M.

J Mol Biol. 2016 Nov 20;428(23):4589-4607. doi: 10.1016/j.jmb.2016.10.009. Epub 2016 Oct 8.


Microcapsule Buckling Triggered by Compression-Induced Interfacial Phase Change.

Salmon AR, Parker RM, Groombridge AS, Maestro A, Coulston RJ, Hegemann J, Kierfeld J, Scherman OA, Abell C.

Langmuir. 2016 Oct 4. [Epub ahead of print]


Genetic relationship between purebred and crossbred sow longevity.

Abell CE, Fernando RL, Serenius TV, Rothschild MF, Gray KA, Stalder KJ.

J Anim Sci Biotechnol. 2016 Sep 6;7(1):51. doi: 10.1186/s40104-016-0112-x. eCollection 2016.


Hierarchical Self-Assembly of Cellulose Nanocrystals in a Confined Geometry.

Parker RM, Frka-Petesic B, Guidetti G, Kamita G, Consani G, Abell C, Vignolini S.

ACS Nano. 2016 Sep 27;10(9):8443-9. doi: 10.1021/acsnano.6b03355. Epub 2016 Aug 31.


A Unique Clinical Experience for RN-to-BSN Students: Providing Farm Safety Education.

Abell CH, Evans C, Alexander L, Bourne K, Jones MS.

J Nurs Educ. 2016 Sep 1;55(9):544. doi: 10.3928/01484834-20160816-11. No abstract available.


Substrate Fragmentation for the Design of M. tuberculosis CYP121 Inhibitors.

Kavanagh ME, Gray JL, Gilbert SH, Coyne AG, McLean KJ, Davis HJ, Munro AW, Abell C.

ChemMedChem. 2016 Sep 6;11(17):1924-35. doi: 10.1002/cmdc.201600248. Epub 2016 Jul 19. Erratum in: ChemMedChem. 2017 Jan 20;12 (2):194-195.


ATP half-sites in RadA and RAD51 recombinases bind nucleotides.

Marsh ME, Scott DE, Ehebauer MT, Abell C, Blundell TL, Hyvönen M.

FEBS Open Bio. 2016 Apr 6;6(5):372-85. doi: 10.1002/2211-5463.12052. eCollection 2016 May.


Inhibition of Ral GTPases Using a Stapled Peptide Approach.

Thomas JC, Cooper JM, Clayton NS, Wang C, White MA, Abell C, Owen D, Mott HR.

J Biol Chem. 2016 Aug 26;291(35):18310-25. doi: 10.1074/jbc.M116.720243. Epub 2016 Jun 22.


Selective small molecule inhibitor of the Mycobacterium tuberculosis fumarate hydratase reveals an allosteric regulatory site.

Kasbekar M, Fischer G, Mott BT, Yasgar A, Hyvönen M, Boshoff HI, Abell C, Barry CE 3rd, Thomas CJ.

Proc Natl Acad Sci U S A. 2016 Jul 5;113(27):7503-8. doi: 10.1073/pnas.1600630113. Epub 2016 Jun 20.


Spirooxindoles as novel 3D-fragment scaffolds: Synthesis and screening against CYP121 from M. tuberculosis.

Davis HJ, Kavanagh ME, Balan T, Abell C, Coyne AG.

Bioorg Med Chem Lett. 2016 Aug 1;26(15):3735-40. doi: 10.1016/j.bmcl.2016.05.073. Epub 2016 May 26.


Structural characterization of CYP144A1 - a cytochrome P450 enzyme expressed from alternative transcripts in Mycobacterium tuberculosis.

Chenge J, Kavanagh ME, Driscoll MD, McLean KJ, Young DB, Cortes T, Matak-Vinkovic D, Levy CW, Rigby SE, Leys D, Abell C, Munro AW.

Sci Rep. 2016 May 26;6:26628. doi: 10.1038/srep26628.


Small molecules, big targets: drug discovery faces the protein-protein interaction challenge.

Scott DE, Bayly AR, Abell C, Skidmore J.

Nat Rev Drug Discov. 2016 Aug;15(8):533-50. doi: 10.1038/nrd.2016.29. Epub 2016 Apr 11. Review.


Fragment-Based Approaches to the Development of Mycobacterium tuberculosis CYP121 Inhibitors.

Kavanagh ME, Coyne AG, McLean KJ, James GG, Levy CW, Marino LB, de Carvalho LP, Chan DS, Hudson SA, Surade S, Leys D, Munro AW, Abell C.

J Med Chem. 2016 Apr 14;59(7):3272-302. doi: 10.1021/acs.jmedchem.6b00007. Epub 2016 Mar 22.


Mass Spectrometry Reveals Protein Kinase CK2 High-Order Oligomerization via the Circular and Linear Assembly.

Seetoh WG, Chan DS, Matak-Vinković D, Abell C.

ACS Chem Biol. 2016 Jun 17;11(6):1511-7. doi: 10.1021/acschembio.6b00064. Epub 2016 Mar 29.


Structure-activity relationship of the peptide binding-motif mediating the BRCA2:RAD51 protein-protein interaction.

Scott DE, Marsh M, Blundell TL, Abell C, Hyvönen M.

FEBS Lett. 2016 Apr;590(8):1094-102. doi: 10.1002/1873-3468.12139. Epub 2016 Apr 6.


Microfluidic Droplet-Facilitated Hierarchical Assembly for Dual Cargo Loading and Synergistic Delivery.

Yu Z, Zheng Y, Parker RM, Lan Y, Wu Y, Coulston RJ, Zhang J, Scherman OA, Abell C.

ACS Appl Mater Interfaces. 2016 Apr 6;8(13):8811-20. doi: 10.1021/acsami.6b00661. Epub 2016 Mar 25.


Monitoring Early-Stage Nanoparticle Assembly in Microdroplets by Optical Spectroscopy and SERS.

Salmon AR, Esteban R, Taylor RW, Hugall JT, Smith CA, Whyte G, Scherman OA, Aizpurua J, Abell C, Baumberg JJ.

Small. 2016 Apr 6;12(13):1788-96. doi: 10.1002/smll.201503513. Epub 2016 Feb 10.


A fragment merging approach towards the development of small molecule inhibitors of Mycobacterium tuberculosis EthR for use as ethionamide boosters.

Nikiforov PO, Surade S, Blaszczyk M, Delorme V, Brodin P, Baulard AR, Blundell TL, Abell C.

Org Biomol Chem. 2016 Feb 21;14(7):2318-26. doi: 10.1039/c5ob02630j. Epub 2016 Jan 25.


Structure-Based Identification of Inhibitory Fragments Targeting the p300/CBP-Associated Factor Bromodomain.

Chaikuad A, Lang S, Brennan PE, Temperini C, Fedorov O, Hollander J, Nachane R, Abell C, Müller S, Siegal G, Knapp S.

J Med Chem. 2016 Feb 25;59(4):1648-53. doi: 10.1021/acs.jmedchem.5b01719. Epub 2016 Jan 13.


The Application of Ligand-Mapping Molecular Dynamics Simulations to the Rational Design of Peptidic Modulators of Protein-Protein Interactions.

Tan YS, Spring DR, Abell C, Verma CS.

J Chem Theory Comput. 2015 Jul 14;11(7):3199-210. doi: 10.1021/ct5010577. Epub 2015 Jun 22.


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